dmd-10 (Caenorhabditis elegans)
DM

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00751 (DM) IPR001275 WBGene00007929 T169434_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in mechanosensory behavior and response to osmotic stress. Predicted to be active in nucleus. Is expressed in several structures, including AVG; body wall musculature; head neurons; intestine; and vulval muscle. Orthologous to several human genes including DMRTB1 (DMRT like family B with proline rich C-terminal 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
dmd-10
M00657_2.00		 Caenorhabditis elegans
AWTGTTTC
GAAACAWT		 PBM
Narasimhan et al.(2015)
pTH9142		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CBG09413
M01924_2.00 		Caenorhabditis briggsae
AATGTTTC
GAAACATT		 PBM
Weirauch et al.(2014)
pTH8330 		0.966 0.979
CBN06605
M01925_2.00 		Caenorhabditis brenneri
NWGTWKN
NMWACWN		 PBM
Weirauch et al.(2014)
pTH9247 		0.963 0.957
CJA05633_CONSTRUCT
M01936_2.00 		PBM CONSTRUCTS
NWGTWDN
NHWACWN		 PBM
Weirauch et al.(2014)
pTH9344 		0.963 0.936
WUBG_11979
M01922_2.00 		Wuchereria bancrofti
ATGTWTCA
TGAWACAT		 PBM
Weirauch et al.(2014)
pTH9296 		0.956 0.872
Bm2567
M01923_2.00 		Brugia malayi
NNNWGTTKHN
NDMAACWNNN		 PBM
Weirauch et al.(2014)
pTH9246 		0.956 0.872
dmd-3
M00658_2.00 		Caenorhabditis elegans
NNWGTWDN
NHWACWNN		 PBM
Narasimhan et al.(2015)
pTH10638 		0.914 0.745
For this family, TFs with SR scores > 0.845 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00657_2.00 DM 36 82

DNA Binding Domains

Protein ID Domain From To Sequence
C34D1.1 DM 36 82

Links

Other DM family TFs
Other Caenorhabditis elegans TFs

47 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBG09413 Caenorhabditis briggsae CBG09413 D 0.966
L893_g31098 Steinernema glaseri L893_g31098 I 0.965
L889_g10733 Steinernema feltiae L889_g10733 I 0.964
L596_g998 Steinernema carpocapsae L596_g998 I 0.964
L892_g22881 Steinernema scapterisci L892_g22881 I 0.964
L898_g33808 Steinernema monticolum L898_g33808 I 0.964
CJA05633_CONSTRUCT PBM CONSTRUCTS CJA05633_CONSTRUCT D 0.963
CBN06605 Caenorhabditis brenneri CBN06605 D 0.963
CRE31027 Caenorhabditis remanei CRE31027 I 0.963
DME_0001004201 Dracunculus medinensis DME_0001004201 I 0.958
BXY_0200700 Bursaphelenchus xylophilus BXY_0200700 I 0.958
Hba_18605 Heterorhabditis bacteriophora Hba_18605 I 0.958
WUBG_11979 Wuchereria bancrofti WUBG_11979 D 0.956
EVEC_0001123001 Enterobius vermicularis EVEC_0001123001 I 0.956
EEL_0000689901 Elaeophora elaphi EEL_0000689901 I 0.956
nLs.2.1.2.g05589 Litomosoides sigmodontis nLs.2.1.2.g05589 I 0.956
LOAG_11460 Loa loa LOAG_11460 I 0.956
nAv.1.0.1.g09212 Acanthocheilonema viteae nAv.1.0.1.g09212 I 0.956
nDi.2.2.2.g08811 Dirofilaria immitis nDi.2.2.2.g08811 I 0.956
Bm2567 Brugia malayi Bm2567 D 0.956
WBGene00242643 Onchocerca volvulus WBGene00242643 I 0.956
ASIM_0001608201 Anisakis simplex ASIM_0001608201 I 0.956
TCLT_0000243901 Thelazia callipaeda TCLT_0000243901 I 0.956
nOo.2.0.1.g05035 Onchocerca ochengi nOo.2.0.1.g05035 I 0.956
BTMF_0001653601 Brugia timori BTMF_0001653601 I 0.956
NBR_0000774001 Nippostrongylus brasiliensis NBR_0000774001 I 0.955
PTRK_0001597400 Parastrongyloides trichosuri PTRK_0001597400 I 0.938
SVE_0753200 Strongyloides venezuelensis SVE_0753200 I 0.938
SPAL_0001233100 Strongyloides papillosus SPAL_0001233100 I 0.938
L898_g30067 Steinernema monticolum L898_g30067 I 0.919
L892_g27879 Steinernema scapterisci L892_g27879 I 0.919
ASIM_0000241101 Anisakis simplex ASIM_0000241101 I 0.918
ASIM_0000264301 Anisakis simplex ASIM_0000264301 I 0.918
ANCDUO_19569 Ancylostoma duodenale ANCDUO_19569 I 0.914
ANCCAN_13991 Ancylostoma caninum ANCCAN_13991 I 0.914
TELCIR_05158 Teladorsagia circumcincta TELCIR_05158 I 0.914
dmd-3 Caenorhabditis elegans WBGene00012832 D 0.914
CJA05020 Caenorhabditis japonica CJA05020 I 0.914
CJA37832 Caenorhabditis japonica CJA37832 I 0.914
NECAME_07661 Necator americanus NECAME_07661 I 0.914
nDi.2.2.2.g10419 Dirofilaria immitis nDi.2.2.2.g10419 I 0.912
BTMF_0001659501 Brugia timori BTMF_0001659501 I 0.912
nOo.2.0.1.g12565 Onchocerca ochengi nOo.2.0.1.g12565 I 0.912
nAv.1.0.1.g01085 Acanthocheilonema viteae nAv.1.0.1.g01085 I 0.912
OESDEN_09202 Oesophagostomum dentatum OESDEN_09202 I 0.906
BXY_0352300 Bursaphelenchus xylophilus BXY_0352300 I 0.882
SVE_1703300 Strongyloides venezuelensis SVE_1703300 I 0.877