Zfp740 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000046897 T101215_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; limb; and sensory organ. Orthologous to human ZNF740 (zinc finger protein 740). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Zfp740
M00143_2.00		 Mus musculus
HMCCCCCNNN
NNNGGGGGKD		 PBM
Badis et al.(2009)
Zfp740_0925		 (Direct) (Direct)
Zfp740
M00784_2.00		 Mus musculus
MCCCCCCNHN
NDNGGGGGGK		 PBM
Weirauch et al.(2013)
pTH2857		 (Direct) (Direct)
Zfp740
M02935_2.00		 Mus musculus
NCCCCCCCAH
DTGGGGGGGN		 SELEX
Jolma et al.(2013)
Zfp740_1		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF740
M02891_2.00 		Homo sapiens
VCCCCCCCMY
RKGGGGGGGB		 SELEX
Jolma et al.(2013)
ZNF740_1 		0.807 0.956
ZNF740
M02892_2.00 		Homo sapiens
VCCCCCCCAY
RTGGGGGGGB		 SELEX
Jolma et al.(2013)
ZNF740_2 		0.807 0.956
ZNF740
M04467_2.00 		Homo sapiens
NYVCCCCCCCCAC
GTGGGGGGGGBRN		 SELEX
Yin et al.(2017)
ZNF740_eDBD_HT-SELEX 		0.807 0.956
ZNF740
M04469_2.00 		Homo sapiens
NYNCCCCCCCCAC
GTGGGGGGGGNRN		 SELEX
Yin et al.(2017)
ZNF740_FL_HT-SELEX 		0.807 0.956
ZNF740
M10221_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ZNF740_02 		0.807 0.956
ZNF740
M04468_2.00 		Homo sapiens
YYDCCCCCCCCAY
RTGGGGGGGGHRR		 SELEX
Yin et al.(2017)
ZNF740_eDBD_Methyl-HT-SELEX 		0.807 0.956
ZNF740
M04470_2.00 		Homo sapiens
NYVCCCCCCCCAC
GTGGGGGGGGBRN		 SELEX
Yin et al.(2017)
ZNF740_FL_Methyl-HT-SELEX 		0.807 0.956
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00143_2.00 C2H2 ZF 16 38
M00143_2.00 C2H2 ZF 44 66
M00143_2.00 C2H2 ZF 72 93
M00784_2.00 C2H2 ZF 16 38
M00784_2.00 C2H2 ZF 44 66
M00784_2.00 C2H2 ZF 72 93

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000112985 C2H2 ZF 76 98
ENSMUSP00000112985 C2H2 ZF 104 126
ENSMUSP00000112985 C2H2 ZF 132 153
ENSMUSP00000113770 C2H2 ZF 88 110
ENSMUSP00000113770 C2H2 ZF 116 138
ENSMUSP00000113770 C2H2 ZF 144 165

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

51 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZNF740 Anolis carolinensis ENSACAG00000006993 I 0.827
ZNF740 Echinops telfairi ENSETEG00000006127 I 0.827
ENSPSIG00000003019 Pelodiscus sinensis ENSPSIG00000003019 I 0.827
Znf740 Rattus norvegicus ENSRNOG00000012192 I 0.827
Alligator_sinensis_CCG005405.1 Alligator sinensis Alligator_sinensis_CCG005405.1 I 0.827
ENSDORG00000002972 Dipodomys ordii ENSDORG00000002972 I 0.827
ENSMEUG00000003745 Macropus eugenii ENSMEUG00000003745 I 0.823
ZNF740 Felis catus ENSFCAG00000005868 I 0.823
ENSAMEG00000012221 Ailuropoda melanoleuca ENSAMEG00000012221 I 0.823
ENSGALG00000026752 Gallus gallus ENSGALG00000026752 I 0.823
ZNF740 Canis familiaris ENSCAFG00000007070 I 0.823
ZNF740 Tupaia belangeri ENSTBEG00000015437 I 0.823
ENSSHAG00000000623 Sarcophilus harrisii ENSSHAG00000000623 I 0.823
ENSCPOG00000014815 Cavia porcellus ENSCPOG00000014815 I 0.823
ZNF740 Dasypus novemcinctus ENSDNOG00000033888 I 0.823
ENSSTOG00000011188 Ictidomys tridecemlineatus ENSSTOG00000011188 I 0.823
Cmyd_10004697 Chelonia mydas Cmyd_10004697 I 0.823
ZNF740 Loxodonta africana ENSLAFG00000009191 I 0.820
ENSFALG00000004356 Ficedula albicollis ENSFALG00000004356 I 0.820
Gfo_R004393 Geospiza fortis Gfo_R004393 I 0.820
ZNF740 Myotis lucifugus ENSMLUG00000017275 I 0.811
Myotis_brandtii_ZNF740_10023006 Myotis brandtii Myotis_brandtii_ZNF740_10023006 I 0.811
ZNF740 Oryctolagus cuniculus ENSOCUG00000001422 I 0.811
ZNF740 Sorex araneus ENSSARG00000012946 I 0.807
ENSSSCG00000000256 Sus scrofa ENSSSCG00000000256 I 0.807
ENSBTAP00000048192-D3 Bos grunniens ENSBTAP00000048192-D3 I 0.807
ENSBTAP00000021935-D1 Bos grunniens ENSBTAP00000021935-D1 I 0.807
ZNF740 Tursiops truncatus ENSTTRG00000002776 I 0.807
ENSTSYG00000010942 Tarsius syrichta ENSTSYG00000010942 I 0.807
ZNF740 Pan troglodytes ENSPTRG00000005005 I 0.807
ENSMMUP00000006945 Macaca fascicularis ENSMMUP00000006945 I 0.807
ZNF740 Otolemur garnettii ENSOGAG00000025330 I 0.807
ZNF740 Macaca mulatta ENSMMUG00000005246 I 0.807
ZNF740 Callithrix jacchus ENSCJAG00000018381 I 0.807
ZNF740 Gorilla gorilla ENSGGOG00000006790 I 0.807
ZNF740 Homo sapiens ENSG00000139651 D 0.807
ENSBTAG00000046481 Bos taurus ENSBTAG00000046481 I 0.807
ENSNLEG00000017717 Nomascus leucogenys ENSNLEG00000017717 I 0.807
ENSPPYG00000004570 Pongo abelii ENSPPYG00000004570 I 0.807
ZNF740 Equus caballus ENSECAG00000013071 I 0.807
ENSPANG00000018242 Papio anubis ENSPANG00000018242 I 0.807
znf740 Xenopus tropicalis XB-GENE-1219010 I 0.803
znf740.S Xenopus laevis XB-GENE-1219015 I 0.803
ENSBTAG00000016502 Bos taurus ENSBTAG00000016502 I 0.801
ZNF740 Microcebus murinus ENSMICG00000014191 I 0.791
ENSCSAG00000005533 Chlorocebus sabaeus ENSCSAG00000005533 I 0.785
ENSAMXG00000004859 Astyanax mexicanus ENSAMXG00000004859 I 0.775
znf740b Danio rerio ENSDARG00000061174 I 0.771
ENSLOCG00000006558 Lepisosteus oculatus ENSLOCG00000006558 I 0.758
ENSPFOG00000001757 Poecilia formosa ENSPFOG00000001757 I 0.758