IRF6 (Gallus gallus)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSGALG00000001405 T244098_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF6
M02253_2.00		 Gallus gallus
NNMCNAAWNN
NNWTTNGKNN		 PBM
Weirauch et al.(2014)
pTH9178		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF6
M02254_2.00 		Meleagris gallopavo
NRNCGAWACY
RGTWTCGNYN		 PBM
Weirauch et al.(2014)
pTH9210 		0.990 0.990
irf6.2
M02259_2.00 		Xenopus tropicalis
NVNHGAWACH
DGTWTCDNBN		 PBM
Weirauch et al.(2014)
pTH9302 		0.962 0.962
Irf6
M00176_2.00 		Mus musculus
NNNHGADASN
NSTHTCDNNN		 PBM
Badis et al.(2009)
Irf6_3803 		0.933 0.933
IRF6
M05527_2.00 		Homo sapiens
RGTWTCGNNNNNNYGAWACY
RGTWTCRNNNNNNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_HT-SELEX 		0.933 0.933
IRF6
M05529_2.00 		Homo sapiens
ACCGAAACT
AGTTTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_HT-SELEX 		0.933 0.933
IRF6
M05528_2.00 		Homo sapiens
RGTWTCGNHNNDNYGAWACY
RGTWTCRNHNNDNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_Methyl-HT-SELEX 		0.933 0.933
IRF6
M05530_2.00 		Homo sapiens
ACCGAWACY
RGTWTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_Methyl-HT-SELEX 		0.933 0.933
irf5.L
M02260_2.00 		Xenopus laevis
VNCGADACHN
NDGTHTCGNB		 PBM
Weirauch et al.(2014)
pTH9367 		0.771 0.771
Irf5
M00177_2.00 		Mus musculus
NNNHGADASH
DSTHTCDNNN		 PBM
Badis et al.(2009)
Irf5_3874 		0.724 0.724
IRF5
M03332_2.00 		Homo sapiens
YCGAAACCGAAMCY
RGKTTCGGTTTCGR		 SELEX
Jolma et al.(2013)
IRF5_1 		0.724 0.724
IRF5
M03333_2.00 		Homo sapiens
HACCGAAACYV
BRGTTTCGGTD		 SELEX
Jolma et al.(2013)
IRF5_2 		0.724 0.724
IRF5
M05535_2.00 		Homo sapiens
NCGAAACCGAWACH
DGTWTCGGTTTCGN		 SELEX
Yin et al.(2017)
IRF5_eDBD_HT-SELEX 		0.724 0.724
IRF5
M05537_2.00 		Homo sapiens
NCGAAACCGAAACY
RGTTTCGGTTTCGN		 SELEX
Yin et al.(2017)
IRF5_FL_HT-SELEX 		0.724 0.724
IRF5
M10884_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF5_Q3 		0.724 0.724
IRF5
M05536_2.00 		Homo sapiens
NYGAWACYGAWACH
DGTWTCRGTWTCRN		 SELEX
Yin et al.(2017)
IRF5_eDBD_Methyl-HT-SELEX 		0.724 0.724
IRF5
M05538_2.00 		Homo sapiens
NYGAAACCGAWACY
RGTWTCGGTTTCRN		 SELEX
Yin et al.(2017)
IRF5_FL_Methyl-HT-SELEX 		0.724 0.724
IRF5
M02256_2.00 		Oryctolagus cuniculus
NHCGAAACYN
NRGTTTCGDN		 PBM
Weirauch et al.(2014)
pTH9272 		0.714 0.714
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02253_2.00 IRF 9 114

DNA Binding Domains

Protein ID Domain From To Sequence
ENSGALP00000039479 IRF 19 124

Links

Other IRF family TFs
Other Gallus gallus TFs

121 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAPLG00000009319 Anas platyrhynchos ENSAPLG00000009319 I 0.990
IRF6 Meleagris gallopavo ENSMGAG00000004431 D 0.990
IRF6 Taeniopygia guttata ENSTGUG00000001485 I 0.981
Afo_R001981 Aptenodytes forsteri Afo_R001981 I 0.981
Alligator_sinensis_CCG003696.1 Alligator sinensis Alligator_sinensis_CCG003696.1 I 0.971
IRF6 Ornithorhynchus anatinus ENSOANG00000013718 I 0.962
ENSPSIG00000003597 Pelodiscus sinensis ENSPSIG00000003597 I 0.962
Cmyd_10010684 Chelonia mydas Cmyd_10010684 I 0.962
irf6.2 Xenopus tropicalis XB-GENE-5910331 D 0.962
irf6.2.L Xenopus laevis XB-GENE-5910427 I 0.962
irf6.S Xenopus laevis XB-GENE-876421 I 0.962
IRF6 Anolis carolinensis ENSACAG00000005931 I 0.952
ENSMEUG00000014941 Macropus eugenii ENSMEUG00000014941 I 0.952
IRF6 Monodelphis domestica ENSMODG00000002539 I 0.952
Alligator_sinensis_CCG015719.1 Alligator sinensis Alligator_sinensis_CCG015719.1 I 0.952
irf6 Xenopus tropicalis XB-GENE-876410 I 0.952
ENSLACG00000018600 Latimeria chalumnae ENSLACG00000018600 I 0.943
IRF6 Sus scrofa ENSSSCG00000015612 I 0.940
ENSAMEG00000017984 Ailuropoda melanoleuca ENSAMEG00000017984 I 0.933
IRF6 Bos taurus ENSBTAG00000002849 I 0.933
IRF6 Canis familiaris ENSCAFG00000011971 I 0.933
IRF6 Choloepus hoffmanni ENSCHOG00000010399 I 0.933
IRF6 Callithrix jacchus ENSCJAG00000015032 I 0.933
IRF6 Cavia porcellus ENSCPOG00000023829 I 0.933
ENSCSAG00000015263 Chlorocebus sabaeus ENSCSAG00000015263 I 0.933
IRF6 Dasypus novemcinctus ENSDNOG00000001694 I 0.933
Irf6 Dipodomys ordii ENSDORG00000008891 I 0.933
IRF6 Equus caballus ENSECAG00000007482 I 0.933
IRF6 Echinops telfairi ENSETEG00000008368 I 0.933
IRF6 Felis catus ENSFCAG00000015138 I 0.933
IRF6 Homo sapiens ENSG00000117595 D 0.933
IRF6 Gorilla gorilla ENSGGOG00000006214 I 0.933
IRF6 Myotis lucifugus ENSMLUG00000004509 I 0.933
IRF6 Macaca mulatta ENSMMUG00000022065 I 0.933
ENSMPUG00000003106 Mustela putorius furo ENSMPUG00000003106 I 0.933
Irf6 Mus musculus ENSMUSG00000026638 D 0.933
ENSNLEG00000001962 Nomascus leucogenys ENSNLEG00000001962 I 0.933
ENSOARG00000012720 Ovis aries ENSOARG00000012720 I 0.933
IRF6 Oryctolagus cuniculus ENSOCUG00000004035 I 0.933
IRF6 Otolemur garnettii ENSOGAG00000010708 I 0.933
ENSPANG00000011328 Papio anubis ENSPANG00000011328 I 0.933
IRF6 Procavia capensis ENSPCAG00000006456 I 0.933
ENSPPYG00000000253 Pongo abelii ENSPPYG00000000253 I 0.933
IRF6 Pan troglodytes ENSPTRG00000001941 I 0.933
IRF6 Pteropus vampyrus ENSPVAG00000004865 I 0.933
Irf6 Rattus norvegicus ENSRNOG00000005082 I 0.933
ENSTSYG00000010982 Tarsius syrichta ENSTSYG00000010982 I 0.933
IRF6 Tursiops truncatus ENSTTRG00000001121 I 0.933
IRF6 Vicugna pacos ENSVPAG00000010247 I 0.933
ENSP00000349770-D2 Bos grunniens ENSP00000349770-D2 I 0.933
ENSP00000355988 Macaca fascicularis ENSP00000355988 I 0.933
Myotis_brandtii_IRF6_10012270 Myotis brandtii Myotis_brandtii_IRF6_10012270 I 0.933
Pvit_15428 Pogona vitticeps Pvit_15428 I 0.933
IRF6 Loxodonta africana ENSLAFG00000001374 I 0.924
ENSSTOG00000028204 Ictidomys tridecemlineatus ENSSTOG00000028204 I 0.924
ENSLOCG00000011297 Lepisosteus oculatus ENSLOCG00000011297 I 0.914
IRF6 Microcebus murinus ENSMICG00000001233 I 0.913
ENSOARG00000020948 Ovis aries ENSOARG00000020948 I 0.905
ENSAMXG00000004616 Astyanax mexicanus ENSAMXG00000004616 I 0.876
irf6 Danio rerio ENSDARG00000101986 I 0.876
ENSGMOG00000007988 Gadus morhua ENSGMOG00000007988 I 0.857
irf6 Oryzias latipes ENSORLG00000000511 I 0.857
irf6 Takifugu rubripes ENSTRUG00000006951 I 0.857
IRF6 Ochotona princeps ENSOPRG00000014295 I 0.848
irf6 Tetraodon nigroviridis ENSTNIG00000014635 I 0.848
irf6 Gasterosteus aculeatus ENSGACG00000000990 I 0.838
ENSONIG00000018961 Oreochromis niloticus ENSONIG00000018961 I 0.838
ENSPFOG00000014077 Poecilia formosa ENSPFOG00000014077 I 0.838
ENSPFOG00000005876 Poecilia formosa ENSPFOG00000005876 I 0.829
ENSXMAG00000007143 Xiphophorus maculatus ENSXMAG00000007143 I 0.829
Ogr12956 Ophisaurus gracilis Ogr12956 I 0.829
ENSPFOG00000013528 Poecilia formosa ENSPFOG00000013528 I 0.810
ENSXMAG00000013056 Xiphophorus maculatus ENSXMAG00000013056 I 0.810
ENSGMOG00000007264 Gadus morhua ENSGMOG00000007264 I 0.808
ENSONIG00000007600 Oreochromis niloticus ENSONIG00000007600 I 0.790
Alligator_sinensis_CCG004564.1 Alligator sinensis Alligator_sinensis_CCG004564.1 I 0.790
ENSLOCG00000015563 Lepisosteus oculatus ENSLOCG00000015563 I 0.781
irf5 Tetraodon nigroviridis ENSTNIG00000003346 I 0.781
irf5 Takifugu rubripes ENSTRUG00000000641 I 0.781
irf5 Danio rerio ENSDARG00000045681 I 0.771
irf5 Gasterosteus aculeatus ENSGACG00000000695 I 0.771
Pvit_14327 Pogona vitticeps Pvit_14327 I 0.771
irf5.L Xenopus laevis XB-GENE-998629 D 0.771
ENSLACG00000005750 Latimeria chalumnae ENSLACG00000005750 I 0.762
IRF5 Homo sapiens ENSG00000128604 D 0.756
Cmyd_10002838 Chelonia mydas Cmyd_10002838 I 0.752
irf5 Xenopus tropicalis XB-GENE-998624 I 0.752
ENSMEUG00000002435 Macropus eugenii ENSMEUG00000002435 I 0.743
IRF5 Monodelphis domestica ENSMODG00000014710 I 0.743
IRF5 Canis familiaris ENSCAFG00000001611 I 0.733
IRF5 Myotis lucifugus ENSMLUG00000001406 I 0.733
IRF5 Ornithorhynchus anatinus ENSOANG00000011449 I 0.733
Myotis_brandtii_IRF5_10012830 Myotis brandtii Myotis_brandtii_IRF5_10012830 I 0.733
ENSAMEG00000005109 Ailuropoda melanoleuca ENSAMEG00000005109 I 0.724
IRF5 Callithrix jacchus ENSCJAG00000018061 I 0.724
IRF5 Cavia porcellus ENSCPOG00000000246 I 0.724
ENSCSAG00000009970 Chlorocebus sabaeus ENSCSAG00000009970 I 0.724
IRF5 Dasypus novemcinctus ENSDNOG00000013370 I 0.724
Irf5 Dipodomys ordii ENSDORG00000010627 I 0.724
IRF5 Equus caballus ENSECAG00000009902 I 0.724
IRF5 Felis catus ENSFCAG00000000956 I 0.724
IRF5 Gorilla gorilla ENSGGOG00000012013 I 0.724
IRF5 Microcebus murinus ENSMICG00000000138 I 0.724
IRF5 Macaca mulatta ENSMMUG00000018478 I 0.724
ENSMPUG00000006034 Mustela putorius furo ENSMPUG00000006034 I 0.724
Irf5 Mus musculus ENSMUSG00000029771 D 0.724
ENSNLEG00000012454 Nomascus leucogenys ENSNLEG00000012454 I 0.724
ENSOARG00000003908 Ovis aries ENSOARG00000003908 I 0.724
IRF5 Ochotona princeps ENSOPRG00000006148 I 0.724
ENSPANG00000018384 Papio anubis ENSPANG00000018384 I 0.724
ENSPPYG00000017989 Pongo abelii ENSPPYG00000017989 I 0.724
IRF5 Pan troglodytes ENSPTRG00000019675 I 0.724
Irf5 Rattus norvegicus ENSRNOG00000007437 I 0.724
ENSSHAG00000006683 Sarcophilus harrisii ENSSHAG00000006683 I 0.724
IRF5 Sus scrofa ENSSSCG00000016573 I 0.724
ENSSTOG00000004858 Ictidomys tridecemlineatus ENSSTOG00000004858 I 0.724
ENSP00000349770-D1 Bos grunniens ENSP00000349770-D1 I 0.724
ENSP00000349770 Macaca fascicularis ENSP00000349770 I 0.724
IRF5 Bos taurus ENSBTAG00000004989 I 0.714
IRF5 Loxodonta africana ENSLAFG00000021568 I 0.714
IRF5 Oryctolagus cuniculus ENSOCUG00000010101 D 0.714