MITF (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000187098 T034335_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MITF
M08058_2.00		 Homo sapiens
NNNDRTCACGTGAYHNNN
NNNDRTCACGTGAYHNNN		 ChIP-seq
Mathelier et al.(2014)
MA0620.2		 (Direct) (Direct)
MITF
M08740_2.00		 Homo sapiens
YCAYGTGACH
DGTCACRTGR		 Misc
Kulakovskiy et al.(2013)
MITF_HUMAN.H11MO.0.A		 (Direct) (Direct)
MITF
M09880_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MITF_Q4		 (Direct) (Direct)
MITF
M09881_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MITF_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Mitf
M01741_2.00 		Mus musculus
NCDCGTGAYN
NRTCACGHGN		 PBM
Weirauch et al.(2014)
pTH5465 		0.914 1.000
Mitf
M08765_2.00 		Mus musculus
BCHYGTGACY
RGTCACRDGV		 Misc
Kulakovskiy et al.(2013)
MITF_MOUSE.H11MO.0.A 		0.914 1.000
Mitf
M09475_2.00 		Mus musculus
GTCACRWGVB
VBCWYGTGAC		 Misc
Heinz et al.(2010)
MastCells-MITF_GSE48085 		0.914 1.000
Tfe3
M01715_2.00 		Mus musculus
NCDCRTGAYN
NRTCAYGHGN		 PBM
Weirauch et al.(2014)
pTH5057 		0.914 0.981
Tfe3
M05833_2.00 		Mus musculus
CACGTGAY
RTCACGTG		 SMiLE-seq
Isakova et al.(2017)
TFE3 		0.914 0.981
Tfe3
M08743_2.00 		Mus musculus
TCACGTGACH
DGTCACGTGA		 Misc
Kulakovskiy et al.(2013)
TFE3_MOUSE.H11MO.0.A 		0.914 0.981
Tfe3
M09884_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFEA_01 		0.914 0.981
TFE3
M02773_2.00 		Homo sapiens
VNCACGTGMY
RKCACGTGNB		 SELEX
Jolma et al.(2013)
TFE3_1 		0.871 0.963
TFE3
M04058_2.00 		Homo sapiens
YVCACGTGAYN
NRTCACGTGBR		 SELEX
Yin et al.(2017)
TFE3_eDBD_HT-SELEX 		0.871 0.963
TFE3
M08709_2.00 		Homo sapiens
TCACGTGACH
DGTCACGTGA		 Misc
Kulakovskiy et al.(2013)
TFE3_HUMAN.H11MO.0.B 		0.871 0.963
TFE3
M09790_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFEA_Q6 		0.871 0.963
TFE3
M04059_2.00 		Homo sapiens
NRTCACATGBB
VVCATGTGAYN		 SELEX
Yin et al.(2017)
TFE3_eDBD_Methyl-HT-SELEX 		0.871 0.963
Tfec
M00755_2.00 		Mus musculus
NNCACGTGNN
NNCACGTGNN		 PBM
Weirauch et al.(2013)
pTH2885 		0.870 0.926
Tfec
M01736_2.00 		Mus musculus
NCNCRTGVYN
NRBCAYGNGN		 PBM
Weirauch et al.(2014)
pTH5065 		0.870 0.926
TFEC
M02778_2.00 		Homo sapiens
RNCACRTGAB
VTCAYGTGNY		 SELEX
Jolma et al.(2013)
TFEC_1 		0.870 0.907
TFEC
M04078_2.00 		Homo sapiens
NVCACGTGACN
NGTCACGTGBN		 SELEX
Yin et al.(2017)
TFEC_eDBD_HT-SELEX 		0.870 0.907
TFEC
M04079_2.00 		Homo sapiens
VNCATGTGAYN
NRTCACATGNB		 SELEX
Yin et al.(2017)
TFEC_eDBD_Methyl-HT-SELEX 		0.870 0.907
Tfeb
M01728_2.00 		Mus musculus
CWCGTGAY
RTCACGWG		 PBM
Weirauch et al.(2014)
pTH5072 		0.855 0.889
TFEB
M02781_2.00 		Homo sapiens
RNCACGTGAY
RTCACGTGNY		 SELEX
Jolma et al.(2013)
TFEB_1 		0.855 0.889
TFEB
M02727_2.00 		Homo sapiens
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2010)
TFEB_dimer 		0.855 0.889
TFEB
M04088_2.00 		Homo sapiens
YVCACGTGAYN
NRTCACGTGBR		 SELEX
Yin et al.(2017)
TFEB_eDBD_HT-SELEX 		0.855 0.889
TFEB
M08718_2.00 		Homo sapiens
CACGTGAYY
RRTCACGTG		 Misc
Kulakovskiy et al.(2013)
TFEB_HUMAN.H11MO.0.C 		0.855 0.889
Tfeb
M08753_2.00 		Mus musculus
CACGTGAYY
RRTCACGTG		 Misc
Kulakovskiy et al.(2013)
TFEB_MOUSE.H11MO.0.C 		0.855 0.889
TFEB
M04089_2.00 		Homo sapiens
VNCATGTGAYN
NRTCACATGNB		 SELEX
Yin et al.(2017)
TFEB_eDBD_Methyl-HT-SELEX 		0.855 0.889
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000295600 bHLH 306 359
ENSP00000324246 bHLH 199 252
ENSP00000324443 bHLH 290 343
ENSP00000327867 bHLH 305 358
ENSP00000377880 bHLH 205 258
ENSP00000391803 bHLH 312 365
ENSP00000398639 bHLH 296 349
ENSP00000418845 bHLH 254 307
ENSP00000435909 bHLH 143 196

Links

Other bHLH family TFs
Other Homo sapiens TFs

243 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AB03766.1 Alternaria brassicicola AB03766.1 N
BAUCODRAFT_70890 Baudoinia compniacensis BAUCODRAFT_70890 I
COCC4DRAFT_76975 Bipolaris maydis COCC4DRAFT_76975 N
COCCADRAFT_107226 Bipolaris zeicola COCCADRAFT_107226 N
COCMIDRAFT_106375 Bipolaris oryzae COCMIDRAFT_106375 N
COCSADRAFT_272980 Bipolaris sorokiniana COCSADRAFT_272980 N
COCSADRAFT_34658 Bipolaris sorokiniana COCSADRAFT_34658 N
COCVIDRAFT_14231 Bipolaris victoriae COCVIDRAFT_14231 N
DOTSEDRAFT_54819 Dothistroma septosporum DOTSEDRAFT_54819 I
estExt_fgenesh1_pg.C_chr_60424 Mycosphaerella graminicola estExt_fgenesh1_pg.C_chr_60424 I
estExt_Genewise1Plus.C_13865 Mycosphaerella fijiensis estExt_Genewise1Plus.C_13865 I
LEMA_P047940.1 Leptosphaeria maculans LEMA_P047940.1 N
MPH_00746 Macrophomina phaseolina MPH_00746 N
MYCFIDRAFT_204155 Pseudocercospora fijiensis MYCFIDRAFT_204155 I
Mycgr3G109947 Zymoseptoria tritici Mycgr3G109947 I
SBOR_8201 Sclerotinia borealis SBOR_8201 N
SEPMUDRAFT_149208 Sphaerulina musiva SEPMUDRAFT_149208 N
SETTUDRAFT_134164 Setosphaeria turcica SETTUDRAFT_134164 N
SNOG_04842 Phaeosphaeria nodorum SNOG_04842 N
SNOG_04842 Stagonospora nodorum SNOG_04842 N