IRF8 (Equus caballus)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSECAG00000015449 T244043_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF8
M03335_2.00 		Homo sapiens
HCGAAACYGAAACY
RGTTTCRGTTTCGD		 SELEX
Jolma et al.(2013)
IRF8_1 		0.949 0.949
IRF8
M03336_2.00 		Homo sapiens
HCGAAACCGAAACT
AGTTTCGGTTTCGD		 SELEX
Jolma et al.(2013)
IRF8_2 		0.949 0.949
IRF8
M05541_2.00 		Homo sapiens
NYGAAASYGAAASHN
NDSTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_eDBD_HT-SELEX 		0.949 0.949
IRF8
M05543_2.00 		Homo sapiens
NCGAAACYGAAACYN
NRGTTTCRGTTTCGN		 SELEX
Yin et al.(2017)
IRF8_FL_HT-SELEX 		0.949 0.949
IRF8
M09236_2.00 		Homo sapiens
NDDDRRGGAASTGAAASYNN
NNRSTTTCASTTCCYYHHHN		 Misc
Kulakovskiy et al.(2013)
IRF8_HUMAN.H11MO.0.B 		0.949 0.949
Irf8
M09246_2.00 		Mus musculus
NDDDRRGGAASTGAAASYNN
NNRSTTTCASTTCCYYHHHN		 Misc
Kulakovskiy et al.(2013)
IRF8_MOUSE.H11MO.0.A 		0.949 0.949
IRF8
M10890_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ICSBP_Q6 		0.949 0.949
IRF8
M10891_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF8_Q6 		0.949 0.949
IRF8
M05542_2.00 		Homo sapiens
NYGAAASYGAAASYN
NRSTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_eDBD_Methyl-HT-SELEX 		0.949 0.949
IRF8
M05544_2.00 		Homo sapiens
NYGAAASYGAAACYD
HRGTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_FL_Methyl-HT-SELEX 		0.949 0.949
Irf4
M00175_2.00 		Mus musculus
NNNYGAWASN
NSTWTCRNNN		 PBM
Badis et al.(2009)
Irf4_3476 		0.763 0.763
IRF4
M03334_2.00 		Homo sapiens
HCGAAACCGAAACYW
WRGTTTCGGTTTCGD		 SELEX
Jolma et al.(2013)
IRF4_1 		0.763 0.763
IRF4
M05539_2.00 		Homo sapiens
NYGAAACYGAAACYN
NRGTTTCRGTTTCRN		 SELEX
Yin et al.(2017)
IRF4_FL_HT-SELEX 		0.763 0.763
IRF4
M07978_2.00 		Homo sapiens
DNDVNNGWWVTGAVWVWN
NWBWBTCABWWCNNBHNH		 ChIP-seq
Gerstein et al.(2012)
GM12878_IRF4_HudsonAlpha 		0.763 0.763
IRF4
M09235_2.00 		Homo sapiens
NDWDRRGGAASTGARAVH
DBTYTCASTTCCYYHWHN		 Misc
Kulakovskiy et al.(2013)
IRF4_HUMAN.H11MO.0.A 		0.763 0.763
Irf4
M09243_2.00 		Mus musculus
NDAWVVRGAASTGARAVH
DBTYTCASTTCYBBWTHN		 Misc
Kulakovskiy et al.(2013)
IRF4_MOUSE.H11MO.0.A 		0.763 0.763
IRF4
M09595_2.00 		Homo sapiens
HNYGAAASYD
HRSTTTCRND		 Misc
Heinz et al.(2010)
GM12878-IRF4_GSE32465 		0.763 0.763
IRF4
M10885_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_07 		0.763 0.763
IRF4
M10886_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_08 		0.763 0.763
IRF4
M10887_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q5_01 		0.763 0.763
IRF4
M10888_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q5 		0.763 0.763
IRF4
M10889_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q6 		0.763 0.763
IRF4
M05540_2.00 		Homo sapiens
NYGAAASYGAWASHN
NDSTWTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF4_FL_Methyl-HT-SELEX 		0.763 0.763
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSECAP00000013252 IRF 1 59

Links

Other IRF family TFs
Other Equus caballus TFs

47 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Irf4 Mus musculus ENSMUSG00000021356 D 0.763
Irf8 Mus musculus ENSMUSG00000041515 D 0.949
Irf4 Rattus norvegicus ENSRNOG00000061070 I 0.763
ENSPSIG00000003518 Pelodiscus sinensis ENSPSIG00000003518 I 0.750
ENSSSCG00000022547 Sus scrofa ENSSSCG00000022547 I 0.729
ENSSSCG00000023184 Sus scrofa ENSSSCG00000023184 I 0.949
ENSTGUG00000006609 Taeniopygia guttata ENSTGUG00000006609 I 0.746
irf4a Tetraodon nigroviridis ENSTNIG00000005370 I 0.746
irf8 Tetraodon nigroviridis ENSTNIG00000009283 I 0.932
irf4b Takifugu rubripes ENSTRUG00000002946 I 0.763
irf8 Takifugu rubripes ENSTRUG00000018213 I 0.932
ENSTSYG00000006495 Tarsius syrichta ENSTSYG00000006495 I 0.804
IRF8 Tursiops truncatus ENSTTRG00000016024 I 1.000
ENSXMAG00000017015 Xiphophorus maculatus ENSXMAG00000017015 I 0.763
Aan_R015695 Calypte anna Aan_R015695 I 0.789
Afo_R010468 Aptenodytes forsteri Afo_R010468 I 0.807
Cmyd_10009547 Chelonia mydas Cmyd_10009547 I 0.724
ENSP00000268638 Macaca fascicularis ENSP00000268638 I 0.949
ENSP00000370343 Macaca fascicularis ENSP00000370343 I 0.763
Gfo_R005312 Geospiza fortis Gfo_R005312 I 0.789
Ogr05775 Ophisaurus gracilis Ogr05775 I 0.763
Tal_R010571 Tyto alba Tal_R010571 I 0.793
irf8.L Xenopus laevis XB-GENE-985949 I 0.932
XP_002934991 Xenopus tropicalis XP_002934991 I 1.000
ENSNLEG00000011429 Nomascus leucogenys ENSNLEG00000011429 I 0.949
ENSCAFG00000007099 Canis familiaris ENSCAFG00000007099 I 0.712
IRF4 Choloepus hoffmanni ENSCHOG00000012417 I 0.804
ENSCSAG00000003142 Chlorocebus sabaeus ENSCSAG00000003142 I 0.949
irf4b Gasterosteus aculeatus ENSGACG00000004966 I 0.763
IRF8 Gorilla gorilla ENSGGOG00000028251 I 0.949
ENSLOCG00000001187 Lepisosteus oculatus ENSLOCG00000001187 I 0.768
ENSMICG00000011721 Microcebus murinus ENSMICG00000011721 I 0.804
IRF8 Macaca mulatta ENSMMUG00000008125 I 0.949
ENSMODG00000019483 Monodelphis domestica ENSMODG00000019483 I 0.729
ENSMPUG00000008641 Mustela putorius furo ENSMPUG00000008641 I 0.949
IRF8 Pan troglodytes ENSPTRG00000008435 I 0.949
IRF8 Ornithorhynchus anatinus ENSOANG00000003741 I 0.949
IRF4 Ornithorhynchus anatinus ENSOANG00000006326 I 0.754
IRF8 Otolemur garnettii ENSOGAG00000009262 I 0.949
irf4b Oryzias latipes ENSORLG00000012712 I 0.746
irf8 Oryzias latipes ENSORLG00000018216 I 0.915
ENSPANG00000023389 Papio anubis ENSPANG00000023389 I 0.807
ENSPANG00000024770 Papio anubis ENSPANG00000024770 I 0.949
ENSPFOG00000015506 Poecilia formosa ENSPFOG00000015506 I 0.763
ENSPPYG00000007620 Pongo abelii ENSPPYG00000007620 I 0.949
ENSAMXG00000016370 Astyanax mexicanus ENSAMXG00000016370 I 0.712
Alligator_sinensis_CCG000346.1 Alligator sinensis Alligator_sinensis_CCG000346.1 N 0.763