IRF5 (Homo sapiens)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSG00000128604 T244080_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF5
M03332_2.00		 Homo sapiens
YCGAAACCGAAMCY
RGKTTCGGTTTCGR		 SELEX
Jolma et al.(2013)
IRF5_1		 (Direct) (Direct)
IRF5
M03333_2.00		 Homo sapiens
HACCGAAACYV
BRGTTTCGGTD		 SELEX
Jolma et al.(2013)
IRF5_2		 (Direct) (Direct)
IRF5
M05535_2.00		 Homo sapiens
NCGAAACCGAWACH
DGTWTCGGTTTCGN		 SELEX
Yin et al.(2017)
IRF5_eDBD_HT-SELEX		 (Direct) (Direct)
IRF5
M05536_2.00		 Homo sapiens
NYGAWACYGAWACH
DGTWTCRGTWTCRN		 SELEX
Yin et al.(2017)
IRF5_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
IRF5
M05537_2.00		 Homo sapiens
NCGAAACCGAAACY
RGTTTCGGTTTCGN		 SELEX
Yin et al.(2017)
IRF5_FL_HT-SELEX		 (Direct) (Direct)
IRF5
M05538_2.00		 Homo sapiens
NYGAAACCGAWACY
RGTWTCGGTTTCRN		 SELEX
Yin et al.(2017)
IRF5_FL_Methyl-HT-SELEX		 (Direct) (Direct)
IRF5
M10884_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF5_Q3		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf5
M00177_2.00 		Mus musculus
NNNHGADASH
DSTHTCDNNN		 PBM
Badis et al.(2009)
Irf5_3874 		0.909 0.909
IRF5
M02256_2.00 		Oryctolagus cuniculus
NHCGAAACYN
NRGTTTCGDN		 PBM
Weirauch et al.(2014)
pTH9272 		0.900 0.900
irf5.L
M02260_2.00 		Xenopus laevis
VNCGADACHN
NDGTHTCGNB		 PBM
Weirauch et al.(2014)
pTH9367 		0.767 0.767
IRF6
M02253_2.00 		Gallus gallus
NNMCNAAWNN
NNWTTNGKNN		 PBM
Weirauch et al.(2014)
pTH9178 		0.724 0.724
IRF6
M02254_2.00 		Meleagris gallopavo
NRNCGAWACY
RGTWTCGNYN		 PBM
Weirauch et al.(2014)
pTH9210 		0.724 0.724
irf6.2
M02259_2.00 		Xenopus tropicalis
NVNHGAWACH
DGTWTCDNBN		 PBM
Weirauch et al.(2014)
pTH9302 		0.733 0.733
Irf6
M00176_2.00 		Mus musculus
NNNHGADASN
NSTHTCDNNN		 PBM
Badis et al.(2009)
Irf6_3803 		0.722 0.722
IRF6
M05527_2.00 		Homo sapiens
RGTWTCGNNNNNNYGAWACY
RGTWTCRNNNNNNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_HT-SELEX 		0.722 0.722
IRF6
M05529_2.00 		Homo sapiens
ACCGAAACT
AGTTTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_HT-SELEX 		0.722 0.722
IRF6
M05528_2.00 		Homo sapiens
RGTWTCGNHNNDNYGAWACY
RGTWTCRNHNNDNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_Methyl-HT-SELEX 		0.722 0.722
IRF6
M05530_2.00 		Homo sapiens
ACCGAWACY
RGTWTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_Methyl-HT-SELEX 		0.722 0.722
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000249375 IRF 16 121
ENSP00000349770 IRF 16 121
ENSP00000385352 IRF 16 121
ENSP00000417454 IRF 16 59
ENSP00000417770 IRF 16 121
ENSP00000418037 IRF 16 121
ENSP00000418534 IRF 16 120
ENSP00000419056 IRF 16 106
ENSP00000419149 IRF 16 121
ENSP00000419950 IRF 16 121
ENSP00000420274 IRF 16 79
ENSP00000480058 IRF 16 121
ENSP00000483292 IRF 16 120

Links

Other IRF family TFs
Other Homo sapiens TFs

121 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
NAC083 Arabidopsis thaliana AT5G13180 D
Bo2g011120 Brassica oleracea Bo2g011120 I
Bo3g009040 Brassica oleracea Bo3g009040 I
Bo4g181990 Brassica oleracea Bo4g181990 I
Bo9g168950 Brassica oleracea Bo9g168950 I
Bra006186 Brassica rapa Bra006186 I
Bra008849 Brassica rapa Bra008849 I
Bra021856 Brassica rapa Bra021856 I
Bra023395 Brassica rapa Bra023395 I
ANAC083 Arabidopsis lyrata scaffold_601328.1 I
Aquca_011_00050 Aquilegia coerulea Aquca_011_00050 I
Bostr.2902s0053 Boechera stricta Bostr.2902s0053 I
Cagra.0596s0010 Capsella grandiflora Cagra.0596s0010 I
Carubv10002548m.g Capsella rubella Carubv10002548m.g I
Thhalv10014495m.g Eutrema salsugineum Thhalv10014495m.g I
Cucsa.095210 Cucumis sativus Cucsa.095210 N