IRF6 (Meleagris gallopavo)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSMGAG00000004431 T244168_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF6
M02254_2.00		 Meleagris gallopavo
NRNCGAWACY
RGTWTCGNYN		 PBM
Weirauch et al.(2014)
pTH9210		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF6
M02253_2.00 		Gallus gallus
NNMCNAAWNN
NNWTTNGKNN		 PBM
Weirauch et al.(2014)
pTH9178 		0.990 0.990
irf6.2
M02259_2.00 		Xenopus tropicalis
NVNHGAWACH
DGTWTCDNBN		 PBM
Weirauch et al.(2014)
pTH9302 		0.971 0.971
Irf6
M00176_2.00 		Mus musculus
NNNHGADASN
NSTHTCDNNN		 PBM
Badis et al.(2009)
Irf6_3803 		0.943 0.943
IRF6
M05527_2.00 		Homo sapiens
RGTWTCGNNNNNNYGAWACY
RGTWTCRNNNNNNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_HT-SELEX 		0.943 0.943
IRF6
M05529_2.00 		Homo sapiens
ACCGAAACT
AGTTTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_HT-SELEX 		0.943 0.943
IRF6
M05528_2.00 		Homo sapiens
RGTWTCGNHNNDNYGAWACY
RGTWTCRNHNNDNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_Methyl-HT-SELEX 		0.943 0.943
IRF6
M05530_2.00 		Homo sapiens
ACCGAWACY
RGTWTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_Methyl-HT-SELEX 		0.943 0.943
irf5.L
M02260_2.00 		Xenopus laevis
VNCGADACHN
NDGTHTCGNB		 PBM
Weirauch et al.(2014)
pTH9367 		0.781 0.781
Irf5
M00177_2.00 		Mus musculus
NNNHGADASH
DSTHTCDNNN		 PBM
Badis et al.(2009)
Irf5_3874 		0.724 0.724
IRF5
M03332_2.00 		Homo sapiens
YCGAAACCGAAMCY
RGKTTCGGTTTCGR		 SELEX
Jolma et al.(2013)
IRF5_1 		0.724 0.724
IRF5
M03333_2.00 		Homo sapiens
HACCGAAACYV
BRGTTTCGGTD		 SELEX
Jolma et al.(2013)
IRF5_2 		0.724 0.724
IRF5
M05535_2.00 		Homo sapiens
NCGAAACCGAWACH
DGTWTCGGTTTCGN		 SELEX
Yin et al.(2017)
IRF5_eDBD_HT-SELEX 		0.724 0.724
IRF5
M05537_2.00 		Homo sapiens
NCGAAACCGAAACY
RGTTTCGGTTTCGN		 SELEX
Yin et al.(2017)
IRF5_FL_HT-SELEX 		0.724 0.724
IRF5
M10884_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF5_Q3 		0.724 0.724
IRF5
M05536_2.00 		Homo sapiens
NYGAWACYGAWACH
DGTWTCRGTWTCRN		 SELEX
Yin et al.(2017)
IRF5_eDBD_Methyl-HT-SELEX 		0.724 0.724
IRF5
M05538_2.00 		Homo sapiens
NYGAAACCGAWACY
RGTWTCGGTTTCRN		 SELEX
Yin et al.(2017)
IRF5_FL_Methyl-HT-SELEX 		0.724 0.724
IRF5
M02256_2.00 		Oryctolagus cuniculus
NHCGAAACYN
NRGTTTCGDN		 PBM
Weirauch et al.(2014)
pTH9272 		0.714 0.714
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02254_2.00 IRF 9 114

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMGAP00000004262 IRF 9 114

Links

Other IRF family TFs
Other Meleagris gallopavo TFs

121 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAPLG00000009319 Anas platyrhynchos ENSAPLG00000009319 I 1.000
IRF6 Gallus gallus ENSGALG00000001405 D 0.990
IRF6 Taeniopygia guttata ENSTGUG00000001485 I 0.990
Afo_R001981 Aptenodytes forsteri Afo_R001981 I 0.990
Alligator_sinensis_CCG003696.1 Alligator sinensis Alligator_sinensis_CCG003696.1 I 0.981
IRF6 Ornithorhynchus anatinus ENSOANG00000013718 I 0.971
ENSPSIG00000003597 Pelodiscus sinensis ENSPSIG00000003597 I 0.971
Cmyd_10010684 Chelonia mydas Cmyd_10010684 I 0.971
irf6.2 Xenopus tropicalis XB-GENE-5910331 D 0.971
irf6.2.L Xenopus laevis XB-GENE-5910427 I 0.971
irf6.S Xenopus laevis XB-GENE-876421 I 0.971
IRF6 Anolis carolinensis ENSACAG00000005931 I 0.962
ENSMEUG00000014941 Macropus eugenii ENSMEUG00000014941 I 0.962
IRF6 Monodelphis domestica ENSMODG00000002539 I 0.962
Alligator_sinensis_CCG015719.1 Alligator sinensis Alligator_sinensis_CCG015719.1 I 0.962
irf6 Xenopus tropicalis XB-GENE-876410 I 0.962
ENSLACG00000018600 Latimeria chalumnae ENSLACG00000018600 I 0.952
ENSAMEG00000017984 Ailuropoda melanoleuca ENSAMEG00000017984 I 0.943
IRF6 Bos taurus ENSBTAG00000002849 I 0.943
IRF6 Canis familiaris ENSCAFG00000011971 I 0.943
IRF6 Choloepus hoffmanni ENSCHOG00000010399 I 0.943
IRF6 Callithrix jacchus ENSCJAG00000015032 I 0.943
IRF6 Cavia porcellus ENSCPOG00000023829 I 0.943
ENSCSAG00000015263 Chlorocebus sabaeus ENSCSAG00000015263 I 0.943
IRF6 Dasypus novemcinctus ENSDNOG00000001694 I 0.943
Irf6 Dipodomys ordii ENSDORG00000008891 I 0.943
IRF6 Equus caballus ENSECAG00000007482 I 0.943
IRF6 Echinops telfairi ENSETEG00000008368 I 0.943
IRF6 Felis catus ENSFCAG00000015138 I 0.943
IRF6 Homo sapiens ENSG00000117595 D 0.943
IRF6 Gorilla gorilla ENSGGOG00000006214 I 0.943
IRF6 Myotis lucifugus ENSMLUG00000004509 I 0.943
IRF6 Macaca mulatta ENSMMUG00000022065 I 0.943
ENSMPUG00000003106 Mustela putorius furo ENSMPUG00000003106 I 0.943
Irf6 Mus musculus ENSMUSG00000026638 D 0.943
ENSNLEG00000001962 Nomascus leucogenys ENSNLEG00000001962 I 0.943
ENSOARG00000012720 Ovis aries ENSOARG00000012720 I 0.943
IRF6 Oryctolagus cuniculus ENSOCUG00000004035 I 0.943
IRF6 Otolemur garnettii ENSOGAG00000010708 I 0.943
ENSPANG00000011328 Papio anubis ENSPANG00000011328 I 0.943
IRF6 Procavia capensis ENSPCAG00000006456 I 0.943
ENSPPYG00000000253 Pongo abelii ENSPPYG00000000253 I 0.943
IRF6 Pan troglodytes ENSPTRG00000001941 I 0.943
IRF6 Pteropus vampyrus ENSPVAG00000004865 I 0.943
Irf6 Rattus norvegicus ENSRNOG00000005082 I 0.943
IRF6 Sus scrofa ENSSSCG00000015612 I 0.943
ENSTSYG00000010982 Tarsius syrichta ENSTSYG00000010982 I 0.943
IRF6 Tursiops truncatus ENSTTRG00000001121 I 0.943
IRF6 Vicugna pacos ENSVPAG00000010247 I 0.943
ENSP00000349770-D2 Bos grunniens ENSP00000349770-D2 I 0.943
ENSP00000355988 Macaca fascicularis ENSP00000355988 I 0.943
Myotis_brandtii_IRF6_10012270 Myotis brandtii Myotis_brandtii_IRF6_10012270 I 0.943
Pvit_15428 Pogona vitticeps Pvit_15428 I 0.943
IRF6 Loxodonta africana ENSLAFG00000001374 I 0.933
ENSSTOG00000028204 Ictidomys tridecemlineatus ENSSTOG00000028204 I 0.933
ENSLOCG00000011297 Lepisosteus oculatus ENSLOCG00000011297 I 0.924
IRF6 Microcebus murinus ENSMICG00000001233 I 0.923
ENSOARG00000020948 Ovis aries ENSOARG00000020948 I 0.914
ENSAMXG00000004616 Astyanax mexicanus ENSAMXG00000004616 I 0.886
irf6 Danio rerio ENSDARG00000101986 I 0.886
ENSGMOG00000007988 Gadus morhua ENSGMOG00000007988 I 0.867
irf6 Oryzias latipes ENSORLG00000000511 I 0.867
irf6 Takifugu rubripes ENSTRUG00000006951 I 0.867
IRF6 Ochotona princeps ENSOPRG00000014295 I 0.857
irf6 Tetraodon nigroviridis ENSTNIG00000014635 I 0.857
irf6 Gasterosteus aculeatus ENSGACG00000000990 I 0.848
ENSONIG00000018961 Oreochromis niloticus ENSONIG00000018961 I 0.848
ENSPFOG00000005876 Poecilia formosa ENSPFOG00000005876 I 0.838
ENSXMAG00000007143 Xiphophorus maculatus ENSXMAG00000007143 I 0.838
Ogr12956 Ophisaurus gracilis Ogr12956 I 0.838
ENSPFOG00000014077 Poecilia formosa ENSPFOG00000014077 I 0.829
ENSPFOG00000013528 Poecilia formosa ENSPFOG00000013528 I 0.819
ENSXMAG00000013056 Xiphophorus maculatus ENSXMAG00000013056 I 0.819
ENSGMOG00000007264 Gadus morhua ENSGMOG00000007264 I 0.810
ENSONIG00000007600 Oreochromis niloticus ENSONIG00000007600 I 0.800
Alligator_sinensis_CCG004564.1 Alligator sinensis Alligator_sinensis_CCG004564.1 I 0.800
ENSLOCG00000015563 Lepisosteus oculatus ENSLOCG00000015563 I 0.790
irf5 Tetraodon nigroviridis ENSTNIG00000003346 I 0.790
irf5 Takifugu rubripes ENSTRUG00000000641 I 0.790
irf5 Danio rerio ENSDARG00000045681 I 0.781
irf5 Gasterosteus aculeatus ENSGACG00000000695 I 0.781
Pvit_14327 Pogona vitticeps Pvit_14327 I 0.781
irf5.L Xenopus laevis XB-GENE-998629 D 0.781
ENSLACG00000005750 Latimeria chalumnae ENSLACG00000005750 I 0.771
Cmyd_10002838 Chelonia mydas Cmyd_10002838 I 0.762
irf5 Xenopus tropicalis XB-GENE-998624 I 0.762
IRF5 Homo sapiens ENSG00000128604 D 0.756
ENSMEUG00000002435 Macropus eugenii ENSMEUG00000002435 I 0.743
IRF5 Monodelphis domestica ENSMODG00000014710 I 0.743
IRF5 Canis familiaris ENSCAFG00000001611 I 0.733
IRF5 Myotis lucifugus ENSMLUG00000001406 I 0.733
IRF5 Ornithorhynchus anatinus ENSOANG00000011449 I 0.733
Myotis_brandtii_IRF5_10012830 Myotis brandtii Myotis_brandtii_IRF5_10012830 I 0.733
ENSAMEG00000005109 Ailuropoda melanoleuca ENSAMEG00000005109 I 0.724
IRF5 Callithrix jacchus ENSCJAG00000018061 I 0.724
IRF5 Cavia porcellus ENSCPOG00000000246 I 0.724
ENSCSAG00000009970 Chlorocebus sabaeus ENSCSAG00000009970 I 0.724
IRF5 Dasypus novemcinctus ENSDNOG00000013370 I 0.724
Irf5 Dipodomys ordii ENSDORG00000010627 I 0.724
IRF5 Equus caballus ENSECAG00000009902 I 0.724
IRF5 Felis catus ENSFCAG00000000956 I 0.724
IRF5 Gorilla gorilla ENSGGOG00000012013 I 0.724
IRF5 Microcebus murinus ENSMICG00000000138 I 0.724
IRF5 Macaca mulatta ENSMMUG00000018478 I 0.724
ENSMPUG00000006034 Mustela putorius furo ENSMPUG00000006034 I 0.724
Irf5 Mus musculus ENSMUSG00000029771 D 0.724
ENSNLEG00000012454 Nomascus leucogenys ENSNLEG00000012454 I 0.724
ENSOARG00000003908 Ovis aries ENSOARG00000003908 I 0.724
IRF5 Ochotona princeps ENSOPRG00000006148 I 0.724
ENSPANG00000018384 Papio anubis ENSPANG00000018384 I 0.724
ENSPPYG00000017989 Pongo abelii ENSPPYG00000017989 I 0.724
IRF5 Pan troglodytes ENSPTRG00000019675 I 0.724
Irf5 Rattus norvegicus ENSRNOG00000007437 I 0.724
ENSSHAG00000006683 Sarcophilus harrisii ENSSHAG00000006683 I 0.724
IRF5 Sus scrofa ENSSSCG00000016573 I 0.724
ENSSTOG00000004858 Ictidomys tridecemlineatus ENSSTOG00000004858 I 0.724
ENSP00000349770-D1 Bos grunniens ENSP00000349770-D1 I 0.724
ENSP00000349770 Macaca fascicularis ENSP00000349770 I 0.724
IRF5 Bos taurus ENSBTAG00000004989 I 0.714
IRF5 Loxodonta africana ENSLAFG00000021568 I 0.714
IRF5 Oryctolagus cuniculus ENSOCUG00000010101 D 0.714