CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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ENSP00000342931
(
Macaca fascicularis
)
Homeodomain,POU
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
PF00046 (Homeobox)
PF00157 (Pou)
IPR001356
IPR000327
ENSP00000342931
T238936_2.00
GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
POU1F1
M03300_2.00
Homo sapiens
NNNWTGMATAWWYHANN
NNTDRWWTATKCAWNNN
SELEX
Jolma et al.(2013)
POU1F1_1
1.000
1.000
POU1F1
M03301_2.00
Homo sapiens
DWTATGCWAATKAD
HTMATTWGCATAWH
SELEX
Jolma et al.(2013)
POU1F1_2
1.000
1.000
POU1F1
M05453_2.00
Homo sapiens
NTAATKAKATGCRN
NYGCATMTMATTAN
SELEX
Yin et al.(2017)
POU1F1_eDBD_HT-SELEX_1
1.000
1.000
POU1F1
M05454_2.00
Homo sapiens
NYGMATAAATTAN
NTAATTTATKCRN
SELEX
Yin et al.(2017)
POU1F1_eDBD_HT-SELEX_2
1.000
1.000
POU1F1
M05455_2.00
Homo sapiens
DTATGCWAATKAVN
NBTMATTWGCATAH
SELEX
Yin et al.(2017)
POU1F1_eDBD_HT-SELEX_3
1.000
1.000
POU1F1
M10822_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PIT1_Q6_01
1.000
1.000
POU1F1
M10823_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PIT1_Q6
1.000
1.000
POU1F1
M10824_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$POU1F1_Q6
1.000
1.000
POU1F1
M05456_2.00
Homo sapiens
NTAATGAKATGCRH
DYGCATMTCATTAN
SELEX
Yin et al.(2017)
POU1F1_eDBD_Methyl-HT-SELEX_1
1.000
1.000
POU1F1
M05457_2.00
Homo sapiens
DCGMATAAATTAN
NTAATTTATKCGH
SELEX
Yin et al.(2017)
POU1F1_eDBD_Methyl-HT-SELEX_2
1.000
1.000
POU1F1
M05458_2.00
Homo sapiens
WTATGCWAATKAGN
NCTMATTWGCATAW
SELEX
Yin et al.(2017)
POU1F1_eDBD_Methyl-HT-SELEX_3
1.000
1.000
For this family, TFs with SR scores >
0.993
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000342931
POU
153
224
PEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAE
ENSP00000342931
Homeodomain
241
297
RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKR
Links
Other
Homeodomain,POU
family TFs
Other
Macaca fascicularis
TFs
22 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy