ZIK1 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000171649 T095108_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZIK1
M07633_2.00		 Homo sapiens
VNNWYBYNKTGCYWTTGYYHY
RDRRCAAWRGCAMNRVRWNNB		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZIK1.RCADE.ReprocessedData		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000438487 C2H2 ZF 226 248
ENSP00000438487 C2H2 ZF 254 276
ENSP00000438487 C2H2 ZF 282 304
ENSP00000438487 C2H2 ZF 310 332
ENSP00000438487 C2H2 ZF 338 360
ENSP00000438487 C2H2 ZF 366 388
ENSP00000438487 C2H2 ZF 394 416
ENSP00000438487 C2H2 ZF 422 444
ENSP00000438487 C2H2 ZF 450 472
ENSP00000468937 C2H2 ZF 184 206
ENSP00000468937 C2H2 ZF 212 234
ENSP00000468937 C2H2 ZF 240 262
ENSP00000468937 C2H2 ZF 268 290
ENSP00000468937 C2H2 ZF 296 318
ENSP00000468937 C2H2 ZF 324 346
ENSP00000468937 C2H2 ZF 352 374
ENSP00000468937 C2H2 ZF 380 402
ENSP00000468937 C2H2 ZF 408 430
ENSP00000472867 C2H2 ZF 239 261
ENSP00000472867 C2H2 ZF 267 289
ENSP00000472867 C2H2 ZF 295 317
ENSP00000472867 C2H2 ZF 323 345
ENSP00000472867 C2H2 ZF 351 373
ENSP00000472867 C2H2 ZF 379 401
ENSP00000472867 C2H2 ZF 407 429
ENSP00000472867 C2H2 ZF 435 457
ENSP00000472867 C2H2 ZF 463 485

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

13 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZIK1 Pan troglodytes ENSPTRG00000011562 I 0.826
ENSCSAG00000001627 Chlorocebus sabaeus ENSCSAG00000001627 I 0.824
ENSMICG00000007450 Microcebus murinus ENSMICG00000007450 I 0.824
ENSPANG00000000290 Papio anubis ENSPANG00000000290 I 0.822
ENSCJAG00000000037 Callithrix jacchus ENSCJAG00000000037 I 0.822
ZIK1 Macaca mulatta ENSMMUG00000009292 I 0.822
ENSTSYG00000008565 Tarsius syrichta ENSTSYG00000008565 I 0.822
ENSP00000303820 Macaca fascicularis ENSP00000303820 I 0.822
ZIK1 Oryctolagus cuniculus ENSOCUG00000029400 I 0.808
Zik1 Mus musculus ENSMUSG00000030393 I 0.808
LOC100911224 Rattus norvegicus ENSRNOG00000046455 I 0.807
Zik1 Rattus norvegicus ENSRNOG00000055843 I 0.807