CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

MESCA007508 *(Megaselia scalaris)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00046 (Homeobox)	IPR001356	MESCA007508	T220568_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
achi M03860_2.00	Drosophila melanogaster	TGACAD	HTGTCA	SELEX Nitta et al.(2015) achi_1	0.815	0.800
achi M03861_2.00	Drosophila melanogaster	TGACAGMTGTCA	TGACAKCTGTCA	SELEX Nitta et al.(2015) achi_2	0.815	0.800
achi M03862_2.00	Drosophila melanogaster	TGACAGNNNNNNYGTCA	TGACRNNNNNNCTGTCA	SELEX Nitta et al.(2015) achi_3	0.815	0.800
vis M03859_2.00	Drosophila melanogaster	TGACAS	STGTCA	SELEX Nitta et al.(2015) vis_1	0.815	0.800
vis M06534_2.00	Drosophila melanogaster	TGACAB	BTGTCA	B1H Mathelier et al.(2014) MA0252.1	0.815	0.800
achi M06535_2.00	Drosophila melanogaster	TGACAG	CTGTCA	B1H Mathelier et al.(2014) MA0207.1	0.815	0.800
achi M06345_2.00	Drosophila melanogaster	TGTCADW	WHTGACA	B1H Zhu et al.(2011) Achi_Cell_FBgn0033749	0.815	0.800
achi M06346_2.00	Drosophila melanogaster	HTGACA	TGTCAD	B1H Zhu et al.(2011) Achi_SOLEXA_FBgn0033749	0.815	0.800
vis M06343_2.00	Drosophila melanogaster	TGTCA	TGACA	B1H Zhu et al.(2011) Vis_Cell_FBgn0033748	0.815	0.800
vis M06344_2.00	Drosophila melanogaster	TGTCAD	HTGACA	B1H Zhu et al.(2011) Vis_SOLEXA_FBgn0033748	0.815	0.800
Tgif2 M00521_2.00	Mus musculus	NNTGACANNN	NNNTGTCANN	PBM Berger et al.(2008) Tgif2_3451	0.794	0.727
TGIF2 M03123_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) TGIF2_1	0.794	0.727
TGIF2 M05032_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2_eDBD_HT-SELEX	0.794	0.727
TGIF2 M05034_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Yin et al.(2017) TGIF2_FL_HT-SELEX	0.794	0.727
TGIF2 M05033_2.00	Homo sapiens	TGWCABVTGWCA	TGWCABVTGWCA	SELEX Yin et al.(2017) TGIF2_eDBD_Methyl-HT-SELEX	0.794	0.727
TGIF2 M05035_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Yin et al.(2017) TGIF2_FL_Methyl-HT-SELEX	0.794	0.727
Tgif1 M00500_2.00	Mus musculus	NNTGACANNN	NNNTGTCANN	PBM Berger et al.(2008) Tgif1_2342	0.759	0.709
TGIF1 M03223_2.00	Homo sapiens	TGACAGCTGTCA	TGACAGCTGTCA	SELEX Jolma et al.(2013) TGIF1_1	0.759	0.709
TGIF1 M05317_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Yin et al.(2017) TGIF1_eDBD_HT-SELEX	0.759	0.709
TGIF1 M09159_2.00	Homo sapiens	TGACAGS	SCTGTCA	Misc Kulakovskiy et al.(2013) TGIF1_HUMAN.H11MO.0.A	0.759	0.709
Tgif1 M09211_2.00	Mus musculus	TGACAGBNV	BNVCTGTCA	Misc Kulakovskiy et al.(2013) TGIF1_MOUSE.H11MO.0.A	0.759	0.709
TGIF1 M10740_2.00	Homo sapiens	WHNTGACARST	ASYTGTCANDW	Transfac Matys et al.(2006) V$TGIF_01	0.759	0.709
TGIF1 M05318_2.00	Homo sapiens	TGACAKVTGTCA	TGACABMTGTCA	SELEX Yin et al.(2017) TGIF1_eDBD_Methyl-HT-SELEX	0.759	0.709
hth M06490_2.00	Drosophila melanogaster	TGACAK	MTGTCA	B1H Mathelier et al.(2014) MA0227.1	0.689	0.618
hth M06252_2.00	Drosophila melanogaster	TGTCA	TGACA	B1H Zhu et al.(2011) Hth_Cell_FBgn0001235	0.689	0.618
hth M06253_2.00	Drosophila melanogaster	NNTGACAD	HTGTCANN	B1H Zhu et al.(2011) hth_SOLEXA_2_FBgn0001235	0.689	0.618
hth M06254_2.00	Drosophila melanogaster	NTGACA	TGTCAN	B1H Zhu et al.(2011) Hth_SOLEXA_FBgn0001235	0.689	0.618
Meis1 M00407_2.00	Mus musculus	NTGACADNN	NNHTGTCAN	PBM Berger et al.(2008) Meis1_2335	0.689	0.600
Meis2 M00437_2.00	Mus musculus	NTGACANNN	NNNTGTCAN	PBM Berger et al.(2008) Mrg1_2246	0.689	0.600
Meis3 M00488_2.00	Mus musculus	NTGACANNN	NNNTGTCAN	PBM Berger et al.(2008) Mrg2_2302	0.689	0.600
MEIS1 M03165_2.00	Homo sapiens	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) MEIS1_1	0.689	0.600
MEIS2 M03147_2.00	Homo sapiens	WTGACAGSTGTCAM	KTGACASCTGTCAW	SELEX Jolma et al.(2013) MEIS2_1	0.689	0.600
MEIS2 M03148_2.00	Homo sapiens	DTGACAGS	SCTGTCAH	SELEX Jolma et al.(2013) MEIS2_2	0.689	0.600
Meis2 M03261_2.00	Mus musculus	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) Meis2_1	0.689	0.600
Meis2 M03262_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Meis2_2	0.689	0.600
Meis3 M03279_2.00	Mus musculus	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) Meis3_1	0.689	0.600
Meis3 M03280_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Meis3_2	0.689	0.600
MEIS2 M02740_2.00	Homo sapiens	TGACASSTGTC	GACASSTGTCA	SELEX Jolma et al.(2010) MEIS2_dimer	0.689	0.600
MEIS2 M02741_2.00	Homo sapiens	GGACAKNT	ANMTGTCC	SELEX Jolma et al.(2010) MEIS2_monomer	0.689	0.600
MEIS2 M05138_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_eDBD_HT-SELEX	0.689	0.600
MEIS2 M05140_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_FL_HT-SELEX	0.689	0.600
MEIS1 M09148_2.00	Homo sapiens	NTGATTDATDDB	VHHATHAATCAN	Misc Kulakovskiy et al.(2013) MEIS1_HUMAN.H11MO.0.A	0.689	0.600
MEIS2 M09143_2.00	Homo sapiens	HTGACAGBTKTBM	KVAMAVCTGTCAD	Misc Kulakovskiy et al.(2013) MEIS2_HUMAN.H11MO.0.B	0.689	0.600
Meis1 M09178_2.00	Mus musculus	NTGATTDATDDB	VHHATHAATCAN	Misc Kulakovskiy et al.(2013) MEIS1_MOUSE.H11MO.0.A	0.689	0.600
Meis2 M09189_2.00	Mus musculus	HTGACAGBTKTBM	KVAMAVCTGTCAD	Misc Kulakovskiy et al.(2013) MEIS2_MOUSE.H11MO.0.B	0.689	0.600
Meis1 M09568_2.00	Mus musculus	VBTGWCASNN	NNSTGWCAVB	Misc Heinz et al.(2010) MastCells-Meis1_GSE48085	0.689	0.600
MEIS1 M10709_2.00	Homo sapiens	NHNTGACAGNDN	NHNCTGTCANDN	Transfac Matys et al.(2006) V$MEIS1_01	0.689	0.600
MEIS1 M10710_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$MEIS1_06	0.689	0.600
MEIS2 M05139_2.00	Homo sapiens	YGACASSYGHCR	YGDCRSSTGTCR	SELEX Yin et al.(2017) MEIS2_eDBD_Methyl-HT-SELEX	0.689	0.600
MEIS2 M05141_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_FL_Methyl-HT-SELEX	0.689	0.600
TGIF2LX M03171_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) TGIF2LX_1	0.661	0.636
TGIF2LX M05191_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LX_eDBD_HT-SELEX	0.661	0.636
TGIF2LX M05193_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) TGIF2LX_FL_HT-SELEX	0.661	0.636
TGIF2LX M05192_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LX_eDBD_Methyl-HT-SELEX	0.661	0.636
TGIF2LX M05194_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) TGIF2LX_FL_Methyl-HT-SELEX	0.661	0.636
TGIF2LY M05313_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LY_eDBD_HT-SELEX	0.661	0.618
TGIF2LY M05314_2.00	Homo sapiens	YGACABVTGTCR	YGACABVTGTCR	SELEX Yin et al.(2017) TGIF2LY_eDBD_Methyl-HT-SELEX	0.661	0.618
unc-62 M02185_2.00	Caenorhabditis elegans	NHDAHANNN	NNNTDTHDN	PBM Weirauch et al.(2014) pTH5781	0.652	0.545
Pknox2 M00468_2.00	Mus musculus	NNNGACRNNN	NNNYGTCNNN	PBM Berger et al.(2008) Pknox2_3077	0.633	0.582
PKNOX2 M03195_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) PKNOX2_1	0.633	0.582
Pknox2 M03270_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Pknox2_1	0.633	0.582
PKNOX2 M05246_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) PKNOX2_eDBD_HT-SELEX	0.633	0.582
PKNOX2 M05247_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) PKNOX2_eDBD_Methyl-HT-SELEX	0.633	0.582
Pknox1 M00399_2.00	Mus musculus	HGACRNNN	NNNYGTCD	PBM Berger et al.(2008) Pknox1_2364	0.633	0.564
PKNOX1 M03178_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) PKNOX1_1	0.633	0.564
PKNOX1 M05206_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) PKNOX1_eDBD_HT-SELEX	0.633	0.564
PKNOX1 M05208_2.00	Homo sapiens	TGACAGCTGTCA	TGACAGCTGTCA	SELEX Yin et al.(2017) PKNOX1_FL_HT-SELEX	0.633	0.564
PKNOX1 M09150_2.00	Homo sapiens	TGABTGRCRGV	BCYGYCAVTCA	Misc Kulakovskiy et al.(2013) PKNX1_HUMAN.H11MO.0.B	0.633	0.564
Pknox1 M09175_2.00	Mus musculus	TGABTGRCRGV	BCYGYCAVTCA	Misc Kulakovskiy et al.(2013) PKNX1_MOUSE.H11MO.0.A	0.633	0.564
PKNOX1 M10712_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PREP1_Q3	0.633	0.564
PKNOX1 M05207_2.00	Homo sapiens	YGWCASSTGWCR	YGWCASSTGWCR	SELEX Yin et al.(2017) PKNOX1_eDBD_Methyl-HT-SELEX	0.633	0.564
PKNOX1 M05209_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) PKNOX1_FL_Methyl-HT-SELEX	0.633	0.564
For this family, TFs with SR scores > 0.599* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
MESCA007508-PA	Homeodomain	42	99	RKRRGNLPNESVKILKSWLFEHRYNAYPSDSEKLQLAQRTNLTILQVCNWFINARRRI

Links
Other Homeodomain family TFs
Other *Megaselia scalaris* TFs

797 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
Aan_R002402	Calypte anna	Aan_R002402	I
Alligator_sinensis_CCG014457.1	Alligator sinensis	Alligator_sinensis_CCG014457.1	I
SP2	Anolis carolinensis	ENSACAG00000006793	I
ENSAMEG00000004772	Ailuropoda melanoleuca	ENSAMEG00000004772	I
ENSAMXG00000018374	Astyanax mexicanus	ENSAMXG00000018374	I
SP2	Bos taurus	ENSBTAG00000013740	I
SP2	Canis familiaris	ENSCAFG00000016812	I
ENSCHOG00000008313	Choloepus hoffmanni	ENSCHOG00000008313	I
SP2	Callithrix jacchus	ENSCJAG00000007713	I
SP2	Cavia porcellus	ENSCPOG00000014943	I
ENSCSAG00000002567	Chlorocebus sabaeus	ENSCSAG00000002567	I
sp2	Danio rerio	ENSDARG00000076763	I
SP2	Equus caballus	ENSECAG00000012859	I
SP2	Erinaceus europaeus	ENSEEUG00000014248	I
SP2	Echinops telfairi	ENSETEG00000009168	I
SP2	Felis catus	ENSFCAG00000009365	I
SP2	Homo sapiens	ENSG00000167182	D
sp2	Gasterosteus aculeatus	ENSGACG00000019811	I
SP2	Gallus gallus	ENSGALG00000000233	I
SP2	Gorilla gorilla	ENSGGOG00000005330	I
ENSGMOG00000007030	Gadus morhua	ENSGMOG00000007030	I
ENSLACG00000006434	Latimeria chalumnae	ENSLACG00000006434	I
SP2	Loxodonta africana	ENSLAFG00000021817	I
ENSLOCG00000013729	Lepisosteus oculatus	ENSLOCG00000013729	I
ENSMICG00000014053	Microcebus murinus	ENSMICG00000014053	I
SP2	Myotis lucifugus	ENSMLUG00000005000	I
SP2	Macaca mulatta	ENSMMUG00000004765	I
SP2	Monodelphis domestica	ENSMODG00000012452	I
ENSMPUG00000015289	Mustela putorius furo	ENSMPUG00000015289	I
Sp2	Mus musculus	ENSMUSG00000018678	D
ENSNLEG00000002058	Nomascus leucogenys	ENSNLEG00000002058	I
ENSOARG00000007752	Ovis aries	ENSOARG00000007752	I
SP2	Oryctolagus cuniculus	ENSOCUG00000027415	I
SP2	Otolemur garnettii	ENSOGAG00000030380	I
ENSONIG00000000117	Oreochromis niloticus	ENSONIG00000000117	I
sp2	Oryzias latipes	ENSORLG00000000102	I
ENSP00000365931	Macaca fascicularis	ENSP00000365931	I
SP2	Procavia capensis	ENSPCAG00000002140	I
ENSPFOG00000013068	Poecilia formosa	ENSPFOG00000013068	I
ENSPPYG00000008885	Pongo abelii	ENSPPYG00000008885	I
SP2	Pan troglodytes	ENSPTRG00000009342	I
SP2	Pteropus vampyrus	ENSPVAG00000004255	I
Sp2	Rattus norvegicus	ENSRNOG00000010492	I
SP2	Sorex araneus	ENSSARG00000003559	I
ENSSHAG00000005633	Sarcophilus harrisii	ENSSHAG00000005633	I
ENSSTOG00000015926	Ictidomys tridecemlineatus	ENSSTOG00000015926	I
sp2	Tetraodon nigroviridis	ENSTNIG00000006290	I
sp2	Takifugu rubripes	ENSTRUG00000007642	I
SP2	Tursiops truncatus	ENSTTRG00000012483	I
ENSXMAG00000014321	Xiphophorus maculatus	ENSXMAG00000014321	I
Myotis_brandtii_SP2_10030436	Myotis brandtii	Myotis_brandtii_SP2_10030436	I
Ogr12593	Ophisaurus gracilis	Ogr12593	I
Pvit_13958	Pogona vitticeps	Pvit_13958	I
sp2	Xenopus tropicalis	XB-GENE-968274	I
sp2.S	Xenopus laevis	XB-GENE-968279	I

MESCA007508 (Megaselia scalaris) Homeodomain

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

797 Related TFs

MESCA007508 **(Megaselia scalaris)
Homeodomain**