Pou3f1 (Mus musculus)
Homeodomain,POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00157 (Pou) 		IPR001356
IPR000327 		ENSMUSG00000090125 T238384_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA binding activity. Involved in positive regulation of gene expression and positive regulation of transcription, DNA-templated. Acts upstream of or within forebrain development; keratinocyte differentiation; and myelination in peripheral nervous system. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; sensory organ; and urinary system. Orthologous to human POU3F1 (POU class 3 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Pou3f1
M00551_2.00		 Mus musculus
NNWWATKNN
NNMATWWNN		 PBM
Berger et al.(2008)
Pou3f1_3819		 (Direct) (Direct)
Pou3f1
M00804_2.00		 Mus musculus
NNWAATKHN
NDMATTWNN		 PBM
Weirauch et al.(2013)
pTH3819		 (Direct) (Direct)
Pou3f1
M09227_2.00		 Mus musculus
BWHATGMAWAWKBMWD
HWKVMWTWTKCATDWV		 Misc
Kulakovskiy et al.(2013)
PO3F1_MOUSE.H11MO.0.C		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
POU3F1
M03315_2.00 		Homo sapiens
WTATGYWAATDN
NHATTWRCATAW		 SELEX
Jolma et al.(2013)
POU3F1_1 		1.000 1.000
POU3F1
M03316_2.00 		Homo sapiens
WTGMATAWWDHA
TDHWWTATKCAW		 SELEX
Jolma et al.(2013)
POU3F1_2 		1.000 1.000
POU3F1
M05483_2.00 		Homo sapiens
YAATTRVNNNBYAATTR
YAATTRVNNNBYAATTR		 SELEX
Yin et al.(2017)
POU3F1_eDBD_HT-SELEX_1 		1.000 1.000
POU3F1
M05484_2.00 		Homo sapiens
NTAATBDBVTGCRN
NYGCABVHVATTAN		 SELEX
Yin et al.(2017)
POU3F1_eDBD_HT-SELEX_2 		1.000 1.000
POU3F1
M05485_2.00 		Homo sapiens
NTAATKWABKCDN
NHGMVTWMATTAN		 SELEX
Yin et al.(2017)
POU3F1_eDBD_HT-SELEX_3 		1.000 1.000
POU3F1
M05486_2.00 		Homo sapiens
NHATGYWAATNNN
NNNATTWRCATDN		 SELEX
Yin et al.(2017)
POU3F1_eDBD_HT-SELEX_4 		1.000 1.000
POU3F1
M09221_2.00 		Homo sapiens
VRTKSWWATGCDWD
HWHGCATWWSMAYB		 Misc
Kulakovskiy et al.(2013)
PO3F1_HUMAN.H11MO.0.C 		1.000 1.000
POU3F1
M10847_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$POU3F1_Q2 		1.000 1.000
POU3F1
M10848_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$POU3F1_Q6 		1.000 1.000
POU3F1
M10849_2.00 		Homo sapiens
NHABTBWWAWTSMNN
NNKSAWTWAVAVTDN		 Transfac
Matys et al.(2006)
V$TST1_01 		1.000 1.000
POU3F1
M05487_2.00 		Homo sapiens
NTAATGAKATGCRH
DYGCATMTCATTAN		 SELEX
Yin et al.(2017)
POU3F1_eDBD_Methyl-HT-SELEX_1 		1.000 1.000
POU3F1
M05488_2.00 		Homo sapiens
DCGCATAAATTAN
NTAATTTATGCGH		 SELEX
Yin et al.(2017)
POU3F1_eDBD_Methyl-HT-SELEX_2 		1.000 1.000
POU3F1
M05489_2.00 		Homo sapiens
DWATGCGCATWH
DWATGCGCATWH		 SELEX
Yin et al.(2017)
POU3F1_eDBD_Methyl-HT-SELEX_3 		1.000 1.000
POU3F1
M05490_2.00 		Homo sapiens
WTATGCWAATKAG
CTMATTWGCATAW		 SELEX
Yin et al.(2017)
POU3F1_eDBD_Methyl-HT-SELEX_4 		1.000 1.000
POU3F1
M05491_2.00 		Homo sapiens
TMAWKWNNNNNWMATTA
TAATKWNNNNNWMWTKA		 SELEX
Yin et al.(2017)
POU3F1_eDBD_Methyl-HT-SELEX_5 		1.000 1.000
For this family, TFs with SR scores > 0.993 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00551_2.00 POU 19 90
M00551_2.00 Homeodomain 109 165
M00804_2.00 POU 19 90
M00804_2.00 Homeodomain 109 165

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000137374 POU 248 319
ENSMUSP00000137374 Homeodomain 338 394

Links

Other Homeodomain,POU family TFs
Other Mus musculus TFs

Invalid Input OrderBy

17 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action