ENSP00000156825 (Macaca fascicularis)
MBD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF01429 (MBD) IPR001739 ENSP00000156825 T261264_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000156825 MBD 28 77
ENSP00000156825 MBD 77 151

Links

Other MBD family TFs
Other Macaca fascicularis TFs

35 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSAMEG00000003491 Ailuropoda melanoleuca ENSAMEG00000003491 I 0.936
Alligator_sinensis_CCG000430.1 Alligator sinensis Alligator_sinensis_CCG000430.1 N 0.763
ENSAPLG00000003384 Anas platyrhynchos ENSAPLG00000003384 N 0.841
Afo_R010057 Aptenodytes forsteri Afo_R010057 N 0.830
ENSAMXG00000017952 Astyanax mexicanus ENSAMXG00000017952 I 0.922
ENSBTAP00000003926-D1 Bos grunniens ENSBTAP00000003926-D1 N 0.761
Brh_R003386 Buceros rhinoceros Brh_R003386 N 0.830
Aan_R011698 Calypte anna Aan_R011698 N 0.783
MBD3 Canis familiaris ENSCAFG00000019503 N 0.910
mbd3a Danio rerio ENSDARG00000061774 I 0.883
mbd3b Danio rerio ENSDARG00000042029 I 0.784
MBD3 Equus caballus ENSECAG00000015485 I 0.952
MBD3 Felis catus ENSFCAG00000000763 I 0.830
ENSGMOG00000008953 Gadus morhua ENSGMOG00000008953 I 0.824
MBD3 Gasterosteus aculeatus ENSGACG00000012755 I 0.893
Gfo_R007597 Geospiza fortis Gfo_R007597 N 0.783
MBD3 Homo sapiens ENSG00000071655 N 0.977
ENSLOCG00000006043 Lepisosteus oculatus ENSLOCG00000006043 N 0.795
MBD3 Meleagris gallopavo ENSMGAG00000002493 N 0.841
MBD3 Monodelphis domestica ENSMODG00000004125 N 0.841
ENSMPUG00000008045 Mustela putorius furo ENSMPUG00000008045 N 0.899
Mbd3 Mus musculus ENSMUSG00000035478 N 0.932
Myotis_brandtii_MBD3_10015627 Myotis brandtii Myotis_brandtii_MBD3_10015627 N 0.879
MBD3 Ochotona princeps ENSOPRG00000008719 I 0.920
MBD3 Ornithorhynchus anatinus ENSOANG00000003672 N 0.725
ENSOARG00000012359 Ovis aries ENSOARG00000012359 I 0.841
ENSPANG00000015324 Papio anubis ENSPANG00000015324 N 0.977
ENSPPYG00000009325 Pongo abelii ENSPPYG00000009325 I 0.953
Mbd3 Rattus norvegicus ENSRNOG00000028956 N 0.932
ENSSHAG00000013346 Sarcophilus harrisii ENSSHAG00000013346 N 0.841
MBD3 Sus scrofa ENSSSCG00000013435 N 0.730
MBD3 Tetraodon nigroviridis ENSTNIG00000010627 N 0.773
Tal_R008196 Tyto alba Tal_R008196 N 0.830
mbd3.S Xenopus laevis XB-GENE-491557 I 0.875
ENSXMAG00000012716 Xiphophorus maculatus ENSXMAG00000012716 I 0.833