RBAK (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000146587 T094959_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
RBAK
M07595_2.00		 Homo sapiens
BSYYBYTYSTYHCBN
NVGDRASRARVRRSV		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
RBAK.RCADE.ReprocessedData		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000275423 C2H2 ZF 261 283
ENSP00000275423 C2H2 ZF 289 311
ENSP00000275423 C2H2 ZF 317 339
ENSP00000275423 C2H2 ZF 345 367
ENSP00000275423 C2H2 ZF 373 395
ENSP00000275423 C2H2 ZF 401 423
ENSP00000275423 C2H2 ZF 429 451
ENSP00000275423 C2H2 ZF 457 479
ENSP00000275423 C2H2 ZF 511 530
ENSP00000275423 C2H2 ZF 539 561
ENSP00000275423 C2H2 ZF 567 589
ENSP00000275423 C2H2 ZF 595 617
ENSP00000275423 C2H2 ZF 623 645
ENSP00000275423 C2H2 ZF 651 673
ENSP00000275423 C2H2 ZF 679 701
ENSP00000380120 C2H2 ZF 261 283
ENSP00000380120 C2H2 ZF 289 311
ENSP00000380120 C2H2 ZF 317 339
ENSP00000380120 C2H2 ZF 345 367
ENSP00000380120 C2H2 ZF 373 395
ENSP00000380120 C2H2 ZF 401 423
ENSP00000380120 C2H2 ZF 429 451
ENSP00000380120 C2H2 ZF 457 479
ENSP00000380120 C2H2 ZF 511 530
ENSP00000380120 C2H2 ZF 539 561
ENSP00000380120 C2H2 ZF 567 589
ENSP00000380120 C2H2 ZF 595 617
ENSP00000380120 C2H2 ZF 623 645
ENSP00000380120 C2H2 ZF 651 673
ENSP00000380120 C2H2 ZF 679 701

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

22 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSNLEG00000015490 Nomascus leucogenys ENSNLEG00000015490 I 0.827
RBAK Gorilla gorilla ENSGGOG00000008465 I 0.827
ENSPANG00000015671 Papio anubis ENSPANG00000015671 I 0.827
RBAK Pan troglodytes ENSPTRG00000018880 I 0.827
ENSP00000275423 Macaca fascicularis ENSP00000275423 I 0.827
ENSMMUG00000006521 Macaca mulatta ENSMMUG00000006521 I 0.827
ENSCSAG00000017653 Chlorocebus sabaeus ENSCSAG00000017653 I 0.827
ENSPPYG00000017329 Pongo abelii ENSPPYG00000017329 I 0.825
RBAK Callithrix jacchus ENSCJAG00000021500 I 0.824
ENSOARG00000002641 Ovis aries ENSOARG00000002641 I 0.810
RBAK Myotis lucifugus ENSMLUG00000004409 I 0.808
RBAK Bos taurus ENSBTAG00000010291 I 0.807
ENSMPUG00000016607 Mustela putorius furo ENSMPUG00000016607 I 0.806
RBAK Procavia capensis ENSPCAG00000015859 I 0.796
RBAK Equus caballus ENSECAG00000009724 I 0.796
RBAK Canis familiaris ENSCAFG00000029211 I 0.792
RBAK Sus scrofa ENSSSCG00000008668 I 0.773
Rbak Mus musculus ENSMUSG00000061898 I 0.770
Rbak Rattus norvegicus ENSRNOG00000001099 I 0.768
RBAK Loxodonta africana ENSLAFG00000008833 I 0.762
RBAK Erinaceus europaeus ENSEEUG00000007766 I 0.757