CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

Pax5B *(Gallus gallus)* Paired box
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00292 (PAX)	IPR001523	ENSGALG00000016431	T311654_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Pax5B M01301_2.00	Gallus gallus	NSNDTNNNN	NNNNAHNSN	PBM Lambert et al.(2019) pTH9781	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
PAX5 M03443_2.00	Homo sapiens	RNBYANYSAWSCGTRACN	NGTYACGSWTSRNTRVNY	SELEX Jolma et al.(2013) PAX5_1	1.000	1.000
PAX5 M08160_2.00	Homo sapiens	RDGCGTGACCNN	NNGGTCACGCHY	ChIP-seq Mathelier et al.(2014) MA0014.3	1.000	1.000
PAX5 M07995_2.00	Homo sapiens	BCAVYSRDSCRKRRC	GYYMYGSHYSRBTGV	ChIP-seq Gerstein et al.(2012) GM12878_PAX5C20_HudsonAlpha	1.000	1.000
PAX5 M07996_2.00	Homo sapiens	BCASYSRDSCRTRAC	GTYAYGSHYSRSTGV	ChIP-seq Gerstein et al.(2012) GM12878_PAX5N19_HudsonAlpha	1.000	1.000
PAX5 M07997_2.00	Homo sapiens	CASYSRDSCRKRACN	NGTYMYGSHYSRSTG	ChIP-seq Gerstein et al.(2012) GM12891_PAX5C20_HudsonAlpha	1.000	1.000
PAX5 M07998_2.00	Homo sapiens	BCASYSRDSCGKRRC	GYYMCGSHYSRSTGV	ChIP-seq Gerstein et al.(2012) GM12892_PAX5C20_HudsonAlpha	1.000	1.000
PAX5 M08227_2.00	Homo sapiens	BCANYSRDGCGTRAM	KTYACGCHYSRNTGV	ChIP-seq Contrino et al.(2012) Mv108	1.000	1.000
PAX5 M08228_2.00	Homo sapiens	AGCGTGRCYG	CRGYCACGCT	ChIP-seq Contrino et al.(2012) Mv109	1.000	1.000
PAX5 M09341_2.00	Homo sapiens	SNVDGNKCARCVRAGCRDGAC	GTCHYGCTYBGYTGMNCHBNS	Misc Kulakovskiy et al.(2013) PAX5_HUMAN.H11MO.0.A	1.000	1.000
Pax5 M09342_2.00	Mus musculus	VDRNBCAVYVRDSCRKRRM	KYYMYGSHYBRBTGVNYHB	Misc Kulakovskiy et al.(2013) PAX5_MOUSE.H11MO.0.A	1.000	1.000
PAX5 M09622_2.00	Homo sapiens	BCASYSRDSCRTGRMN	NKYCAYGSHYSRSTGV	Misc Heinz et al.(2010) GM12878-PAX5_GSE32465_1	1.000	1.000
PAX5 M09623_2.00	Homo sapiens	BCABNVRSCGTGAC	GTCACGSYBNVTGV	Misc Heinz et al.(2010) GM12878-PAX5_GSE32465_2	1.000	1.000
PAX5 M11208_2.00	Homo sapiens	BCNNNRNKCANBGNWGNRKRGMSRSHNB	VNDSYSKCYMYNCWNCVNTGMNYNNNGV	Transfac Matys et al.(2006) V$PAX5_01	1.000	1.000
PAX5 M11209_2.00	Homo sapiens	VRHVDGDNDBBTNRAGCGKRACVRYNVH	DBNRYBGTYMCGCTYNAVVHNHCHBDYB	Transfac Matys et al.(2006) V$PAX5_02	1.000	1.000
PAX5 M11210_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_06	1.000	1.000
PAX5 M11211_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_07	1.000	1.000
PAX5 M11212_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_Q6	1.000	1.000
pax2 M02428_2.00	Xenopus tropicalis	NNNRNBCRNN	NNYGVNYNNN	PBM Weirauch et al.(2014) pTH8556	0.976	0.976
pax2b M02425_2.00	Danio rerio	HVNYSRNSCR	YGSNYSRNBD	PBM Weirauch et al.(2014) pTH8679	0.968	0.968
PAX8 M05685_2.00	Homo sapiens	NRNBYRNYSRWGCGTGACSN	NSGTCACGCWYSRNYRVNYN	SELEX Yin et al.(2017) PAX8_FL_HT-SELEX	0.936	0.936
Pax8 M09624_2.00	Rattus norvegicus	BCAGBCADSCRKGVM	KBCMYGSHTGVCTGV	Misc Heinz et al.(2010) Thyroid-Pax8_GSE26938	0.936	0.936
PAX8 M11205_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX8_01	0.936	0.936
PAX8 M11206_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX8_B	0.936	0.936
PAX8 M05686_2.00	Homo sapiens	NRNBCRNTSAWSCGYGACNN	NNGTCRCGSWTSANYGVNYN	SELEX Yin et al.(2017) PAX8_FL_Methyl-HT-SELEX	0.936	0.936
sv M01302_2.00	Drosophila melanogaster	NNNSCRBRDM	KHYVYGSNNN	PBM Lambert et al.(2019) pTH9773	0.880	0.880
sv M03949_2.00	Drosophila melanogaster	NBCRNYSAWGCGTGACS	SGTCACGCWTSRNYGVN	SELEX Nitta et al.(2015) sv_1	0.880	0.880
sv M06438_2.00	Drosophila melanogaster	RNYSRDSCGTRACNN	NNGTYACGSHYSRNY	B1H Zhu et al.(2011) sv_SOLEXA_5_FBgn0005561	0.880	0.880
egl-38 M02426_2.00	Caenorhabditis elegans	ACCGTGAYCAC	GTGRTCACGGT	PBM Weirauch et al.(2014) pTH8981	0.752	0.752
pax-2 M00706_2.00	Caenorhabditis elegans	RMSCRTRACS	SGTYAYGSKY	PBM Narasimhan et al.(2015) pTH10794	0.752	0.752
Poxn M03946_2.00	Drosophila melanogaster	DGCGTGACSGTCACGSY	RSCGTGACSGTCACGCH	SELEX Nitta et al.(2015) Poxn_1	0.744	0.744
Poxn M03947_2.00	Drosophila melanogaster	RSCGKGACSGTTMCGSW	WSCGKAACSGTCMCGSY	SELEX Nitta et al.(2015) Poxn_2	0.744	0.744
Poxn M03948_2.00	Drosophila melanogaster	NCGTTCCGGAACGD	HCGTTCCGGAACGN	SELEX Nitta et al.(2015) Poxn_3	0.744	0.744
Poxn M06437_2.00	Drosophila melanogaster	RSCGTGACG	CGTCACGSY	B1H Zhu et al.(2011) Poxn_SOLEXA_5_FBgn0003130	0.744	0.744
PAX7 M00346_2.00	Homo sapiens	NGTYAYGSHN	NDSCRTRACN	PBM Barrera et al.(2016) PAX7_REF	0.736	0.736
PAX1 M03442_2.00	Homo sapiens	DBCANTSAWGCGTGACS	SGTCACGCWTSANTGVH	SELEX Jolma et al.(2013) PAX1_1	0.736	0.736
PAX9 M03444_2.00	Homo sapiens	NKCANTSAWGCGTGACS	SGTCACGCWTSANTGMN	SELEX Jolma et al.(2013) PAX9_1	0.736	0.736
Poxm M03944_2.00	Drosophila melanogaster	CAVTCAWGCGTGACR	YGTCACGCWTGABTG	SELEX Nitta et al.(2015) Poxm_1	0.736	0.736
Poxm M03945_2.00	Drosophila melanogaster	NYSAWGCRTRACS	SGTYAYGCWTSRN	SELEX Nitta et al.(2015) Poxm_2	0.736	0.736
PAX1 M05687_2.00	Homo sapiens	BCRNTSRWGCGTGACSN	NSGTCACGCWYSANYGV	SELEX Yin et al.(2017) PAX1_eDBD_HT-SELEX	0.736	0.736
PAX9 M05689_2.00	Homo sapiens	BHRNYSRDSCGTRACSN	NSGTYACGSHYSRNYDV	SELEX Yin et al.(2017) PAX9_eDBD_HT-SELEX	0.736	0.736
Poxm M06436_2.00	Drosophila melanogaster	NNNNNNMVNHNRNSCRTGA	TCAYGSNYNDNBKNNNNNN	B1H Zhu et al.(2011) Poxm_SOLEXA_5_FBgn0003129	0.736	0.736
PAX1 M11207_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX1_B	0.736	0.736
PAX1 M05688_2.00	Homo sapiens	BCRNTSAWGCGTGACSN	NSGTCACGCWTSANYGV	SELEX Yin et al.(2017) PAX1_eDBD_Methyl-HT-SELEX	0.736	0.736
PAX9 M05690_2.00	Homo sapiens	BCRNTSAWSCGYGACNN	NNGTCRCGSWTSANYGV	SELEX Yin et al.(2017) PAX9_eDBD_Methyl-HT-SELEX	0.736	0.736
pax9 M11204_2.00	Danio rerio	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX9_B	0.728	0.728
PAX7 M00345_2.00	Homo sapiens	NSGTCACGSN	NSCGTGACSN	PBM Barrera et al.(2016) PAX7_P112L	0.728	0.728
For this family, TFs with SR scores > 0.700* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M01301_2.00	Paired box	1	125	GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIR

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSGALP00000026458	Paired box	16	140	GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIR

Links
Other Paired box family TFs
Other *Gallus gallus* TFs

608 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
ENSCSAG00000003729	Chlorocebus sabaeus	ENSCSAG00000003729	I	0.000
ENSECAG00000011516	Equus caballus	ENSECAG00000011516	N	0.000
ENSMPUG00000017415	Mustela putorius furo	ENSMPUG00000017415	N	0.000
ENSNLEG00000009107	Nomascus leucogenys	ENSNLEG00000009107	I	0.000
ENSP00000264808	Macaca fascicularis	ENSP00000264808	N	0.000
ENSPANG00000023612	Papio anubis	ENSPANG00000023612	N	0.000
ENSPPYG00000015031	Pongo abelii	ENSPPYG00000015031	N	0.000
PRDM5	Dasypus novemcinctus	ENSDNOG00000002009	N	0.000
PRDM5	Loxodonta africana	ENSLAFG00000006532	I	0.000
PRDM5	Macaca mulatta	ENSMMUG00000003249	N	0.000
PRDM5	Callithrix jacchus	ENSCJAG00000003133	I	0.000
Prdm5	Mus musculus	ENSMUSG00000029913	D	0.000
PRDM5	Canis familiaris	ENSCAFG00000004179	N	0.000
PRDM5	Pteropus vampyrus	ENSPVAG00000012309	I	0.000
PRDM5	Sus scrofa	ENSSSCG00000009101	N	0.000
PRDM5	Tursiops truncatus	ENSTTRG00000010996	N	0.000
PRDM5	Bos taurus	ENSBTAG00000012111	N	0.000

Pax5B (Gallus gallus) Paired box

TF Information

Directly determined binding motifs

Motifs from related TFs

Experimental Constructs

DNA Binding Domains

Links

608 Related TFs

Pax5B **(Gallus gallus)
Paired box**