HMBOX1 (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000147421 T209858_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HMBOX1
M03167_2.00		 Homo sapiens
BKTAACTARB
VYTAGTTAMV		 SELEX
Jolma et al.(2013)
HMBOX1_1		 (Direct) (Direct)
HMBOX1
M05180_2.00		 Homo sapiens
BTAACYAGB
VCTRGTTAV		 SELEX
Yin et al.(2017)
HMBOX1_eDBD_HT-SELEX		 (Direct) (Direct)
HMBOX1
M05181_2.00		 Homo sapiens
NTAACTAGB
VCTAGTTAN		 SELEX
Yin et al.(2017)
HMBOX1_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hmbox1
M00419_2.00 		Mus musculus
NNNGWNNN
NNNWCNNN		 PBM
Berger et al.(2008)
Hmbox1_2674 		0.867 1.000
Hnf1b
M00408_2.00 		Mus musculus
NNHWCNNN
NNNGWDNN		 PBM
Berger et al.(2008)
Tcf2_0913 		0.638 0.368
Hnf1a
M00171_2.00 		Mus musculus
HTAAYYNN
NNRRTTAD		 PBM
Badis et al.(2009)
Tcf1_2666 		0.638 0.368
Hnf1a
M00444_2.00 		Mus musculus
HTAAYYNNN
NNNRRTTAD		 PBM
Berger et al.(2008)
Tcf1_2666 		0.638 0.368
HNF1A
M03150_2.00 		Homo sapiens
NGTTAATNATTAAYN
NRTTAATNATTAACN		 SELEX
Jolma et al.(2013)
HNF1A_1 		0.638 0.368
HNF1B
M03245_2.00 		Homo sapiens
GTTAATNATTAAY
RTTAATNATTAAC		 SELEX
Jolma et al.(2013)
HNF1B_1 		0.638 0.368
HNF1B
M03246_2.00 		Homo sapiens
NGTTAATNATTAAYN
NRTTAATNATTAACN		 SELEX
Jolma et al.(2013)
HNF1B_2 		0.638 0.368
HNF1A
M09144_2.00 		Homo sapiens
DGTTAATKATTAACH
DGTTAATMATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1A_HUMAN.H11MO.0.C 		0.638 0.368
HNF1B
M09168_2.00 		Homo sapiens
DGTTAATRATTAACH
DGTTAATYATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1B_HUMAN.H11MO.0.A 		0.638 0.368
Hnf1a
M09191_2.00 		Mus musculus
RGTTAATNWTTDMHN
NDKHAAWNATTAACY		 Misc
Kulakovskiy et al.(2013)
HNF1A_MOUSE.H11MO.0.A 		0.638 0.368
Hnf1b
M09179_2.00 		Mus musculus
DGTTAATRATTAACH
DGTTAATYATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1B_MOUSE.H11MO.0.A 		0.638 0.368
HNF1A
M10690_2.00 		Homo sapiens
RGTTAATDWTTRMHV
BDKYAAWHATTAACY		 Transfac
Matys et al.(2006)
V$HNF1_01 		0.638 0.368
HNF1A
M10691_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1A_Q4 		0.638 0.368
HNF1A
M10692_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1A_Q5 		0.638 0.368
HNF1B
M10758_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1B_Q6_01 		0.638 0.368
HNF1B
M10759_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1B_Q6 		0.638 0.368
HNF1A
M10693_2.00 		Homo sapiens
DGBTAATBAWTHAMYWM
KWRKTDAWTVATTAVCH		 Transfac
Matys et al.(2006)
V$HNF1_C 		0.638 0.368
HNF1B
M10760_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LFA1_Q6 		0.638 0.368
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000287701 Homeodomain 268 339
ENSP00000380516 Homeodomain 268 339
ENSP00000430059 Homeodomain 268 339
ENSP00000430110 Homeodomain 268 339
ENSP00000452827 Homeodomain 268 339
ENSP00000453185 Homeodomain 268 310
ENSP00000453211 Homeodomain 268 339
ENSP00000475196 Homeodomain 268 339

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

237 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
BGIOSGA026544 Oryza indica BGIOSGA026544 N 0.000
BGIOSGA026545 Oryza indica BGIOSGA026545 N 0.000
DREB1H Oryza indica BGIOSGA029416 I 0.000
DREB1B Oryza indica BGIOSGA029417 N 0.000
BRADI1G49570 Brachypodium distachyon BRADI1G49570 I 0.000
BRADI4G35630 Brachypodium distachyon BRADI4G35630 I 0.000
BRADI4G35650 Brachypodium distachyon BRADI4G35650 I 0.000
F775_00827 Aegilops tauschii F775_00827 I 0.000
F775_27111 Aegilops tauschii F775_27111 I 0.000
GRMZM2G069126 Zea mays GRMZM2G069126 I 0.000
GRMZM2G069146 Zea mays GRMZM2G069146 I 0.000
GRMZM2G124011 Zea mays GRMZM2G124011 I 0.000
GRMZM2G175856 Zea mays GRMZM2G175856 N 0.000
LPERR09G12950 Leersia perrieri LPERR09G12950 I 0.000
OGLUM08G23770 Oryza glumaepatula OGLUM08G23770 N 0.000
OGLUM09G17420 Oryza glumaepatula OGLUM09G17420 I 0.000
OMERI09G12480 Oryza meridionalis OMERI09G12480 I 0.000
ONIVA09G17880 Oryza nivara ONIVA09G17880 N 0.000
ONIVA09G17890 Oryza nivara ONIVA09G17890 I 0.000
OPUNC09G15260 Oryza punctata OPUNC09G15260 I 0.000
OPUNC09G15280 Oryza punctata OPUNC09G15280 I 0.000
ORGLA08G0220100 Oryza glaberrima ORGLA08G0220100 I 0.000
ORGLA08G0220200 Oryza glaberrima ORGLA08G0220200 N 0.000
ORGLA09G0133000 Oryza glaberrima ORGLA09G0133000 N 0.000
ORGLA09G0133100 Oryza glaberrima ORGLA09G0133100 I 0.000
ORUFI09G18190 Oryza rufipogon ORUFI09G18190 N 0.000
ORUFI09G18200 Oryza rufipogon ORUFI09G18200 I 0.000
DREB1H Oryza sativa OS09G0522100 I 0.000
Pavir.Ba01281 Panicum virgatum Pavir.Ba01281 I 0.000
Pavir.Fa00114 Panicum virgatum Pavir.Fa00114 N 0.000
Pavir.J03892 Panicum virgatum Pavir.J03892 I 0.000
Pavir.J03893 Panicum virgatum Pavir.J03893 I 0.000
Pavir.J27101 Panicum virgatum Pavir.J27101 I 0.000
Pavir.J32829 Panicum virgatum Pavir.J32829 N 0.000
Sb02g030320 Sorghum bicolor Sb02g030320 I 0.000
Sb02g030330 Sorghum bicolor Sb02g030330 I 0.000
Sb02g030340 Sorghum bicolor Sb02g030340 I 0.000
Sb05g006275 Sorghum bicolor Sb05g006275 I 0.000
Si031001m.g Setaria italica Si031001m.g I 0.000
Traes_5BL_5299B6B33 Triticum aestivum Traes_5BL_5299B6B33 N 0.000
Traes_5BL_D16B19610 Triticum aestivum Traes_5BL_D16B19610 I 0.000