Hsf3 (Mus musculus)
HSF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00447 (HSF_DNA-bind) IPR000232 ENSMUSG00000045802 T240322_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables chromatin DNA binding activity and sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within cellular response to heat. Located in cytoplasm and nucleus. Is expressed in eye; genital tubercle; genitourinary system; heart; and limb. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hsf2
M09231_2.00 		Mus musculus
VGAABVTTCKVGAN
NTCBMGAABVTTCB		 Misc
Kulakovskiy et al.(2013)
HSF2_MOUSE.H11MO.0.A 		0.346 0.552
HSF1
M03329_2.00 		Homo sapiens
GAANVTTCBVGAA
TTCBVGAABNTTC		 SELEX
Jolma et al.(2013)
HSF1_1 		0.345 0.573
HSF1
M03330_2.00 		Homo sapiens
GAANRTTCBAGAA
TTCTVGAAYNTTC		 SELEX
Jolma et al.(2013)
HSF1_2 		0.345 0.573
HSF1
M05523_2.00 		Homo sapiens
VGAABVTTCBVGAWN
NWTCBVGAABVTTCB		 SELEX
Yin et al.(2017)
HSF1_eDBD_HT-SELEX 		0.345 0.573
HSF1
M05525_2.00 		Homo sapiens
VGAANRTTCKVGAAN
NTTCBMGAAYNTTCB		 SELEX
Yin et al.(2017)
HSF1_FL_HT-SELEX 		0.345 0.573
HSF1
M07977_2.00 		Homo sapiens
GDCSYGGGTTCRADYCCC
GGGRHTYGAACCCRSGHC		 ChIP-seq
Gerstein et al.(2012)
HepG2_HSF1_Stanford 		0.345 0.573
HSF1
M09230_2.00 		Homo sapiens
NRGAANNTTCYRGAA
TTCYRGAANNTTCYN		 Misc
Kulakovskiy et al.(2013)
HSF1_HUMAN.H11MO.0.A 		0.345 0.573
Hsf1
M09232_2.00 		Mus musculus
NRGAANNTTCYRGAA
TTCYRGAANNTTCYN		 Misc
Kulakovskiy et al.(2013)
HSF1_MOUSE.H11MO.0.A 		0.345 0.573
HSF1
M09592_2.00 		Homo sapiens
NNBBCYRGAANNTTCYRGVV
BBCYRGAANNTTCYRGVVNN		 Misc
Heinz et al.(2010)
HepG2-HSF1_GSE31477 		0.345 0.573
Hsf1
M09593_2.00 		Mus musculus
NRGAANNTTCYRGAA
TTCYRGAANNTTCYN		 Misc
Heinz et al.(2010)
Striatum-HSF1_GSE38000 		0.345 0.573
HSF1
M10863_2.00 		Homo sapiens
NGAAHNTTCY
RGAANDTTCN		 Transfac
Matys et al.(2006)
V$HSF1_01 		0.345 0.573
HSF1
M10864_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HSF1_Q5_01 		0.345 0.573
HSF1
M10865_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HSF1_Q5 		0.345 0.573
HSF1
M10866_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HSF1_Q6_01 		0.345 0.573
HSF1
M10867_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HSF1_Q6 		0.345 0.573
HSF1
M10868_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HSF_Q6 		0.345 0.573
HSF1
M05524_2.00 		Homo sapiens
RGAANRTTCYRGAWN
NWTCYRGAAYNTTCY		 SELEX
Yin et al.(2017)
HSF1_eDBD_Methyl-HT-SELEX 		0.345 0.573
HSF1
M05526_2.00 		Homo sapiens
RGAANVTTCYRGAWN
NWTCYRGAABNTTCY		 SELEX
Yin et al.(2017)
HSF1_FL_Methyl-HT-SELEX 		0.345 0.573
hsf2
M02248_2.00 		Danio rerio
NNNWGTTCTATNN
NNATAGAACWNNN		 PBM
Weirauch et al.(2014)
pTH9010 		0.343 0.562
HSF2
M03324_2.00 		Homo sapiens
GAANVTTCTAGAA
TTCTAGAABNTTC		 SELEX
Jolma et al.(2013)
HSF2_1 		0.341 0.552
HSF2
M02744_2.00 		Homo sapiens
GAABGTTCTRGA
TCYAGAACVTTC		 SELEX
Jolma et al.(2010)
HSF2_dimertrimer 		0.341 0.552
HSF2
M05505_2.00 		Homo sapiens
VGAABVTTCBVGAWN
NWTCBVGAABVTTCB		 SELEX
Yin et al.(2017)
HSF2_eDBD_HT-SELEX 		0.341 0.552
HSF2
M05507_2.00 		Homo sapiens
VGAANNTTCBVGAAN
NTTCBVGAANNTTCB		 SELEX
Yin et al.(2017)
HSF2_FL_HT-SELEX 		0.341 0.552
HSF2
M09229_2.00 		Homo sapiens
VGAABVTTCKVGAN
NTCBMGAABVTTCB		 Misc
Kulakovskiy et al.(2013)
HSF2_HUMAN.H11MO.0.A 		0.341 0.552
HSF2
M10859_2.00 		Homo sapiens
VGAANNWTCB
VGAWNNTTCB		 Transfac
Matys et al.(2006)
V$HSF2_01 		0.341 0.552
HSF2
M10860_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HSF2_02 		0.341 0.552
HSF2
M10861_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HSF2_Q6 		0.341 0.552
HSF2
M05506_2.00 		Homo sapiens
RGAABVTTCYRGAWN
NWTCYRGAABVTTCY		 SELEX
Yin et al.(2017)
HSF2_eDBD_Methyl-HT-SELEX 		0.341 0.552
HSF2
M05508_2.00 		Homo sapiens
RGAABVTTCYRGAWN
NWTCYRGAABVTTCY		 SELEX
Yin et al.(2017)
HSF2_FL_Methyl-HT-SELEX 		0.341 0.552
HSF4
M03325_2.00 		Homo sapiens
GAANNTTCBVGAA
TTCBVGAANNTTC		 SELEX
Jolma et al.(2013)
HSF4_1 		0.327 0.531
HSF4
M05509_2.00 		Homo sapiens
VGAABVTTCKVGAAN
NTTCBMGAABVTTCB		 SELEX
Yin et al.(2017)
HSF4_eDBD_HT-SELEX 		0.327 0.531
HSF4
M10862_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HSF4_Q3 		0.327 0.531
HSF4
M05510_2.00 		Homo sapiens
RGAABVWDCYRGAWN
NWTCYRGHWBVTTCY		 SELEX
Yin et al.(2017)
HSF4_eDBD_Methyl-HT-SELEX 		0.327 0.531
For this family, TFs with SR scores > 0.318 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000052508 HSF 12 113
ENSMUSP00000114018 HSF 1 45
ENSMUSP00000132248 HSF 18 102
ENSMUSP00000137314 HSF 1 45

Links

Other HSF family TFs
Other Mus musculus TFs

192 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSDNOG00000048985 Dasypus novemcinctus ENSDNOG00000048985 I 0.403
ENSGMOG00000014148 Gadus morhua ENSGMOG00000014148 I 0.379
ENSACAG00000003529 Anolis carolinensis ENSACAG00000003529 I 0.371
ENSSTOG00000021693 Ictidomys tridecemlineatus ENSSTOG00000021693 I 0.369
ENSGALG00000004644 Gallus gallus ENSGALG00000004644 I 0.368
Pvit_13286 Pogona vitticeps Pvit_13286 I 0.364
ENSMODG00000027338 Monodelphis domestica ENSMODG00000027338 I 0.357
ENSONIG00000001677 Oreochromis niloticus ENSONIG00000001677 I 0.356
ENSLOCG00000017255 Lepisosteus oculatus ENSLOCG00000017255 I 0.356
FOMPIDRAFT_1100359 Fomitopsis pinicola FOMPIDRAFT_1100359 I 0.355
ENSLACG00000002436 Latimeria chalumnae ENSLACG00000002436 I 0.354
hsf2 Oryzias latipes ENSORLG00000015498 I 0.354
PHLGIDRAFT_68835 Phlebiopsis gigantea PHLGIDRAFT_68835 I 0.354
ENSAMXG00000017965 Astyanax mexicanus ENSAMXG00000017965 I 0.354
e_gw1.1.2474.1 Mucor circinelloides e_gw1.1.2474.1 I 0.352
hsf3 Xenopus tropicalis XB-GENE-1021762 I 0.352
e_gw1.6.1274.1 Mucor circinelloides e_gw1.6.1274.1 I 0.351
hsf2 Gasterosteus aculeatus ENSGACG00000004065 I 0.351
FIBRA_02011 Fibroporia radiculosa FIBRA_02011 I 0.351
ENSOANG00000008146 Ornithorhynchus anatinus ENSOANG00000008146 I 0.348
CNB00120 Cryptococcus neoformans CNB00120 I 0.348
RO3G_03272 Rhizopus oryzae RO3G_03272 I 0.347
HSF1 Anolis carolinensis ENSACAG00000012604 I 0.347
HSF1 Monodelphis domestica ENSMODG00000010663 I 0.347
hsf1 Gasterosteus aculeatus ENSGACG00000010434 I 0.346
Hsf2 Mus musculus ENSMUSG00000019878 D 0.346
ENSGMOG00000000596 Gadus morhua ENSGMOG00000000596 I 0.346
Hsf1 Mus musculus ENSMUSG00000022556 D 0.345
Hsf1 Rattus norvegicus ENSRNOG00000021732 I 0.345
HSF1 Pteropus vampyrus ENSPVAG00000009267 I 0.345
Hsf1 Dipodomys ordii ENSDORG00000002333 I 0.345
HSF1 Canis familiaris ENSCAFG00000001563 I 0.345
ENSMPUG00000006704 Mustela putorius furo ENSMPUG00000006704 I 0.345
ENSTSYG00000006467 Tarsius syrichta ENSTSYG00000006467 I 0.345
HSF1 Homo sapiens ENSG00000185122 D 0.345
HSF1 Loxodonta africana ENSLAFG00000021374 I 0.345
HSF1 Macaca mulatta ENSMMUG00000014728 I 0.345
ENSSTOG00000007173 Ictidomys tridecemlineatus ENSSTOG00000007173 I 0.345
HSF1 Felis catus ENSFCAG00000007722 I 0.345
ENSLACG00000013265 Latimeria chalumnae ENSLACG00000013265 I 0.345
ENSPPYG00000018969 Pongo abelii ENSPPYG00000018969 I 0.345
ENSMLUG00000029200 Myotis lucifugus ENSMLUG00000029200 I 0.345
ENSCSAG00000008638 Chlorocebus sabaeus ENSCSAG00000008638 I 0.345
HSF1 Cavia porcellus ENSCPOG00000019305 I 0.345
ENSMLUG00000002310 Myotis lucifugus ENSMLUG00000002310 I 0.345
ENSAMEG00000005847 Ailuropoda melanoleuca ENSAMEG00000005847 I 0.345
HSF1 Gorilla gorilla ENSGGOG00000013602 I 0.345
e_gw1.6.465.1 Phycomyces blakesleeanus e_gw1.6.465.1 I 0.345
ENSPANG00000005938 Papio anubis ENSPANG00000005938 I 0.345
hsf1 Takifugu rubripes ENSTRUG00000000233 I 0.344
HSF1 Procavia capensis ENSPCAG00000006962 I 0.344
hsf2 Danio rerio ENSDARG00000053097 D 0.343
HSF1 Dasypus novemcinctus ENSDNOG00000047071 I 0.343
HSF2 Echinops telfairi ENSETEG00000006154 I 0.342
Hsf2 Rattus norvegicus ENSRNOG00000000808 I 0.342
HSF2 Macaca mulatta ENSMMUG00000007910 I 0.341
ENSMICG00000006415 Microcebus murinus ENSMICG00000006415 I 0.341
HSF2 Myotis lucifugus ENSMLUG00000002355 I 0.341
ENSOARG00000008274 Ovis aries ENSOARG00000008274 I 0.341
HSF2 Procavia capensis ENSPCAG00000016109 I 0.341
ENSPANG00000022516 Papio anubis ENSPANG00000022516 I 0.341
ENSPPYG00000016976 Pongo abelii ENSPPYG00000016976 I 0.341
HSF2 Pan troglodytes ENSPTRG00000018561 I 0.341
ENSTBEG00000013569 Tupaia belangeri ENSTBEG00000013569 I 0.341
ENSONIG00000015330 Oreochromis niloticus ENSONIG00000015330 I 0.341
HSF1 Otolemur garnettii ENSOGAG00000028708 I 0.341
ENSNLEG00000013721 Nomascus leucogenys ENSNLEG00000013721 I 0.341
ENSOARG00000014186 Ovis aries ENSOARG00000014186 I 0.341
HSF2 Oryctolagus cuniculus ENSOCUG00000025991 I 0.341
HSF2 Otolemur garnettii ENSOGAG00000015721 I 0.341
ENSMPUG00000014453 Mustela putorius furo ENSMPUG00000014453 I 0.341
ENSP00000332698-D1 Bos grunniens ENSP00000332698-D1 I 0.341
HSF2 Cavia porcellus ENSCPOG00000007509 I 0.341
HSF2 Homo sapiens ENSG00000025156 D 0.341
HSF2 Dasypus novemcinctus ENSDNOG00000031260 I 0.341
hsf2.L Xenopus laevis XB-GENE-954983 I 0.341
ENSAMEG00000007373 Ailuropoda melanoleuca ENSAMEG00000007373 I 0.341
ENSCSAG00000016240 Chlorocebus sabaeus ENSCSAG00000016240 I 0.341
HSF2 Erinaceus europaeus ENSEEUG00000000435 I 0.341
ENSP00000357440-D1 Bos grunniens ENSP00000357440-D1 I 0.341
HDID_0000861201 Hymenolepis diminuta HDID_0000861201 I 0.341
HSF2 Bos taurus ENSBTAG00000012946 I 0.341
HSF1 Bos taurus ENSBTAG00000020751 I 0.341
HSF2 Gorilla gorilla ENSGGOG00000023192 I 0.341
HSF2 Loxodonta africana ENSLAFG00000006440 I 0.341
ENSCHOG00000010951 Choloepus hoffmanni ENSCHOG00000010951 I 0.341
HSF2 Callithrix jacchus ENSCJAG00000003956 I 0.341
HSF2 Anolis carolinensis ENSACAG00000001260 I 0.340
HSF1 Sus scrofa ENSSSCG00000005917 I 0.340
HSF1 Echinops telfairi ENSETEG00000002048 I 0.340
hsf1 Danio rerio ENSDARG00000008818 I 0.339
HSF1 Ochotona princeps ENSOPRG00000004863 I 0.339
ENSLOCG00000007411 Lepisosteus oculatus ENSLOCG00000007411 I 0.339
hsf1 Xenopus laevis XB-GENE-997145 I 0.339
XP_002942927 Xenopus tropicalis XP_002942927 I 0.339
PTTG_05194 Puccinia triticina PTTG_05194 I 0.339
SPPG_07283 Spizellomyces punctatus SPPG_07283 I 0.339
HSF1 Equus caballus ENSECAG00000000621 I 0.339
hsf1.S Xenopus laevis XB-GENE-997146 I 0.339
hsf1 Tetraodon nigroviridis ENSTNIG00000018157 I 0.339
Alligator_sinensis_CCG019450.1 Alligator sinensis Alligator_sinensis_CCG019450.1 I 0.338
Ogr00694 Ophisaurus gracilis Ogr00694 I 0.338
GMDG_04555 Pseudogymnoascus destructans GMDG_04555 I 0.338
HSF2 Monodelphis domestica ENSMODG00000017753 I 0.338
ENSSHAG00000013467 Sarcophilus harrisii ENSSHAG00000013467 I 0.338
V499_02686 Pseudogymnoascus pannorum V499_02686 I 0.338
RO3G_12112 Rhizopus oryzae RO3G_12112 I 0.337
HNAJ_0000846501 Hymenolepis nana HNAJ_0000846501 I 0.336
hsf1 Oryzias latipes ENSORLG00000001699 I 0.336
ENSXMAG00000001905 Xiphophorus maculatus ENSXMAG00000001905 I 0.336
HSF1 Callithrix jacchus ENSCJAG00000021431 I 0.336
Hsf2 Dipodomys ordii ENSDORG00000012571 I 0.336
Pvit_18730 Pogona vitticeps Pvit_18730 I 0.336
ENSLOCG00000014654 Lepisosteus oculatus ENSLOCG00000014654 I 0.336
HmN_000096600 Hymenolepis microstoma HmN_000096600 I 0.335
ENSAMXG00000012942 Astyanax mexicanus ENSAMXG00000012942 I 0.335
estExt_fgenesh2_pg.C_250112 Monosiga brevicollis estExt_fgenesh2_pg.C_250112 I 0.335
XP_002937261 Xenopus tropicalis XP_002937261 I 0.334
ENSGALG00000014870 Gallus gallus ENSGALG00000014870 I 0.334
XP_002937262 Xenopus tropicalis XP_002937262 I 0.334
SCLCIDRAFT_1218516 Scleroderma citrinum SCLCIDRAFT_1218516 I 0.333
ENSCSAG00000005351 Chlorocebus sabaeus ENSCSAG00000005351 I 0.332
GLYMA17G20070 Glycine max GLYMA17G20070 I 0.332
L804_06549 Cryptococcus gattii L804_06549 I 0.331
HSF4 Cavia porcellus ENSCPOG00000010834 I 0.330
ENSFALG00000011294 Ficedula albicollis ENSFALG00000011294 I 0.329
HSF2 Taeniopygia guttata ENSTGUG00000011838 I 0.329
ENSPFOG00000003038 Poecilia formosa ENSPFOG00000003038 I 0.329
EDP41992.1 Malassezia globosa EDP41992.1 I 0.329
ENSMLUG00000015849 Myotis lucifugus ENSMLUG00000015849 I 0.328
BN946_scf185014.g98 Trametes cinnabarina BN946_scf185014.g98 I 0.328
GLYMA11G06010 Glycine max GLYMA11G06010 I 0.327
PGTG_06588 Puccinia graminis PGTG_06588 I 0.327
ENSBTAP00000004568-D1 Bos grunniens ENSBTAP00000004568-D1 I 0.327
HSF4 Tursiops truncatus ENSTTRG00000010241 I 0.327
GLYMA01G39260 Glycine max GLYMA01G39260 I 0.327
Alligator_sinensis_CCG019449.2 Alligator sinensis Alligator_sinensis_CCG019449.2 I 0.327
ENSNLEG00000004338 Nomascus leucogenys ENSNLEG00000004338 I 0.327
HSF4 Macaca mulatta ENSMMUG00000005906 I 0.327
HSF4 Loxodonta africana ENSLAFG00000021984 I 0.327
ENSOARG00000002740 Ovis aries ENSOARG00000002740 I 0.327
HSF4 Oryctolagus cuniculus ENSOCUG00000010001 I 0.327
HSF4 Equus caballus ENSECAG00000016708 I 0.327
Hsf4 Mus musculus ENSMUSG00000033249 I 0.327
ENSCSAG00000003768 Chlorocebus sabaeus ENSCSAG00000003768 I 0.327
HSF4 Canis familiaris ENSCAFG00000020379 I 0.327
HSF4 Bos taurus ENSBTAG00000003514 I 0.327
ENSAMEG00000017238 Ailuropoda melanoleuca ENSAMEG00000017238 I 0.327
ENSMPUG00000005418 Mustela putorius furo ENSMPUG00000005418 I 0.327
HSF4 Otolemur garnettii ENSOGAG00000001391 I 0.327
HSF4 Pan troglodytes ENSPTRG00000034007 I 0.327
HSF4 Pteropus vampyrus ENSPVAG00000000402 I 0.327
ENSSTOG00000027009 Ictidomys tridecemlineatus ENSSTOG00000027009 I 0.327
HSF4 Sus scrofa ENSSSCG00000002792 I 0.327
ENSPPYG00000007441 Pongo abelii ENSPPYG00000007441 I 0.327
HSF4 Homo sapiens ENSG00000102878 D 0.327
HSF4 Gorilla gorilla ENSGGOG00000011899 I 0.327
ENSPANG00000005017 Papio anubis ENSPANG00000005017 I 0.327
CapteG130381 Capitella teleta CapteG130381 I 0.327
Hsf4 Dipodomys ordii ENSDORG00000015128 I 0.327
ENSLACG00000010304 Latimeria chalumnae ENSLACG00000010304 I 0.326
HSF4 Felis catus ENSFCAG00000014099 I 0.326
SAPIO_CDS6676 Scedosporium apiospermum SAPIO_CDS6676 I 0.326
PTSG_11973 Salpingoeca rosetta PTSG_11973 I 0.326
HSF4 Ochotona princeps ENSOPRG00000015074 I 0.326
POPTR_0006s11680 Populus trichocarpa POPTR_0006s11680 I 0.326
Traes_5BL_FCB1625F3 Triticum aestivum Traes_5BL_FCB1625F3 I 0.325
HSF4 Myotis lucifugus ENSMLUG00000011083 I 0.325
ENSOCUG00000022713 Oryctolagus cuniculus ENSOCUG00000022713 I 0.325
V565_116890 Rhizoctonia solani V565_116890 I 0.325
BBA_04597 Beauveria bassiana BBA_04597 I 0.324
DACRYDRAFT_70902 Dacryopinax sp DACRYDRAFT_70902 I 0.324
ZYRO0G08734g Zygosaccharomyces rouxii ZYRO0G08734g I 0.324
ACRE_024160 Acremonium chrysogenum ACRE_024160 I 0.323
DI09_328p10 Microsporidia sp DI09_328p10 N 0.323
DI09_52p190 Microsporidia sp DI09_52p190 N 0.323
HSF4 Dasypus novemcinctus ENSDNOG00000032363 I 0.322
SPU_013409 Strongylocentrotus purpuratus SPU_013409 I 0.322
estExt_fgeneshTM_pg.C_40576 Tremella mesenterica estExt_fgeneshTM_pg.C_40576 I 0.322
Hsf4 Rattus norvegicus ENSRNOG00000015253 I 0.321
cassava14443.m1 Manihot esculenta cassava14443.m1 I 0.321
HSF4 Procavia capensis ENSPCAG00000013012 I 0.320
BRADI3G42130 Brachypodium distachyon BRADI3G42130 I 0.320
CLUG_04646 Clavispora lusitaniae CLUG_04646 I 0.320
CLUG_04646 Candida lusitaniae CLUG_04646 I 0.320
hsf1 Schizosaccharomyces pombe SPAC2E12.02 I 0.320
SMAR008659 Strigamia maritima SMAR008659 I 0.320
Thhalv10013758m.g Eutrema salsugineum Thhalv10013758m.g I 0.319
SOCG_00564 Schizosaccharomyces octosporus SOCG_00564 I 0.319
SPOG_01941 Schizosaccharomyces cryophilus SPOG_01941 I 0.319
GLOINDRAFT_240353 Rhizophagus irregularis GLOINDRAFT_240353 I 0.319