BHLHE41 (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000123095 T034275_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
BHLHE41
M02782_2.00		 Homo sapiens
NKCACGTGMN
NKCACGTGMN		 SELEX
Jolma et al.(2013)
BHLHB3_1		 (Direct) (Direct)
BHLHE41
M02783_2.00		 Homo sapiens
RKCACGTGAY
RTCACGTGMY		 SELEX
Jolma et al.(2013)
BHLHE41_1		 (Direct) (Direct)
BHLHE41
M04106_2.00		 Homo sapiens
VTCACGTGAB
VTCACGTGAB		 SELEX
Yin et al.(2017)
BHLHE41_eDBD_HT-SELEX		 (Direct) (Direct)
BHLHE41
M04107_2.00		 Homo sapiens
RTCACGTGAY
RTCACGTGAY		 SELEX
Yin et al.(2017)
BHLHE41_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
BHLHE41
M09833_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$DEC2_Q2		 (Direct) (Direct)
BHLHE41
M09834_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$DEC2_Q3		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Bhlhe41
M01739_2.00 		Mus musculus
NMNCGTGMN
NKCACGNKN		 PBM
Weirauch et al.(2014)
pTH5060 		0.914 1.000
Bhlhe40
M00119_2.00 		Mus musculus
DCACGTGMN
NKCACGTGH		 PBM
Badis et al.(2009)
Bhlhb2_1274 		0.914 0.981
Bhlhe40
M01738_2.00 		Mus musculus
NCACRNBN
NVNYGTGN		 PBM
Weirauch et al.(2014)
pTH4330 		0.914 0.981
BHLHE40
M02788_2.00 		Homo sapiens
NKCACGTGMH
DKCACGTGMN		 SELEX
Jolma et al.(2013)
BHLHB2_1 		0.914 0.981
Bhlhe40
M02817_2.00 		Mus musculus
NKCACGTGMN
NKCACGTGMN		 SELEX
Jolma et al.(2013)
Bhlhb2_1 		0.914 0.981
Bhlhe40
M02818_2.00 		Mus musculus
NKCACGTGMN
NKCACGTGMN		 SELEX
Jolma et al.(2013)
Bhlhb2_2 		0.914 0.981
BHLHE40
M04126_2.00 		Homo sapiens
VTCACGTGAB
VTCACGTGAB		 SELEX
Yin et al.(2017)
BHLHE40_eDBD_HT-SELEX 		0.914 0.981
BHLHE40
M07798_2.00 		Homo sapiens
DCACGTGMSN
NSKCACGTGH		 ChIP-seq
Gerstein et al.(2012)
HepG2_BHLHE40_HudsonAlpha 		0.914 0.981
BHLHE40
M08726_2.00 		Homo sapiens
DDCACGTGMS
SKCACGTGHH		 Misc
Kulakovskiy et al.(2013)
BHE40_HUMAN.H11MO.0.A 		0.914 0.981
Bhlhe40
M08761_2.00 		Mus musculus
DCACGTGMS
SKCACGTGH		 Misc
Kulakovskiy et al.(2013)
BHE40_MOUSE.H11MO.0.A 		0.914 0.981
BHLHE40
M09456_2.00 		Homo sapiens
DCACGTGMNN
NNKCACGTGH		 Misc
Heinz et al.(2010)
HepG2-BHLHE40_GSE31477 		0.914 0.981
BHLHE40
M09842_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BHLHE40_03 		0.914 0.981
BHLHE40
M09843_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$DEC1_Q2 		0.914 0.981
BHLHE40
M09844_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$DEC1_Q3 		0.914 0.981
BHLHE40
M09845_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$STRA13_01 		0.914 0.981
BHLHE40
M04127_2.00 		Homo sapiens
RTCACGTGAY
RTCACGTGAY		 SELEX
Yin et al.(2017)
BHLHE40_eDBD_Methyl-HT-SELEX 		0.914 0.981
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000242728 bHLH 46 100

Links

Other bHLH family TFs
Other Homo sapiens TFs

117 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
BHLHE41 Anolis carolinensis ENSACAG00000000432 I 0.914
BHLHE40 Anolis carolinensis ENSACAG00000012577 I 0.914
ENSAMEG00000011905 Ailuropoda melanoleuca ENSAMEG00000011905 I 0.914
ENSAMEG00000016060 Ailuropoda melanoleuca ENSAMEG00000016060 I 0.914
ENSAMXG00000020366 Astyanax mexicanus ENSAMXG00000020366 I 0.914
BHLHE40 Bos taurus ENSBTAG00000009863 I 0.914
BHLHE41 Bos taurus ENSBTAG00000030575 I 0.914
BHLHE40 Canis familiaris ENSCAFG00000005621 I 0.914
ENSCAFG00000031081 Canis familiaris ENSCAFG00000031081 I 0.914
BHLHE40 Callithrix jacchus ENSCJAG00000015832 I 0.914
ENSCPOG00000025122 Cavia porcellus ENSCPOG00000025122 I 0.914
ENSCSAG00000007728 Chlorocebus sabaeus ENSCSAG00000007728 I 0.914
ENSCSAG00000010905 Chlorocebus sabaeus ENSCSAG00000010905 I 0.914
bhlhe41 Danio rerio ENSDARG00000041691 I 0.914
BHLHE40 Dasypus novemcinctus ENSDNOG00000035717 I 0.914
ENSDORG00000006908 Dipodomys ordii ENSDORG00000006908 I 0.914
ENSECAG00000000494 Equus caballus ENSECAG00000000494 I 0.914
BHLHE40 Equus caballus ENSECAG00000015069 I 0.914
BHLHE41 Echinops telfairi ENSETEG00000017468 I 0.914
ENSFALG00000003877 Ficedula albicollis ENSFALG00000003877 I 0.914
ENSFALG00000013572 Ficedula albicollis ENSFALG00000013572 I 0.914
BHLHE40 Felis catus ENSFCAG00000002966 I 0.914
ENSFCAG00000022143 Felis catus ENSFCAG00000022143 I 0.914
BHLHE40 Homo sapiens ENSG00000134107 D 0.914
BHLHE40 Gasterosteus aculeatus ENSGACG00000000659 I 0.914
BHLHE40 Gallus gallus ENSGALG00000008308 I 0.914
BHLHE41 Gorilla gorilla ENSGGOG00000015498 I 0.914
BHLHE40 Gorilla gorilla ENSGGOG00000015864 I 0.914
ENSGMOG00000004494 Gadus morhua ENSGMOG00000004494 I 0.914
ENSLACG00000013163 Latimeria chalumnae ENSLACG00000013163 I 0.914
BHLHE40 Loxodonta africana ENSLAFG00000004896 I 0.914
BHLHE41 Loxodonta africana ENSLAFG00000030711 I 0.914
ENSLOCG00000010962 Lepisosteus oculatus ENSLOCG00000010962 I 0.914
ENSLOCG00000015327 Lepisosteus oculatus ENSLOCG00000015327 I 0.914
ENSMEUG00000010801 Macropus eugenii ENSMEUG00000010801 I 0.914
ENSMEUG00000013058 Macropus eugenii ENSMEUG00000013058 I 0.914
BHLHE41 Myotis lucifugus ENSMLUG00000028371 I 0.914
ENSMMUG00000014588 Macaca mulatta ENSMMUG00000014588 I 0.914
ENSMMUG00000018629 Macaca mulatta ENSMMUG00000018629 I 0.914
BHLHE40 Monodelphis domestica ENSMODG00000004516 I 0.914
BHLHE41 Monodelphis domestica ENSMODG00000016551 I 0.914
ENSMPUG00000010346 Mustela putorius furo ENSMPUG00000010346 I 0.914
ENSMPUG00000017029 Mustela putorius furo ENSMPUG00000017029 I 0.914
Bhlhe40 Mus musculus ENSMUSG00000030103 D 0.914
Bhlhe41 Mus musculus ENSMUSG00000030256 D 0.914
ENSNLEG00000003704 Nomascus leucogenys ENSNLEG00000003704 I 0.914
ENSNLEG00000005307 Nomascus leucogenys ENSNLEG00000005307 I 0.914
BHLHE40 Ornithorhynchus anatinus ENSOANG00000003764 I 0.914
ENSOARG00000007840 Ovis aries ENSOARG00000007840 I 0.914
ENSOARG00000019968 Ovis aries ENSOARG00000019968 I 0.914
BHLHE40 Oryctolagus cuniculus ENSOCUG00000015177 I 0.914
BHLHE40 Otolemur garnettii ENSOGAG00000029762 I 0.914
ENSOGAG00000032001 Otolemur garnettii ENSOGAG00000032001 I 0.914
ENSONIG00000019148 Oreochromis niloticus ENSONIG00000019148 I 0.914
ENSOPRG00000009637 Ochotona princeps ENSOPRG00000009637 I 0.914
dec1b Oryzias latipes ENSORLG00000014397 I 0.914
ENSPANG00000006688 Papio anubis ENSPANG00000006688 I 0.914
ENSPANG00000008563 Papio anubis ENSPANG00000008563 I 0.914
ENSPFOG00000007800 Poecilia formosa ENSPFOG00000007800 I 0.914
ENSPPYG00000004372 Pongo abelii ENSPPYG00000004372 I 0.914
ENSPPYG00000013696 Pongo abelii ENSPPYG00000013696 I 0.914
ENSPSIG00000016504 Pelodiscus sinensis ENSPSIG00000016504 I 0.914
ENSPSIG00000018157 Pelodiscus sinensis ENSPSIG00000018157 I 0.914
BHLHE41 Pan troglodytes ENSPTRG00000004779 I 0.914
BHLHE40 Pan troglodytes ENSPTRG00000014571 I 0.914
BHLHE41 Pteropus vampyrus ENSPVAG00000004507 I 0.914
BHLHE40 Pteropus vampyrus ENSPVAG00000007723 I 0.914
Bhlhe40 Rattus norvegicus ENSRNOG00000007152 I 0.914
Bhlhe41 Rattus norvegicus ENSRNOG00000048961 I 0.914
ENSSSCG00000011534 Sus scrofa ENSSSCG00000011534 I 0.914
BHLHE41 Sus scrofa ENSSSCG00000028552 I 0.914
ENSSTOG00000000793 Ictidomys tridecemlineatus ENSSTOG00000000793 I 0.914
ENSSTOG00000021007 Ictidomys tridecemlineatus ENSSTOG00000021007 I 0.914
ENSTGUG00000012230 Taeniopygia guttata ENSTGUG00000012230 I 0.914
BHLHE40 Takifugu rubripes ENSTRUG00000011390 I 0.914
ENSTSYG00000002535 Tarsius syrichta ENSTSYG00000002535 I 0.914
BHLHE40 Tursiops truncatus ENSTTRG00000002786 I 0.914
BHLHE41 Tursiops truncatus ENSTTRG00000014501 I 0.914
ENSXMAG00000002248 Xiphophorus maculatus ENSXMAG00000002248 I 0.914
Aan_R007938 Calypte anna Aan_R007938 I 0.914
Alligator_sinensis_CCG021907.1 Alligator sinensis Alligator_sinensis_CCG021907.1 I 0.914
Cmyd_10013122 Chelonia mydas Cmyd_10013122 I 0.914
Cmyd_10013769 Chelonia mydas Cmyd_10013769 I 0.914
ENSBTAP00000040772-D1 Bos grunniens ENSBTAP00000040772-D1 I 0.914
ENSMMUP00000024507 Macaca fascicularis ENSMMUP00000024507 I 0.914
ENSP00000256495-D1 Bos grunniens ENSP00000256495-D1 I 0.914
ENSP00000256495 Macaca fascicularis ENSP00000256495 I 0.914
Gfo_R015175 Geospiza fortis Gfo_R015175 I 0.914
Myotis_brandtii_BHLHE40_10019553 Myotis brandtii Myotis_brandtii_BHLHE40_10019553 I 0.914
Myotis_brandtii_BHLHE41_10027341 Myotis brandtii Myotis_brandtii_BHLHE41_10027341 I 0.914
Pvit_15832 Pogona vitticeps Pvit_15832 I 0.914
Pvit_19380 Pogona vitticeps Pvit_19380 I 0.914
bhlhe41 Xenopus tropicalis XB-GENE-994875 I 0.914
ENSNLEG00000026535 Nomascus leucogenys ENSNLEG00000026535 I 0.894
ENSAMXG00000007020 Astyanax mexicanus ENSAMXG00000007020 I 0.890
bhlhe40 Danio rerio ENSDARG00000004060 I 0.890
bhlhe40 Gasterosteus aculeatus ENSGACG00000011940 I 0.890
ENSGMOG00000002353 Gadus morhua ENSGMOG00000002353 I 0.890
ENSONIG00000020277 Oreochromis niloticus ENSONIG00000020277 I 0.890
dec1a Oryzias latipes ENSORLG00000012739 I 0.890
ENSPFOG00000004275 Poecilia formosa ENSPFOG00000004275 I 0.890
bhlhe40 Tetraodon nigroviridis ENSTNIG00000007338 I 0.890
bhlhe40 Takifugu rubripes ENSTRUG00000014524 I 0.890
ENSXMAG00000008981 Xiphophorus maculatus ENSXMAG00000008981 I 0.890
bhlhe40.S Xenopus laevis XB-GENE-17337587 I 0.890
bhlhe40 Xenopus tropicalis XB-GENE-486416 I 0.890
bhlhe40.L Xenopus laevis XB-GENE-865608 I 0.890
bhlhe41 Gasterosteus aculeatus ENSGACG00000011684 I 0.889
ENSONIG00000014711 Oreochromis niloticus ENSONIG00000014711 I 0.889
bhlhe41 Oryzias latipes ENSORLG00000011401 I 0.889
ENSPFOG00000015542 Poecilia formosa ENSPFOG00000015542 I 0.889
ENSPMAG00000003684 Petromyzon marinus ENSPMAG00000003684 I 0.889
bhlhe41 Tetraodon nigroviridis ENSTNIG00000012152 I 0.889
bhlhe41 Takifugu rubripes ENSTRUG00000005639 I 0.889
ENSXMAG00000001113 Xiphophorus maculatus ENSXMAG00000001113 I 0.889
Afo_R006295 Aptenodytes forsteri Afo_R006295 I 0.889
ENSGMOG00000003444 Gadus morhua ENSGMOG00000003444 I 0.858