Ascl1 (Mus musculus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSMUSG00000020052 T035672_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Ascl1
M08748_2.00		 Mus musculus
BHSCASCTGCYBBN
NVVRGCAGSTGSDV		 Misc
Kulakovskiy et al.(2013)
ASCL1_MOUSE.H11MO.0.A		 (Direct) (Direct)
Ascl1
M09464_2.00		 Mus musculus
NVCABCTGBBNN
NNVVCAGVTGBN		 Misc
Heinz et al.(2010)
NeuralTubes-Ascl1_GSE55840		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ASCL1
M04135_2.00 		Homo sapiens
NRCASSTGYN
NRCASSTGYN		 SELEX
Yin et al.(2017)
ASCL1_eDBD_HT-SELEX 		0.914 1.000
ASCL1
M08055_2.00 		Homo sapiens
NNRGCAGCTGSNN
NNSCAGCTGCYNN		 ChIP-seq
Mathelier et al.(2014)
MA1100.1 		0.914 1.000
ASCL1
M08730_2.00 		Homo sapiens
NNVCASCTGCYBYN
NRVRGCAGSTGBNN		 Misc
Kulakovskiy et al.(2013)
ASCL1_HUMAN.H11MO.0.A 		0.914 1.000
ASCL1
M09855_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MASH1_Q6_01 		0.914 1.000
ASCL1
M09856_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MASH1_Q6_02 		0.914 1.000
ASCL1
M09857_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MASH1_Q6 		0.914 1.000
ASCL1
M04136_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL1_eDBD_Methyl-HT-SELEX 		0.914 1.000
Ascl2
M00117_2.00 		Mus musculus
NVCABVTGBN
NVCABVTGBN		 PBM
Badis et al.(2009)
Ascl2_2654 		0.871 0.880
Ascl2
M02814_2.00 		Mus musculus
RRCAGCTGYY
RRCAGCTGYY		 SELEX
Jolma et al.(2013)
Ascl2_1 		0.871 0.880
Ascl2
M08744_2.00 		Mus musculus
RGCAGSTGB
VCASCTGCY		 Misc
Kulakovskiy et al.(2013)
ASCL2_MOUSE.H11MO.0.C 		0.871 0.880
ASCL2
M04207_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL2_eDBD_HT-SELEX 		0.871 0.860
ASCL2
M04209_2.00 		Homo sapiens
VCACRACGCD
HGCGTYGTGB		 SELEX
Yin et al.(2017)
ASCL2_FL_HT-SELEX_1 		0.871 0.860
ASCL2
M04210_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL2_FL_HT-SELEX_2 		0.871 0.860
ASCL2
M04208_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL2_eDBD_Methyl-HT-SELEX 		0.871 0.860
ASCL2
M04211_2.00 		Homo sapiens
VRCAGCTGYB
VRCAGCTGYB		 SELEX
Yin et al.(2017)
ASCL2_FL_Methyl-HT-SELEX 		0.871 0.860
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000020243 bHLH 116 166

Links

Other bHLH family TFs
Other Mus musculus TFs

87 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000006449 Ailuropoda melanoleuca ENSAMEG00000006449 I 0.914
ASCL1 Bos taurus ENSBTAG00000016227 I 0.914
ASCL1 Canis familiaris ENSCAFG00000007324 I 0.914
ASCL1 Callithrix jacchus ENSCJAG00000014345 I 0.914
ASCL1 Cavia porcellus ENSCPOG00000020666 I 0.914
ENSCSAG00000018938 Chlorocebus sabaeus ENSCSAG00000018938 I 0.914
ASCL1 Dasypus novemcinctus ENSDNOG00000001616 I 0.914
ASCL1 Felis catus ENSFCAG00000008250 I 0.914
ASCL1 Homo sapiens ENSG00000139352 D 0.914
ASCL1 Gorilla gorilla ENSGGOG00000005479 I 0.914
ENSMEUG00000010370 Macropus eugenii ENSMEUG00000010370 I 0.914
ASCL1 Macaca mulatta ENSMMUG00000005747 I 0.914
ASCL1 Monodelphis domestica ENSMODG00000002347 I 0.914
ENSNLEG00000006410 Nomascus leucogenys ENSNLEG00000006410 I 0.914
ASCL1 Ornithorhynchus anatinus ENSOANG00000013973 I 0.914
ENSOARG00000015879 Ovis aries ENSOARG00000015879 I 0.914
ASCL1 Oryctolagus cuniculus ENSOCUG00000006992 I 0.914
ASCL1 Otolemur garnettii ENSOGAG00000030324 I 0.914
ENSPPYG00000004884 Pongo abelii ENSPPYG00000004884 I 0.914
ASCL1 Pteropus vampyrus ENSPVAG00000011272 I 0.914
Ascl1 Rattus norvegicus ENSRNOG00000004294 I 0.914
ENSSHAG00000011936 Sarcophilus harrisii ENSSHAG00000011936 I 0.914
ENSSTOG00000028420 Ictidomys tridecemlineatus ENSSTOG00000028420 I 0.914
ASCL1 Tursiops truncatus ENSTTRG00000016243 I 0.914
ASCL1 Vicugna pacos ENSVPAG00000002018 I 0.914
ENSBTAP00000021592-D1 Bos grunniens ENSBTAP00000021592-D1 I 0.914
ENSP00000266744 Macaca fascicularis ENSP00000266744 I 0.914
Ogr07565 Ophisaurus gracilis Ogr07565 I 0.914
Pvit_15764 Pogona vitticeps Pvit_15764 I 0.914
ascl1 Xenopus tropicalis XB-GENE-1032967 I 0.914
ascl1.L Xenopus laevis XB-GENE-1032969 I 0.914
ascl1.S Xenopus laevis XB-GENE-17340658 I 0.914
ascl1a Danio rerio ENSDARG00000038386 I 0.894
ascl1a Gasterosteus aculeatus ENSGACG00000020048 I 0.894
ENSGMOG00000002268 Gadus morhua ENSGMOG00000002268 I 0.894
ENSLACG00000010712 Latimeria chalumnae ENSLACG00000010712 I 0.894
ENSONIG00000021219 Oreochromis niloticus ENSONIG00000021219 I 0.894
ascl1a Oryzias latipes ENSORLG00000016504 I 0.894
ENSPFOG00000018073 Poecilia formosa ENSPFOG00000018073 I 0.894
ascl1a Takifugu rubripes ENSTRUG00000012801 I 0.894
ENSXMAG00000019614 Xiphophorus maculatus ENSXMAG00000019614 I 0.894
ENSLACG00000001911 Latimeria chalumnae ENSLACG00000001911 I 0.886
SMAR011494 Strigamia maritima SMAR011494 I 0.886
ENSAMEG00000002164 Ailuropoda melanoleuca ENSAMEG00000002164 I 0.871
ASCL2 Bos taurus ENSBTAG00000026769 I 0.871
ASCL2 Canis familiaris ENSCAFG00000010103 I 0.871
ASCL2 Callithrix jacchus ENSCJAG00000011549 I 0.871
ENSCPOG00000023523 Cavia porcellus ENSCPOG00000023523 I 0.871
ENSCSAG00000018956 Chlorocebus sabaeus ENSCSAG00000018956 I 0.871
ASCL2 Felis catus ENSFCAG00000018914 I 0.871
ASCL2 Homo sapiens ENSG00000183734 D 0.871
ASCL2 Gorilla gorilla ENSGGOG00000007421 I 0.871
ASCL2 Loxodonta africana ENSLAFG00000020947 I 0.871
ASCL2 Macaca mulatta ENSMMUG00000001322 I 0.871
ENSMPUG00000019849 Mustela putorius furo ENSMPUG00000019849 I 0.871
Ascl2 Mus musculus ENSMUSG00000009248 D 0.871
ENSNLEG00000002663 Nomascus leucogenys ENSNLEG00000002663 I 0.871
ASCL2 Otolemur garnettii ENSOGAG00000034847 I 0.871
ASCL2 Ochotona princeps ENSOPRG00000019165 I 0.871
ENSPANG00000019205 Papio anubis ENSPANG00000019205 I 0.871
ASCL2 Procavia capensis ENSPCAG00000000676 I 0.871
ENSPPYG00000002926 Pongo abelii ENSPPYG00000002926 I 0.871
ASCL2 Pan troglodytes ENSPTRG00000003174 I 0.871
ASCL2 Pteropus vampyrus ENSPVAG00000002964 I 0.871
Ascl2 Rattus norvegicus ENSRNOG00000020434 I 0.871
ENSSTOG00000028167 Ictidomys tridecemlineatus ENSSTOG00000028167 I 0.871
ENSAMXG00000014210 Astyanax mexicanus ENSAMXG00000014210 I 0.864
SPU_028148 Strongylocentrotus purpuratus SPU_028148 I 0.864
Sakowv30008499m.g Saccoglossus kowalevskii Sakowv30008499m.g I 0.864
ENSFALG00000014466 Ficedula albicollis ENSFALG00000014466 I 0.860
ASCL2 Taeniopygia guttata ENSTGUG00000009283 I 0.860
ENSAMXG00000024858 Astyanax mexicanus ENSAMXG00000024858 I 0.859
ascl1b Danio rerio ENSDARG00000101628 I 0.859
ascl1b Gasterosteus aculeatus ENSGACG00000011375 I 0.859
ENSGMOG00000009589 Gadus morhua ENSGMOG00000009589 I 0.859
ENSLOCG00000017318 Lepisosteus oculatus ENSLOCG00000017318 I 0.859
ENSONIG00000020440 Oreochromis niloticus ENSONIG00000020440 I 0.859
ascl1b Oryzias latipes ENSORLG00000012117 I 0.859
ENSPFOG00000020633 Poecilia formosa ENSPFOG00000020633 I 0.859
ascl1b Tetraodon nigroviridis ENSTNIG00000011380 I 0.859
ascl1b Takifugu rubripes ENSTRUG00000011651 I 0.859
ENSXMAG00000019890 Xiphophorus maculatus ENSXMAG00000019890 I 0.859
ENSAMXG00000025568 Astyanax mexicanus ENSAMXG00000025568 I 0.849
ENSGALG00000023607 Gallus gallus ENSGALG00000023607 I 0.847
e_gw.302.11.1 Branchiostoma floridae e_gw.302.11.1 I 0.842
e_gw.59.47.1 Branchiostoma floridae e_gw.59.47.1 I 0.842
ENSAPLG00000001445 Anas platyrhynchos ENSAPLG00000001445 I 0.666