Stat6 (Rattus norvegicus)
STAT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02864 (STAT_bind) IPR013801 ENSRNOG00000025023 T337655_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in several processes, including cellular response to hydrogen peroxide; cellular response to reactive nitrogen species; and positive regulation of transcription by RNA polymerase II. Located in membrane raft and nucleus. Used to study asthma and renal fibrosis. Biomarker of asthma and myocarditis. Human ortholog(s) of this gene implicated in lipoid nephrosis; prostate carcinoma; and urinary schistosomiasis. Orthologous to human STAT6 (signal transducer and activator of transcription 6). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Stat6
M08173_2.00 		Mus musculus
NNBTTCYWVRGAANN
NNTTCYBWRGAAVNN		 ChIP-seq
Mathelier et al.(2014)
MA0520.1 		0.963 0.963
Stat6
M09418_2.00 		Mus musculus
BDBTTCHBDRGAAV
BTTCYHVDGAAVHV		 Misc
Kulakovskiy et al.(2013)
STAT6_MOUSE.H11MO.0.A 		0.963 0.963
Stat6
M09644_2.00 		Mus musculus
TTCCNNAGAA
TTCTNNGGAA		 Misc
Heinz et al.(2010)
Macrophage-Stat6_GSE38377 		0.963 0.963
Stat6
M09643_2.00 		Mus musculus
NNTTCYNNRGAA
TTCYNNRGAANN		 Misc
Heinz et al.(2010)
CD4-Stat6_GSE22104 		0.963 0.963
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000034983 STAT 273 526
ENSRNOP00000072301 STAT 273 526

Links

Other STAT family TFs
Other Rattus norvegicus TFs

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41 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action