Setdb1 (Rattus norvegicus)
MBD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01429 (MBD) IPR001739 ENSRNOG00000021143 T260408_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA binding activity; histone methyltransferase activity (H3-K9 specific); and promoter-specific chromatin binding activity. Involved in response to ethanol and response to vitamin. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder and lung cancer. Orthologous to human SETDB1 (SET domain bifurcated histone lysine methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SETDB1
M11031_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SETDB1_01 		0.987 0.987
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000028709 MBD 606 680
ENSRNOP00000073356 MBD 626 700

Links

Other MBD family TFs
Other Rattus norvegicus TFs

66 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SETDB1 Ochotona princeps ENSOPRG00000015349 I 0.987
ENSPANG00000020214 Papio anubis ENSPANG00000020214 I 0.987
SETDB1 Procavia capensis ENSPCAG00000002527 I 0.987
SETDB1 Otolemur garnettii ENSOGAG00000010320 I 0.987
SETDB1 Oryctolagus cuniculus ENSOCUG00000003642 I 0.987
SETDB1 Macaca mulatta ENSMMUG00000023235 I 0.987
ENSMPUG00000004298 Mustela putorius furo ENSMPUG00000004298 I 0.987
Setdb1 Mus musculus ENSMUSG00000015697 I 0.987
ENSAMEG00000001160 Ailuropoda melanoleuca ENSAMEG00000001160 I 0.987
ENSPPYG00000000887 Pongo abelii ENSPPYG00000000887 I 0.987
SETDB1 Pan troglodytes ENSPTRG00000001267 I 0.987
SETDB1 Vicugna pacos ENSVPAG00000005440 I 0.987
ENSBTAP00000000107-D1 Bos grunniens ENSBTAP00000000107-D1 I 0.987
ENSP00000357965 Macaca fascicularis ENSP00000357965 I 0.987
SETDB1 Tursiops truncatus ENSTTRG00000006966 I 0.987
SETDB1 Tupaia belangeri ENSTBEG00000009306 I 0.987
SETDB1 Pteropus vampyrus ENSPVAG00000004355 I 0.987
SETDB1 Sus scrofa ENSSSCG00000006645 I 0.987
ENSSTOG00000006770 Ictidomys tridecemlineatus ENSSTOG00000006770 I 0.987
SETDB1 Loxodonta africana ENSLAFG00000004006 I 0.987
ENSOARG00000020880 Ovis aries ENSOARG00000020880 I 0.987
SETDB1 Homo sapiens ENSG00000143379 D 0.987
SETDB1 Cavia porcellus ENSCPOG00000001632 I 0.987
SETDB1 Callithrix jacchus ENSCJAG00000006972 I 0.987
SETDB1 Choloepus hoffmanni ENSCHOG00000004013 I 0.987
ENSCSAG00000018034 Chlorocebus sabaeus ENSCSAG00000018034 I 0.987
SETDB1 Felis catus ENSFCAG00000009655 I 0.987
SETDB1 Equus caballus ENSECAG00000023954 I 0.987
SETDB1 Dasypus novemcinctus ENSDNOG00000007754 I 0.987
SETDB1 Erinaceus europaeus ENSEEUG00000015825 I 0.987
Setdb1 Dipodomys ordii ENSDORG00000006830 I 0.987
SETDB1 Canis familiaris ENSCAFG00000023501 I 0.987
SETDB1 Gorilla gorilla ENSGGOG00000016308 I 0.987
SETDB1 Bos taurus ENSBTAG00000000098 I 0.987
Myotis_brandtii_SETDB1_10031834 Myotis brandtii Myotis_brandtii_SETDB1_10031834 I 0.973
SETDB1 Myotis lucifugus ENSMLUG00000010486 I 0.973
SETDB1 Monodelphis domestica ENSMODG00000018821 I 0.960
ENSMEUG00000006544 Macropus eugenii ENSMEUG00000006544 I 0.960
ENSSHAG00000012701 Sarcophilus harrisii ENSSHAG00000012701 I 0.960
ENSAPLG00000013908 Anas platyrhynchos ENSAPLG00000013908 I 0.947
Cmyd_10007606 Chelonia mydas Cmyd_10007606 I 0.933
Alligator_sinensis_CCG020665.1 Alligator sinensis Alligator_sinensis_CCG020665.1 I 0.920
ENSPSIG00000008407 Pelodiscus sinensis ENSPSIG00000008407 I 0.920
SETDB1 Meleagris gallopavo ENSMGAG00000001018 I 0.920
ENSGALG00000029138 Gallus gallus ENSGALG00000029138 I 0.920
SETDB1 Gallus gallus ENSGALG00000024051 I 0.920
ENSLACG00000011159 Latimeria chalumnae ENSLACG00000011159 I 0.907
Pvit_04977 Pogona vitticeps Pvit_04977 I 0.893
SETDB1 Taeniopygia guttata ENSTGUG00000004684 I 0.893
setdb1.L Xenopus laevis XB-GENE-866480 I 0.893
XP_002935516 Xenopus tropicalis XP_002935516 I 0.893
XP_002935515 Xenopus tropicalis XP_002935515 I 0.893
ENSMEUG00000000555 Macropus eugenii ENSMEUG00000000555 I 0.880
ENSNLEG00000009996 Nomascus leucogenys ENSNLEG00000009996 I 0.878
setdb1b Gasterosteus aculeatus ENSGACG00000011675 I 0.827
ENSPFOG00000004623 Poecilia formosa ENSPFOG00000004623 I 0.813
ENSGMOG00000005993 Gadus morhua ENSGMOG00000005993 I 0.813
ENSXMAG00000016600 Xiphophorus maculatus ENSXMAG00000016600 I 0.813
ENSONIG00000006454 Oreochromis niloticus ENSONIG00000006454 I 0.813
setdb1b Oryzias latipes ENSORLG00000010602 I 0.813
ENSPFOG00000004429 Poecilia formosa ENSPFOG00000004429 I 0.813
setdb1b Takifugu rubripes ENSTRUG00000014641 I 0.813
setdb1b Tetraodon nigroviridis ENSTNIG00000008065 I 0.787
setdb1b Danio rerio ENSDARG00000099021 I 0.787
SETDB1 Microcebus murinus ENSMICG00000000425 I 0.761