CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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NPAS2
(
Homo sapiens
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00010 (HLH)
IPR001092
ENSG00000170485
T034312_2.00
Ensembl (2018-Dec-8)
Link out
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
NPAS2
M04158_2.00
Homo sapiens
NRCACGTGKH
DMCACGTGYN
SELEX
Yin et al.(2017)
NPAS2_eDBD_HT-SELEX
(Direct)
(Direct)
NPAS2
M04159_2.00
Homo sapiens
DVCRCRTGKH
DMCAYGYGBH
SELEX
Yin et al.(2017)
NPAS2_eDBD_Methyl-HT-SELEX
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Npas2
M01731_2.00
Mus musculus
NVCACGTGBN
NVCACGTGBN
PBM
Weirauch et al.(2014)
pTH5457
0.914
1.000
Npas2
M09468_2.00
Mus musculus
VKCACRTGKM
KMCAYGTGMB
Misc
Heinz et al.(2010)
Liver-NPAS2_GSE39860
0.914
1.000
For this family, TFs with SR scores >
0.838
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000338283
bHLH
10
59
KRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKH
ENSP00000388528
bHLH
1
49
XASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKH
ENSP00000395265
bHLH
1
43
SEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKH
ENSP00000397595
bHLH
75
124
KRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKH
Links
Other
bHLH
family TFs
Other
Homo sapiens
TFs
55 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Thhalv10012100m.g
Eutrema salsugineum
Thhalv10012100m.g
I
MTR_0121s0080
Medicago truncatula
MTR_0121s0080
N
MTR_1g108500
Medicago truncatula
MTR_1g108500
N