HHAL008503-PA (Halyomorpha halys)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF03165 (MH1) IPR003619 HHAL008503-PA T325397_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL008503-PA SMAD 28 124

Links

Other SMAD family TFs
Other Halyomorpha halys TFs

8 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
CLEC004107 Cimex lectularius CLEC004107 I 0.866
RPRC003748 Rhodnius prolixus RPRC003748 N 0.866
ACEP23524 Atta cephalotes ACEP23524 I 0.763
Brh_R001114 Buceros rhinoceros Brh_R001114 I 0.737
ENSGMOG00000001314 Gadus morhua ENSGMOG00000001314 I 0.737
ENSAPLG00000011496 Anas platyrhynchos ENSAPLG00000011496 I 0.711
SMAR008230 Strigamia maritima SMAR008230 I 0.711
Tal_R011237 Tyto alba Tal_R011237 I 0.711