TEAD1 (Homo sapiens)
TEA

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01285 (TEA) IPR000818 ENSG00000187079 T346530_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TEAD1
M03577_2.00		 Homo sapiens
DHGGAATGYN
NRCATTCCDH		 SELEX
Jolma et al.(2013)
TEAD1_1		 (Direct) (Direct)
TEAD1
M03578_2.00		 Homo sapiens
HGGWATKYNHGGAATGY
RCATTCCDNRMATWCCD		 SELEX
Jolma et al.(2013)
TEAD1_2		 (Direct) (Direct)
TEAD1
M05825_2.00		 Homo sapiens
HGGWATGYN
NRCATWCCD		 SELEX
Yin et al.(2017)
TEAD1_FL_HT-SELEX		 (Direct) (Direct)
TEAD1
M05826_2.00		 Homo sapiens
HGGWATGYN
NRCATWCCD		 SELEX
Yin et al.(2017)
TEAD1_FL_Methyl-HT-SELEX		 (Direct) (Direct)
TEAD1
M09434_2.00		 Homo sapiens
DBBNWGGAATGY
RCATTCCWNVVH		 Misc
Kulakovskiy et al.(2013)
TEAD1_HUMAN.H11MO.0.A		 (Direct) (Direct)
TEAD1
M11404_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF_01		 (Direct) (Direct)
TEAD1
M11405_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF_07		 (Direct) (Direct)
TEAD1
M11406_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF1_Q6_03		 (Direct) (Direct)
TEAD1
M11407_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF1_Q6_04		 (Direct) (Direct)
TEAD1
M11408_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tead1
M09438_2.00 		Mus musculus
BSYWGGAATGY
RCATTCCWRSV		 Misc
Kulakovskiy et al.(2013)
TEAD1_MOUSE.H11MO.0.A 		0.758 0.758
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000334754 TEA 5 128
ENSP00000354588 TEA 1 75
ENSP00000432587 TEA 96 159
ENSP00000435233 TEA 14 140
ENSP00000435977 TEA 14 139

Links

Other TEA family TFs
Other Homo sapiens TFs

154 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
TEAD1 Equus caballus ENSECAG00000008332 I 1.000
TEAD1 Pan troglodytes ENSPTRG00000039896 N 1.000
TEAD1 Echinops telfairi ENSETEG00000009056 N 1.000
Tead1 Rattus norvegicus ENSRNOG00000015488 I 1.000
Tead3 Dipodomys ordii ENSDORG00000010798 I 1.000
TEAD1 Callithrix jacchus ENSCJAG00000010263 I 1.000
ENSTSYG00000001514 Tarsius syrichta ENSTSYG00000001514 N 1.000
TEAD1 Taeniopygia guttata ENSTGUG00000015995 N 1.000
ENSPPYG00000003475 Pongo abelii ENSPPYG00000003475 I 1.000
TEAD1 Macaca mulatta ENSMMUG00000010875 N 1.000
TEAD1 Microcebus murinus ENSMICG00000007178 I 1.000
TEAD4 Meleagris gallopavo ENSMGAG00000013910 I 1.000
Tead1 Mus musculus ENSMUSG00000055320 D 1.000
TEAD1 Gorilla gorilla ENSGGOG00000003412 N 1.000
ENSOANG00000021775 Ornithorhynchus anatinus ENSOANG00000021775 N 1.000
ENSNLEG00000017672 Nomascus leucogenys ENSNLEG00000017672 N 1.000
TEAD1 Tursiops truncatus ENSTTRG00000006621 N 1.000
ENSSHAG00000015930 Sarcophilus harrisii ENSSHAG00000015930 I 1.000
ENSAPLG00000016417 Anas platyrhynchos ENSAPLG00000016417 N 1.000
Aan_R006597 Calypte anna Aan_R006597 N 1.000
Afo_R014607 Aptenodytes forsteri Afo_R014607 N 1.000
ENSP00000355332 Macaca fascicularis ENSP00000355332 N 1.000
PPAI001408 Phlebotomus papatasi PPAI001408 I 1.000
e_gw.291.69.1 Branchiostoma floridae e_gw.291.69.1 I 1.000
TEAD1 Bos taurus ENSBTAG00000032657 N 1.000
Gfo_R013616 Geospiza fortis Gfo_R013616 N 1.000
TEAD1 Canis familiaris ENSCAFG00000007976 I 1.000
TEAD1 Gallus gallus ENSGALG00000005415 I 0.974
TEAD3 Macaca mulatta ENSMMUG00000015909 I 0.972
ENSCSAVG00000007634 Ciona savignyi ENSCSAVG00000007634 I 0.971
TEAD3 Microcebus murinus ENSMICG00000000029 I 0.970
TEAD4 Procavia capensis ENSPCAG00000013738 I 0.970
TEAD1 Meleagris gallopavo ENSMGAG00000005493 I 0.963
ENSPSIG00000006176 Pelodiscus sinensis ENSPSIG00000006176 I 0.961
TEAD4 Takifugu rubripes ENSTRUG00000016489 I 0.961
TEAD1 Sorex araneus ENSSARG00000001748 N 0.959
ENSFALG00000003635 Ficedula albicollis ENSFALG00000003635 I 0.948
tead1b Danio rerio ENSDARG00000059483 I 0.948
ACHR008952 Anopheles christyi ACHR008952 I 0.941
Pvit_10291 Pogona vitticeps Pvit_10291 N 0.941
TEAD3 Pan troglodytes ENSPTRG00000018086 I 0.941
AEPI008594 Anopheles epiroticus AEPI008594 I 0.941
TEAD4 Homo sapiens ENSG00000197905 D 0.939
Alligator_sinensis_CCG020461.1 Alligator sinensis Alligator_sinensis_CCG020461.1 I 0.937
TEAD1 Loxodonta africana ENSLAFG00000016484 I 0.935
tead1b Tetraodon nigroviridis ENSTNIG00000009360 N 0.935
tead1b Takifugu rubripes ENSTRUG00000017473 N 0.935
TEAD1 Oryctolagus cuniculus ENSOCUG00000007955 I 0.935
BGIBMGA001129 Bombyx mori BGIBMGA001129 I 0.932
TEAD4 Oryzias latipes ENSORLG00000002553 I 0.926
TEAD3 Tursiops truncatus ENSTTRG00000009434 I 0.925
tead1.S Xenopus laevis XB-GENE-5909161 N 0.924
ENSLOCG00000009736 Lepisosteus oculatus ENSLOCG00000009736 I 0.923
TEAD3 Canis familiaris ENSCAFG00000001326 I 0.923
Tead4 Mus musculus ENSMUSG00000030353 D 0.922
CPIJ013490 Culex quinquefasciatus CPIJ013490 I 0.919
CpipJ_CPIJ013490 Culex pipiens CpipJ_CPIJ013490 I 0.919
TEAD3 Otolemur garnettii ENSOGAG00000002943 I 0.914
ENSONIG00000005991 Oreochromis niloticus ENSONIG00000005991 N 0.903
TEAD3 Loxodonta africana ENSLAFG00000014818 I 0.902
TEAD3 Equus caballus ENSECAG00000015056 I 0.902
D918_02241 Trichuris suis D918_02241 I 0.892
HelroG146479 Helobdella robusta HelroG146479 I 0.890
Pvit_05988 Pogona vitticeps Pvit_05988 I 0.890
tead1a Danio rerio ENSDARG00000028159 I 0.884
ENSLACG00000013349 Latimeria chalumnae ENSLACG00000013349 I 0.878
SMAR013465 Strigamia maritima SMAR013465 I 0.878
SMAR011013 Strigamia maritima SMAR011013 I 0.878
Alligator_sinensis_CCG011289.1 Alligator sinensis Alligator_sinensis_CCG011289.1 I 0.877
ENSAMXG00000013086 Astyanax mexicanus ENSAMXG00000013086 I 0.877
tead3a Takifugu rubripes ENSTRUG00000011546 I 0.872
TEAD1 Sus scrofa ENSSSCG00000013399 I 0.867
tead1b Gasterosteus aculeatus ENSGACG00000015715 I 0.867
Ogr18322 Ophisaurus gracilis Ogr18322 I 0.862
TEAD1 Pteropus vampyrus ENSPVAG00000001503 I 0.855
Tead1 Dipodomys ordii ENSDORG00000013529 N 0.855
TEAD1 Choloepus hoffmanni ENSCHOG00000001087 N 0.855
TEAD1 Vicugna pacos ENSVPAG00000005288 N 0.855
tead3b Takifugu rubripes ENSTRUG00000018177 I 0.846
Myotis_brandtii_TEAD3_10017764 Myotis brandtii Myotis_brandtii_TEAD3_10017764 I 0.840
TEAD2 Erinaceus europaeus ENSEEUG00000012244 I 0.840
TEAD1 Cavia porcellus ENSCPOG00000001830 N 0.840
ENSGMOG00000015271 Gadus morhua ENSGMOG00000015271 I 0.838
ENSLACG00000016717 Latimeria chalumnae ENSLACG00000016717 N 0.833
TEAD3 Pteropus vampyrus ENSPVAG00000002764 I 0.833
ENSGMOG00000010731 Gadus morhua ENSGMOG00000010731 I 0.833
ENSSTOG00000010621 Ictidomys tridecemlineatus ENSSTOG00000010621 I 0.831
AGAP000512 Anopheles gambiae AGAP000512 I 0.830
TEAD2 Ornithorhynchus anatinus ENSOANG00000013933 N 0.827
ENSDORG00000004435 Dipodomys ordii ENSDORG00000004435 I 0.826
AAEL014670 Aedes aegypti AAEL014670 I 0.826
TsM_000210300 Taenia solium TsM_000210300 I 0.824
TEAD1 Procavia capensis ENSPCAG00000013657 I 0.823
ENSLOCG00000004054 Lepisosteus oculatus ENSLOCG00000004054 I 0.823
ENSLACG00000016444 Latimeria chalumnae ENSLACG00000016444 I 0.821
ENSPFOG00000003170 Poecilia formosa ENSPFOG00000003170 I 0.819
TEAD2 Sus scrofa ENSSSCG00000025568 I 0.816
ECANG7_01760 Echinococcus canadensis ECANG7_01760 I 0.813
tead1b Oryzias latipes ENSORLG00000007439 I 0.806
tead3a Gasterosteus aculeatus ENSGACG00000009758 I 0.800
egl-44 Caenorhabditis elegans WBGene00001208 I 0.798
TEAD3 Taeniopygia guttata ENSTGUG00000001691 I 0.793
sd Drosophila melanogaster FBgn0003345 D 0.787
GA21152 Drosophila pseudoobscura FBgn0081140 I 0.787
L798_06691 Zootermopsis nevadensis L798_06691 N 0.787
ENSCING00000019408 Ciona intestinalis ENSCING00000019408 I 0.786
LCUP007338 Lucilia cuprina LCUP007338 I 0.783
ENSPFOG00000013997 Poecilia formosa ENSPFOG00000013997 I 0.783
AMEM005509 Anopheles merus AMEM005509 I 0.776
ENSGALG00000000953 Gallus gallus ENSGALG00000000953 I 0.773
CBG02541 Caenorhabditis briggsae CBG02541 I 0.769
nRc.2.0.1.g07693 Romanomermis culicivorax nRc.2.0.1.g07693 I 0.767
TEAD3 Gorilla gorilla ENSGGOG00000001847 I 0.765
NEMVEDRAFT_v1g86806 Nematostella vectensis NEMVEDRAFT_v1g86806 I 0.764
EFV53558 Trichinella spiralis EFV53558 I 0.760
tead3b Danio rerio ENSDARG00000063649 I 0.760
ENSMPUG00000013114 Mustela putorius furo ENSMPUG00000013114 I 0.758
ENSOARG00000008069 Ovis aries ENSOARG00000008069 I 0.758
ENSOARG00000012126 Ovis aries ENSOARG00000012126 I 0.758
ENSCSAG00000004676 Chlorocebus sabaeus ENSCSAG00000004676 I 0.758
ENSMPUG00000003624 Mustela putorius furo ENSMPUG00000003624 I 0.755
tead1a Tetraodon nigroviridis ENSTNIG00000008857 I 0.754
Cmyd_10009267 Chelonia mydas Cmyd_10009267 I 0.750
ENSCJAG00000018829 Callithrix jacchus ENSCJAG00000018829 I 0.748
TEAD4 Dasypus novemcinctus ENSDNOG00000030589 I 0.745
CLEC025393 Cimex lectularius CLEC025393 I 0.744
TEAD3 Homo sapiens ENSG00000007866 D 0.743
MDOA005382 Musca domestica MDOA005382 I 0.735
AMEC005819 Anopheles melas AMEC005819 I 0.735
TEAD3 Bos taurus ENSBTAG00000019495 I 0.733
tead1a Takifugu rubripes ENSTRUG00000005940 I 0.731
TEAD3 Felis catus ENSFCAG00000012905 I 0.728
TEAD1 Anolis carolinensis ENSACAG00000004642 I 0.726
ENSPFOG00000012196 Poecilia formosa ENSPFOG00000012196 N 0.726
ENSSHAG00000012780 Sarcophilus harrisii ENSSHAG00000012780 I 0.726
Aqu1.216869 Amphimedon queenslandica Aqu1.216869 I 0.725
HHAL001589-PA Halyomorpha halys HHAL001589-PA I 0.717
GL22923 Drosophila persimilis FBgn0160513 I 0.717
TEAD2 Anolis carolinensis ENSACAG00000017423 I 0.713
ENSAMEG00000000632 Ailuropoda melanoleuca ENSAMEG00000000632 I 0.712
D917_06432 Trichinella nativa D917_06432 I 0.712
TEAD1 Erinaceus europaeus ENSEEUG00000012549 N 0.710
ENSBTAP00000021752-D1 Bos grunniens ENSBTAP00000021752-D1 N 0.710
ENSXMAG00000003088 Xiphophorus maculatus ENSXMAG00000003088 N 0.710
TEAD4 Gallus gallus ENSGALG00000014342 N 0.710
GM22588 Drosophila sechellia FBgn0177458 I 0.710
ENSGMOG00000002217 Gadus morhua ENSGMOG00000002217 N 0.710
ENSMEUG00000003932 Macropus eugenii ENSMEUG00000003932 N 0.710
Alligator_sinensis_CCG004256.1 Alligator sinensis Alligator_sinensis_CCG004256.1 N 0.710
ENSAMXG00000010081 Astyanax mexicanus ENSAMXG00000010081 I 0.710
NBR_0001654801 Nippostrongylus brasiliensis NBR_0001654801 I 0.704
ENSSTOG00000024296 Ictidomys tridecemlineatus ENSSTOG00000024296 I 0.704
NBR_0002152001 Nippostrongylus brasiliensis NBR_0002152001 I 0.704