CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
Home
Tools
View cart
Bulk downloads
Database stats
Contact us
Help
Update Log
FAQ
Links
How to cite
Stat5b
(
Rattus norvegicus
)
STAT
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF02864 (STAT_bind)
IPR013801
ENSRNOG00000019075
T337652_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables DNA binding activity; DNA-binding transcription factor activity; and chromatin binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; luteinization; and receptor signaling pathway via JAK-STAT. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in growth hormone insensitivity syndrome with immune dysregulation 1 and growth hormone insensitivity syndrome with immune dysregulation 2. Orthologous to human STAT5B (signal transducer and activator of transcription 5B). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Stat5b
M09421_2.00
Mus musculus
NNTTCYMRGAAN
NTTCYKRGAANN
Misc
Kulakovskiy et al.(2013)
STA5B_MOUSE.H11MO.0.A
0.917
0.917
STAT5B
M09417_2.00
Homo sapiens
NNTTCYMRGAAN
NTTCYKRGAANN
Misc
Kulakovskiy et al.(2013)
STA5B_HUMAN.H11MO.0.A
0.900
0.900
STAT5B
M11371_2.00
Homo sapiens
NDWTTCYNGGAAWHN
NDWTTCCNRGAAWHN
Transfac
Matys et al.(2006)
V$STAT5B_01
0.900
0.900
Stat5a
M09420_2.00
Mus musculus
TTCYMRGAAN
NTTCYKRGAA
Misc
Kulakovskiy et al.(2013)
STA5A_MOUSE.H11MO.0.A
0.967
0.967
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000026354
STAT
332
582
FIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFDSQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNSSSNHLEDYNSMSVSWSQFNRENLPGRNYTFWQWFDGVMEVLK
ENSRNOP00000070284
STAT
318
554
ATITDIISALVTSTFIIEKQPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFDSQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNSSSNHLEDYNSMSVSWSQFNRENLPGRNYTFWQWFDGVMEVLK
Links
Other
STAT
family TFs
Other
Rattus norvegicus
TFs
110 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy