CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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HAND2
(
Homo sapiens
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00010 (HLH)
IPR001092
ENSG00000164107
T034305_2.00
Ensembl (2018-Dec-8)
Link out
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
HAND2
M04150_2.00
Homo sapiens
MACACCTGBD
HVCAGGTGTK
SELEX
Yin et al.(2017)
HAND2_eDBD_HT-SELEX
(Direct)
(Direct)
HAND2
M04151_2.00
Homo sapiens
MACACCTGYD
HRCAGGTGTK
SELEX
Yin et al.(2017)
HAND2_eDBD_Methyl-HT-SELEX
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Hand1
M08769_2.00
Mus musculus
WGABRNWDNSCAGRNNH
DNNYCTGSNHWNYVTCW
Misc
Kulakovskiy et al.(2013)
HAND1_MOUSE.H11MO.0.C
0.393
1.000
For this family, TFs with SR scores >
0.838
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000352565
bHLH
100
152
RRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLM
ENSP00000427084
bHLH
2
27
PNVPADTKLSKIKTLRLATSYIAYLM
ENSP00000477638
bHLH
69
121
ASGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLM
Links
Other
bHLH
family TFs
Other
Homo sapiens
TFs
148 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
ENSAMEG00000014235
Ailuropoda melanoleuca
ENSAMEG00000014235
I
0.914
HAND2
Bos taurus
ENSBTAG00000044123
I
0.914
HAND2
Canis familiaris
ENSCAFG00000007858
I
0.914
HAND2
Callithrix jacchus
ENSCJAG00000005144
I
0.914
ENSCPOG00000001740
Cavia porcellus
ENSCPOG00000001740
I
0.914
ENSCSAG00000003094
Chlorocebus sabaeus
ENSCSAG00000003094
I
0.914
hand2
Danio rerio
ENSDARG00000008305
I
0.914
HAND2
Dasypus novemcinctus
ENSDNOG00000035702
I
0.914
Hand2
Dipodomys ordii
ENSDORG00000007304
I
0.914
HAND2
Equus caballus
ENSECAG00000009657
I
0.914
ENSFALG00000011490
Ficedula albicollis
ENSFALG00000011490
I
0.914
HAND2
Felis catus
ENSFCAG00000031585
I
0.914
hand2
Gasterosteus aculeatus
ENSGACG00000016418
I
0.914
HAND2
Gorilla gorilla
ENSGGOG00000006147
I
0.914
ENSGMOG00000018978
Gadus morhua
ENSGMOG00000018978
I
0.914
ENSLACG00000004329
Latimeria chalumnae
ENSLACG00000004329
I
0.914
HAND2
Loxodonta africana
ENSLAFG00000029843
I
0.914
ENSLOCG00000013581
Lepisosteus oculatus
ENSLOCG00000013581
I
0.914
ENSMEUG00000010715
Macropus eugenii
ENSMEUG00000010715
I
0.914
HAND2
Myotis lucifugus
ENSMLUG00000002599
I
0.914
ENSMMUG00000018749
Macaca mulatta
ENSMMUG00000018749
I
0.914
HAND2
Monodelphis domestica
ENSMODG00000003548
I
0.914
ENSMPUG00000001909
Mustela putorius furo
ENSMPUG00000001909
I
0.914
Hand2
Mus musculus
ENSMUSG00000038193
I
0.914
ENSNLEG00000006670
Nomascus leucogenys
ENSNLEG00000006670
I
0.914
ENSOARG00000015352
Ovis aries
ENSOARG00000015352
I
0.914
ENSOCUG00000016256
Oryctolagus cuniculus
ENSOCUG00000016256
I
0.914
HAND2
Otolemur garnettii
ENSOGAG00000027928
I
0.914
ENSONIG00000016059
Oreochromis niloticus
ENSONIG00000016059
I
0.914
HAND2
Ochotona princeps
ENSOPRG00000010154
I
0.914
hand2
Oryzias latipes
ENSORLG00000010967
I
0.914
ENSPANG00000023378
Papio anubis
ENSPANG00000023378
I
0.914
ENSPFOG00000009546
Poecilia formosa
ENSPFOG00000009546
I
0.914
ENSPPYG00000015208
Pongo abelii
ENSPPYG00000015208
I
0.914
HAND2
Pan troglodytes
ENSPTRG00000016601
I
0.914
ENSSHAG00000011188
Sarcophilus harrisii
ENSSHAG00000011188
I
0.914
ENSSSCG00000009703
Sus scrofa
ENSSSCG00000009703
I
0.914
ENSSTOG00000023020
Ictidomys tridecemlineatus
ENSSTOG00000023020
I
0.914
HAND2
Tupaia belangeri
ENSTBEG00000007591
I
0.914
HAND2
Taeniopygia guttata
ENSTGUG00000006281
I
0.914
hand2
Tetraodon nigroviridis
ENSTNIG00000005584
I
0.914
HAND2
Tursiops truncatus
ENSTTRG00000001365
I
0.914
HAND2
Vicugna pacos
ENSVPAG00000006724
I
0.914
ENSXMAG00000015868
Xiphophorus maculatus
ENSXMAG00000015868
I
0.914
Aan_R004859
Calypte anna
Aan_R004859
I
0.914
Alligator_sinensis_CCG007905.1
Alligator sinensis
Alligator_sinensis_CCG007905.1
I
0.914
Cmyd_10016492
Chelonia mydas
Cmyd_10016492
I
0.914
ENSP00000352565-D1
Bos grunniens
ENSP00000352565-D1
I
0.914
Gfo_R010505
Geospiza fortis
Gfo_R010505
I
0.914
Ogr14661
Ophisaurus gracilis
Ogr14661
I
0.914
e_gw.829.7.1
Branchiostoma floridae
e_gw.829.7.1
I
0.914
estExt_fgenesh2_pm.C_20027
Branchiostoma floridae
estExt_fgenesh2_pm.C_20027
I
0.914
hand2
Xenopus tropicalis
XB-GENE-481426
I
0.914
hand2.S
Xenopus laevis
XB-GENE-6252408
I
0.914
HAND2
Microcebus murinus
ENSMICG00000009054
I
0.911
ISCW009436
Ixodes scapularis
ISCW009436
I
0.894
L798_02599
Zootermopsis nevadensis
L798_02599
I
0.894
PHUM088400
Pediculus humanus
PHUM088400
I
0.894
ENSAMXG00000025833
Astyanax mexicanus
ENSAMXG00000025833
I
0.890
ENSLOCG00000012444
Lepisosteus oculatus
ENSLOCG00000012444
I
0.890
hand2.L
Xenopus laevis
XB-GENE-865126
I
0.890
Sakowv30003804m.g
Saccoglossus kowalevskii
Sakowv30003804m.g
I
0.886
GB46056
Apis mellifera
GB46056
I
0.883
NV12516
Nasonia vitripennis
NV12516
I
0.883
Cflo_05798--XP_001122645.1_APIME
Camponotus floridanus
Cflo_05798--XP_001122645.1_APIME
I
0.883
Hsal_12649--XP_001122645.1_APIME
Harpegnathos saltator
Hsal_12649--XP_001122645.1_APIME
I
0.883
RPRC005573
Rhodnius prolixus
RPRC005573
I
0.870
ACYPI009244
Acyrthosiphon pisum
ACYPI009244
I
0.866
CGI_10023955
Crassostrea gigas
CGI_10023955
I
0.866
Ocbimv22024043m.g
Octopus bimaculoides
Ocbimv22024043m.g
I
0.866
HHAL010291-PA
Halyomorpha halys
HHAL010291-PA
I
0.866
LotgiG104540
Lottia gigantea
LotgiG104540
I
0.862
SMAR011914
Strigamia maritima
SMAR011914
I
0.862
SMAR012521
Strigamia maritima
SMAR012521
I
0.862
tetur18g03540
Tetranychus urticae
tetur18g03540
I
0.862
LLOJ007342
Lutzomyia longipalpis
LLOJ007342
I
0.862
PPAI010228
Phlebotomus papatasi
PPAI010228
I
0.862
ACEP24088
Atta cephalotes
ACEP24088
I
0.855
SINV12583
Solenopsis invicta
SINV12583
I
0.855
CLEC007932
Cimex lectularius
CLEC007932
I
0.852
CpipJ_CPIJ009732
Culex pipiens
CpipJ_CPIJ009732
I
0.839
AAEL002423
Aedes aegypti
AAEL002423
I
0.839
AGAP004386
Anopheles gambiae
AGAP004386
I
0.839
CPIJ009732
Culex quinquefasciatus
CPIJ009732
I
0.839
ENSPSIG00000012804
Pelodiscus sinensis
ENSPSIG00000012804
N
0.839
AALB002515
Anopheles albimanus
AALB002515
I
0.839
AARA005336
Anopheles arabiensis
AARA005336
I
0.839
AATE010223
Anopheles atroparvus
AATE010223
I
0.839
ACHR001840
Anopheles christyi
ACHR001840
I
0.839
ACOM029750
Anopheles coluzzii
ACOM029750
I
0.839
ACUA000831
Anopheles culicifacies
ACUA000831
I
0.839
ADIR005442
Anopheles dirus
ADIR005442
I
0.839
AEPI007770
Anopheles epiroticus
AEPI007770
I
0.839
AFAF019328
Anopheles farauti
AFAF019328
I
0.839
AFUN005909
Anopheles funestus
AFUN005909
I
0.839
AMAM001941
Anopheles maculatus
AMAM001941
I
0.839
AMEC002742
Anopheles melas
AMEC002742
I
0.839
AMEM001490
Anopheles merus
AMEM001490
I
0.839
AMIN004773
Anopheles minimus
AMIN004773
I
0.839
AQUA008454
Anopheles quadriannulatus
AQUA008454
I
0.839
ASIS021599
Anopheles sinensis
ASIS021599
I
0.839
ASTEI10695
Anopheles stephensi
ASTEI10695
I
0.839
Pvit_12366
Pogona vitticeps
Pvit_12366
I
0.583
ENSMICG00000003569
Microcebus murinus
ENSMICG00000003569
I
0.530
Ogr18916
Ophisaurus gracilis
Ogr18916
N
0.530
HAND2
Anolis carolinensis
ENSACAG00000005500
N
0.393
ENSAMEG00000016692
Ailuropoda melanoleuca
ENSAMEG00000016692
I
0.393
HAND1
Bos taurus
ENSBTAG00000002335
I
0.393
HAND1
Canis familiaris
ENSCAFG00000017641
I
0.393
HAND1
Callithrix jacchus
ENSCJAG00000009817
I
0.393
HAND1
Cavia porcellus
ENSCPOG00000024064
I
0.393
ENSCSAG00000010805
Chlorocebus sabaeus
ENSCSAG00000010805
I
0.393
HAND1
Dasypus novemcinctus
ENSDNOG00000007934
I
0.393
Hand1
Dipodomys ordii
ENSDORG00000015170
I
0.393
HAND1
Equus caballus
ENSECAG00000005327
I
0.393
HAND1
Echinops telfairi
ENSETEG00000010988
I
0.393
HAND1
Felis catus
ENSFCAG00000014986
I
0.393
HAND1
Homo sapiens
ENSG00000113196
I
0.393
HAND1
Gasterosteus aculeatus
ENSGACG00000020816
I
0.393
HAND1
Gorilla gorilla
ENSGGOG00000004311
I
0.393
ENSLACG00000018666
Latimeria chalumnae
ENSLACG00000018666
I
0.393
HAND1
Loxodonta africana
ENSLAFG00000017517
I
0.393
HAND1
Myotis lucifugus
ENSMLUG00000008901
I
0.393
HAND1
Macaca mulatta
ENSMMUG00000010621
I
0.393
ENSMPUG00000013570
Mustela putorius furo
ENSMPUG00000013570
I
0.393
Hand1
Mus musculus
ENSMUSG00000037335
D
0.393
ENSNLEG00000016584
Nomascus leucogenys
ENSNLEG00000016584
I
0.393
ENSOARG00000009843
Ovis aries
ENSOARG00000009843
I
0.393
HAND1
Oryctolagus cuniculus
ENSOCUG00000011099
I
0.393
HAND1
Otolemur garnettii
ENSOGAG00000024691
I
0.393
HAND1
Ochotona princeps
ENSOPRG00000014560
I
0.393
ENSPANG00000013720
Papio anubis
ENSPANG00000013720
I
0.393
HAND1
Procavia capensis
ENSPCAG00000006706
I
0.393
ENSPPYG00000015975
Pongo abelii
ENSPPYG00000015975
I
0.393
HAND1
Pan troglodytes
ENSPTRG00000017446
I
0.393
HAND1
Pteropus vampyrus
ENSPVAG00000002261
I
0.393
Hand1
Rattus norvegicus
ENSRNOG00000002582
I
0.393
Hand2
Rattus norvegicus
ENSRNOG00000060448
N
0.393
ENSSSCG00000017070
Sus scrofa
ENSSSCG00000017070
I
0.393
ENSSTOG00000025850
Ictidomys tridecemlineatus
ENSSTOG00000025850
I
0.393
HAND1
Tetraodon nigroviridis
ENSTNIG00000007631
I
0.393
HAND1
Takifugu rubripes
ENSTRUG00000003992
I
0.393
HAND1
Tursiops truncatus
ENSTTRG00000002725
I
0.393
Alligator_sinensis_CCG014990.1
Alligator sinensis
Alligator_sinensis_CCG014990.1
I
0.393
ENSP00000231121
Macaca fascicularis
ENSP00000231121
I
0.393
Myotis_brandtii_HAND1_10034795
Myotis brandtii
Myotis_brandtii_HAND1_10034795
I
0.393
Pvit_10616
Pogona vitticeps
Pvit_10616
N
0.393