nhr-6 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00003605 T306130_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
nhr-6
M01298_2.00
Caenorhabditis elegans
AAAKGTCA

TGACMTTT
PBM
Lambert et al.(2019)
pTH9944
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Nr4a2
M00818_2.00
Mus musculus
AAAGGTCA

TGACCTTT
PBM
Weirauch et al.(2013)
pTH3467
0.955 0.757
NR4A2
M03383_2.00
Homo sapiens
AGGTCAHNNNDTGACCT

AGGTCAHNNNDTGACCT
SELEX
Jolma et al.(2013)
NR4A2_1
0.955 0.757
NR4A2
M03384_2.00
Homo sapiens
TGACCTTTAAAGGTCA

TGACCTTTAAAGGTCA
SELEX
Jolma et al.(2013)
NR4A2_2
0.955 0.757
NR4A2
M03385_2.00
Homo sapiens
NBTAAAGGTCA

TGACCTTTAVN
SELEX
Jolma et al.(2013)
NR4A2_3
0.955 0.757
NR4A2
M05639_2.00
Homo sapiens
NWAAKGTCAN

NTGACMTTWN
SELEX
Yin et al.(2017)
NR4A2_eDBD_HT-SELEX
0.955 0.757
NR4A2
M05881_2.00
Homo sapiens
NAAAKGTYA

TRACMTTTN
SMiLE-seq
Isakova et al.(2017)
NR4A2
0.955 0.757
NR4A2
M09286_2.00
Homo sapiens
RAAGGTCAV

BTGACCTTY
Misc
Kulakovskiy et al.(2013)
NR4A2_HUMAN.H11MO.0.C
0.955 0.757
Nr4a2
M09323_2.00
Mus musculus
RAAGGTCAV

BTGACCTTY
Misc
Kulakovskiy et al.(2013)
NR4A2_MOUSE.H11MO.0.C
0.955 0.757
NR4A2
M11151_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NURR1_Q3_01
0.955 0.757
NR4A2
M11152_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NURR1_Q3
0.955 0.757
NR4A2
M08461_2.00
Homo sapiens
RAGGTCAM

KTGACCTY
COMPILED
Mathelier et al.(2014)
MA0160.1
0.955 0.757
NR4A2
M05640_2.00
Homo sapiens
NAAAGGTCRN

NYGACCTTTN
SELEX
Yin et al.(2017)
NR4A2_eDBD_Methyl-HT-SELEX
0.955 0.757
Hr38
M03939_2.00
Drosophila melanogaster
NAAAGGTCA

TGACCTTTN
SELEX
Nitta et al.(2015)
Hr38_1
0.943 0.729
NR4A1
M05601_2.00
Homo sapiens
NAAAGGTCAN

NTGACCTTTN
SELEX
Yin et al.(2017)
NR4A1_eDBD_HT-SELEX_1
0.920 0.743
NR4A1
M05602_2.00
Homo sapiens
NAAAGGTCAN

NTGACCTTTN
SELEX
Yin et al.(2017)
NR4A1_eDBD_HT-SELEX_2
0.920 0.743
NR4A1
M08153_2.00
Homo sapiens
NAAAGGTCAN

NTGACCTTTN
ChIP-seq
Mathelier et al.(2014)
MA1112.1
0.920 0.743
NR4A1
M09274_2.00
Homo sapiens
AAAKGBCAN

NTGVCMTTT
Misc
Kulakovskiy et al.(2013)
NR4A1_HUMAN.H11MO.0.A
0.920 0.743
NR4A1
M09608_2.00
Homo sapiens
NNDNAAAGGTCA

TGACCTTTNHNN
Misc
Heinz et al.(2010)
K562-NR4A1_GSE31363
0.920 0.743
NR4A1
M11132_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NUR77_Q5_01
0.920 0.743
NR4A1
M11133_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NUR77_Q5_02
0.920 0.743
NR4A1
M11134_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NUR77_Q5
0.920 0.743
NR4A1
M05603_2.00
Homo sapiens
NAAAGGTCRN

NYGACCTTTN
SELEX
Yin et al.(2017)
NR4A1_eDBD_Methyl-HT-SELEX_1
0.920 0.743
NR4A1
M05604_2.00
Homo sapiens
NAAAGGTCRN

NYGACCTTTN
SELEX
Yin et al.(2017)
NR4A1_eDBD_Methyl-HT-SELEX_2
0.920 0.743
Nr4a1
M09317_2.00
Mus musculus
NRAADGKCA

TGMCHTTYN
Misc
Kulakovskiy et al.(2013)
NR4A1_MOUSE.H11MO.0.B
0.920 0.729
Q95WG3_ACRMI
M02424_2.00
Acropora millepora
NRAGGTCAN

NTGACCTYN
PBM
Weirauch et al.(2014)
pTH6144
0.887 0.600
Hr4
M06435_2.00
Drosophila melanogaster
AAGGTCA

TGACCTT
B1H
Zhu et al.(2011)
Hr4_SANGER_5_FBgn0023546
0.854 0.600
Rxra
M00181_2.00
Mus musculus
NRRGGTCANN

NNTGACCYYN
PBM
Badis et al.(2009)
Rxra_1035
0.851 0.643
RXRA
M03408_2.00
Homo sapiens
RRGGTCAAAGGTCA

TGACCTTTGACCYY
SELEX
Jolma et al.(2013)
RXRA_1
0.851 0.643
RXRA
M03409_2.00
Homo sapiens
RRGGTCATGACCYY

RRGGTCATGACCYY
SELEX
Jolma et al.(2013)
RXRA_2
0.851 0.643
RXRA
M03410_2.00
Homo sapiens
RRGGTCAAAGGTCA

TGACCTTTGACCYY
SELEX
Jolma et al.(2013)
RXRA_3
0.851 0.643
RXRA
M03411_2.00
Homo sapiens
RRGGTCATGACCYY

RRGGTCATGACCYY
SELEX
Jolma et al.(2013)
RXRA_4
0.851 0.643
Rxra
M03421_2.00
Mus musculus
RRGGTCAAAGGTCA

TGACCTTTGACCYY
SELEX
Jolma et al.(2013)
Rxra_1
0.851 0.643
Rxra
M03422_2.00
Mus musculus
RGGTCATGACCY

RGGTCATGACCY
SELEX
Jolma et al.(2013)
Rxra_2
0.851 0.643
RXRA
M05671_2.00
Homo sapiens
RRGGTCAAAGGTCAN

NTGACCTTTGACCYY
SELEX
Yin et al.(2017)
RXRA_eDBD_HT-SELEX
0.851 0.643
RXRA
M05882_2.00
Homo sapiens
VRGKTBAAAGGTYRH

DYRACCTTTVAMCYB
SMiLE-seq
Isakova et al.(2017)
RXRa
0.851 0.643
RXRA
M07993_2.00
Homo sapiens
NRRGGTCA

TGACCYYN
ChIP-seq
Gerstein et al.(2012)
H1-hESC_RXRA_HudsonAlpha
0.851 0.643
RXRA
M07994_2.00
Homo sapiens
DDNNMRRGGTCANDN

NHNTGACCYYKNNHH
ChIP-seq
Gerstein et al.(2012)
HepG2_RXRA_HudsonAlpha
0.851 0.643
RXRA
M09294_2.00
Homo sapiens
VDDDNDNNVRRRGGKCAVDV

BHBTGMCCYYYBNNHNHHHB
Misc
Kulakovskiy et al.(2013)
RXRA_HUMAN.H11MO.0.A
0.851 0.643
Rxra
M09306_2.00
Mus musculus
DDVNNNNNRAGKTCAAGGYCA

TGRCCTTGAMCTYNNNNNBHH
Misc
Kulakovskiy et al.(2013)
RXRA_MOUSE.H11MO.0.A
0.851 0.643
RXRA
M11182_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$RXRA_07
0.851 0.643
RXRA
M05672_2.00
Homo sapiens
RRGGTCAAAGGTCAH

DTGACCTTTGACCYY
SELEX
Yin et al.(2017)
RXRA_eDBD_Methyl-HT-SELEX
0.851 0.643
Rxrb
M02402_2.00
Mus musculus
VRGGTCAH

DTGACCYB
PBM
Weirauch et al.(2014)
pTH2861
0.847 0.600
RXRB
M03415_2.00
Homo sapiens
RRGGTCAAAGGTCA

TGACCTTTGACCYY
SELEX
Jolma et al.(2013)
RXRB_1
0.847 0.600
Rxrb
M03435_2.00
Mus musculus
GRGGTCAAAGGTCA

TGACCTTTGACCYC
SELEX
Jolma et al.(2013)
Rxrb_1
0.847 0.600
RXRB
M05681_2.00
Homo sapiens
RRGGTCAAAGGTCAN

NTGACCTTTGACCYY
SELEX
Yin et al.(2017)
RXRB_eDBD_HT-SELEX_1
0.847 0.600
RXRB
M05682_2.00
Homo sapiens
RRGGTCAYGACCYY

RRGGTCRTGACCYY
SELEX
Yin et al.(2017)
RXRB_eDBD_HT-SELEX_2
0.847 0.600
RXRB
M09297_2.00
Homo sapiens
DSAGGTCASD

HSTGACCTSH
Misc
Kulakovskiy et al.(2013)
RXRB_HUMAN.H11MO.0.C
0.847 0.600
Rxrb
M09330_2.00
Mus musculus
DSAGGTCASD

HSTGACCTSH
Misc
Kulakovskiy et al.(2013)
RXRB_MOUSE.H11MO.0.C
0.847 0.600
RXRB
M05683_2.00
Homo sapiens
RRGGTCAAAGGTCRN

NYGACCTTTGACCYY
SELEX
Yin et al.(2017)
RXRB_eDBD_Methyl-HT-SELEX_1
0.847 0.600
RXRB
M05684_2.00
Homo sapiens
RRGGTCRYGACCYY

RRGGTCRYGACCYY
SELEX
Yin et al.(2017)
RXRB_eDBD_Methyl-HT-SELEX_2
0.847 0.600
Rxrg
M02400_2.00
Mus musculus
VRGGTCAN

NTGACCYB
PBM
Weirauch et al.(2014)
pTH2880
0.846 0.629
RXRG
M03375_2.00
Homo sapiens
RRGGTCAAAGGTCA

TGACCTTTGACCYY
SELEX
Jolma et al.(2013)
RXRG_1
0.846 0.629
RXRG
M03376_2.00
Homo sapiens
RRGGTCATGACCYY

RRGGTCATGACCYY
SELEX
Jolma et al.(2013)
RXRG_2
0.846 0.629
RXRG
M03377_2.00
Homo sapiens
GRGGTCAAAGGTCA

TGACCTTTGACCYC
SELEX
Jolma et al.(2013)
RXRG_3
0.846 0.629
RXRG
M03378_2.00
Homo sapiens
NRGGTCATGACCYC

GRGGTCATGACCYN
SELEX
Jolma et al.(2013)
RXRG_4
0.846 0.629
RXRG
M02746_2.00
Homo sapiens
GGTCAAAGGTCA

TGACCTTTGACC
SELEX
Jolma et al.(2010)
RXRG_dimer
0.846 0.629
RXRG
M05615_2.00
Homo sapiens
VRGGTCAAAGGTCAN

NTGACCTTTGACCYB
SELEX
Yin et al.(2017)
RXRG_FL_HT-SELEX_1
0.846 0.629
RXRG
M05616_2.00
Homo sapiens
RRGGTCAYGACCYY

RRGGTCRTGACCYY
SELEX
Yin et al.(2017)
RXRG_FL_HT-SELEX_2
0.846 0.629
RXRG
M05879_2.00
Homo sapiens
RGGTBAARGGTBRND

HNYVACCYTTVACCY
SMiLE-seq
Isakova et al.(2017)
RXRg
0.846 0.629
RXRG
M09280_2.00
Homo sapiens
NGTCAAAGGTCAH

DTGACCTTTGACN
Misc
Kulakovskiy et al.(2013)
RXRG_HUMAN.H11MO.0.B
0.846 0.629
Rxrg
M09305_2.00
Mus musculus
VDDVDNSVNRAGKTCAAGGYCA

TGRCCTTGAMCTYNBSNHBHHB
Misc
Kulakovskiy et al.(2013)
RXRG_MOUSE.H11MO.0.B
0.846 0.629
RXRG
M05617_2.00
Homo sapiens
DRGGTBAARGGTBRN

NYVACCYTTVACCYH
SELEX
Yin et al.(2017)
RXRG_FL_Methyl-HT-SELEX_1
0.846 0.629
RXRG
M05618_2.00
Homo sapiens
VRGGTCAYGACCYB

VRGGTCRTGACCYB
SELEX
Yin et al.(2017)
RXRG_FL_Methyl-HT-SELEX_2
0.846 0.629
usp
M03934_2.00
Drosophila melanogaster
ARRGGTCAAAGGTCA

TGACCTTTGACCYYT
SELEX
Nitta et al.(2015)
usp_1
0.838 0.614
usp
M06426_2.00
Drosophila melanogaster
HRRGGTCAH

DTGACCYYD
B1H
Zhu et al.(2011)
usp_SANGER_5_FBgn0003964
0.838 0.614
usp
M02709_2.00
Drosophila melanogaster
GGGGTCACSN

NSGTGACCCC
SELEX
Mathelier et al.(2014)
MA0016.1
0.838 0.614
usp
M09689_2.00
Drosophila melanogaster
KRGGTCACG

CGTGACCYM
Misc
Kulakovskiy et al.(2009)
usp
0.838 0.614
usp
M11191_2.00
Drosophila melanogaster
GRGGTCAYS

SRTGACCYC
Transfac
Matys et al.(2006)
I$CF1_01
0.838 0.614
usp
M11192_2.00
Drosophila melanogaster
GGGGTCAYS

SRTGACCCC
Transfac
Matys et al.(2006)
I$CF1_02
0.838 0.614
Nr2f6
M00811_2.00
Mus musculus
NRRGGTCANN

NNTGACCYYN
PBM
Weirauch et al.(2013)
pTH2193
0.749 0.543
Nr2f6
M03419_2.00
Mus musculus
RAGGTCAADAGGTCA

TGACCTHTTGACCTY
SELEX
Jolma et al.(2013)
Nr2f6_1
0.749 0.543
Nr2f6
M03420_2.00
Mus musculus
RRGGTCAAAGGTCA

TGACCTTTGACCYY
SELEX
Jolma et al.(2013)
Nr2f6_2
0.749 0.543
For this family, TFs with SR scores > 0.745 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01298_2.00 Nuclear receptor 51 120

DNA Binding Domains

Protein ID Domain From To Sequence
C48D5.1a Nuclear receptor 266 335
C48D5.1b.1 Nuclear receptor 130 199
C48D5.1b.2 Nuclear receptor 130 199

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

731 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
HY5 Arabidopsis thaliana AT5G11260 D 0.000
Q39895_SOYBN Glycine max Q39895_SOYBN D 0.000
Cucsa.162360 Cucumis sativus Cucsa.162360 I 0.000
Cucsa.310450 Cucumis sativus Cucsa.310450 I 0.000
e_gw1.80.85.1 Physcomitrella patens e_gw1.80.85.1 I 0.000
mgf012104m Mimulus guttatus mgf012104m I 0.000
mgf014305m Mimulus guttatus mgf014305m I 0.000
SAR_estExt_Genewise1Plus.C_20674 Micromonas pusilla SAR_estExt_Genewise1Plus.C_20674 I 0.000
Aquca_001_00822 Aquilegia coerulea Aquca_001_00822 I 0.000
Bostr.23997s0021 Boechera stricta Bostr.23997s0021 I 0.000
Bostr.29827s0269 Boechera stricta Bostr.29827s0269 I 0.000
cassava8163.valid.m1 Manihot esculenta cassava8163.valid.m1 I 0.000
29848.m004650 Ricinus communis 29848.m004650 I 0.000
Cla022656 Citrullus lanatus Cla022656 I 0.000
Solyc08g061130.2 Solanum lycopersicum Solyc08g061130.2 I 0.000
TCM_038392 Theobroma cacao TCM_038392 I 0.000
Traes_6AS_AFF47E71C Triticum aestivum Traes_6AS_AFF47E71C I 0.000
Traes_6BS_993CBD840 Triticum aestivum Traes_6BS_993CBD840 I 0.000
Traes_7DL_68B814464 Triticum aestivum Traes_7DL_68B814464 I 0.000
TRIUR3_25965 Triticum urartu TRIUR3_25965 I 0.000
HY5 Vitis vinifera VIT_04s0008g05210 I 0.000
Ca_21380 Cicer arietinum Ca_21380 I 0.000
Cla021273 Citrullus lanatus Cla021273 I 0.000
Cagra.7526s0027 Capsella grandiflora Cagra.7526s0027 I 0.000
Carubv10003520m.g Capsella rubella Carubv10003520m.g I 0.000
Pavir.Da00549 Panicum virgatum Pavir.Da00549 I 0.000
Pavir.Db01231 Panicum virgatum Pavir.Db01231 I 0.000
SapurV1A.0043s0530 Salix purpurea SapurV1A.0043s0530 I 0.000
SapurV1A.0073s0400 Salix purpurea SapurV1A.0073s0400 I 0.000
SapurV1A.3812s0010 Salix purpurea SapurV1A.3812s0010 I 0.000
Thhalv10004860m.g Eutrema salsugineum Thhalv10004860m.g I 0.000
Thhalv10014851m.g Eutrema salsugineum Thhalv10014851m.g I 0.000
PK17235.1 Cannabis sativa PK17235.1 I 0.000
chr6.LjT14A08.90.nd Lotus japonicus chr6.LjT14A08.90.nd I 0.000
Pavir.Aa02966 Panicum virgatum Pavir.Aa02966 I 0.000
orange1.1g030957m.g Citrus sinensis orange1.1g030957m.g I 0.000
MDP0000586302 Malus domestica MDP0000586302 I 0.000
Ciclev10009720m.g Citrus clementina Ciclev10009720m.g I 0.000
Eucgr.C02802 Eucalyptus grandis Eucgr.C02802 I 0.000
EuGene.0200010492 Micromonas sp RCC299 EuGene.0200010492 I 0.000
evm.TU.supercontig_115.9 Carica papaya evm.TU.supercontig_115.9 I 0.000
gene11666-v1.0-hybrid Fragaria vesca gene11666-v1.0-hybrid I 0.000
Gorai.004G274100 Gossypium raimondii Gorai.004G274100 I 0.000
Lus10002028.g Linum usitatissimum Lus10002028.g I 0.000
Lus10002900.g Linum usitatissimum Lus10002900.g I 0.000
MDP0000264514 Malus domestica MDP0000264514 I 0.000
LjB12O06.40.nc Lotus japonicus LjB12O06.40.nc I 0.000
Si018524m.g Setaria italica Si018524m.g I 0.000
BGIOSGA002286 Oryza indica BGIOSGA002286 I 0.000
GRMZM2G137046 Zea mays GRMZM2G137046 I 0.000
GRMZM2G140355 Zea mays GRMZM2G140355 I 0.000
GSMUA_Achr10G27050_001 Musa acuminata GSMUA_Achr10G27050_001 I 0.000
GSMUA_Achr5G06060_001 Musa acuminata GSMUA_Achr5G06060_001 I 0.000
GSMUA_Achr6G05280_001 Musa acuminata GSMUA_Achr6G05280_001 I 0.000
GSMUA_Achr7G09980_001 Musa acuminata GSMUA_Achr7G09980_001 I 0.000
GSMUA_Achr9G28570_001 Musa acuminata GSMUA_Achr9G28570_001 I 0.000
LPERR02G06800 Leersia perrieri LPERR02G06800 I 0.000
LPERR06G16860 Leersia perrieri LPERR06G16860 I 0.000
GLYMA18G14750 Glycine max GLYMA18G14750 I 0.000
GLYMA08G41450 Glycine max GLYMA08G41450 I 0.000
BGIOSGA006916 Oryza indica BGIOSGA006916 I 0.000
BGIOSGA023213 Oryza indica BGIOSGA023213 I 0.000
Bo2g010330 Brassica oleracea Bo2g010330 I 0.000
Bo9g171430 Brassica oleracea Bo9g171430 I 0.000
Bra008976 Brassica rapa Bra008976 I 0.000
Bra023317 Brassica rapa Bra023317 I 0.000
BRADI1G36750 Brachypodium distachyon BRADI1G36750 I 0.000
BRADI3G07540 Brachypodium distachyon BRADI3G07540 I 0.000
F775_05429 Aegilops tauschii F775_05429 I 0.000
MTR_3g436010 Medicago truncatula MTR_3g436010 I 0.000
OB02G17160 Oryza brachyantha OB02G17160 I 0.000
OBART02G07840 Oryza barthii OBART02G07840 I 0.000
PGSC0003DMG401020784 Solanum tuberosum PGSC0003DMG401020784 I 0.000
POPTR_0006s26800 Populus trichocarpa POPTR_0006s26800 I 0.000
POPTR_0018s01530 Populus trichocarpa POPTR_0018s01530 I 0.000
PRUPE_ppa012064mg Prunus persica PRUPE_ppa012064mg I 0.000
Sb04g007060 Sorghum bicolor Sb04g007060 I 0.000
Sb10g023420 Sorghum bicolor Sb10g023420 I 0.000
HY5 Arabidopsis lyrata scaffold_601144.1 I 0.000
SELMODRAFT_173274 Selaginella moellendorffii SELMODRAFT_173274 I 0.000
SELMODRAFT_440988 Selaginella moellendorffii SELMODRAFT_440988 I 0.000
OS02G0203000 Oryza sativa OS02G0203000 I 0.000
ORUFI03G26360 Oryza rufipogon ORUFI03G26360 I 0.000
OBART06G20230 Oryza barthii OBART06G20230 I 0.000
OGLUM02G07920 Oryza glumaepatula OGLUM02G07920 I 0.000
OGLUM06G21280 Oryza glumaepatula OGLUM06G21280 I 0.000
OLONG_023968 Oryza longistaminata OLONG_023968 I 0.000
OMERI06G20830 Oryza meridionalis OMERI06G20830 I 0.000
ONIVA02G09400 Oryza nivara ONIVA02G09400 I 0.000
OPUNC02G07060 Oryza punctata OPUNC02G07060 I 0.000
OPUNC06G18440 Oryza punctata OPUNC06G18440 I 0.000
ORGLA02G0074000 Oryza glaberrima ORGLA02G0074000 I 0.000
SELMODRAFT_451330 Selaginella moellendorffii SELMODRAFT_451330 I 0.000