TBX21 (Homo sapiens)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 ENSG00000073861 T339885_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
TBX21
M03546_2.00
Homo sapiens
GGTGTGAHDTMACACY

RGTGTKAHDTCACACC
SELEX
Jolma et al.(2013)
TBX21_1
(Direct) (Direct)
TBX21
M03547_2.00
Homo sapiens
DAGGTGTGAW

WTCACACCTH
SELEX
Jolma et al.(2013)
TBX21_2
(Direct) (Direct)
TBX21
M03548_2.00
Homo sapiens
TMACACYTNNDAGGTGTGA

TCACACCTHNNARGTGTKA
SELEX
Jolma et al.(2013)
TBX21_3
(Direct) (Direct)
TBX21
M03549_2.00
Homo sapiens
GGTGTGAWATCACACC

GGTGTGATWTCACACC
SELEX
Jolma et al.(2013)
TBX21_4
(Direct) (Direct)
TBX21
M03550_2.00
Homo sapiens
DAGGTGTGAW

WTCACACCTH
SELEX
Jolma et al.(2013)
TBX21_5
(Direct) (Direct)
TBX21
M03551_2.00
Homo sapiens
TSACACCWNMRAGGTGTGA

TCACACCTYKNWGGTGTSA
SELEX
Jolma et al.(2013)
TBX21_6
(Direct) (Direct)
TBX21
M05793_2.00
Homo sapiens
DAGGTGTKAN

NTMACACCTH
SELEX
Yin et al.(2017)
TBX21_eDBD_HT-SELEX
(Direct) (Direct)
TBX21
M05794_2.00
Homo sapiens
DASGTGTKAW

WTMACACSTH
SELEX
Yin et al.(2017)
TBX21_eDBD_Methyl-HT-SELEX
(Direct) (Direct)
TBX21
M09425_2.00
Homo sapiens
NDSDRGSTGWBRN

NYVWCASCYHSHN
Misc
Kulakovskiy et al.(2013)
TBX21_HUMAN.H11MO.0.A
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Tbx21
M09428_2.00
Mus musculus
DNDDSTGWSDND

HNHSWCASHHNH
Misc
Kulakovskiy et al.(2013)
TBX21_MOUSE.H11MO.0.A
0.920 0.984
Tbx21
M09648_2.00
Mus musculus
ADGTGWSAHN

NDTSWCACHT
Misc
Heinz et al.(2010)
CD8-Tbet_GSE33802
0.920 0.984
Eomes
M00215_2.00
Mus musculus
RDGTGYBANN

NNTVRCACHY
PBM
Badis et al.(2009)
Eomes_0921
0.812 0.749
EOMES
M03563_2.00
Homo sapiens
DAGGTGTGAWNNN

NNNWTCACACCTH
SELEX
Jolma et al.(2013)
EOMES_1
0.812 0.743
EOMES
M03564_2.00
Homo sapiens
TVACACNTNNNDRNGTGTGA

TCACACNYHNNNANGTGTBA
SELEX
Jolma et al.(2013)
EOMES_2
0.812 0.743
EOMES
M02752_2.00
Homo sapiens
AGGTGTGAW

WTCACACCT
SELEX
Jolma et al.(2010)
EOMES_monomer
0.812 0.743
EOMES
M05807_2.00
Homo sapiens
DAGGTGTGAN

NTCACACCTH
SELEX
Yin et al.(2017)
EOMES_eDBD_HT-SELEX
0.812 0.743
EOMES
M09647_2.00
Homo sapiens
ARGTGWKAAN

NTTMWCACYT
Misc
Heinz et al.(2010)
H9-Eomes_GSE26097
0.812 0.743
EOMES
M05808_2.00
Homo sapiens
NABGTGYKAH

DTMRCACVTN
SELEX
Yin et al.(2017)
EOMES_eDBD_Methyl-HT-SELEX
0.812 0.743
Tbr1
M01028_2.00
Mus musculus
DTVRCAMNYH

DRNKTGYBAH
PBM
SebePedros et al.(2013)
pTH2659
0.766 0.732
TBR1
M03560_2.00
Homo sapiens
AGGTGTGAAN

NTTCACACCT
SELEX
Jolma et al.(2013)
TBR1_1
0.766 0.732
TBR1
M03561_2.00
Homo sapiens
RAGGTGTGAAH

DTTCACACCTY
SELEX
Jolma et al.(2013)
TBR1_2
0.766 0.732
For this family, TFs with SR scores > 0.734 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000177694 T-box 139 326

Links

Other T-box family TFs
Other Homo sapiens TFs

162 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
AT3G27970 Arabidopsis thaliana AT3G27970 N 0.000
Bra033033 Brassica rapa Bra033033 N 0.000
cassava27353.m1 Manihot esculenta cassava27353.m1 N 0.000
Ciclev10015764m.g Citrus clementina Ciclev10015764m.g N 0.000
Eucgr.I01798 Eucalyptus grandis Eucgr.I01798 N 0.000
evm.TU.supercontig_39.83 Carica papaya evm.TU.supercontig_39.83 N 0.000
GLYMA19G11090 Glycine max GLYMA19G11090 N 0.000
Lus10008787.g Linum usitatissimum Lus10008787.g N 0.000
Lus10022230.g Linum usitatissimum Lus10022230.g N 0.000
MDP0000196563 Malus domestica MDP0000196563 N 0.000
orange1.1g018558m.g Citrus sinensis orange1.1g018558m.g N 0.000