IRX5 (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000176842 T209912_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRX5
M03222_2.00		 Homo sapiens
NDACAYRACAHN
NDTGTYRTGTHN		 SELEX
Jolma et al.(2013)
IRX5_1		 (Direct) (Direct)
IRX5
M05315_2.00		 Homo sapiens
NBDTGTHNDACAYVN
NBRTGTHNDACAHVN		 SELEX
Yin et al.(2017)
IRX5_eDBD_HT-SELEX		 (Direct) (Direct)
IRX5
M05316_2.00		 Homo sapiens
WYRYGHHNHAYRYRY
RYRYRTDNDDCRYRW		 SELEX
Yin et al.(2017)
IRX5_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irx2
M00386_2.00 		Mus musculus
NNDACAHNN
NNDTGTHNN		 PBM
Berger et al.(2008)
Irx2_0900 		0.867 1.000
Irx5
M00455_2.00 		Mus musculus
NNNDACAHN
NDTGTHNNN		 PBM
Berger et al.(2008)
Irx5_2385 		0.867 1.000
IRX2
M03212_2.00 		Homo sapiens
NDACAYRACAHN
NDTGTYRTGTHN		 SELEX
Jolma et al.(2013)
IRX2_1 		0.867 1.000
ara
M06518_2.00 		Drosophila melanogaster
WWACA
TGTWW		 B1H
Mathelier et al.(2014)
MA0210.1 		0.815 0.930
ara
M06313_2.00 		Drosophila melanogaster
TGTWWWNN
NNWWWACA		 B1H
Zhu et al.(2011)
Ara_Cell_FBgn0015904 		0.815 0.930
ara
M06314_2.00 		Drosophila melanogaster
DWWACA
TGTWWH		 B1H
Zhu et al.(2011)
Ara_SOLEXA_FBgn0015904 		0.815 0.930
caup
M06519_2.00 		Drosophila melanogaster
WAACA
TGTTW		 B1H
Mathelier et al.(2014)
MA0217.1 		0.806 0.877
caup
M06315_2.00 		Drosophila melanogaster
HWDWAACA
TGTTWHWD		 B1H
Zhu et al.(2011)
Caup_Cell_FBgn0015919 		0.806 0.877
caup
M06316_2.00 		Drosophila melanogaster
NDDACA
TGTHHN		 B1H
Zhu et al.(2011)
Caup_SOLEXA_FBgn0015919 		0.806 0.877
Irx4
M00416_2.00 		Mus musculus
NNNDAMAH
DTKTHNNN		 PBM
Berger et al.(2008)
Irx4_2242 		0.780 0.877
Irx6
M00456_2.00 		Mus musculus
NNDAHWN
NWDTHNN		 PBM
Berger et al.(2008)
Irx6_2623 		0.780 0.860
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000316250 Homeodomain 114 173
ENSP00000378132 Homeodomain 114 173
ENSP00000453725 Homeodomain 48 107

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

388 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
29589.m001269 Ricinus communis 29589.m001269 N
AMTR_s00140p00061590 Amborella trichopoda AMTR_s00140p00061590 N
Aquca_009_01096 Aquilegia coerulea Aquca_009_01096 N
BGIOSGA015622 Oryza indica BGIOSGA015622 N
BGIOSGA026480 Oryza indica BGIOSGA026480 N
BRADI3G12490 Brachypodium distachyon BRADI3G12490 N
cassava27114.m1 Manihot esculenta cassava27114.m1 N
cassava28521.m1 Manihot esculenta cassava28521.m1 N
Ca_07000 Cicer arietinum Ca_07000 N
chr3.CM0070.360.nc Lotus japonicus chr3.CM0070.360.nc N
Ciclev10029807m.g Citrus clementina Ciclev10029807m.g N
Ciclev10029984m.g Citrus clementina Ciclev10029984m.g N
Cla001892 Citrullus lanatus Cla001892 N
Cucsa.200410 Cucumis sativus Cucsa.200410 N
Eucgr.B03926 Eucalyptus grandis Eucgr.B03926 N
Eucgr.J00391 Eucalyptus grandis Eucgr.J00391 N
gene01102-v1.0-hybrid Fragaria vesca gene01102-v1.0-hybrid N
GLYMA11G19810 Glycine max GLYMA11G19810 N
GLYMA12G08680 Glycine max GLYMA12G08680 N
GLYMA12G30285 Glycine max GLYMA12G30285 N
GLYMA13G39610 Glycine max GLYMA13G39610 N
Gorai.006G104700 Gossypium raimondii Gorai.006G104700 N
Gorai.009G090000 Gossypium raimondii Gorai.009G090000 N
GSMUA_Achr11G02230_001 Musa acuminata GSMUA_Achr11G02230_001 N
GSMUA_Achr1G15330_001 Musa acuminata GSMUA_Achr1G15330_001 N
LPERR08G20460 Leersia perrieri LPERR08G20460 N
MDP0000224892 Malus domestica MDP0000224892 N
MDP0000610922 Malus domestica MDP0000610922 N
mgf025993m Mimulus guttatus mgf025993m N
OB08G30610 Oryza brachyantha OB08G30610 N
OBART04G02230 Oryza barthii OBART04G02230 N
OGLUM04G01880 Oryza glumaepatula OGLUM04G01880 N
OGLUM08G25260 Oryza glumaepatula OGLUM08G25260 N
OLONG_023180 Oryza longistaminata OLONG_023180 N
OMERI04G02190 Oryza meridionalis OMERI04G02190 N
OMERI08G18590 Oryza meridionalis OMERI08G18590 N
ONIVA08G18580 Oryza nivara ONIVA08G18580 N
OPUNC04G02200 Oryza punctata OPUNC04G02200 N
OPUNC08G21710 Oryza punctata OPUNC08G21710 N
orange1.1g042026m.g Citrus sinensis orange1.1g042026m.g N
orange1.1g044007m.g Citrus sinensis orange1.1g044007m.g N
ORGLA04G0016600 Oryza glaberrima ORGLA04G0016600 N
ORGLA08G0191700 Oryza glaberrima ORGLA08G0191700 N
ORUFI04G02970 Oryza rufipogon ORUFI04G02970 N
ORUFI08G26260 Oryza rufipogon ORUFI08G26260 N
OS04G0165200 Oryza sativa OS04G0165200 N
OS08G0562300 Oryza sativa OS08G0562300 N
Pavir.Fa00049 Panicum virgatum Pavir.Fa00049 N
Pavir.Fb02219 Panicum virgatum Pavir.Fb02219 N
PGSC0003DMG400000419 Solanum tuberosum PGSC0003DMG400000419 N
Pm001162 Prunus mume Pm001162 N
POPTR_0004s22670 Populus trichocarpa POPTR_0004s22670 N
PRUPE_ppa019036mg Prunus persica PRUPE_ppa019036mg N
SapurV1A.0360s0140 Salix purpurea SapurV1A.0360s0140 N
Sb07g023890 Sorghum bicolor Sb07g023890 N
Si013894m.g Setaria italica Si013894m.g N
TCM_041585 Theobroma cacao TCM_041585 N
TRIUR3_12142 Triticum urartu TRIUR3_12142 N
VIT_06s0061g00780 Vitis vinifera VIT_06s0061g00780 N