prox1b (Danio rerio)
Prospero

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF05044 (HPD) IPR007738 ENSDARG00000088810 T316450_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within lymphangiogenesis. Predicted to be active in nucleus. Is expressed in axial vasculature; caudal vein plexus; central nervous system; head; and lateral plate mesoderm. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PROX1
M03445_2.00 		Homo sapiens
BAAGRCGTCTTV
BAAGACGYCTTV		 SELEX
Jolma et al.(2013)
PROX1_1 		0.708 0.708
PROX1
M05691_2.00 		Homo sapiens
BAMGRCGTCDTV
BAHGACGYCKTV		 SELEX
Yin et al.(2017)
PROX1_eDBD_HT-SELEX 		0.708 0.708
PROX1
M05692_2.00 		Homo sapiens
BAAGRYGTCTTV
BAAGACRYCTTV		 SELEX
Yin et al.(2017)
PROX1_eDBD_Methyl-HT-SELEX 		0.708 0.708
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000106319 Prospero 498 653
ENSDARP00000137116 Prospero 498 653

Links

Other Prospero family TFs
Other Danio rerio TFs

88 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMXG00000011110 Astyanax mexicanus ENSAMXG00000011110 N 0.890
ENSONIG00000013505 Oreochromis niloticus ENSONIG00000013505 N 0.883
ENSMEUG00000013465 Macropus eugenii ENSMEUG00000013465 I 0.879
ENSXMAG00000008639 Xiphophorus maculatus ENSXMAG00000008639 N 0.856
ENSPFOG00000006645 Poecilia formosa ENSPFOG00000006645 N 0.851
ENSGACG00000019750 Gasterosteus aculeatus ENSGACG00000019750 N 0.847
ENSTNIG00000013016 Tetraodon nigroviridis ENSTNIG00000013016 N 0.824
ENSORLG00000005386 Oryzias latipes ENSORLG00000005386 N 0.766
prox1a Tetraodon nigroviridis ENSTNIG00000016378 I 0.747
ACOC_0000703501 Angiostrongylus costaricensis ACOC_0000703501 I 0.737
ENSGMOG00000001679 Gadus morhua ENSGMOG00000001679 I 0.734
PROX1 Oryctolagus cuniculus ENSOCUG00000008274 I 0.728
ENSONIG00000012467 Oreochromis niloticus ENSONIG00000012467 I 0.721
ENSTRUG00000012738 Takifugu rubripes ENSTRUG00000012738 I 0.721
D918_02805 Trichuris suis D918_02805 I 0.720
CGOC_0000822101 Cylicostephanus goldi CGOC_0000822101 I 0.720
SVUK_0000405601 Strongylus vulgaris SVUK_0000405601 I 0.720
LCUP011134 Lucilia cuprina LCUP011134 I 0.720
ANCDUO_15205 Ancylostoma duodenale ANCDUO_15205 I 0.720
ANCCEY_02877 Ancylostoma ceylanicum ANCCEY_02877 I 0.720
ANCCAN_23624 Ancylostoma caninum ANCCAN_23624 I 0.720
DICVIV_00921 Dictyocaulus viviparus DICVIV_00921 I 0.720
NECAME_07738 Necator americanus NECAME_07738 I 0.720
ANCCAN_24706 Ancylostoma caninum ANCCAN_24706 I 0.720
nOo.2.0.1.g10265 Onchocerca ochengi nOo.2.0.1.g10265 I 0.720
ENSPMAG00000006606 Petromyzon marinus ENSPMAG00000006606 I 0.718
prox1.L Xenopus laevis XB-GENE-485331 I 0.714
HCOI02128500 Haemonchus contortus HCOI02128500 I 0.714
prox1 Xenopus tropicalis XB-GENE-485327 I 0.714
ENSGACG00000014345 Gasterosteus aculeatus ENSGACG00000014345 I 0.714
PROX1 Sus scrofa ENSSSCG00000015584 I 0.708
Prox1 Rattus norvegicus ENSRNOG00000003694 I 0.708
PROX1 Taeniopygia guttata ENSTGUG00000002974 I 0.708
ENSBTAP00000014573-D1 Bos grunniens ENSBTAP00000014573-D1 I 0.708
Pvit_00353 Pogona vitticeps Pvit_00353 I 0.708
PROX1 Pan troglodytes ENSPTRG00000001974 I 0.708
Tal_R002989 Tyto alba Tal_R002989 I 0.708
Ogr11789 Ophisaurus gracilis Ogr11789 I 0.708
Gfo_R010932 Geospiza fortis Gfo_R010932 I 0.708
Alligator_sinensis_CCG014115.1 Alligator sinensis Alligator_sinensis_CCG014115.1 I 0.708
Brh_R001903 Buceros rhinoceros Brh_R001903 I 0.708
ENSP00000355925 Macaca fascicularis ENSP00000355925 I 0.708
Afo_R004723 Aptenodytes forsteri Afo_R004723 I 0.708
ENSPPYG00000000224 Pongo abelii ENSPPYG00000000224 I 0.708
PROX1 Gallus gallus ENSGALG00000009791 I 0.708
PROX1 Homo sapiens ENSG00000117707 D 0.708
PROX1 Felis catus ENSFCAG00000029702 I 0.708
PROX1 Gorilla gorilla ENSGGOG00000015130 I 0.708
ENSPSIG00000008098 Pelodiscus sinensis ENSPSIG00000008098 I 0.708
PROX1 Myotis lucifugus ENSMLUG00000006993 I 0.708
PROX1 Meleagris gallopavo ENSMGAG00000009635 I 0.708
ENSFALG00000012357 Ficedula albicollis ENSFALG00000012357 I 0.708
PROX1 Equus caballus ENSECAG00000019220 I 0.708
PROX1 Bos taurus ENSBTAG00000010978 I 0.708
ENSAPLG00000010950 Anas platyrhynchos ENSAPLG00000010950 I 0.708
ENSAMEG00000015776 Ailuropoda melanoleuca ENSAMEG00000015776 I 0.708
PROX1 Canis familiaris ENSCAFG00000012445 I 0.708
PROX1 Callithrix jacchus ENSCJAG00000015514 I 0.708
PROX1 Dasypus novemcinctus ENSDNOG00000001297 I 0.708
PROX1 Cavia porcellus ENSCPOG00000011987 I 0.708
PROX1 Macaca mulatta ENSMMUG00000011914 I 0.708
PROX1 Loxodonta africana ENSLAFG00000006344 I 0.708
ENSORLG00000001996 Oryzias latipes ENSORLG00000001996 I 0.708
ENSPANG00000017714 Papio anubis ENSPANG00000017714 I 0.708
PROX1 Anolis carolinensis ENSACAG00000006174 I 0.708
PROX1 Otolemur garnettii ENSOGAG00000017025 I 0.708
ENSOARG00000009324 Ovis aries ENSOARG00000009324 I 0.708
ENSNLEG00000014435 Nomascus leucogenys ENSNLEG00000014435 I 0.708
ENSMPUG00000013456 Mustela putorius furo ENSMPUG00000013456 I 0.708
Prox1 Mus musculus ENSMUSG00000010175 I 0.708
PROX1 Choloepus hoffmanni ENSCHOG00000010660 I 0.707
PROX1 Tursiops truncatus ENSTTRG00000003405 I 0.706
Prox1 Dipodomys ordii ENSDORG00000007622 I 0.706
ENSCSAG00000015530 Chlorocebus sabaeus ENSCSAG00000015530 I 0.701
ENSPFOG00000015503 Poecilia formosa ENSPFOG00000015503 I 0.701
Aan_R011488 Calypte anna Aan_R011488 I 0.701
SINV18378 Solenopsis invicta SINV18378 I 0.700
YQE_10516 Dendroctonus ponderosae YQE_10516 I 0.700
PROX1 Pteropus vampyrus ENSPVAG00000009067 I 0.700
PROX1 Microcebus murinus ENSMICG00000011593 I 0.700
AARA009757 Anopheles arabiensis AARA009757 I 0.700
PROX1 Ochotona princeps ENSOPRG00000005115 I 0.700
Cflo_00868--XP_392355.3_APIME Camponotus floridanus Cflo_00868--XP_392355.3_APIME I 0.700
AEPI001687 Anopheles epiroticus AEPI001687 I 0.700
ACUA003826 Anopheles culicifacies ACUA003826 I 0.700
AMIN002618 Anopheles minimus AMIN002618 I 0.700
D917_07791 Trichinella nativa D917_07791 I 0.700