ARGFX (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000186103 T209932_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the ARGFX homeobox gene family. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ARGFX
M05369_2.00		 Homo sapiens
NYTAATTARH
DYTAATTARN		 SELEX
Yin et al.(2017)
ARGFX_eDBD_HT-SELEX_1		 (Direct) (Direct)
ARGFX
M05370_2.00		 Homo sapiens
HTAATYTAATTAR
YTAATTARATTAD		 SELEX
Yin et al.(2017)
ARGFX_eDBD_HT-SELEX_2		 (Direct) (Direct)
ARGFX
M05371_2.00		 Homo sapiens
NYTAATTAGH
DCTAATTARN		 SELEX
Yin et al.(2017)
ARGFX_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
ARGFX
M05372_2.00		 Homo sapiens
HTAATYTAATTAR
YTAATTARATTAD		 SELEX
Yin et al.(2017)
ARGFX_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000335578 Homeodomain 79 135

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

30 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ARGFX Pan troglodytes ENSPTRG00000015277 I 0.867
ENSPPYG00000013497 Pongo abelii ENSPPYG00000013497 I 0.834
ENSNLEG00000013255 Nomascus leucogenys ENSNLEG00000013255 I 0.820
ARGFX Gorilla gorilla ENSGGOG00000005362 I 0.818
ENSMMUP00000021529 Macaca fascicularis ENSMMUP00000021529 I 0.816
ARGFX Macaca mulatta ENSMMUG00000016395 I 0.816
ENSPANG00000009686 Papio anubis ENSPANG00000009686 I 0.798
ENSPPYG00000008158 Pongo abelii ENSPPYG00000008158 I 0.794
ARGFX Callithrix jacchus ENSCJAG00000008507 I 0.766
ARGFX Otolemur garnettii ENSOGAG00000002406 I 0.761
ARGFX Tupaia belangeri ENSTBEG00000015401 I 0.749
ENSSSCG00000011886 Sus scrofa ENSSSCG00000011886 I 0.740
ARGFX Bos taurus ENSBTAG00000002273 I 0.739
ENSP00000335578-D1 Bos grunniens ENSP00000335578-D1 I 0.739
ENSOARG00000020026 Ovis aries ENSOARG00000020026 I 0.739
ENSCPOG00000006393 Cavia porcellus ENSCPOG00000006393 I 0.707
ARGFX Oryctolagus cuniculus ENSOCUG00000008795 I 0.694
ARGFX Tursiops truncatus ENSTTRG00000001349 I 0.675
ARGFX Dasypus novemcinctus ENSDNOG00000031231 I 0.664
ENSOPRG00000012148 Ochotona princeps ENSOPRG00000012148 I 0.631
ARGFX Equus caballus ENSECAG00000013996 I 0.626
PXEA_0000230101 Protopolystoma xenopodis PXEA_0000230101 I 0.617
SROB_0002221601 Schistosoma rodhaini SROB_0002221601 I 0.605
TELCIR_21719 Teladorsagia circumcincta TELCIR_21719 I 0.605
TRE_0001559401 Trichobilharzia regenti TRE_0001559401 I 0.605
SMTD_0002261301 Schistosoma mattheei SMTD_0002261301 I 0.605
Smp_171380 Schistosoma mansoni Smp_171380 I 0.605
CGOC_0000645001 Cylicostephanus goldi CGOC_0000645001 I 0.605
EEL_0000436201 Elaeophora elaphi EEL_0000436201 I 0.605
MhA1_Contig726.frz3.gene2 Meloidogyne hapla MhA1_Contig726.frz3.gene2 I 0.600