TF Information

TEC1 *(Saccharomyces cerevisiae)* TEA
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF01285 (TEA)	IPR000818	YBR083W	T346956_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including invasive growth in response to glucose limitation; positive regulation of transposition, RNA-mediated; and pseudohyphal growth. Located in nucleus. Part of Tec1p-Ste12p-Dig1p complex. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Orthologous to several human genes including TEAD1 (TEA domain transcription factor 1); TEAD2 (TEA domain transcription factor 2); and TEAD3 (TEA domain transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
TEC1 M00072_2.00	Saccharomyces cerevisiae	VRGAATGY	RCATTCYB	PBM Badis et al.(2008) TEC1_2092	(Direct)	(Direct)
TEC1 M01568_2.00	Saccharomyces cerevisiae	NNVRGAATGY	RCATTCYBNN	PBM Zhu et al.(2009) Tec1	(Direct)	(Direct)
TEC1 M07499_2.00	Saccharomyces cerevisiae	VRGAATGY	RCATTCYB	PBM, CSA and or DIP-chip Mathelier et al.(2014) MA0406.1	(Direct)	(Direct)
TEC1 M08610_2.00	Saccharomyces cerevisiae	NNNNNNRRGAATGTDNNNNN	NNNNNHACATTCYYNNNNNN	Misc DeBoer et al.(2011) YBR083W_815	(Direct)	(Direct)
TEC1 M11411_2.00	Saccharomyces cerevisiae	Transfac license required	Transfac license required	Transfac Matys et al.(2006) F$TEC1_02	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
For this family, TFs with SR scores > 0.700* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M00072_2.00	TEA	51	338	HPQFELVNTGLGAKSDDLKSPSAKATFTDKQRKNEVPNISVSNYFPGQSSETSSTTESWTIGCDKWSEKVEEAFLEALRLIMKNGTTKIKIRNANFGRNELISLYIKHKTNEFRTKKQISSHIQVWKKTIQNKIKDSLTLSSKEKELLHLIEHGAEQTTENSNLFYDIFEEIIDSLPSVSDSGSLTPKNLYVSNNSSGLSVHSKLLTPITASNEKKIENFIKTNAASQAKTPLIYAKHIYENIDGYKCVPSKRPLEQLSPTELHQGDRPNKASFSNKKAILESAKKIE
M00072_2.00	TEA	332	470	ESAKKIEKEQRKIINKYQRISRIQEHESNPEFSSNSNSGSEYESEEEVVPRSATVTQLQSRPVPYYKNNGMPYSLSKVRGRPMYPRPAEDAYNANYIQGLPQYQTSYFSQLLLSSPQHYEHSPHQRNFTPSNQSHGNFY
M01568_2.00	TEA	67	356	HPQFELVNTGLGAKSDDLKSPSAKATFTDKQRKNEVPNISVSNYFPGQSSETSSTTESWTIGCDKWSEKVEEAFLEALRLIMKNGTTKIKIRNANFGRNELISLYIKHKTNEFRTKKQISSHIQVWKKTIQNKIKDSLTLSSKEKELLHLIEHGAEQTTENSNLFYDIFEEIIDSLPSVSDSGSLTPKNLYVSNNSSGLSVHSKLLTPITASNEKKIENFIKTNAASQAKTPLIYAKHIYENIDGYKCVPSKRPLEQLSPTELHQGDRPNKASFSNKKAILESAKKIEIE
M01568_2.00	TEA	349	486	SAKKIEIEQRKIINKYQRISRIQEHESNPEFSSNSNSGSEYESEEEVVPRSATVTQLQSRPVPYYKNNGMPYSLSKVRGRPMYPRPAEDAYNANYIQGLPQYQTSYFSQLLLSSPQHYEHSPHQRNFTPSNQSHGNFY

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
YBR083W	TEA	67	356	HPQFELVNTGLGAKSDDLKSPSAKATFTDKQRKNEVPNISVSNYFPGQSSETSSTTESWTIGCDKWSEKVEEAFLEALRLIMKNGTTKIKIRNANFGRNELISLYIKHKTNEFRTKKQISSHIQVWKKTIQNKIKDSLTLSSKEKELLHLIEHGAEQTTENSNLFYDIFEEIIDSLPSVSDSGSLTPKNLYVSNNSSGLSVHSKLLTPITASNEKKIENFIKTNAASQAKTPLIYAKHIYENIDGYKCVPSKRPLEQLSPTELHQGDRPNKASFSNKKAILESAKKIEIE
YBR083W	TEA	349	486	SAKKIEIEQRKIINKYQRISRIQEHESNPEFSSNSNSGSEYESEEEVVPRSATVTQLQSRPVPYYKNNGMPYSLSKVRGRPMYPRPAEDAYNANYIQGLPQYQTSYFSQLLLSSPQHYEHSPHQRNFTPSNQSHGNFY

Links
Other TEA family TFs
Other *Saccharomyces cerevisiae* TFs

Invalid Input OrderBy

4 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action