stc (Drosophila melanogaster)
NFX

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01422 (zf-NF-X1) IPR000967 FBgn0001978 T300576_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; ubiquitin protein ligase activity; and zinc ion binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and protein autoubiquitination. Located in nucleus. Is expressed in several structures, including embryonic/larval brain; germline cell; ovary; and presumptive embryonic/larval central nervous system. Orthologous to human NFX1 (nuclear transcription factor, X-box binding 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
stc
M03922_2.00
Drosophila melanogaster
YATYACMWKGTRATA

TATYACMWKGTRATR
SELEX
Nitta et al.(2015)
stc_1
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0080265 NFX 474 491
FBpp0080265 NFX 527 545
FBpp0080265 NFX 585 603
FBpp0080265 NFX 644 666
FBpp0080265 NFX 733 751
FBpp0080265 NFX 844 869
FBpp0080265 NFX 876 895
FBpp0080266 NFX 467 484
FBpp0080266 NFX 520 538
FBpp0080266 NFX 578 596
FBpp0080266 NFX 637 659
FBpp0080266 NFX 726 744
FBpp0080266 NFX 837 862
FBpp0080266 NFX 869 888
FBpp0304749 NFX 463 480
FBpp0304749 NFX 516 534
FBpp0304749 NFX 574 592
FBpp0304749 NFX 633 655
FBpp0304749 NFX 722 740
FBpp0304749 NFX 833 858
FBpp0304749 NFX 865 884
FBpp0304750 NFX 470 487
FBpp0304750 NFX 523 541
FBpp0304750 NFX 581 599
FBpp0304750 NFX 640 662
FBpp0304750 NFX 729 747
FBpp0304750 NFX 840 865
FBpp0304750 NFX 872 891

Links

Other NFX family TFs
Other Drosophila melanogaster TFs

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13 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action