KLF12 (Choloepus hoffmanni)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSCHOG00000003950 T088800_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Klf12
M00787_2.00 		Mus musculus
NNHMCRCCCH
DGGGYGKDNN		 PBM
Weirauch et al.(2013)
pTH0977 		0.827 1.000
Klf12
M02937_2.00 		Mus musculus
GRCCACGCCCWHHHN
NDDDWGGGCGTGGYC		 SELEX
Jolma et al.(2013)
Klf12_1 		0.827 1.000
KLF12
M04430_2.00 		Homo sapiens
DRCCACGCCCH
DGGGCGTGGYH		 SELEX
Yin et al.(2017)
KLF12_FL_HT-SELEX 		0.827 1.000
KLF12
M08299_2.00 		Homo sapiens
SBNVGCCMCGCCCHB
VDGGGCGKGGCBNVS		 ChIP-seq
Schmitges et al.(2016)
Q9Y4X4.MEME 		0.827 1.000
KLF12
M08879_2.00 		Homo sapiens
GCCCCGCCCYB
VRGGGCGGGGC		 Misc
Kulakovskiy et al.(2013)
KLF12_HUMAN.H11MO.0.C 		0.827 1.000
KLF12
M10186_2.00 		Homo sapiens
HMYACDG
CHGTRKD		 Transfac
Matys et al.(2006)
V$AP2REP_01 		0.827 1.000
KLF12
M04431_2.00 		Homo sapiens
RGSCGACGCCCN
NGGGCGTCGSCY		 SELEX
Yin et al.(2017)
KLF12_FL_Methyl-HT-SELEX_1 		0.827 1.000
KLF12
M04432_2.00 		Homo sapiens
NRCCACGCCCH
DGGGCGTGGYN		 SELEX
Yin et al.(2017)
KLF12_FL_Methyl-HT-SELEX_2 		0.827 1.000
Klf7
M00134_2.00 		Mus musculus
NHHMCRCCCH
DGGGYGKDDN		 PBM
Badis et al.(2009)
Klf7_0974 		0.806 0.841
KLF7
M08298_2.00 		Homo sapiens
VVCHMCGCCCH
DGGGCGKDGBB		 ChIP-seq
Schmitges et al.(2016)
O75840.MEME 		0.806 0.841
KLF3
M04418_2.00 		Homo sapiens
RRCCRCGCCCH
DGGGCGYGGYY		 SELEX
Yin et al.(2017)
KLF3_FL_HT-SELEX 		0.801 0.942
KLF3
M08876_2.00 		Homo sapiens
NSNNVCCMCRCCCHBBBBN
NVVVVDGGGYGKGGBNNSN		 Misc
Kulakovskiy et al.(2013)
KLF3_HUMAN.H11MO.0.B 		0.801 0.942
Klf3
M08982_2.00 		Mus musculus
NSNNVCCMCRCCCHBBBBN
NVVVVDGGGYGKGGBNNSN		 Misc
Kulakovskiy et al.(2013)
KLF3_MOUSE.H11MO.0.A 		0.801 0.942
KLF3
M10172_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF3_Q3_01 		0.801 0.942
KLF3
M10173_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF3_Q3 		0.801 0.942
KLF3
M04419_2.00 		Homo sapiens
DRCCACGCCCH
DGGGCGTGGYH		 SELEX
Yin et al.(2017)
KLF3_FL_Methyl-HT-SELEX_1 		0.801 0.942
KLF3
M04420_2.00 		Homo sapiens
RRSCGCARCCCN
NGGGYTGCGSYY		 SELEX
Yin et al.(2017)
KLF3_FL_Methyl-HT-SELEX_2 		0.801 0.942
luna
M03704_2.00 		Drosophila melanogaster
RCCACRCCCH
DGGGYGTGGY		 SELEX
Nitta et al.(2015)
luna_1 		0.790 0.826
luna
M06163_2.00 		Drosophila melanogaster
RRMHMCRCCC
GGGYGKDKYY		 B1H
Zhu et al.(2011)
luna_SANGER_5_FBgn0040765 		0.790 0.826
luna
M06164_2.00 		Drosophila melanogaster
DRCCMCGCCCHNNN
NNNDGGGCGKGGYH		 B1H
Zhu et al.(2011)
luna_SOLEXA_5_FBgn0040765 		0.790 0.826
KLF6
M04400_2.00 		Homo sapiens
NVMCACRCCCH
DGGGYGTGKBN		 SELEX
Yin et al.(2017)
KLF6_eDBD_HT-SELEX 		0.790 0.812
KLF6
M08857_2.00 		Homo sapiens
BYBYVNBCYMCDCCCYBBN
NVVRGGGHGKRGVNBRVRV		 Misc
Kulakovskiy et al.(2013)
KLF6_HUMAN.H11MO.0.A 		0.790 0.812
Klf6
M08962_2.00 		Mus musculus
BYBYVNBCYMCDCCCYBBN
NVVRGGGHGKRGVNBRVRV		 Misc
Kulakovskiy et al.(2013)
KLF6_MOUSE.H11MO.0.B 		0.790 0.812
KLF6
M10113_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CPBP_Q6 		0.790 0.812
KLF6
M04401_2.00 		Homo sapiens
NRCCACGCCCH
DGGGCGTGGYN		 SELEX
Yin et al.(2017)
KLF6_eDBD_Methyl-HT-SELEX 		0.790 0.812
KLF5
M04410_2.00 		Homo sapiens
NMCACRCCCH
DGGGYGTGKN		 SELEX
Yin et al.(2017)
KLF5_eDBD_HT-SELEX 		0.781 0.841
KLF5
M08086_2.00 		Homo sapiens
BCCMCDCCCH
DGGGHGKGGV		 ChIP-seq
Mathelier et al.(2014)
MA0599.1 		0.781 0.841
KLF5
M08868_2.00 		Homo sapiens
NHVNRCCMCDCCCH
DGGGHGKGGYNBDN		 Misc
Kulakovskiy et al.(2013)
KLF5_HUMAN.H11MO.0.A 		0.781 0.841
Klf5
M08965_2.00 		Mus musculus
KCCMCDCCCHBBBCH
DGVVVDGGGHGKGGM		 Misc
Kulakovskiy et al.(2013)
KLF5_MOUSE.H11MO.0.A 		0.781 0.841
KLF5
M09502_2.00 		Homo sapiens
GCCMCRCCCH
DGGGYGKGGC		 Misc
Heinz et al.(2010)
LoVo-KLF5_GSE49402 		0.781 0.841
KLF5
M10149_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BTEB2_Q3_01 		0.781 0.841
KLF5
M10150_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BTEB2_Q3 		0.781 0.841
KLF5
M04411_2.00 		Homo sapiens
NMCACRCCYH
DRGGYGTGKN		 SELEX
Yin et al.(2017)
KLF5_eDBD_Methyl-HT-SELEX 		0.781 0.841
Klf8
M00779_2.00 		Mus musculus
NNNMCRCCYN
NRGGYGKNNN		 PBM
Weirauch et al.(2013)
pTH3086 		0.772 0.870
KLF8
M08867_2.00 		Homo sapiens
CACMCMCKG
CMGKGKGTG		 Misc
Kulakovskiy et al.(2013)
KLF8_HUMAN.H11MO.0.C 		0.772 0.870
Klf8
M09000_2.00 		Mus musculus
CACMCMCKG
CMGKGKGTG		 Misc
Kulakovskiy et al.(2013)
KLF8_MOUSE.H11MO.0.C 		0.772 0.870
KLF8
M10147_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF8_Q5_01 		0.772 0.870
KLF8
M10148_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF8_Q5 		0.772 0.870
dar1
M06171_2.00 		Drosophila melanogaster
RMCACACCCWH
DWGGGTGTGKY		 B1H
Zhu et al.(2011)
CG12029_SANGER_10_FBgn0035454 		0.767 0.783
dar1
M06172_2.00 		Drosophila melanogaster
NNNRCCACRCCCHNN
NNDGGGYGTGGYNNN		 B1H
Zhu et al.(2011)
CG12029_SOLEXA_5_FBgn0035454 		0.767 0.783
KLF4
M04463_2.00 		Homo sapiens
NVCCACRCCCH
DGGGYGTGGBN		 SELEX
Yin et al.(2017)
KLF4_eDBD_HT-SELEX 		0.762 0.812
KLF4
M08091_2.00 		Homo sapiens
MCACACCCWNN
NNWGGGTGTGK		 ChIP-seq
Mathelier et al.(2014)
MA0039.3 		0.762 0.812
Klf4
M08021_2.00 		Mus musculus
VRCCMCRCCCH
DGGGYGKGGYB		 ChIP-seq
Chen et al.(2011)
SRP000217_Klf4 		0.762 0.812
KLF4
M08243_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 ChIP-seq
Najafabadi et al.(2015b)
KLF14 		0.762 0.812
KLF4
M08894_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 Misc
Kulakovskiy et al.(2013)
KLF4_HUMAN.H11MO.0.A 		0.762 0.812
Klf4
M08964_2.00 		Mus musculus
GCCMCRCCCWBYBBN
NVVRVWGGGYGKGGC		 Misc
Kulakovskiy et al.(2013)
KLF4_MOUSE.H11MO.0.A 		0.762 0.812
KLF4
M10217_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_02 		0.762 0.812
KLF4
M10218_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q3_01 		0.762 0.812
KLF4
M10219_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q3 		0.762 0.812
KLF4
M10220_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q4 		0.762 0.812
KLF4
M04464_2.00 		Homo sapiens
NVCCMCRCCCN
NGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF4_eDBD_Methyl-HT-SELEX 		0.762 0.812
KLF1
M00226_2.00 		Homo sapiens
CMCGCCCM
KGGGCGKG		 PBM
Barrera et al.(2016)
KLF1_REF 		0.762 0.783
KLF1
M08293_2.00 		Homo sapiens
NVNNNRCCMCRCCCH
DGGGYGKGGYNNNBN		 ChIP-seq
Schmitges et al.(2016)
Q13351.MEME 		0.762 0.783
KLF1
M08871_2.00 		Homo sapiens
SVNDGCCMCRCCCH
DGGGYGKGGCHNBS		 Misc
Kulakovskiy et al.(2013)
KLF1_HUMAN.H11MO.0.A 		0.762 0.783
KLF1
M10163_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EKLF_Q5_01 		0.762 0.783
KLF1
M10164_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EKLF_Q5 		0.762 0.783
KLF1
M00224_2.00 		Homo sapiens
YMCGCCCH
DGGGCGKR		 PBM
Barrera et al.(2016)
KLF1_H299Y 		0.762 0.768
CG42741
M06169_2.00 		Drosophila melanogaster
RCCACRCCCWHY
RDWGGGYGTGGY		 B1H
Zhu et al.(2011)
CG9895_SANGER_10_FBgn0034810 		0.759 0.826
CG42741
M06170_2.00 		Drosophila melanogaster
VRCCACRCCCH
DGGGYGTGGYB		 B1H
Zhu et al.(2011)
CG9895_SOLEXA_5_FBgn0034810 		0.759 0.826
KLF2
M04455_2.00 		Homo sapiens
NVCCMCRCCCH
DGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF2_eDBD_HT-SELEX 		0.758 0.797
KLF2
M10210_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LKLF_Q3 		0.758 0.797
KLF2
M10211_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LKLF_Q6 		0.758 0.797
KLF2
M04456_2.00 		Homo sapiens
NVCCMCRCCCN
NGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF2_eDBD_Methyl-HT-SELEX 		0.758 0.797
Klf1
M08099_2.00 		Mus musculus
NRCCACACCCW
WGGGTGTGGYN		 ChIP-seq
Mathelier et al.(2014)
MA0493.1 		0.758 0.768
Klf1
M09008_2.00 		Mus musculus
MVMNSCCMCRCCCH
DGGGYGKGGSNKBK		 Misc
Kulakovskiy et al.(2013)
KLF1_MOUSE.H11MO.0.A 		0.758 0.768
Klf1
M09516_2.00 		Mus musculus
DRCCACACCCWN
NWGGGTGTGGYH		 Misc
Heinz et al.(2010)
Erythrocyte-Klf1_GSE20478 		0.758 0.768
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCHOP00000003495 C2H2 ZF 308 332
ENSCHOP00000003495 C2H2 ZF 338 362
ENSCHOP00000003495 C2H2 ZF 368 390

Links

Other C2H2 ZF family TFs
Other Choloepus hoffmanni TFs

735 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
29589.m001269 Ricinus communis 29589.m001269 N
AMTR_s00140p00061590 Amborella trichopoda AMTR_s00140p00061590 N
Aquca_009_01096 Aquilegia coerulea Aquca_009_01096 N
BGIOSGA015622 Oryza indica BGIOSGA015622 N
BGIOSGA026480 Oryza indica BGIOSGA026480 N
BRADI3G12490 Brachypodium distachyon BRADI3G12490 N
cassava27114.m1 Manihot esculenta cassava27114.m1 N
cassava28521.m1 Manihot esculenta cassava28521.m1 N
Ca_07000 Cicer arietinum Ca_07000 N
chr3.CM0070.360.nc Lotus japonicus chr3.CM0070.360.nc N
Ciclev10029807m.g Citrus clementina Ciclev10029807m.g N
Ciclev10029984m.g Citrus clementina Ciclev10029984m.g N
Cla001892 Citrullus lanatus Cla001892 N
Cucsa.200410 Cucumis sativus Cucsa.200410 N
Eucgr.B03926 Eucalyptus grandis Eucgr.B03926 N
Eucgr.J00391 Eucalyptus grandis Eucgr.J00391 N
gene01102-v1.0-hybrid Fragaria vesca gene01102-v1.0-hybrid N
GLYMA11G19810 Glycine max GLYMA11G19810 N
GLYMA12G08680 Glycine max GLYMA12G08680 N
GLYMA12G30285 Glycine max GLYMA12G30285 N
GLYMA13G39610 Glycine max GLYMA13G39610 N
Gorai.006G104700 Gossypium raimondii Gorai.006G104700 N
GSMUA_Achr11G02230_001 Musa acuminata GSMUA_Achr11G02230_001 N
GSMUA_Achr1G15330_001 Musa acuminata GSMUA_Achr1G15330_001 N
LPERR08G20460 Leersia perrieri LPERR08G20460 N
MDP0000224892 Malus domestica MDP0000224892 N
MDP0000610922 Malus domestica MDP0000610922 N
mgf025993m Mimulus guttatus mgf025993m N
OB08G30610 Oryza brachyantha OB08G30610 N
OBART04G02230 Oryza barthii OBART04G02230 N
OGLUM04G01880 Oryza glumaepatula OGLUM04G01880 N
OGLUM08G25260 Oryza glumaepatula OGLUM08G25260 N
OLONG_023180 Oryza longistaminata OLONG_023180 N
OMERI04G02190 Oryza meridionalis OMERI04G02190 N
OMERI08G18590 Oryza meridionalis OMERI08G18590 N
ONIVA08G18580 Oryza nivara ONIVA08G18580 N
OPUNC04G02200 Oryza punctata OPUNC04G02200 N
OPUNC08G21710 Oryza punctata OPUNC08G21710 N
orange1.1g042026m.g Citrus sinensis orange1.1g042026m.g N
orange1.1g044007m.g Citrus sinensis orange1.1g044007m.g N
ORGLA04G0016600 Oryza glaberrima ORGLA04G0016600 N
ORGLA08G0191700 Oryza glaberrima ORGLA08G0191700 N
ORUFI04G02970 Oryza rufipogon ORUFI04G02970 N
ORUFI08G26260 Oryza rufipogon ORUFI08G26260 N
OS04G0165200 Oryza sativa OS04G0165200 N
OS08G0562300 Oryza sativa OS08G0562300 N
Pavir.Fa00049 Panicum virgatum Pavir.Fa00049 N
Pavir.Fb02219 Panicum virgatum Pavir.Fb02219 N
PGSC0003DMG400000419 Solanum tuberosum PGSC0003DMG400000419 N
Pm001162 Prunus mume Pm001162 N
POPTR_0004s22670 Populus trichocarpa POPTR_0004s22670 N
PRUPE_ppa019036mg Prunus persica PRUPE_ppa019036mg N
SapurV1A.0360s0140 Salix purpurea SapurV1A.0360s0140 N
Sb07g023890 Sorghum bicolor Sb07g023890 N
Si013894m.g Setaria italica Si013894m.g N
Solyc11g066420.1 Solanum lycopersicum Solyc11g066420.1 N
TCM_041585 Theobroma cacao TCM_041585 N
TRIUR3_12142 Triticum urartu TRIUR3_12142 N
VIT_06s0061g00780 Vitis vinifera VIT_06s0061g00780 N