CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

KLF4 *(Pan troglodytes)* C2H2 ZF
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00096 (zf-C2H2)	IPR007087	ENSPTRG00000021230	T108219_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
KLF4 M04463_2.00	Homo sapiens	NVCCACRCCCH	DGGGYGTGGBN	SELEX Yin et al.(2017) KLF4_eDBD_HT-SELEX	0.827	1.000
KLF4 M08091_2.00	Homo sapiens	MCACACCCWNN	NNWGGGTGTGK	ChIP-seq Mathelier et al.(2014) MA0039.3	0.827	1.000
Klf4 M08021_2.00	Mus musculus	VRCCMCRCCCH	DGGGYGKGGYB	ChIP-seq Chen et al.(2011) SRP000217_Klf4	0.827	1.000
KLF4 M08243_2.00	Homo sapiens	RCCMCRCCCH	DGGGYGKGGY	ChIP-seq Najafabadi et al.(2015b) KLF14	0.827	1.000
KLF4 M08894_2.00	Homo sapiens	RCCMCRCCCH	DGGGYGKGGY	Misc Kulakovskiy et al.(2013) KLF4_HUMAN.H11MO.0.A	0.827	1.000
Klf4 M08964_2.00	Mus musculus	GCCMCRCCCWBYBBN	NVVRVWGGGYGKGGC	Misc Kulakovskiy et al.(2013) KLF4_MOUSE.H11MO.0.A	0.827	1.000
KLF4 M10217_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$GKLF_02	0.827	1.000
KLF4 M10218_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$GKLF_Q3_01	0.827	1.000
KLF4 M10219_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$GKLF_Q3	0.827	1.000
KLF4 M10220_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$GKLF_Q4	0.827	1.000
KLF4 M04464_2.00	Homo sapiens	NVCCMCRCCCN	NGGGYGKGGBN	SELEX Yin et al.(2017) KLF4_eDBD_Methyl-HT-SELEX	0.827	1.000
KLF2 M04455_2.00	Homo sapiens	NVCCMCRCCCH	DGGGYGKGGBN	SELEX Yin et al.(2017) KLF2_eDBD_HT-SELEX	0.813	0.942
KLF2 M10210_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$LKLF_Q3	0.813	0.942
KLF2 M10211_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$LKLF_Q6	0.813	0.942
KLF2 M04456_2.00	Homo sapiens	NVCCMCRCCCN	NGGGYGKGGBN	SELEX Yin et al.(2017) KLF2_eDBD_Methyl-HT-SELEX	0.813	0.942
KLF1 M00226_2.00	Homo sapiens	CMCGCCCM	KGGGCGKG	PBM Barrera et al.(2016) KLF1_REF	0.784	0.884
KLF1 M08293_2.00	Homo sapiens	NVNNNRCCMCRCCCH	DGGGYGKGGYNNNBN	ChIP-seq Schmitges et al.(2016) Q13351.MEME	0.784	0.884
KLF1 M08871_2.00	Homo sapiens	SVNDGCCMCRCCCH	DGGGYGKGGCHNBS	Misc Kulakovskiy et al.(2013) KLF1_HUMAN.H11MO.0.A	0.784	0.884
KLF1 M10163_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$EKLF_Q5_01	0.784	0.884
KLF1 M10164_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$EKLF_Q5	0.784	0.884
KLF1 M00224_2.00	Homo sapiens	YMCGCCCH	DGGGCGKR	PBM Barrera et al.(2016) KLF1_H299Y	0.784	0.870
KLF5 M04410_2.00	Homo sapiens	NMCACRCCCH	DGGGYGTGKN	SELEX Yin et al.(2017) KLF5_eDBD_HT-SELEX	0.784	0.841
KLF5 M08086_2.00	Homo sapiens	BCCMCDCCCH	DGGGHGKGGV	ChIP-seq Mathelier et al.(2014) MA0599.1	0.784	0.841
KLF5 M08868_2.00	Homo sapiens	NHVNRCCMCDCCCH	DGGGHGKGGYNBDN	Misc Kulakovskiy et al.(2013) KLF5_HUMAN.H11MO.0.A	0.784	0.841
Klf5 M08965_2.00	Mus musculus	KCCMCDCCCHBBBCH	DGVVVDGGGHGKGGM	Misc Kulakovskiy et al.(2013) KLF5_MOUSE.H11MO.0.A	0.784	0.841
KLF5 M09502_2.00	Homo sapiens	GCCMCRCCCH	DGGGYGKGGC	Misc Heinz et al.(2010) LoVo-KLF5_GSE49402	0.784	0.841
KLF5 M10149_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$BTEB2_Q3_01	0.784	0.841
KLF5 M10150_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$BTEB2_Q3	0.784	0.841
KLF5 M04411_2.00	Homo sapiens	NMCACRCCYH	DRGGYGTGKN	SELEX Yin et al.(2017) KLF5_eDBD_Methyl-HT-SELEX	0.784	0.841
KLF3 M04418_2.00	Homo sapiens	RRCCRCGCCCH	DGGGCGYGGYY	SELEX Yin et al.(2017) KLF3_FL_HT-SELEX	0.784	0.826
KLF3 M08876_2.00	Homo sapiens	NSNNVCCMCRCCCHBBBBN	NVVVVDGGGYGKGGBNNSN	Misc Kulakovskiy et al.(2013) KLF3_HUMAN.H11MO.0.B	0.784	0.826
Klf3 M08982_2.00	Mus musculus	NSNNVCCMCRCCCHBBBBN	NVVVVDGGGYGKGGBNNSN	Misc Kulakovskiy et al.(2013) KLF3_MOUSE.H11MO.0.A	0.784	0.826
KLF3 M10172_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$KLF3_Q3_01	0.784	0.826
KLF3 M10173_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$KLF3_Q3	0.784	0.826
KLF3 M04419_2.00	Homo sapiens	DRCCACGCCCH	DGGGCGTGGYH	SELEX Yin et al.(2017) KLF3_FL_Methyl-HT-SELEX_1	0.784	0.826
KLF3 M04420_2.00	Homo sapiens	RRSCGCARCCCN	NGGGYTGCGSYY	SELEX Yin et al.(2017) KLF3_FL_Methyl-HT-SELEX_2	0.784	0.826
Klf1 M08099_2.00	Mus musculus	NRCCACACCCW	WGGGTGTGGYN	ChIP-seq Mathelier et al.(2014) MA0493.1	0.781	0.855
Klf1 M09008_2.00	Mus musculus	MVMNSCCMCRCCCH	DGGGYGKGGSNKBK	Misc Kulakovskiy et al.(2013) KLF1_MOUSE.H11MO.0.A	0.781	0.855
Klf1 M09516_2.00	Mus musculus	DRCCACACCCWN	NWGGGTGTGGYH	Misc Heinz et al.(2010) Erythrocyte-Klf1_GSE20478	0.781	0.855
Klf7 M00134_2.00	Mus musculus	NHHMCRCCCH	DGGGYGKDDN	PBM Badis et al.(2009) Klf7_0974	0.765	0.812
luna M03704_2.00	Drosophila melanogaster	RCCACRCCCH	DGGGYGTGGY	SELEX Nitta et al.(2015) luna_1	0.765	0.812
luna M06163_2.00	Drosophila melanogaster	RRMHMCRCCC	GGGYGKDKYY	B1H Zhu et al.(2011) luna_SANGER_5_FBgn0040765	0.765	0.812
luna M06164_2.00	Drosophila melanogaster	DRCCMCGCCCHNNN	NNNDGGGCGKGGYH	B1H Zhu et al.(2011) luna_SOLEXA_5_FBgn0040765	0.765	0.812
KLF7 M08298_2.00	Homo sapiens	VVCHMCGCCCH	DGGGCGKDGBB	ChIP-seq Schmitges et al.(2016) O75840.MEME	0.765	0.812
KLF6 M04400_2.00	Homo sapiens	NVMCACRCCCH	DGGGYGTGKBN	SELEX Yin et al.(2017) KLF6_eDBD_HT-SELEX	0.765	0.797
KLF6 M08857_2.00	Homo sapiens	BYBYVNBCYMCDCCCYBBN	NVVRGGGHGKRGVNBRVRV	Misc Kulakovskiy et al.(2013) KLF6_HUMAN.H11MO.0.A	0.765	0.797
Klf6 M08962_2.00	Mus musculus	BYBYVNBCYMCDCCCYBBN	NVVRGGGHGKRGVNBRVRV	Misc Kulakovskiy et al.(2013) KLF6_MOUSE.H11MO.0.B	0.765	0.797
KLF6 M10113_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$CPBP_Q6	0.765	0.797
KLF6 M04401_2.00	Homo sapiens	NRCCACGCCCH	DGGGCGTGGYN	SELEX Yin et al.(2017) KLF6_eDBD_Methyl-HT-SELEX	0.765	0.797
Klf12 M00787_2.00	Mus musculus	NNHMCRCCCH	DGGGYGKDNN	PBM Weirauch et al.(2013) pTH0977	0.762	0.812
Klf12 M02937_2.00	Mus musculus	GRCCACGCCCWHHHN	NDDDWGGGCGTGGYC	SELEX Jolma et al.(2013) Klf12_1	0.762	0.812
KLF12 M04430_2.00	Homo sapiens	DRCCACGCCCH	DGGGCGTGGYH	SELEX Yin et al.(2017) KLF12_FL_HT-SELEX	0.762	0.812
KLF12 M08299_2.00	Homo sapiens	SBNVGCCMCGCCCHB	VDGGGCGKGGCBNVS	ChIP-seq Schmitges et al.(2016) Q9Y4X4.MEME	0.762	0.812
KLF12 M08879_2.00	Homo sapiens	GCCCCGCCCYB	VRGGGCGGGGC	Misc Kulakovskiy et al.(2013) KLF12_HUMAN.H11MO.0.C	0.762	0.812
KLF12 M10186_2.00	Homo sapiens	HMYACDG	CHGTRKD	Transfac Matys et al.(2006) V$AP2REP_01	0.762	0.812
KLF12 M04431_2.00	Homo sapiens	RGSCGACGCCCN	NGGGCGTCGSCY	SELEX Yin et al.(2017) KLF12_FL_Methyl-HT-SELEX_1	0.762	0.812
KLF12 M04432_2.00	Homo sapiens	NRCCACGCCCH	DGGGCGTGGYN	SELEX Yin et al.(2017) KLF12_FL_Methyl-HT-SELEX_2	0.762	0.812
dar1 M06171_2.00	Drosophila melanogaster	RMCACACCCWH	DWGGGTGTGKY	B1H Zhu et al.(2011) CG12029_SANGER_10_FBgn0035454	0.758	0.768
dar1 M06172_2.00	Drosophila melanogaster	NNNRCCACRCCCHNN	NNDGGGYGTGGYNNN	B1H Zhu et al.(2011) CG12029_SOLEXA_5_FBgn0035454	0.758	0.768
For this family, TFs with SR scores > 0.755* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSPTRP00000036269	C2H2 ZF	396	420	HTCDYAGCGKTYTKSSHLKAHLRTH
ENSPTRP00000036269	C2H2 ZF	426	450	YHCDWDGCGWKFARSDELTRHYRKH
ENSPTRP00000036269	C2H2 ZF	456	478	FQCQKCDRAFSRSDHLALHMKRH

Links
Other C2H2 ZF family TFs
Other *Pan troglodytes* TFs

668 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
GRMZM2G387485	Zea mays	GRMZM2G387485	N
LPERR06G23780	Leersia perrieri	LPERR06G23780	N
OB06G36080	Oryza brachyantha	OB06G36080	N
OBART06G28330	Oryza barthii	OBART06G28330	N
OGLUM06G29720	Oryza glumaepatula	OGLUM06G29720	N
OLONG_013922	Oryza longistaminata	OLONG_013922	N
ONIVA06G31450	Oryza nivara	ONIVA06G31450	N
ORGLA06G0289000	Oryza glaberrima	ORGLA06G0289000	N
ORUFI06G30250	Oryza rufipogon	ORUFI06G30250	N
Si005834m.g	Setaria italica	Si005834m.g	N
Traes_7AL_153E1A74A	Triticum aestivum	Traes_7AL_153E1A74A	N
Pavir.Db00082	Panicum virgatum	Pavir.Db00082	N
Pavir.J04848	Panicum virgatum	Pavir.J04848	N

KLF4 (Pan troglodytes) C2H2 ZF

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

668 Related TFs

KLF4 **(Pan troglodytes)
C2H2 ZF**