GFI1B (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000165702 T095034_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GFI1B
M00239_2.00		 Homo sapiens
NNAAATCWSDN
NHSWGATTTNN		 PBM
Barrera et al.(2016)
GFI1B_A204T		 (Direct) (Direct)
GFI1B
M00240_2.00		 Homo sapiens
NNAAATCWSDN
NHSWGATTTNN		 PBM
Barrera et al.(2016)
GFI1B_REF		 (Direct) (Direct)
GFI1B
M04523_2.00		 Homo sapiens
NMAATCASDGCNNBBCACTNN
NNAGTGVVNNGCHSTGATTKN		 SELEX
Yin et al.(2017)
GFI1B_eDBD_HT-SELEX		 (Direct) (Direct)
GFI1B
M04524_2.00		 Homo sapiens
NMAATCASWGCDNNBCACTHN
NDAGTGVNNHGCWSTGATTKN		 SELEX
Yin et al.(2017)
GFI1B_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
GFI1B
M08909_2.00		 Homo sapiens
MAATCWSDGY
RCHSWGATTK		 Misc
Kulakovskiy et al.(2013)
GFI1B_HUMAN.H11MO.0.A		 (Direct) (Direct)
GFI1B
M10243_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GFI1B_01		 (Direct) (Direct)
GFI1B
M10244_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GFI1B_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
sens
M03666_2.00 		Drosophila melanogaster
TGCWSTGATTTATY
RATAAATCASWGCA		 SELEX
Nitta et al.(2015)
sens_1 		0.789 0.859
sens
M06056_2.00 		Drosophila melanogaster
AAATCACDGC
GCHGTGATTT		 B1H
Zhu et al.(2011)
sens_SANGER_10_FBgn0002573 		0.789 0.859
sens
M06057_2.00 		Drosophila melanogaster
NNNNAAATCACRGCH
DGCYGTGATTTNNNN		 B1H
Zhu et al.(2011)
sens_SOLEXA_5_FBgn0002573 		0.789 0.859
Gfi1b
M08098_2.00 		Mus musculus
MAATCWCWGCH
DGCWGWGATTK		 ChIP-seq
Mathelier et al.(2014)
MA0483.1 		0.825 0.993
Gfi1b
M08977_2.00 		Mus musculus
MAAYCACWGH
DCWGWGRTTK		 Misc
Kulakovskiy et al.(2013)
GFI1B_MOUSE.H11MO.0.A 		0.825 0.993
Gfi1b
M09514_2.00 		Mus musculus
MAATCWSWGC
GCWSWGATTK		 Misc
Heinz et al.(2010)
HPC7-Gfi1b_GSE22178 		0.825 0.993
sens-2
M06165_2.00 		Drosophila melanogaster
RYAAATCWSDGCAYNC
GNRTGCHSWGATTTRY		 B1H
Zhu et al.(2011)
sens-2_SANGER_2.5_FBgn0051632 		0.782 0.833
GFI1
M00238_2.00 		Homo sapiens
NWAWMNNNN
NNNNKWTWN		 PBM
Barrera et al.(2016)
GFI1_REF 		0.781 0.877
GFI1
M04507_2.00 		Homo sapiens
BMAATCACDGCNHBBCACTMN
NKAGTGVVDNGCHGTGATTKV		 SELEX
Yin et al.(2017)
GFI1_eDBD_HT-SELEX 		0.781 0.877
Gfi1
M02668_2.00 		Rattus norvegicus
NMAATCWVHS
SDBWGATTKN		 SELEX
Mathelier et al.(2014)
MA0038.1 		0.781 0.877
GFI1
M08905_2.00 		Homo sapiens
MAATCWSWGY
RCWSWGATTK		 Misc
Kulakovskiy et al.(2013)
GFI1_HUMAN.H11MO.0.C 		0.781 0.877
Gfi1
M08984_2.00 		Mus musculus
MAATCWSWGY
RCWSWGATTK		 Misc
Kulakovskiy et al.(2013)
GFI1_MOUSE.H11MO.0.C 		0.781 0.877
GFI1
M10235_2.00 		Homo sapiens
NNNNNNNRCHSWGATTTDNNBNNN
NNNVNNHAAATCWSDGYNNNNNNN		 Transfac
Matys et al.(2006)
V$GFI1_01 		0.781 0.877
GFI1
M10236_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GFI1_Q6_01 		0.781 0.877
GFI1
M04508_2.00 		Homo sapiens
NNAGTGVVNHGCWSTGATTKV
BMAATCASWGCDNBBCACTNN		 SELEX
Yin et al.(2017)
GFI1_eDBD_Methyl-HT-SELEX 		0.781 0.877
GFI1
M00236_2.00 		Homo sapiens
NAATMNNNN
NNNNKATTN		 PBM
Barrera et al.(2016)
GFI1_L400F 		0.779 0.870
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00239_2.00 C2H2 ZF 6 29
M00239_2.00 C2H2 ZF 35 57
M00239_2.00 C2H2 ZF 63 85
M00239_2.00 C2H2 ZF 91 113
M00239_2.00 C2H2 ZF 119 141
M00239_2.00 C2H2 ZF 147 170
M00240_2.00 C2H2 ZF 6 29
M00240_2.00 C2H2 ZF 35 57
M00240_2.00 C2H2 ZF 63 85
M00240_2.00 C2H2 ZF 91 113
M00240_2.00 C2H2 ZF 119 141
M00240_2.00 C2H2 ZF 147 170

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000344782 C2H2 ZF 163 186
ENSP00000344782 C2H2 ZF 192 214
ENSP00000344782 C2H2 ZF 220 242
ENSP00000344782 C2H2 ZF 248 270
ENSP00000344782 C2H2 ZF 276 298
ENSP00000344782 C2H2 ZF 304 327
ENSP00000361195 C2H2 ZF 163 186
ENSP00000361195 C2H2 ZF 192 214
ENSP00000361195 C2H2 ZF 220 242
ENSP00000361195 C2H2 ZF 248 270
ENSP00000361195 C2H2 ZF 276 298
ENSP00000361195 C2H2 ZF 304 327
ENSP00000361196 C2H2 ZF 174 196
ENSP00000361196 C2H2 ZF 202 224
ENSP00000361196 C2H2 ZF 230 252
ENSP00000361196 C2H2 ZF 258 281

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

196 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
30169.m006306 Ricinus communis 30169.m006306 N
cassava20476.m1 Manihot esculenta cassava20476.m1 N
Ciclev10004715m.g Citrus clementina Ciclev10004715m.g N
Eucgr.F04460 Eucalyptus grandis Eucgr.F04460 N
evm.TU.supercontig_34.30 Carica papaya evm.TU.supercontig_34.30 N
gene18499-v1.0-hybrid Fragaria vesca gene18499-v1.0-hybrid N
Gorai.002G110100 Gossypium raimondii Gorai.002G110100 N
Lus10031172.g Linum usitatissimum Lus10031172.g N
orange1.1g009215m.g Citrus sinensis orange1.1g009215m.g N
PK21020.1 Cannabis sativa PK21020.1 N
Pm011106 Prunus mume Pm011106 N
POPTR_0005s09790 Populus trichocarpa POPTR_0005s09790 N
PRUPE_ppa004256mg Prunus persica PRUPE_ppa004256mg N
SapurV1A.0404s0280 Salix purpurea SapurV1A.0404s0280 N
TCM_033446 Theobroma cacao TCM_033446 N