OVOL2 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000125850 T094895_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
OVOL2
M00234_2.00		 Homo sapiens
NCCGYTANNN
NNNTARCGGN		 PBM
Barrera et al.(2016)
OVOL2_D228E		 (Direct) (Direct)
OVOL2
M00235_2.00		 Homo sapiens
NCCGYTANNN
NNNTARCGGN		 PBM
Barrera et al.(2016)
OVOL2_REF		 (Direct) (Direct)
OVOL2
M04445_2.00		 Homo sapiens
NNHCCGYTANNHN
NDNNTARCGGDNN		 SELEX
Yin et al.(2017)
OVOL2_eDBD_HT-SELEX		 (Direct) (Direct)
OVOL2
M04446_2.00		 Homo sapiens
NNWCCGTTANNHN
NDNNTAACGGWNN		 SELEX
Yin et al.(2017)
OVOL2_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
OVOL2
M04447_2.00		 Homo sapiens
DDWCCGTTABNHN
NDNVTAACGGWHH		 SELEX
Yin et al.(2017)
OVOL2_FL_HT-SELEX		 (Direct) (Direct)
OVOL2
M04448_2.00		 Homo sapiens
DDWCCGTTABNHN
NDNVTAACGGWHH		 SELEX
Yin et al.(2017)
OVOL2_FL_Methyl-HT-SELEX		 (Direct) (Direct)
OVOL2
M10207_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MOVOB_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Ovol2
M08993_2.00 		Mus musculus
HCCGTTAN
NTAACGGD		 Misc
Kulakovskiy et al.(2013)
OVOL2_MOUSE.H11MO.0.C 		0.813 0.967
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00234_2.00 C2H2 ZF 15 37
M00234_2.00 C2H2 ZF 43 65
M00234_2.00 C2H2 ZF 71 94
M00234_2.00 C2H2 ZF 110 133
M00235_2.00 C2H2 ZF 15 37
M00235_2.00 C2H2 ZF 43 65
M00235_2.00 C2H2 ZF 71 94
M00235_2.00 C2H2 ZF 110 133

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000278780 C2H2 ZF 119 141
ENSP00000278780 C2H2 ZF 147 169
ENSP00000278780 C2H2 ZF 175 198
ENSP00000278780 C2H2 ZF 214 237

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

54 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
gw1.00626.12.1 Aspergillus carbonarius gw1.00626.12.1 I 0.000
CADANGAG00003173 Aspergillus niger CADANGAG00003173 I 0.000
EURHEDRAFT_382983 Aspergillus ruber EURHEDRAFT_382983 I 0.000
BDDG_05885 Blastomyces dermatitidis BDDG_05885 I 0.000
PVAR5_8008 Byssochlamys spectabilis PVAR5_8008 I 0.000
PV05_09137 Exophiala xenobiotica PV05_09137 I 0.000
PABG_12465 Paracoccidioides brasiliensis PABG_12465 I 0.000
PAAG_11662 Paracoccidioides sp lutzii PAAG_11662 I 0.000
TSTA_050470 Talaromyces stipitatus TSTA_050470 I 0.000