MSC (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000178860 T034325_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MSC
M02801_2.00		 Homo sapiens
AACAGCTGTT
AACAGCTGTT		 SELEX
Jolma et al.(2013)
MSC_1		 (Direct) (Direct)
MSC
M04183_2.00		 Homo sapiens
NRMCAGMTGBYN
NRVCAKCTGKYN		 SELEX
Yin et al.(2017)
MSC_eDBD_HT-SELEX_1		 (Direct) (Direct)
MSC
M04184_2.00		 Homo sapiens
NRVCAYVTGBYN
NRVCABRTGBYN		 SELEX
Yin et al.(2017)
MSC_eDBD_HT-SELEX_2		 (Direct) (Direct)
MSC
M04185_2.00		 Homo sapiens
NRVCAGCTGBBN
NVVCAGCTGBYN		 SELEX
Yin et al.(2017)
MSC_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
MSC
M04186_2.00		 Homo sapiens
BRMCATATGKYV
BRMCATATGKYV		 SELEX
Yin et al.(2017)
MSC_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)
MSC
M04187_2.00		 Homo sapiens
NRMCAGCTGBYV
BRVCAGCTGKYN		 SELEX
Yin et al.(2017)
MSC_FL_HT-SELEX_1		 (Direct) (Direct)
MSC
M04188_2.00		 Homo sapiens
BRMCATATGKYN
NRMCATATGKYV		 SELEX
Yin et al.(2017)
MSC_FL_HT-SELEX_2		 (Direct) (Direct)
MSC
M04189_2.00		 Homo sapiens
BRACAGCTGTYV
BRACAGCTGTYV		 SELEX
Yin et al.(2017)
MSC_FL_Methyl-HT-SELEX_1		 (Direct) (Direct)
MSC
M04190_2.00		 Homo sapiens
BRMCATATGKYV
BRMCATATGKYV		 SELEX
Yin et al.(2017)
MSC_FL_Methyl-HT-SELEX_2		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Msc
M01730_2.00 		Mus musculus
NVCRKMYGBN
NVCRKMYGBN		 PBM
Weirauch et al.(2014)
pTH5112 		0.914 1.000
Tcf21
M01746_2.00 		Mus musculus
RMCAKMTGK
MCAKMTGKY		 PBM
Weirauch et al.(2014)
pTH5087 		0.914 0.981
Tcf21
M02819_2.00 		Mus musculus
VNAACAGCTGTTVN
NBAACAGCTGTTNB		 SELEX
Jolma et al.(2013)
Tcf21_1 		0.914 0.981
TCF21
M04092_2.00 		Homo sapiens
BAACAGCTGBYN
NRVCAGCTGTTV		 SELEX
Yin et al.(2017)
TCF21_eDBD_HT-SELEX_1 		0.914 0.981
TCF21
M04093_2.00 		Homo sapiens
NRCCATATGKYV
BRMCATATGGYN		 SELEX
Yin et al.(2017)
TCF21_eDBD_HT-SELEX_2 		0.914 0.981
TCF21
M04094_2.00 		Homo sapiens
BAACAGCTGTYV
BRACAGCTGTTV		 SELEX
Yin et al.(2017)
TCF21_eDBD_Methyl-HT-SELEX_1 		0.914 0.981
TCF21
M04095_2.00 		Homo sapiens
BACCATATGKYV
BRMCATATGGTV		 SELEX
Yin et al.(2017)
TCF21_eDBD_Methyl-HT-SELEX_2 		0.914 0.981
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000321445 bHLH 108 160

Links

Other bHLH family TFs
Other Homo sapiens TFs

188 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
F775_12743 Aegilops tauschii F775_12743 N
BRADI2G49250 Brachypodium distachyon BRADI2G49250 N
Bo7g117320 Brassica oleracea Bo7g117320 I
Cagra.2350s0072 Capsella grandiflora Cagra.2350s0072 I
evm.TU.supercontig_249.7 Carica papaya evm.TU.supercontig_249.7 I
Ca_05641 Cicer arietinum Ca_05641 I
Eucgr.F02262 Eucalyptus grandis Eucgr.F02262 I
GLYMA10G40400 Glycine max GLYMA10G40400 I
MLOC_51405 Hordeum vulgare MLOC_51405 I
LPERR03G19190 Leersia perrieri LPERR03G19190 N
LPERR03G21480 Leersia perrieri LPERR03G21480 I
GSMUA_Achr7G20260_001 Musa acuminata GSMUA_Achr7G20260_001 N
GSMUA_Achr6G34890_001 Musa acuminata GSMUA_Achr6G34890_001 I
GSMUA_Achr10G31400_001 Musa acuminata GSMUA_Achr10G31400_001 N
OBART03G22560 Oryza barthii OBART03G22560 N
OBART03G22570 Oryza barthii OBART03G22570 I
OB03G31780 Oryza brachyantha OB03G31780 I
OB03G31790 Oryza brachyantha OB03G31790 N
ORGLA03G0210300 Oryza glaberrima ORGLA03G0210300 I
ORGLA03G0210200 Oryza glaberrima ORGLA03G0210200 N
OGLUM03G23340 Oryza glumaepatula OGLUM03G23340 N
OGLUM03G23350 Oryza glumaepatula OGLUM03G23350 I
BGIOSGA010468 Oryza indica BGIOSGA010468 I
BGIOSGA010470 Oryza indica BGIOSGA010470 N
BGIOSGA010469 Oryza indica BGIOSGA010469 N
OLONG_027628 Oryza longistaminata OLONG_027628 I
OPUNC03G21190 Oryza punctata OPUNC03G21190 N
OPUNC12G15600 Oryza punctata OPUNC12G15600 I
ORUFI03G23240 Oryza rufipogon ORUFI03G23240 I
OS03G0437200 Oryza sativa OS03G0437200 I
OS11G0340477 Oryza sativa OS11G0340477 N
OS12G0583700 Oryza sativa OS12G0583700 I
OS03G0437100 Oryza sativa OS03G0437100 N
PDK_20s1446781g002 Phoenix dactylifera PDK_20s1446781g002 N
gw1.254.15.1 Physcomitrella patens gw1.254.15.1 I
Si037343m.g Setaria italica Si037343m.g N
Si037516m.g Setaria italica Si037516m.g N
Sb01g031920 Sorghum bicolor Sb01g031920 N
Traes_2BS_494F02775 Triticum aestivum Traes_2BS_494F02775 N
Traes_2DS_11ADF414D Triticum aestivum Traes_2DS_11ADF414D N
Traes_4BS_FE945D2FC Triticum aestivum Traes_4BS_FE945D2FC I
GRMZM5G883760 Zea mays GRMZM5G883760 N