TERF2 (Homo sapiens)
Myb/SANT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00249 (Myb_DNA-binding) IPR014778 ENSG00000132604 T269579_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Terf2
M02323_2.00
Mus musculus
NAACCCTAV

BTAGGGTTN
PBM
Weirauch et al.(2014)
pTH7805
0.857 0.915
For this family, TFs with SR scores > 0.661 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000254942 Myb 489 537

Links

Other Myb/SANT family TFs
Other Homo sapiens TFs

54 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSOARG00000003567 Ovis aries ENSOARG00000003567 I 0.909
ENSNLEG00000005506 Nomascus leucogenys ENSNLEG00000005506 I 0.909
ENSMPUG00000007352 Mustela putorius furo ENSMPUG00000007352 I 0.909
TERF2 Macaca mulatta ENSMMUG00000016633 I 0.909
ENSPANG00000018001 Papio anubis ENSPANG00000018001 I 0.909
TERF2 Pan troglodytes ENSPTRG00000008281 I 0.909
ENSP00000254942 Macaca fascicularis ENSP00000254942 I 0.909
ENSBTAP00000010016-D1 Bos grunniens ENSBTAP00000010016-D1 I 0.909
TERF2 Tursiops truncatus ENSTTRG00000010015 I 0.909
TERF2 Sus scrofa ENSSSCG00000002762 I 0.909
TERF2 Gorilla gorilla ENSGGOG00000004372 I 0.909
TERF2 Oryctolagus cuniculus ENSOCUG00000017662 I 0.909
TERF2 Bos taurus ENSBTAG00000007617 I 0.909
ENSCSAG00000004144 Chlorocebus sabaeus ENSCSAG00000004144 I 0.909
TERF2 Callithrix jacchus ENSCJAG00000015339 I 0.909
TERF2 Choloepus hoffmanni ENSCHOG00000010819 I 0.909
TERF2 Canis familiaris ENSCAFG00000020267 I 0.909
TERF2 Dasypus novemcinctus ENSDNOG00000014627 I 0.909
ENSAMEG00000007513 Ailuropoda melanoleuca ENSAMEG00000007513 I 0.909
TERF2 Equus caballus ENSECAG00000024534 I 0.909
Terf2 Dipodomys ordii ENSDORG00000011208 I 0.901
TERF2 Vicugna pacos ENSVPAG00000003993 I 0.901
Myotis_brandtii_TERF2_10022452 Myotis brandtii Myotis_brandtii_TERF2_10022452 I 0.901
TERF2 Procavia capensis ENSPCAG00000006534 I 0.901
TERF2 Myotis lucifugus ENSMLUG00000006584 I 0.901
TERF2 Ochotona princeps ENSOPRG00000006995 I 0.896
TERF2 Tupaia belangeri ENSTBEG00000011528 I 0.896
TERF2 Pteropus vampyrus ENSPVAG00000015982 I 0.896
TERF2 Cavia porcellus ENSCPOG00000003717 I 0.896
TERF2 Monodelphis domestica ENSMODG00000002766 I 0.891
ENSSHAG00000013733 Sarcophilus harrisii ENSSHAG00000013733 I 0.891
ENSFCAG00000013579 Felis catus ENSFCAG00000013579 I 0.888
ENSSTOG00000012882 Ictidomys tridecemlineatus ENSSTOG00000012882 I 0.888
ENSTSYG00000008563 Tarsius syrichta ENSTSYG00000008563 I 0.882
TERF2 Otolemur garnettii ENSOGAG00000008071 I 0.881
TERF2 Echinops telfairi ENSETEG00000013553 I 0.875
Terf2 Mus musculus ENSMUSG00000031921 D 0.857
Terf2 Rattus norvegicus ENSRNOG00000020435 I 0.843
TERF2 Ornithorhynchus anatinus ENSOANG00000002365 I 0.833
ENSPPYG00000007505 Pongo abelii ENSPPYG00000007505 I 0.820
ENSLOCG00000001317 Lepisosteus oculatus ENSLOCG00000001317 I 0.775
terf2.L Xenopus laevis XB-GENE-990302 I 0.769
ENSPSIG00000011530 Pelodiscus sinensis ENSPSIG00000011530 I 0.764
terf2 Xenopus tropicalis XB-GENE-990299 I 0.763
Alligator_sinensis_CCG009030.1 Alligator sinensis Alligator_sinensis_CCG009030.1 I 0.733
Pvit_16279 Pogona vitticeps Pvit_16279 I 0.723
ENSTGUG00000008090 Taeniopygia guttata ENSTGUG00000008090 I 0.722
ENSACAG00000003497 Anolis carolinensis ENSACAG00000003497 I 0.722
Tal_R010022 Tyto alba Tal_R010022 I 0.700
Afo_R007440 Aptenodytes forsteri Afo_R007440 I 0.700
Aan_R009163 Calypte anna Aan_R009163 I 0.691
ENSFALG00000002781 Ficedula albicollis ENSFALG00000002781 I 0.675
ENSAPLG00000007421 Anas platyrhynchos ENSAPLG00000007421 I 0.673
ENSLACG00000005641 Latimeria chalumnae ENSLACG00000005641 N 0.661