Zfp354a (Rattus norvegicus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSRNOG00000003634 T108883_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; nucleolar fragmentation; and response to folic acid. Located in nucleolus. Orthologous to human ZNF354A (zinc finger protein 354A). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF354A
M08331_2.00 		Homo sapiens
RTTTARDCCATTTAY
RTAAATGGHYTAAAY		 ChIP-seq
Schmitges et al.(2016)
O60765_5-9.RCADE 		0.813 0.967
ZNF354A
M07622_2.00 		Homo sapiens
RTTTARHCCATTTAC
GTAAATGGDYTAAAY		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF354A.RCADE.OriginalMapping 		0.813 0.967
ZNF354A
M08914_2.00 		Homo sapiens
DTTYHDNYCHTTTMYWTTTADTGW
WCAHTAAAWRKAAADGRNHDRAAH		 Misc
Kulakovskiy et al.(2013)
Z354A_HUMAN.H11MO.0.C 		0.813 0.967
ZNF354B
M07653_2.00 		Homo sapiens
RDWTAKYYCMTT
AAKGRRMTAWHY		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF354B.RCADE.ReprocessedData 		0.767 0.916
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000049437 C2H2 ZF 188 210
ENSRNOP00000049437 C2H2 ZF 216 238
ENSRNOP00000049437 C2H2 ZF 244 266
ENSRNOP00000049437 C2H2 ZF 272 294
ENSRNOP00000049437 C2H2 ZF 325 347
ENSRNOP00000049437 C2H2 ZF 353 375
ENSRNOP00000049437 C2H2 ZF 381 403
ENSRNOP00000049437 C2H2 ZF 409 431
ENSRNOP00000049437 C2H2 ZF 437 459
ENSRNOP00000049437 C2H2 ZF 465 487
ENSRNOP00000049437 C2H2 ZF 493 515
ENSRNOP00000049437 C2H2 ZF 521 543
ENSRNOP00000049437 C2H2 ZF 549 571
ENSRNOP00000070798 C2H2 ZF 142 164
ENSRNOP00000070798 C2H2 ZF 170 192
ENSRNOP00000070798 C2H2 ZF 198 220
ENSRNOP00000070798 C2H2 ZF 226 248
ENSRNOP00000070798 C2H2 ZF 279 301
ENSRNOP00000070798 C2H2 ZF 307 329
ENSRNOP00000070798 C2H2 ZF 335 357
ENSRNOP00000070798 C2H2 ZF 363 385
ENSRNOP00000070798 C2H2 ZF 391 413
ENSRNOP00000070798 C2H2 ZF 419 441
ENSRNOP00000070798 C2H2 ZF 447 469
ENSRNOP00000070798 C2H2 ZF 475 497
ENSRNOP00000070798 C2H2 ZF 503 525

Links

Other C2H2 ZF family TFs
Other Rattus norvegicus TFs

49 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZNF354A Felis catus ENSFCAG00000023911 I 0.817
ZNF354A Myotis lucifugus ENSMLUG00000013294 I 0.816
ZNF354A Canis familiaris ENSCAFG00000031000 I 0.816
ENSMPUG00000000732 Mustela putorius furo ENSMPUG00000000732 I 0.816
Myotis_brandtii_ZNF354A_10002378 Myotis brandtii Myotis_brandtii_ZNF354A_10002378 I 0.816
ZNF354A Pteropus vampyrus ENSPVAG00000016750 I 0.815
Zfp354a Mus musculus ENSMUSG00000020364 I 0.815
ENSEEUG00000008362 Erinaceus europaeus ENSEEUG00000008362 I 0.814
ENSMMUG00000008975 Macaca mulatta ENSMMUG00000008975 I 0.814
ZNF354A Callithrix jacchus ENSCJAG00000012077 I 0.814
ENSDNOG00000043806 Dasypus novemcinctus ENSDNOG00000043806 I 0.813
ZNF354A Oryctolagus cuniculus ENSOCUG00000029378 I 0.813
ENSPANG00000013855 Papio anubis ENSPANG00000013855 I 0.813
ZNF354A Homo sapiens ENSG00000169131 D 0.813
ZNF354A Tursiops truncatus ENSTTRG00000010631 I 0.813
ENSNLEG00000001410 Nomascus leucogenys ENSNLEG00000001410 I 0.813
ZNF354A Microcebus murinus ENSMICG00000006390 I 0.812
ZNF354A Pan troglodytes ENSPTRG00000017606 I 0.812
ZNF354A Bos taurus ENSBTAG00000006428 I 0.812
ZNF354A Gorilla gorilla ENSGGOG00000002534 I 0.812
ENSP00000300870-D85 Bos grunniens ENSP00000300870-D85 I 0.812
ZNF354A Otolemur garnettii ENSOGAG00000024624 I 0.812
ENSPPYG00000016111 Pongo abelii ENSPPYG00000016111 I 0.811
ENSCSAG00000008589 Chlorocebus sabaeus ENSCSAG00000008589 I 0.810
ZNF354A Equus caballus ENSECAG00000012431 I 0.810
ENSSTOG00000024118 Ictidomys tridecemlineatus ENSSTOG00000024118 I 0.810
Zfp354a Dipodomys ordii ENSDORG00000009396 I 0.808
ZNF354A Loxodonta africana ENSLAFG00000002909 I 0.805
ZNF354A Ochotona princeps ENSOPRG00000017155 I 0.790
ENSOARG00000006794 Ovis aries ENSOARG00000006794 I 0.784
ZNF354B Callithrix jacchus ENSCJAG00000018848 I 0.771
ZNF354B Homo sapiens ENSG00000178338 D 0.767
ZNF354B Gorilla gorilla ENSGGOG00000000628 I 0.767
ZNF354B Pan troglodytes ENSPTRG00000017609 I 0.767
ENSPPYG00000016113 Pongo abelii ENSPPYG00000016113 I 0.766
ZNF354B Dasypus novemcinctus ENSDNOG00000031129 I 0.763
ENSCSAG00000008583 Chlorocebus sabaeus ENSCSAG00000008583 I 0.763
ENSOCUG00000029238 Oryctolagus cuniculus ENSOCUG00000029238 I 0.762
ENSNLEG00000001411 Nomascus leucogenys ENSNLEG00000001411 I 0.762
ZNF354B Felis catus ENSFCAG00000022066 I 0.762
ENSMPUG00000000728 Mustela putorius furo ENSMPUG00000000728 I 0.761
ENSAMEG00000009090 Ailuropoda melanoleuca ENSAMEG00000009090 I 0.761
ZNF354B Cavia porcellus ENSCPOG00000002227 I 0.761
ZNF354B Canis familiaris ENSCAFG00000029114 I 0.761
ENSP00000327143 Macaca fascicularis ENSP00000327143 I 0.760
ZNF354B Macaca mulatta ENSMMUG00000008976 I 0.760
ZNF354B Equus caballus ENSECAG00000012028 I 0.759
ENSPANG00000013252 Papio anubis ENSPANG00000013252 I 0.759