Atf4 (Mus musculus)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSMUSG00000042406 T060486_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Atf4
M00759_2.00		 Mus musculus
NNNNKRCDHVHNN
NNDBDHGYMNNNN		 PBM
Weirauch et al.(2013)
pTH1014		 (Direct) (Direct)
Atf4
M02865_2.00		 Mus musculus
DRBATGAYGCAATM
KATTGCRTCATVYH		 SELEX
Jolma et al.(2013)
Atf4_1		 (Direct) (Direct)
Atf4
M08833_2.00		 Mus musculus
DNMTGATGCAAY
RTTGCATCAKNH		 Misc
Kulakovskiy et al.(2013)
ATF4_MOUSE.H11MO.0.A		 (Direct) (Direct)
Atf4
M09496_2.00		 Mus musculus
MTGATGYAAY
RTTRCATCAK		 Misc
Heinz et al.(2010)
MEF-Atf4_GSE35681		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ATF4
M02834_2.00 		Homo sapiens
DNMTGAYGCAAYM
KRTTGCRTCAKNH		 SELEX
Jolma et al.(2013)
ATF4_1 		0.914 0.984
ATF4
M04274_2.00 		Homo sapiens
RDATGACGTCATHY
RDATGACGTCATHY		 SELEX
Yin et al.(2017)
ATF4_eDBD_HT-SELEX 		0.914 0.984
ATF4
M04276_2.00 		Homo sapiens
RKATGACGTCATMY
RKATGACGTCATMY		 SELEX
Yin et al.(2017)
ATF4_FL_HT-SELEX 		0.914 0.984
ATF4
M04027_2.00 		Homo sapiens
VNATGACGTCABNY
RNVTGACGTCATNB		 SELEX
Rodriguez-Martinez et al.(2017)
ATF4.1 		0.914 0.984
ATF4
M08796_2.00 		Homo sapiens
DNMTGATGCAAY
RTTGCATCAKNH		 Misc
Kulakovskiy et al.(2013)
ATF4_HUMAN.H11MO.0.A 		0.914 0.984
ATF4
M09963_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ATF4_Q2 		0.914 0.984
ATF4
M09964_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ATF4_Q5 		0.914 0.984
ATF4
M09965_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ATF4_Q6 		0.914 0.984
ATF4
M04275_2.00 		Homo sapiens
RKATGACATCATCY
RGATGATGTCATMY		 SELEX
Yin et al.(2017)
ATF4_eDBD_Methyl-HT-SELEX 		0.914 0.984
For this family, TFs with SR scores > 0.782 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00759_2.00 bZIP 16 79

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000105234 bZIP 274 337

Links

Other bZIP family TFs
Other Mus musculus TFs

81 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000010932 Ailuropoda melanoleuca ENSAMEG00000010932 I 0.914
ATF4 Bos taurus ENSBTAG00000017462 I 0.914
ATF4 Canis familiaris ENSCAFG00000001324 I 0.914
ATF4 Choloepus hoffmanni ENSCHOG00000008739 I 0.914
ATF4 Callithrix jacchus ENSCJAG00000002594 I 0.914
ATF4 Cavia porcellus ENSCPOG00000022485 I 0.914
ENSCSAG00000006330 Chlorocebus sabaeus ENSCSAG00000006330 I 0.914
ENSDNOG00000030854 Dasypus novemcinctus ENSDNOG00000030854 I 0.914
ENSDNOG00000046837 Dasypus novemcinctus ENSDNOG00000046837 I 0.914
Atf4 Dipodomys ordii ENSDORG00000004952 I 0.914
ATF4 Equus caballus ENSECAG00000006931 I 0.914
ATF4 Felis catus ENSFCAG00000009288 I 0.914
ATF4 Homo sapiens ENSG00000128272 D 0.914
ENSGGOG00000010115 Gorilla gorilla ENSGGOG00000010115 I 0.914
ATF4 Loxodonta africana ENSLAFG00000012020 I 0.914
ENSMICG00000011448 Microcebus murinus ENSMICG00000011448 I 0.914
ENSMMUG00000004499 Macaca mulatta ENSMMUG00000004499 I 0.914
ENSNLEG00000015257 Nomascus leucogenys ENSNLEG00000015257 I 0.914
ENSOARG00000016775 Ovis aries ENSOARG00000016775 I 0.914
ATF4 Otolemur garnettii ENSOGAG00000033566 I 0.914
ENSPANG00000025194 Papio anubis ENSPANG00000025194 I 0.914
ATF4 Procavia capensis ENSPCAG00000004089 I 0.914
ENSPPYG00000011842 Pongo abelii ENSPPYG00000011842 I 0.914
ATF4 Pan troglodytes ENSPTRG00000014398 I 0.914
ATF4 Pteropus vampyrus ENSPVAG00000015476 I 0.914
Atf4 Rattus norvegicus ENSRNOG00000017801 I 0.914
ATF4 Sus scrofa ENSSSCG00000000084 I 0.914
ENSSTOG00000025355 Ictidomys tridecemlineatus ENSSTOG00000025355 I 0.914
ATF4 Tupaia belangeri ENSTBEG00000005052 I 0.914
ATF4 Tursiops truncatus ENSTTRG00000014581 I 0.914
ENSBTAP00000023213-D1 Bos grunniens ENSBTAP00000023213-D1 I 0.914
ENSP00000384587 Macaca fascicularis ENSP00000384587 I 0.914
ENSMPUG00000009865 Mustela putorius furo ENSMPUG00000009865 I 0.913
ENSMPUG00000013386 Mustela putorius furo ENSMPUG00000013386 I 0.913
ENSAPLG00000001773 Anas platyrhynchos ENSAPLG00000001773 I 0.910
ENSFALG00000012313 Ficedula albicollis ENSFALG00000012313 I 0.910
ATF4 Gallus gallus ENSGALG00000012135 I 0.910
ATF4 Taeniopygia guttata ENSTGUG00000010225 I 0.910
Aan_R011605 Calypte anna Aan_R011605 I 0.910
Brh_R011254 Buceros rhinoceros Brh_R011254 I 0.910
Gfo_R004722 Geospiza fortis Gfo_R004722 I 0.910
Tal_R009484 Tyto alba Tal_R009484 I 0.910
ATF4 Monodelphis domestica ENSMODG00000009380 I 0.908
ENSPSIG00000011085 Pelodiscus sinensis ENSPSIG00000011085 I 0.908
ENSSHAG00000014069 Sarcophilus harrisii ENSSHAG00000014069 I 0.908
Ogr14426 Ophisaurus gracilis Ogr14426 I 0.908
ATF4 Ornithorhynchus anatinus ENSOANG00000011026 I 0.904
Cmyd_10007892 Chelonia mydas Cmyd_10007892 I 0.904
ENSMLUG00000027798 Myotis lucifugus ENSMLUG00000027798 I 0.903
Myotis_brandtii_ATF4_10014009 Myotis brandtii Myotis_brandtii_ATF4_10014009 I 0.903
ENSMEUG00000011209 Macropus eugenii ENSMEUG00000011209 I 0.902
Afo_R007931 Aptenodytes forsteri Afo_R007931 I 0.899
ENSLACG00000003943 Latimeria chalumnae ENSLACG00000003943 I 0.895
Alligator_sinensis_CCG008004.1 Alligator sinensis Alligator_sinensis_CCG008004.1 I 0.895
Pvit_04694 Pogona vitticeps Pvit_04694 I 0.895
ATF4 Ochotona princeps ENSOPRG00000010583 I 0.887
ENSLOCG00000011103 Lepisosteus oculatus ENSLOCG00000011103 I 0.881
ATF4 Meleagris gallopavo ENSMGAG00000012387 I 0.881
ENSGGOG00000024022 Gorilla gorilla ENSGGOG00000024022 I 0.876
ENSGMOG00000018039 Gadus morhua ENSGMOG00000018039 I 0.876
atf4.L Xenopus laevis XB-GENE-983847 I 0.876
atf4 Xenopus tropicalis XB-GENE-983841 I 0.872
ATF4 Anolis carolinensis ENSACAG00000007573 I 0.870
ENSPFOG00000005452 Poecilia formosa ENSPFOG00000005452 I 0.867
ENSXMAG00000002653 Xiphophorus maculatus ENSXMAG00000002653 I 0.867
ENSAMXG00000011467 Astyanax mexicanus ENSAMXG00000011467 I 0.861
atf4b Danio rerio ENSDARG00000038141 I 0.859
ENSONIG00000008552 Oreochromis niloticus ENSONIG00000008552 I 0.853
ENSGMOG00000014904 Gadus morhua ENSGMOG00000014904 I 0.851
atf4a Gasterosteus aculeatus ENSGACG00000019842 I 0.849
ATF4 Oryzias latipes ENSORLG00000013424 I 0.849
ENSPFOG00000006088 Poecilia formosa ENSPFOG00000006088 I 0.848
atf4a Tetraodon nigroviridis ENSTNIG00000000373 I 0.848
atf4a Takifugu rubripes ENSTRUG00000001898 I 0.848
ENSXMAG00000008039 Xiphophorus maculatus ENSXMAG00000008039 I 0.848
atf4a Danio rerio ENSDARG00000039515 I 0.847
ENSONIG00000013091 Oreochromis niloticus ENSONIG00000013091 I 0.846
atf4.S Xenopus laevis XB-GENE-6251859 I 0.846
atf4a Oryzias latipes ENSORLG00000010649 I 0.837
ENSSTOG00000024459 Ictidomys tridecemlineatus ENSSTOG00000024459 I 0.818
ENSSTOG00000025644 Ictidomys tridecemlineatus ENSSTOG00000025644 I 0.802