AAA92050 (Xenopus laevis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 AAA92050 T051314_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TCF3
M02775_2.00 		Homo sapiens
NVCACCTGBN
NVCAGGTGBN		 SELEX
Jolma et al.(2013)
TCF3_1 		0.914 0.962
TCF3
M08710_2.00 		Homo sapiens
VVCASCTGCHN
NDGCAGSTGBB		 Misc
Kulakovskiy et al.(2013)
TFE2_HUMAN.H11MO.0.A 		0.914 0.962
TCF3
M09791_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E12_Q6 		0.914 0.962
TCF3
M09792_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2A_Q6_01 		0.914 0.962
TCF3
M09793_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2A_Q6_02 		0.914 0.962
TCF3
M09794_2.00 		Homo sapiens
VVVVMCACCTGCNBB
VVNGCAGGTGKBBBB		 Transfac
Matys et al.(2006)
V$E47_01 		0.914 0.962
TCF3
M09795_2.00 		Homo sapiens
NNKWRCACCTGYDNNN
NNNHRCAGGTGYWMNN		 Transfac
Matys et al.(2006)
V$E47_02 		0.914 0.962
Tcf3
M09465_2.00 		Mus musculus
ABWTCAAAGS
SCTTTGAWVT		 Misc
Heinz et al.(2010)
mES-Tcf3_GSE11724 		0.886 0.923
Tcf3
M09466_2.00 		Mus musculus
VCAGCTGBNN
NNVCAGCTGB		 Misc
Heinz et al.(2010)
proBcell-E2A_GSE21978 		0.886 0.923
Tcf3
M09886_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E47_05 		0.886 0.923
Tcf12
M01740_2.00 		Mus musculus
NVCAYCTGB
VCAGRTGBN		 PBM
Weirauch et al.(2014)
pTH5071 		0.886 0.904
TCF12
M04137_2.00 		Homo sapiens
VCACSTGB
VCASGTGB		 SELEX
Yin et al.(2017)
TCF12_eDBD_HT-SELEX 		0.886 0.904
Tcf12
M08062_2.00 		Mus musculus
RRCAGCTGNNN
NNNCAGCTGYY		 ChIP-seq
Mathelier et al.(2014)
MA0521.1 		0.886 0.904
TCF12
M07805_2.00 		Homo sapiens
NVDSCAGSTGB
VCASCTGSHBN		 ChIP-seq
Gerstein et al.(2012)
GM12878_TCF12_HudsonAlpha 		0.886 0.904
TCF12
M07806_2.00 		Homo sapiens
VCASCTGB
VCAGSTGB		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_TCF12_HudsonAlpha 		0.886 0.904
TCF12
M08731_2.00 		Homo sapiens
CMCASCTGSH
DSCAGSTGKG		 Misc
Kulakovskiy et al.(2013)
HTF4_HUMAN.H11MO.0.A 		0.886 0.904
Tcf12
M08762_2.00 		Mus musculus
VMCASCTGSH
DSCAGSTGKB		 Misc
Kulakovskiy et al.(2013)
HTF4_MOUSE.H11MO.0.A 		0.886 0.904
TCF12
M09458_2.00 		Homo sapiens
NNVCAGCTGB
VCAGCTGBNN		 Misc
Heinz et al.(2010)
GM12878-Tcf12_GSE32465 		0.886 0.904
TCF12
M09858_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HEB_Q6 		0.886 0.904
TCF12
M09859_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HTF4_Q2 		0.886 0.904
TCF12
M09860_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_01 		0.886 0.904
TCF12
M09861_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_03 		0.886 0.904
TCF12
M09862_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_05 		0.886 0.904
TCF12
M04138_2.00 		Homo sapiens
NCAYCTGN
NCAGRTGN		 SELEX
Yin et al.(2017)
TCF12_eDBD_Methyl-HT-SELEX 		0.886 0.904
Tcf3
M00753_2.00 		Mus musculus
VCACCTGBN
NVCAGGTGB		 PBM
Weirauch et al.(2013)
pTH3866 		0.886 0.827
Tcf3
M01723_2.00 		Mus musculus
NNVCACSTGB
VCASGTGBNN		 PBM
Weirauch et al.(2014)
pTH4580 		0.886 0.827
Tcf3
M00118_2.00 		Mus musculus
VCAYCTGB
VCAGRTGB		 PBM
Badis et al.(2009)
Tcfe2a_3865 		0.886 0.827
Tcf4
M01750_2.00 		Mus musculus
VCAGVTGBN
NVCABCTGB		 PBM
Weirauch et al.(2014)
pTH5101 		0.884 0.865
TCF4
M02807_2.00 		Homo sapiens
HRCACCTGBN
NVCAGGTGYD		 SELEX
Jolma et al.(2013)
TCF4_1 		0.884 0.865
TCF4
M02808_2.00 		Homo sapiens
NVCACCTBBN
NVVAGGTGBN		 SELEX
Jolma et al.(2013)
TCF4_2 		0.884 0.865
TCF4
M02728_2.00 		Homo sapiens
RCACCTG
CAGGTGY		 SELEX
Jolma et al.(2010)
TCF4_dimer 		0.884 0.865
TCF4
M04214_2.00 		Homo sapiens
VCACCTGB
VCAGGTGB		 SELEX
Yin et al.(2017)
TCF4_eDBD_HT-SELEX 		0.884 0.865
Tcf4
M08775_2.00 		Mus musculus
HRCACCTGB
VCAGGTGYD		 Misc
Kulakovskiy et al.(2013)
ITF2_MOUSE.H11MO.0.B 		0.884 0.865
TCF4
M09461_2.00 		Homo sapiens
ASWTCAAAGRVN
NBYCTTTGAWST		 Misc
Heinz et al.(2010)
Hct116-Tcf4_SRA012054 		0.884 0.865
TCF4
M04215_2.00 		Homo sapiens
VCACCTGN
NCAGGTGB		 SELEX
Yin et al.(2017)
TCF4_eDBD_Methyl-HT-SELEX 		0.884 0.865
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AAA92050 bHLH 53 106

Links

Other bHLH family TFs
Other Xenopus laevis TFs

208 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
IRF8 Homo sapiens ENSG00000140968 D
Irf8 Mus musculus ENSMUSG00000041515 D
ENSPPYG00000007620 Pongo abelii ENSPPYG00000007620 I
irf4a Tetraodon nigroviridis ENSTNIG00000005370 I
ENSTGUG00000006609 Taeniopygia guttata ENSTGUG00000006609 I
ENSSSCG00000023184 Sus scrofa ENSSSCG00000023184 I
ENSSSCG00000022547 Sus scrofa ENSSSCG00000022547 I
Irf8 Rattus norvegicus ENSRNOG00000017869 I
IRF8 Pan troglodytes ENSPTRG00000008435 I
ENSPSIG00000003518 Pelodiscus sinensis ENSPSIG00000003518 I
irf8 Tetraodon nigroviridis ENSTNIG00000009283 I
ENSPFOG00000017639 Poecilia formosa ENSPFOG00000017639 I
ENSPFOG00000015506 Poecilia formosa ENSPFOG00000015506 I
IRF8 Procavia capensis ENSPCAG00000004460 I
ENSPANG00000024770 Papio anubis ENSPANG00000024770 I
irf8 Oryzias latipes ENSORLG00000018216 I
irf4a Oryzias latipes ENSORLG00000017242 I
IRF8 Ochotona princeps ENSOPRG00000002139 I
ENSAMXG00000002697 Astyanax mexicanus ENSAMXG00000002697 I
irf10 Tetraodon nigroviridis ENSTNIG00000012613 I
irf10 Takifugu rubripes ENSTRUG00000002917 I
irf8 Takifugu rubripes ENSTRUG00000018213 I
IRF4 Tursiops truncatus ENSTTRG00000001849 I
IRF8 Tursiops truncatus ENSTTRG00000016024 I
ENSXMAG00000017015 Xiphophorus maculatus ENSXMAG00000017015 I
Aan_R015695 Calypte anna Aan_R015695 I
Afo_R010468 Aptenodytes forsteri Afo_R010468 I
ENSP00000268638-D1 Bos grunniens ENSP00000268638-D1 I
ENSP00000268638 Macaca fascicularis ENSP00000268638 I
Gfo_R000501 Geospiza fortis Gfo_R000501 I
Gfo_R005312 Geospiza fortis Gfo_R005312 I
irf10 Xenopus tropicalis XB-GENE-1033046 I
irf4 Xenopus tropicalis XB-GENE-988321 I
XP_002934991 Xenopus tropicalis XP_002934991 I
IRF8 Gallus gallus ENSGALG00000005757 I
IRF8 Anolis carolinensis ENSACAG00000005409 I
ENSAMXG00000003452 Astyanax mexicanus ENSAMXG00000003452 I
ENSAMXG00000006093 Astyanax mexicanus ENSAMXG00000006093 I
ENSAMXG00000016370 Astyanax mexicanus ENSAMXG00000016370 I
IRF8 Bos taurus ENSBTAG00000017824 I
ENSCAFG00000007099 Canis familiaris ENSCAFG00000007099 I
ENSCSAG00000003142 Chlorocebus sabaeus ENSCSAG00000003142 I
IRF8 Equus caballus ENSECAG00000015449 I
IRF8 Erinaceus europaeus ENSEEUG00000002644 I
ENSFALG00000005506 Ficedula albicollis ENSFALG00000005506 I
irf10 Gasterosteus aculeatus ENSGACG00000015123 I
irf8 Gasterosteus aculeatus ENSGACG00000015958 I
ENSONIG00000009637 Oreochromis niloticus ENSONIG00000009637 I
IRF8 Gorilla gorilla ENSGGOG00000028251 I
ENSLACG00000005859 Latimeria chalumnae ENSLACG00000005859 I
ENSLACG00000007228 Latimeria chalumnae ENSLACG00000007228 I
IRF8 Loxodonta africana ENSLAFG00000010973 I
ENSLOCG00000001013 Lepisosteus oculatus ENSLOCG00000001013 I
ENSLOCG00000003532 Lepisosteus oculatus ENSLOCG00000003532 I
IRF8 Macaca mulatta ENSMMUG00000008125 I
ENSMODG00000019483 Monodelphis domestica ENSMODG00000019483 I
ENSMPUG00000008641 Mustela putorius furo ENSMPUG00000008641 I
ENSONIG00000005631 Oreochromis niloticus ENSONIG00000005631 I
ENSNLEG00000011429 Nomascus leucogenys ENSNLEG00000011429 I
IRF8 Otolemur garnettii ENSOGAG00000009262 I
IRF8 Ornithorhynchus anatinus ENSOANG00000003741 I
ENSOARG00000011513 Ovis aries ENSOARG00000011513 I
irf10 Oryzias latipes ENSORLG00000011745 N
Ogr04948 Ophisaurus gracilis Ogr04948 N
Myotis_brandtii_IRF4_10023767 Myotis brandtii Myotis_brandtii_IRF4_10023767 N
ENSBTAG00000031214 Bos taurus ENSBTAG00000031214 N
ENSPFOG00000009490 Poecilia formosa ENSPFOG00000009490 N
Alligator_sinensis_CCG000346.1 Alligator sinensis Alligator_sinensis_CCG000346.1 N
ENSDNOG00000030863 Dasypus novemcinctus ENSDNOG00000030863 N
ENSGMOG00000002737 Gadus morhua ENSGMOG00000002737 N