OVOL2 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000125850 T094895_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
OVOL2
M00234_2.00		 Homo sapiens
NCCGYTANNN
NNNTARCGGN		 PBM
Barrera et al.(2016)
OVOL2_D228E		 (Direct) (Direct)
OVOL2
M00235_2.00		 Homo sapiens
NCCGYTANNN
NNNTARCGGN		 PBM
Barrera et al.(2016)
OVOL2_REF		 (Direct) (Direct)
OVOL2
M04445_2.00		 Homo sapiens
NNHCCGYTANNHN
NDNNTARCGGDNN		 SELEX
Yin et al.(2017)
OVOL2_eDBD_HT-SELEX		 (Direct) (Direct)
OVOL2
M04446_2.00		 Homo sapiens
NNWCCGTTANNHN
NDNNTAACGGWNN		 SELEX
Yin et al.(2017)
OVOL2_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
OVOL2
M04447_2.00		 Homo sapiens
DDWCCGTTABNHN
NDNVTAACGGWHH		 SELEX
Yin et al.(2017)
OVOL2_FL_HT-SELEX		 (Direct) (Direct)
OVOL2
M04448_2.00		 Homo sapiens
DDWCCGTTABNHN
NDNVTAACGGWHH		 SELEX
Yin et al.(2017)
OVOL2_FL_Methyl-HT-SELEX		 (Direct) (Direct)
OVOL2
M10207_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MOVOB_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Ovol2
M08993_2.00 		Mus musculus
HCCGTTAN
NTAACGGD		 Misc
Kulakovskiy et al.(2013)
OVOL2_MOUSE.H11MO.0.C 		0.813 0.967
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00234_2.00 C2H2 ZF 15 37
M00234_2.00 C2H2 ZF 43 65
M00234_2.00 C2H2 ZF 71 94
M00234_2.00 C2H2 ZF 110 133
M00235_2.00 C2H2 ZF 15 37
M00235_2.00 C2H2 ZF 43 65
M00235_2.00 C2H2 ZF 71 94
M00235_2.00 C2H2 ZF 110 133

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000278780 C2H2 ZF 119 141
ENSP00000278780 C2H2 ZF 147 169
ENSP00000278780 C2H2 ZF 175 198
ENSP00000278780 C2H2 ZF 214 237

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

54 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSCSAG00000011547 Chlorocebus sabaeus ENSCSAG00000011547 I 0.827
OVOL2 Gorilla gorilla ENSGGOG00000024444 I 0.827
ENSMMUG00000021621 Macaca mulatta ENSMMUG00000021621 I 0.827
ENSNLEG00000009741 Nomascus leucogenys ENSNLEG00000009741 I 0.827
ENSPANG00000025538 Papio anubis ENSPANG00000025538 I 0.827
ENSPPYG00000010732 Pongo abelii ENSPPYG00000010732 I 0.827
OVOL2 Pan troglodytes ENSPTRG00000013280 I 0.827
ENSP00000278780 Macaca fascicularis ENSP00000278780 I 0.827
OVOL2 Equus caballus ENSECAG00000007899 I 0.825
OVOL2 Loxodonta africana ENSLAFG00000010597 I 0.825
ENSMICG00000017455 Microcebus murinus ENSMICG00000017455 I 0.825
ENSMLUG00000026760 Myotis lucifugus ENSMLUG00000026760 I 0.825
OVOL2 Oryctolagus cuniculus ENSOCUG00000012116 I 0.825
OVOL2 Otolemur garnettii ENSOGAG00000030325 I 0.825
Myotis_brandtii_Ovol2_10029083 Myotis brandtii Myotis_brandtii_Ovol2_10029083 I 0.825
Ovol2 Dipodomys ordii ENSDORG00000016697 I 0.822
OVOL2 Pteropus vampyrus ENSPVAG00000001140 I 0.822
ENSSTOG00000024979 Ictidomys tridecemlineatus ENSSTOG00000024979 I 0.822
ENSAMEG00000005266 Ailuropoda melanoleuca ENSAMEG00000005266 I 0.819
OVOL2 Felis catus ENSFCAG00000027530 I 0.819
OVOL2 Monodelphis domestica ENSMODG00000005504 I 0.819
ENSMPUG00000001295 Mustela putorius furo ENSMPUG00000001295 I 0.819
ENSSHAG00000018466 Sarcophilus harrisii ENSSHAG00000018466 I 0.819
OVOL2 Gallus gallus ENSGALG00000008702 I 0.817
ENSMGAG00000006770 Meleagris gallopavo ENSMGAG00000006770 I 0.817
ENSOARG00000018244 Ovis aries ENSOARG00000018244 I 0.817
ENSSARG00000006563 Sorex araneus ENSSARG00000006563 I 0.816
OVOL2 Echinops telfairi ENSETEG00000006907 I 0.815
OVOL2 Ochotona princeps ENSOPRG00000015054 I 0.815
Ovol2 Mus musculus ENSMUSG00000037279 D 0.813
Ovol2 Rattus norvegicus ENSRNOG00000006850 I 0.813
ENSFALG00000007594 Ficedula albicollis ENSFALG00000007594 I 0.812
OVOL2 Taeniopygia guttata ENSTGUG00000005909 I 0.812
Aan_R006310 Calypte anna Aan_R006310 I 0.812
Afo_R007843 Aptenodytes forsteri Afo_R007843 I 0.812
Brh_R002739 Buceros rhinoceros Brh_R002739 I 0.812
Tal_R010801 Tyto alba Tal_R010801 I 0.812
ENSCPOG00000007912 Cavia porcellus ENSCPOG00000007912 I 0.811
ENSAPLG00000016199 Anas platyrhynchos ENSAPLG00000016199 I 0.807
OVOL2 Canis familiaris ENSCAFG00000005453 I 0.807
OVOL2 Bos taurus ENSBTAG00000008410 I 0.805
OVOL2 Tursiops truncatus ENSTTRG00000016430 I 0.805
ENSBTAP00000011067-D1 Bos grunniens ENSBTAP00000011067-D1 I 0.805
ovol2 Xenopus tropicalis XB-GENE-854193 I 0.805
ENSPSIG00000006768 Pelodiscus sinensis ENSPSIG00000006768 I 0.802
ENSOANG00000001250 Ornithorhynchus anatinus ENSOANG00000001250 I 0.797
Alligator_sinensis_CCG008208.1 Alligator sinensis Alligator_sinensis_CCG008208.1 I 0.797
Cmyd_10010114 Chelonia mydas Cmyd_10010114 I 0.797
ENSMEUG00000011922 Macropus eugenii ENSMEUG00000011922 I 0.780
Pvit_03654 Pogona vitticeps Pvit_03654 I 0.774
OVOL2 Callithrix jacchus ENSCJAG00000005049 I 0.767
OVOL2 Anolis carolinensis ENSACAG00000014216 I 0.766
Ogr08372 Ophisaurus gracilis Ogr08372 I 0.763
ENSTSYG00000012790 Tarsius syrichta ENSTSYG00000012790 I 0.762