MITF (Dasypus novemcinctus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSDNOG00000037006 T033811_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Mitf
M01741_2.00 		Mus musculus
NCDCGTGAYN
NRTCACGHGN		 PBM
Weirauch et al.(2014)
pTH5465 		0.914 1.000
MITF
M08058_2.00 		Homo sapiens
NNNDRTCACGTGAYHNNN
NNNDRTCACGTGAYHNNN		 ChIP-seq
Mathelier et al.(2014)
MA0620.2 		0.914 1.000
MITF
M08740_2.00 		Homo sapiens
YCAYGTGACH
DGTCACRTGR		 Misc
Kulakovskiy et al.(2013)
MITF_HUMAN.H11MO.0.A 		0.914 1.000
Mitf
M08765_2.00 		Mus musculus
BCHYGTGACY
RGTCACRDGV		 Misc
Kulakovskiy et al.(2013)
MITF_MOUSE.H11MO.0.A 		0.914 1.000
Mitf
M09475_2.00 		Mus musculus
GTCACRWGVB
VBCWYGTGAC		 Misc
Heinz et al.(2010)
MastCells-MITF_GSE48085 		0.914 1.000
MITF
M09880_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MITF_Q4 		0.914 1.000
MITF
M09881_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MITF_Q6 		0.914 1.000
Tfe3
M01715_2.00 		Mus musculus
NCDCRTGAYN
NRTCAYGHGN		 PBM
Weirauch et al.(2014)
pTH5057 		0.914 0.981
Tfe3
M05833_2.00 		Mus musculus
CACGTGAY
RTCACGTG		 SMiLE-seq
Isakova et al.(2017)
TFE3 		0.914 0.981
Tfe3
M08743_2.00 		Mus musculus
TCACGTGACH
DGTCACGTGA		 Misc
Kulakovskiy et al.(2013)
TFE3_MOUSE.H11MO.0.A 		0.914 0.981
Tfe3
M09884_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFEA_01 		0.914 0.981
TFE3
M02773_2.00 		Homo sapiens
VNCACGTGMY
RKCACGTGNB		 SELEX
Jolma et al.(2013)
TFE3_1 		0.871 0.963
TFE3
M04058_2.00 		Homo sapiens
YVCACGTGAYN
NRTCACGTGBR		 SELEX
Yin et al.(2017)
TFE3_eDBD_HT-SELEX 		0.871 0.963
TFE3
M08709_2.00 		Homo sapiens
TCACGTGACH
DGTCACGTGA		 Misc
Kulakovskiy et al.(2013)
TFE3_HUMAN.H11MO.0.B 		0.871 0.963
TFE3
M09790_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFEA_Q6 		0.871 0.963
TFE3
M04059_2.00 		Homo sapiens
NRTCACATGBB
VVCATGTGAYN		 SELEX
Yin et al.(2017)
TFE3_eDBD_Methyl-HT-SELEX 		0.871 0.963
Tfec
M00755_2.00 		Mus musculus
NNCACGTGNN
NNCACGTGNN		 PBM
Weirauch et al.(2013)
pTH2885 		0.870 0.926
Tfec
M01736_2.00 		Mus musculus
NCNCRTGVYN
NRBCAYGNGN		 PBM
Weirauch et al.(2014)
pTH5065 		0.870 0.926
TFEC
M02778_2.00 		Homo sapiens
RNCACRTGAB
VTCAYGTGNY		 SELEX
Jolma et al.(2013)
TFEC_1 		0.870 0.907
TFEC
M04078_2.00 		Homo sapiens
NVCACGTGACN
NGTCACGTGBN		 SELEX
Yin et al.(2017)
TFEC_eDBD_HT-SELEX 		0.870 0.907
TFEC
M04079_2.00 		Homo sapiens
VNCATGTGAYN
NRTCACATGNB		 SELEX
Yin et al.(2017)
TFEC_eDBD_Methyl-HT-SELEX 		0.870 0.907
Tfeb
M01728_2.00 		Mus musculus
CWCGTGAY
RTCACGWG		 PBM
Weirauch et al.(2014)
pTH5072 		0.855 0.889
TFEB
M02781_2.00 		Homo sapiens
RNCACGTGAY
RTCACGTGNY		 SELEX
Jolma et al.(2013)
TFEB_1 		0.855 0.889
TFEB
M02727_2.00 		Homo sapiens
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2010)
TFEB_dimer 		0.855 0.889
TFEB
M04088_2.00 		Homo sapiens
YVCACGTGAYN
NRTCACGTGBR		 SELEX
Yin et al.(2017)
TFEB_eDBD_HT-SELEX 		0.855 0.889
TFEB
M08718_2.00 		Homo sapiens
CACGTGAYY
RRTCACGTG		 Misc
Kulakovskiy et al.(2013)
TFEB_HUMAN.H11MO.0.C 		0.855 0.889
Tfeb
M08753_2.00 		Mus musculus
CACGTGAYY
RRTCACGTG		 Misc
Kulakovskiy et al.(2013)
TFEB_MOUSE.H11MO.0.C 		0.855 0.889
TFEB
M04089_2.00 		Homo sapiens
VNCATGTGAYN
NRTCACATGNB		 SELEX
Yin et al.(2017)
TFEB_eDBD_Methyl-HT-SELEX 		0.855 0.889
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDNOP00000027369 bHLH 296 349

Links

Other bHLH family TFs
Other Dasypus novemcinctus TFs

242 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000000518 Ailuropoda melanoleuca ENSAMEG00000000518 I 0.000
ENSAMEG00000002719 Ailuropoda melanoleuca ENSAMEG00000002719 I 0.000
ENSAMEG00000011648 Ailuropoda melanoleuca ENSAMEG00000011648 I 0.000
Alligator_sinensis_CCG008980.1 Alligator sinensis Alligator_sinensis_CCG008980.1 I 0.000
Alligator_sinensis_CCG015583.1 Alligator sinensis Alligator_sinensis_CCG015583.1 I 0.000
ENSAPLG00000010507 Anas platyrhynchos ENSAPLG00000010507 I 0.000
ENSAPLG00000012713 Anas platyrhynchos ENSAPLG00000012713 I 0.000
ENSAPLG00000015149 Anas platyrhynchos ENSAPLG00000015149 I 0.000
HIVEP3 Anolis carolinensis ENSACAG00000000262 I 0.000
HIVEP1 Anolis carolinensis ENSACAG00000008494 I 0.000
Afo_R010148 Aptenodytes forsteri Afo_R010148 N 0.000
Afo_R013233 Aptenodytes forsteri Afo_R013233 I 0.000
Afo_R014870 Aptenodytes forsteri Afo_R014870 I 0.000
ENSAMXG00000000689 Astyanax mexicanus ENSAMXG00000000689 I 0.000
ENSAMXG00000010476 Astyanax mexicanus ENSAMXG00000010476 I 0.000
ENSAMXG00000017196 Astyanax mexicanus ENSAMXG00000017196 I 0.000
ENSAMXG00000020146 Astyanax mexicanus ENSAMXG00000020146 I 0.000
BGIBMGA003672 Bombyx mori BGIBMGA003672 I 0.000
ENSBTAP00000001526-D1 Bos grunniens ENSBTAP00000001526-D1 I 0.000
ENSP00000247584-D1 Bos grunniens ENSP00000247584-D1 I 0.000
ENSP00000368698-D1 Bos grunniens ENSP00000368698-D1 I 0.000
HIVEP2 Bos taurus ENSBTAG00000001146 I 0.000
HIVEP1 Bos taurus ENSBTAG00000001252 I 0.000
HIVEP3 Bos taurus ENSBTAG00000020745 I 0.000
BTMF_0001307101 Brugia timori BTMF_0001307101 N 0.000
Brh_R013004 Buceros rhinoceros Brh_R013004 I 0.000
Brh_R013551 Buceros rhinoceros Brh_R013551 I 0.000
HIVEP1 Callithrix jacchus ENSCJAG00000005100 I 0.000
HIVEP2 Callithrix jacchus ENSCJAG00000019190 I 0.000
Aan_R001556 Calypte anna Aan_R001556 I 0.000
Aan_R009469 Calypte anna Aan_R009469 N 0.000
Aan_R009807 Calypte anna Aan_R009807 I 0.000
HIVEP2 Canis familiaris ENSCAFG00000000300 I 0.000
HIVEP3 Canis familiaris ENSCAFG00000002576 I 0.000
HIVEP1 Canis familiaris ENSCAFG00000009791 I 0.000
HIVEP2 Cavia porcellus ENSCPOG00000005191 I 0.000
HIVEP1 Cavia porcellus ENSCPOG00000007524 I 0.000
ENSCPOG00000014328 Cavia porcellus ENSCPOG00000014328 I 0.000
Cmyd_10012369 Chelonia mydas Cmyd_10012369 I 0.000
Cmyd_10012979 Chelonia mydas Cmyd_10012979 I 0.000
ENSCSAG00000001159 Chlorocebus sabaeus ENSCSAG00000001159 I 0.000
ENSCSAG00000007502 Chlorocebus sabaeus ENSCSAG00000007502 I 0.000
ENSCSAG00000017065 Chlorocebus sabaeus ENSCSAG00000017065 I 0.000
ENSCHOG00000013422 Choloepus hoffmanni ENSCHOG00000013422 N 0.000
hivep2b Danio rerio ENSDARG00000018773 I 0.000
hivep2a Danio rerio ENSDARG00000039987 I 0.000
hivep3a Danio rerio ENSDARG00000075928 I 0.000
hivep1 Danio rerio ENSDARG00000103658 I 0.000
HIVEP1 Dasypus novemcinctus ENSDNOG00000036467 I 0.000
HIVEP3 Dasypus novemcinctus ENSDNOG00000043199 I 0.000
HIVEP2 Dasypus novemcinctus ENSDNOG00000049597 I 0.000
YQE_08862 Dendroctonus ponderosae YQE_08862 N 0.000
Hivep2 Dipodomys ordii ENSDORG00000004767 I 0.000
Hivep1 Dipodomys ordii ENSDORG00000012154 I 0.000
HIVEP1 Echinops telfairi ENSETEG00000015103 I 0.000
HIVEP2 Equus caballus ENSECAG00000009836 I 0.000
HIVEP1 Equus caballus ENSECAG00000010759 I 0.000
HIVEP3 Equus caballus ENSECAG00000018490 I 0.000
HIVEP1 Erinaceus europaeus ENSEEUG00000008935 I 0.000
HIVEP2 Erinaceus europaeus ENSEEUG00000013365 I 0.000
HIVEP1 Felis catus ENSFCAG00000002227 I 0.000
HIVEP3 Felis catus ENSFCAG00000014035 I 0.000
HIVEP2 Felis catus ENSFCAG00000030851 I 0.000
ENSFALG00000001148 Ficedula albicollis ENSFALG00000001148 I 0.000
ENSFALG00000012744 Ficedula albicollis ENSFALG00000012744 I 0.000
ENSFALG00000013366 Ficedula albicollis ENSFALG00000013366 N 0.000
ENSGMOG00000003043 Gadus morhua ENSGMOG00000003043 I 0.000
ENSGMOG00000011398 Gadus morhua ENSGMOG00000011398 I 0.000
ENSGMOG00000012811 Gadus morhua ENSGMOG00000012811 I 0.000
HIVEP1 Gallus gallus ENSGALG00000012739 I 0.000
HIVEP2 Gallus gallus ENSGALG00000013795 I 0.000
HIVEP3 Gallus gallus ENSGALG00000027365 I 0.000
hivep1 Gasterosteus aculeatus ENSGACG00000002352 I 0.000
hivep2b Gasterosteus aculeatus ENSGACG00000011743 I 0.000
hivep2a Gasterosteus aculeatus ENSGACG00000011974 I 0.000
Gfo_R000665 Geospiza fortis Gfo_R000665 I 0.000
Gfo_R003803 Geospiza fortis Gfo_R003803 I 0.000
HIVEP1 Gorilla gorilla ENSGGOG00000016169 I 0.000
HIVEP2 Gorilla gorilla ENSGGOG00000016466 I 0.000
HIVEP3 Gorilla gorilla ENSGGOG00000016974 I 0.000
HIVEP2 Homo sapiens ENSG00000010818 D 0.000
HIVEP1 Homo sapiens ENSG00000095951 I 0.000
HIVEP3 Homo sapiens ENSG00000127124 I 0.000
ENSSTOG00000025109 Ictidomys tridecemlineatus ENSSTOG00000025109 I 0.000
ENSSTOG00000025365 Ictidomys tridecemlineatus ENSSTOG00000025365 N 0.000
ENSSTOG00000028355 Ictidomys tridecemlineatus ENSSTOG00000028355 I 0.000
ENSLACG00000006616 Latimeria chalumnae ENSLACG00000006616 I 0.000
ENSLACG00000016032 Latimeria chalumnae ENSLACG00000016032 I 0.000
ENSLACG00000016748 Latimeria chalumnae ENSLACG00000016748 I 0.000
ENSLOCG00000000567 Lepisosteus oculatus ENSLOCG00000000567 I 0.000
ENSLOCG00000003625 Lepisosteus oculatus ENSLOCG00000003625 I 0.000
ENSLOCG00000007963 Lepisosteus oculatus ENSLOCG00000007963 I 0.000
LotgiG60668 Lottia gigantea LotgiG60668 N 0.000
HIVEP2 Loxodonta africana ENSLAFG00000009644 I 0.000
ENSLAFG00000011036 Loxodonta africana ENSLAFG00000011036 N 0.000
HIVEP3 Loxodonta africana ENSLAFG00000017582 I 0.000
ENSP00000012134 Macaca fascicularis ENSP00000012134 I 0.000
ENSP00000361664 Macaca fascicularis ENSP00000361664 I 0.000
ENSP00000368698 Macaca fascicularis ENSP00000368698 I 0.000
HIVEP2 Macaca mulatta ENSMMUG00000007998 I 0.000
HIVEP3 Macaca mulatta ENSMMUG00000016215 I 0.000
ENSMEUG00000003500 Macropus eugenii ENSMEUG00000003500 I 0.000
ENSMEUG00000011068 Macropus eugenii ENSMEUG00000011068 N 0.000
ENSMEUG00000014160 Macropus eugenii ENSMEUG00000014160 I 0.000
MESCA003516 Megaselia scalaris MESCA003516 N 0.000
HIVEP3 Meleagris gallopavo ENSMGAG00000000881 I 0.000
HIVEP1 Meleagris gallopavo ENSMGAG00000003391 I 0.000
HIVEP2 Meleagris gallopavo ENSMGAG00000012956 I 0.000
Minc02686 Meloidogyne incognita Minc02686 N 0.000
ENSMICG00000010424 Microcebus murinus ENSMICG00000010424 I 0.000
ENSMICG00000016732 Microcebus murinus ENSMICG00000016732 I 0.000
HIVEP1 Monodelphis domestica ENSMODG00000010547 I 0.000
HIVEP2 Monodelphis domestica ENSMODG00000017268 I 0.000
HIVEP3 Monodelphis domestica ENSMODG00000017330 I 0.000
ENSMPUG00000000674 Mustela putorius furo ENSMPUG00000000674 I 0.000
ENSMPUG00000014066 Mustela putorius furo ENSMPUG00000014066 I 0.000
ENSMPUG00000018042 Mustela putorius furo ENSMPUG00000018042 I 0.000
Hivep2 Mus musculus ENSMUSG00000015501 I 0.000
Hivep1 Mus musculus ENSMUSG00000021366 I 0.000
Hivep3 Mus musculus ENSMUSG00000028634 I 0.000
Myotis_brandtii_HIVEP1_10025408 Myotis brandtii Myotis_brandtii_HIVEP1_10025408 I 0.000
Myotis_brandtii_HIVEP2_10035753 Myotis brandtii Myotis_brandtii_HIVEP2_10035753 I 0.000
Myotis_brandtii_HIVEP3_10016763 Myotis brandtii Myotis_brandtii_HIVEP3_10016763 I 0.000
HIVEP2 Myotis lucifugus ENSMLUG00000001764 I 0.000
HIVEP3 Myotis lucifugus ENSMLUG00000004675 I 0.000
HIVEP1 Myotis lucifugus ENSMLUG00000016059 I 0.000
ENSNLEG00000000728 Nomascus leucogenys ENSNLEG00000000728 I 0.000
ENSNLEG00000012279 Nomascus leucogenys ENSNLEG00000012279 I 0.000
ENSNLEG00000015066 Nomascus leucogenys ENSNLEG00000015066 I 0.000
HIVEP1 Ochotona princeps ENSOPRG00000008394 I 0.000
HIVEP2 Ochotona princeps ENSOPRG00000015623 I 0.000
Ogr06337 Ophisaurus gracilis Ogr06337 I 0.000
Ogr11119 Ophisaurus gracilis Ogr11119 I 0.000
Ogr15910 Ophisaurus gracilis Ogr15910 N 0.000
ENSONIG00000000567 Oreochromis niloticus ENSONIG00000000567 I 0.000
ENSONIG00000006743 Oreochromis niloticus ENSONIG00000006743 I 0.000
ENSONIG00000013692 Oreochromis niloticus ENSONIG00000013692 I 0.000
ENSONIG00000018691 Oreochromis niloticus ENSONIG00000018691 I 0.000
HIVEP1 Ornithorhynchus anatinus ENSOANG00000007196 I 0.000
HIVEP2 Ornithorhynchus anatinus ENSOANG00000007666 I 0.000
HIVEP3 Oryctolagus cuniculus ENSOCUG00000001203 I 0.000
HIVEP2 Oryctolagus cuniculus ENSOCUG00000005139 I 0.000
HIVEP1 Oryctolagus cuniculus ENSOCUG00000012379 I 0.000
hivep2b Oryzias latipes ENSORLG00000008843 I 0.000
hivep1 Oryzias latipes ENSORLG00000009270 I 0.000
hivep2a Oryzias latipes ENSORLG00000018133 I 0.000
HIVEP1 Otolemur garnettii ENSOGAG00000012509 I 0.000
HIVEP2 Otolemur garnettii ENSOGAG00000017073 I 0.000
HIVEP3 Otolemur garnettii ENSOGAG00000028118 I 0.000
ENSOARG00000001505 Ovis aries ENSOARG00000001505 I 0.000
ENSOARG00000014356 Ovis aries ENSOARG00000014356 I 0.000
ENSOARG00000020378 Ovis aries ENSOARG00000020378 I 0.000
HIVEP3 Pan troglodytes ENSPTRG00000000603 I 0.000
HIVEP1 Pan troglodytes ENSPTRG00000017729 I 0.000
HIVEP2 Pan troglodytes ENSPTRG00000018665 I 0.000
ENSPANG00000000913 Papio anubis ENSPANG00000000913 I 0.000
ENSPANG00000010311 Papio anubis ENSPANG00000010311 I 0.000
ENSPANG00000026003 Papio anubis ENSPANG00000026003 I 0.000
ENSPSIG00000004550 Pelodiscus sinensis ENSPSIG00000004550 I 0.000
ENSPSIG00000009360 Pelodiscus sinensis ENSPSIG00000009360 I 0.000
ENSPSIG00000016202 Pelodiscus sinensis ENSPSIG00000016202 I 0.000
ENSPMAG00000003790 Petromyzon marinus ENSPMAG00000003790 I 0.000
ENSPFOG00000005423 Poecilia formosa ENSPFOG00000005423 I 0.000
ENSPFOG00000009215 Poecilia formosa ENSPFOG00000009215 I 0.000
ENSPFOG00000016130 Poecilia formosa ENSPFOG00000016130 I 0.000
ENSPFOG00000016971 Poecilia formosa ENSPFOG00000016971 I 0.000
Pvit_07058 Pogona vitticeps Pvit_07058 I 0.000
Pvit_17261 Pogona vitticeps Pvit_17261 I 0.000
Pvit_18524 Pogona vitticeps Pvit_18524 I 0.000
ENSPPYG00000001475 Pongo abelii ENSPPYG00000001475 I 0.000
ENSPPYG00000016236 Pongo abelii ENSPPYG00000016236 I 0.000
ENSPPYG00000017057 Pongo abelii ENSPPYG00000017057 I 0.000
HIVEP2 Procavia capensis ENSPCAG00000007184 I 0.000
HIVEP3 Pteropus vampyrus ENSPVAG00000006103 I 0.000
HIVEP2 Pteropus vampyrus ENSPVAG00000012091 I 0.000
HIVEP1 Pteropus vampyrus ENSPVAG00000014003 I 0.000
Hivep3 Rattus norvegicus ENSRNOG00000009341 I 0.000
Hivep2 Rattus norvegicus ENSRNOG00000011015 I 0.000
Hivep1 Rattus norvegicus ENSRNOG00000014460 N 0.000
ENSSHAG00000006346 Sarcophilus harrisii ENSSHAG00000006346 I 0.000
ENSSHAG00000008159 Sarcophilus harrisii ENSSHAG00000008159 I 0.000
ENSSHAG00000015534 Sarcophilus harrisii ENSSHAG00000015534 I 0.000
SBAD_0001041801 Soboliphyme baturini SBAD_0001041801 N 0.000
HIVEP1 Sorex araneus ENSSARG00000006713 I 0.000
HIVEP1 Sus scrofa ENSSSCG00000001049 I 0.000
HIVEP2 Sus scrofa ENSSSCG00000004138 I 0.000
ENSTGUG00000005813 Taeniopygia guttata ENSTGUG00000005813 I 0.000
HIVEP2 Taeniopygia guttata ENSTGUG00000010974 I 0.000
hivep2b Takifugu rubripes ENSTRUG00000007039 I 0.000
hivep1 Takifugu rubripes ENSTRUG00000010871 I 0.000
hivep3b Takifugu rubripes ENSTRUG00000013983 I 0.000
hivep2a Takifugu rubripes ENSTRUG00000015889 I 0.000
ENSTSYG00000001970 Tarsius syrichta ENSTSYG00000001970 I 0.000
ENSTSYG00000014008 Tarsius syrichta ENSTSYG00000014008 I 0.000
hivep1 Tetraodon nigroviridis ENSTNIG00000004491 I 0.000
hivep3b Tetraodon nigroviridis ENSTNIG00000009667 I 0.000
hivep2a Tetraodon nigroviridis ENSTNIG00000010718 I 0.000
hivep2b Tetraodon nigroviridis ENSTNIG00000019322 I 0.000
HIVEP2 Tupaia belangeri ENSTBEG00000016088 N 0.000
HIVEP3 Tursiops truncatus ENSTTRG00000005582 I 0.000
HIVEP2 Tursiops truncatus ENSTTRG00000015014 I 0.000
HIVEP1 Tursiops truncatus ENSTTRG00000016828 I 0.000
Tal_R003271 Tyto alba Tal_R003271 I 0.000
Tal_R004673 Tyto alba Tal_R004673 I 0.000
ENSVPAG00000003809 Vicugna pacos ENSVPAG00000003809 I 0.000
hivep3.L Xenopus laevis XB-GENE-864883 N 0.000
hivep1.S Xenopus laevis XB-GENE-865233 I 0.000
hivep2.L Xenopus laevis XB-GENE-865555 N 0.000
hivep1 Xenopus tropicalis XB-GENE-479002 I 0.000
hivep3 Xenopus tropicalis XB-GENE-482557 I 0.000
hivep2 Xenopus tropicalis XB-GENE-485854 I 0.000
ENSXMAG00000010646 Xiphophorus maculatus ENSXMAG00000010646 I 0.000
ENSXMAG00000013507 Xiphophorus maculatus ENSXMAG00000013507 I 0.000
ENSXMAG00000015035 Xiphophorus maculatus ENSXMAG00000015035 I 0.000
ENSXMAG00000016142 Xiphophorus maculatus ENSXMAG00000016142 I 0.000