irf4a (Danio rerio)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSDARG00000006560 T244009_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF4
M03334_2.00 		Homo sapiens
HCGAAACCGAAACYW
WRGTTTCGGTTTCGD		 SELEX
Jolma et al.(2013)
IRF4_1 		0.914 0.914
IRF4
M05539_2.00 		Homo sapiens
NYGAAACYGAAACYN
NRGTTTCRGTTTCRN		 SELEX
Yin et al.(2017)
IRF4_FL_HT-SELEX 		0.914 0.914
IRF4
M07978_2.00 		Homo sapiens
DNDVNNGWWVTGAVWVWN
NWBWBTCABWWCNNBHNH		 ChIP-seq
Gerstein et al.(2012)
GM12878_IRF4_HudsonAlpha 		0.914 0.914
IRF4
M09235_2.00 		Homo sapiens
NDWDRRGGAASTGARAVH
DBTYTCASTTCCYYHWHN		 Misc
Kulakovskiy et al.(2013)
IRF4_HUMAN.H11MO.0.A 		0.914 0.914
IRF4
M09595_2.00 		Homo sapiens
HNYGAAASYD
HRSTTTCRND		 Misc
Heinz et al.(2010)
GM12878-IRF4_GSE32465 		0.914 0.914
IRF4
M10885_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_07 		0.914 0.914
IRF4
M10886_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_08 		0.914 0.914
IRF4
M10887_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q5_01 		0.914 0.914
IRF4
M10888_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q5 		0.914 0.914
IRF4
M10889_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q6 		0.914 0.914
IRF4
M05540_2.00 		Homo sapiens
NYGAAASYGAWASHN
NDSTWTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF4_FL_Methyl-HT-SELEX 		0.914 0.914
Irf4
M00175_2.00 		Mus musculus
NNNYGAWASN
NSTWTCRNNN		 PBM
Badis et al.(2009)
Irf4_3476 		0.905 0.905
Irf4
M09243_2.00 		Mus musculus
NDAWVVRGAASTGARAVH
DBTYTCASTTCYBBWTHN		 Misc
Kulakovskiy et al.(2013)
IRF4_MOUSE.H11MO.0.A 		0.905 0.905
Irf8
M09246_2.00 		Mus musculus
NDDDRRGGAASTGAAASYNN
NNRSTTTCASTTCCYYHHHN		 Misc
Kulakovskiy et al.(2013)
IRF8_MOUSE.H11MO.0.A 		0.781 0.781
IRF8
M03335_2.00 		Homo sapiens
HCGAAACYGAAACY
RGTTTCRGTTTCGD		 SELEX
Jolma et al.(2013)
IRF8_1 		0.762 0.762
IRF8
M03336_2.00 		Homo sapiens
HCGAAACCGAAACT
AGTTTCGGTTTCGD		 SELEX
Jolma et al.(2013)
IRF8_2 		0.762 0.762
IRF8
M05541_2.00 		Homo sapiens
NYGAAASYGAAASHN
NDSTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_eDBD_HT-SELEX 		0.762 0.762
IRF8
M05543_2.00 		Homo sapiens
NCGAAACYGAAACYN
NRGTTTCRGTTTCGN		 SELEX
Yin et al.(2017)
IRF8_FL_HT-SELEX 		0.762 0.762
IRF8
M09236_2.00 		Homo sapiens
NDDDRRGGAASTGAAASYNN
NNRSTTTCASTTCCYYHHHN		 Misc
Kulakovskiy et al.(2013)
IRF8_HUMAN.H11MO.0.B 		0.762 0.762
IRF8
M10890_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ICSBP_Q6 		0.762 0.762
IRF8
M10891_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF8_Q6 		0.762 0.762
IRF8
M05542_2.00 		Homo sapiens
NYGAAASYGAAASYN
NRSTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_eDBD_Methyl-HT-SELEX 		0.762 0.762
IRF8
M05544_2.00 		Homo sapiens
NYGAAASYGAAACYD
HRGTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_FL_Methyl-HT-SELEX 		0.762 0.762
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000005897 IRF 17 122

Links

Other IRF family TFs
Other Danio rerio TFs

156 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
IRF4 Homo sapiens ENSG00000137265 D 0.914
IRF8 Homo sapiens ENSG00000140968 D 0.762
Irf4 Mus musculus ENSMUSG00000021356 D 0.905
Irf8 Mus musculus ENSMUSG00000041515 D 0.781
IRF8 Anolis carolinensis ENSACAG00000005409 I 0.800
IRF4 Anolis carolinensis ENSACAG00000017711 I 0.924
ENSAMEG00000005976 Ailuropoda melanoleuca ENSAMEG00000005976 I 0.914
ENSAMEG00000018268 Ailuropoda melanoleuca ENSAMEG00000018268 I 0.779
ENSAMXG00000002697 Astyanax mexicanus ENSAMXG00000002697 I 0.762
ENSAMXG00000003452 Astyanax mexicanus ENSAMXG00000003452 I 0.743
ENSAMXG00000004911 Astyanax mexicanus ENSAMXG00000004911 I 0.705
ENSAMXG00000006093 Astyanax mexicanus ENSAMXG00000006093 I 0.914
ENSAMXG00000012775 Astyanax mexicanus ENSAMXG00000012775 I 0.867
ENSAMXG00000016370 Astyanax mexicanus ENSAMXG00000016370 I 0.971
ENSAPLG00000014646 Anas platyrhynchos ENSAPLG00000014646 I 0.924
IRF4 Bos taurus ENSBTAG00000002929 I 0.914
IRF8 Bos taurus ENSBTAG00000017824 I 0.781
ENSCAFG00000007099 Canis familiaris ENSCAFG00000007099 I 0.705
IRF8 Canis familiaris ENSCAFG00000019919 I 0.779
IRF8 Callithrix jacchus ENSCJAG00000017331 I 0.771
IRF4 Callithrix jacchus ENSCJAG00000019524 I 0.914
IRF4 Cavia porcellus ENSCPOG00000003562 I 0.914
ENSCPOG00000027266 Cavia porcellus ENSCPOG00000027266 I 0.760
ENSCSAG00000003142 Chlorocebus sabaeus ENSCSAG00000003142 I 0.771
ENSCSAG00000007164 Chlorocebus sabaeus ENSCSAG00000007164 I 0.914
irf9 Danio rerio ENSDARG00000016457 I 0.702
irf10 Danio rerio ENSDARG00000027658 I 0.752
irf4b Danio rerio ENSDARG00000055374 I 0.914
irf8 Danio rerio ENSDARG00000056407 I 0.724
IRF8 Dasypus novemcinctus ENSDNOG00000038898 I 0.771
Irf4 Dipodomys ordii ENSDORG00000014895 I 0.914
IRF4 Equus caballus ENSECAG00000016808 I 0.914
IRF8 Erinaceus europaeus ENSEEUG00000002644 I 0.762
IRF4 Erinaceus europaeus ENSEEUG00000007703 I 0.848
IRF4 Echinops telfairi ENSETEG00000018472 I 0.914
ENSFALG00000005506 Ficedula albicollis ENSFALG00000005506 I 0.752
ENSFALG00000006647 Ficedula albicollis ENSFALG00000006647 I 0.769
ENSFALG00000013071 Ficedula albicollis ENSFALG00000013071 I 0.924
IRF8 Felis catus ENSFCAG00000007615 I 0.779
IRF4 Felis catus ENSFCAG00000022941 I 0.914
ENSFCAG00000029870 Felis catus ENSFCAG00000029870 I 0.714
irf4b Gasterosteus aculeatus ENSGACG00000004966 I 0.895
irf8 Gasterosteus aculeatus ENSGACG00000015958 I 0.743
irf4a Gasterosteus aculeatus ENSGACG00000016461 I 0.886
IRF8 Gallus gallus ENSGALG00000005757 I 0.771
ENSGALG00000006448 Gallus gallus ENSGALG00000006448 I 0.743
ENSGALG00000012830 Gallus gallus ENSGALG00000012830 I 0.924
IRF4 Gorilla gorilla ENSGGOG00000012342 I 0.914
IRF8 Gorilla gorilla ENSGGOG00000028251 I 0.771
ENSGMOG00000003945 Gadus morhua ENSGMOG00000003945 I 0.750
ENSGMOG00000005047 Gadus morhua ENSGMOG00000005047 I 0.895
ENSGMOG00000016994 Gadus morhua ENSGMOG00000016994 I 0.886
ENSLACG00000004633 Latimeria chalumnae ENSLACG00000004633 I 0.731
ENSLACG00000005859 Latimeria chalumnae ENSLACG00000005859 I 0.762
ENSLACG00000007228 Latimeria chalumnae ENSLACG00000007228 I 0.790
IRF8 Loxodonta africana ENSLAFG00000010973 I 0.771
IRF4 Loxodonta africana ENSLAFG00000017235 I 0.914
ENSLAFG00000030530 Loxodonta africana ENSLAFG00000030530 I 0.724
ENSLOCG00000001013 Lepisosteus oculatus ENSLOCG00000001013 I 0.752
ENSLOCG00000003532 Lepisosteus oculatus ENSLOCG00000003532 I 0.790
ENSLOCG00000013008 Lepisosteus oculatus ENSLOCG00000013008 I 0.933
ENSMEUG00000002440 Macropus eugenii ENSMEUG00000002440 I 0.905
IRF8 Myotis lucifugus ENSMLUG00000005109 I 0.779
IRF4 Myotis lucifugus ENSMLUG00000010058 I 0.914
IRF8 Macaca mulatta ENSMMUG00000008125 I 0.771
IRF4 Macaca mulatta ENSMMUG00000018513 I 0.914
IRF8 Monodelphis domestica ENSMODG00000004572 I 0.769
IRF4 Monodelphis domestica ENSMODG00000008383 I 0.905
ENSMODG00000019483 Monodelphis domestica ENSMODG00000019483 I 0.714
ENSMPUG00000007848 Mustela putorius furo ENSMPUG00000007848 I 0.914
ENSMPUG00000008641 Mustela putorius furo ENSMPUG00000008641 I 0.762
ENSNLEG00000010631 Nomascus leucogenys ENSNLEG00000010631 I 0.914
ENSNLEG00000011429 Nomascus leucogenys ENSNLEG00000011429 I 0.771
IRF8 Ornithorhynchus anatinus ENSOANG00000003741 I 0.781
IRF4 Ornithorhynchus anatinus ENSOANG00000006326 I 0.885
ENSOARG00000003822 Ovis aries ENSOARG00000003822 I 0.914
ENSOARG00000011513 Ovis aries ENSOARG00000011513 I 0.781
IRF8 Oryctolagus cuniculus ENSOCUG00000000536 I 0.779
IRF4 Oryctolagus cuniculus ENSOCUG00000009374 I 0.895
IRF8 Otolemur garnettii ENSOGAG00000009262 I 0.771
IRF4 Otolemur garnettii ENSOGAG00000014574 I 0.914
ENSONIG00000005631 Oreochromis niloticus ENSONIG00000005631 I 0.743
ENSONIG00000006398 Oreochromis niloticus ENSONIG00000006398 I 0.924
ENSONIG00000009637 Oreochromis niloticus ENSONIG00000009637 I 0.905
ENSONIG00000017148 Oreochromis niloticus ENSONIG00000017148 I 0.724
IRF8 Ochotona princeps ENSOPRG00000002139 I 0.762
IRF4 Ochotona princeps ENSOPRG00000012683 I 0.914
irf4b Oryzias latipes ENSORLG00000012712 I 0.914
irf4a Oryzias latipes ENSORLG00000017242 I 0.895
irf8 Oryzias latipes ENSORLG00000018216 I 0.733
ENSPANG00000024770 Papio anubis ENSPANG00000024770 I 0.771
IRF8 Procavia capensis ENSPCAG00000004460 I 0.771
ENSPFOG00000000657 Poecilia formosa ENSPFOG00000000657 I 0.924
ENSPFOG00000015506 Poecilia formosa ENSPFOG00000015506 I 0.886
ENSPFOG00000017639 Poecilia formosa ENSPFOG00000017639 I 0.733
ENSPPYG00000007620 Pongo abelii ENSPPYG00000007620 I 0.771
ENSPPYG00000016161 Pongo abelii ENSPPYG00000016161 I 0.914
ENSPSIG00000003518 Pelodiscus sinensis ENSPSIG00000003518 I 0.750
ENSPSIG00000011619 Pelodiscus sinensis ENSPSIG00000011619 I 0.914
ENSPSIG00000011788 Pelodiscus sinensis ENSPSIG00000011788 I 0.779
IRF8 Pan troglodytes ENSPTRG00000008435 I 0.771
IRF4 Pan troglodytes ENSPTRG00000017656 I 0.914
IRF8 Pteropus vampyrus ENSPVAG00000003758 I 0.779
IRF4 Pteropus vampyrus ENSPVAG00000005078 I 0.914
Irf8 Rattus norvegicus ENSRNOG00000017869 I 0.762
Irf4 Rattus norvegicus ENSRNOG00000061070 I 0.905
ENSSHAG00000006901 Sarcophilus harrisii ENSSHAG00000006901 I 0.769
ENSSHAG00000015592 Sarcophilus harrisii ENSSHAG00000015592 I 0.905
ENSSTOG00000011470 Ictidomys tridecemlineatus ENSSTOG00000011470 I 0.914
ENSSTOG00000028363 Ictidomys tridecemlineatus ENSSTOG00000028363 I 0.779
IRF4 Tupaia belangeri ENSTBEG00000012240 I 0.914
IRF8 Tupaia belangeri ENSTBEG00000013828 I 0.760
IRF4 Taeniopygia guttata ENSTGUG00000002144 I 0.924
ENSTGUG00000006609 Taeniopygia guttata ENSTGUG00000006609 I 0.752
ENSTNIG00000002469 Tetraodon nigroviridis ENSTNIG00000002469 I 0.730
irf4a Tetraodon nigroviridis ENSTNIG00000005370 I 0.867
irf4b Tetraodon nigroviridis ENSTNIG00000008222 I 0.914
irf8 Tetraodon nigroviridis ENSTNIG00000009283 I 0.724
irf10 Takifugu rubripes ENSTRUG00000002917 I 0.705
irf4b Takifugu rubripes ENSTRUG00000002946 I 0.924
irf4a Takifugu rubripes ENSTRUG00000011568 I 0.848
irf8 Takifugu rubripes ENSTRUG00000018213 I 0.733
IRF4 Tursiops truncatus ENSTTRG00000001849 I 0.905
ENSXMAG00000003082 Xiphophorus maculatus ENSXMAG00000003082 I 0.750
ENSXMAG00000006246 Xiphophorus maculatus ENSXMAG00000006246 I 0.924
ENSXMAG00000017015 Xiphophorus maculatus ENSXMAG00000017015 I 0.886
Aan_R009222 Calypte anna Aan_R009222 I 0.760
Aan_R012662 Calypte anna Aan_R012662 I 0.924
Afo_R010468 Aptenodytes forsteri Afo_R010468 I 0.772
Afo_R011419 Aptenodytes forsteri Afo_R011419 I 0.779
Afo_R014746 Aptenodytes forsteri Afo_R014746 I 0.924
Alligator_sinensis_CCG008430.1 Alligator sinensis Alligator_sinensis_CCG008430.1 I 0.779
Alligator_sinensis_CCG015622.1 Alligator sinensis Alligator_sinensis_CCG015622.1 I 0.924
Brh_R000433 Buceros rhinoceros Brh_R000433 I 0.933
Brh_R009589 Buceros rhinoceros Brh_R009589 I 0.779
Cmyd_10011521 Chelonia mydas Cmyd_10011521 I 0.924
Cmyd_10021085 Chelonia mydas Cmyd_10021085 I 0.779
ENSP00000268638-D1 Bos grunniens ENSP00000268638-D1 I 0.781
ENSP00000268638 Macaca fascicularis ENSP00000268638 I 0.771
ENSP00000370343-D1 Bos grunniens ENSP00000370343-D1 I 0.914
ENSP00000370343 Macaca fascicularis ENSP00000370343 I 0.949
Gfo_R000501 Geospiza fortis Gfo_R000501 I 0.752
Gfo_R003357 Geospiza fortis Gfo_R003357 I 0.924
Myotis_brandtii_Irf4_10020370 Myotis brandtii Myotis_brandtii_Irf4_10020370 I 0.876
Myotis_brandtii_IRF8_10035313 Myotis brandtii Myotis_brandtii_IRF8_10035313 I 0.779
Ogr05775 Ophisaurus gracilis Ogr05775 I 0.924
Ogr08841 Ophisaurus gracilis Ogr08841 I 0.765
Pvit_05673 Pogona vitticeps Pvit_05673 I 0.914
Pvit_16863 Pogona vitticeps Pvit_16863 I 0.790
Tal_R007108 Tyto alba Tal_R007108 I 0.779
Tal_R010571 Tyto alba Tal_R010571 I 0.931
irf8.L Xenopus laevis XB-GENE-985949 I 0.771
irf4 Xenopus tropicalis XB-GENE-988321 I 0.895
ENSBTAG00000031214 Bos taurus ENSBTAG00000031214 N 0.705
ENSBTAP00000012124-D1 Bos grunniens ENSBTAP00000012124-D1 N 0.705
Ogr04948 Ophisaurus gracilis Ogr04948 N 0.705