HMEL015659 (Heliconius melpomene)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 HMEL015659 T219615_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Otx1
M00396_2.00 		Mus musculus
NTAAKCYN
NRGMTTAN		 PBM
Berger et al.(2008)
Otx1_2325 		0.462 1.000
Otx2
M00418_2.00 		Mus musculus
NTAAKMBN
NVKMTTAN		 PBM
Berger et al.(2008)
Otx2_3441 		0.462 1.000
OTX1
M03116_2.00 		Homo sapiens
NNTAAKCGGATTANN
NNTAATCCGMTTANN		 SELEX
Jolma et al.(2013)
OTX1_1 		0.462 1.000
OTX1
M03117_2.00 		Homo sapiens
NTAATCSB
VSGATTAN		 SELEX
Jolma et al.(2013)
OTX1_2 		0.462 1.000
OTX2
M03197_2.00 		Homo sapiens
NHTAAKCGGATTANN
NNTAATCCGMTTADN		 SELEX
Jolma et al.(2013)
OTX2_1 		0.462 1.000
OTX2
M03198_2.00 		Homo sapiens
HTAATCCB
VGGATTAD		 SELEX
Jolma et al.(2013)
OTX2_2 		0.462 1.000
Otx1
M03249_2.00 		Mus musculus
NNTAAKCGGATTANN
NNTAATCCGMTTANN		 SELEX
Jolma et al.(2013)
Otx1_1 		0.462 1.000
Otx1
M03250_2.00 		Mus musculus
NTAATCCN
NGGATTAN		 SELEX
Jolma et al.(2013)
Otx1_2 		0.462 1.000
oc
M03808_2.00 		Drosophila melanogaster
HTAATCCB
VGGATTAD		 SELEX
Nitta et al.(2015)
oc_1 		0.462 1.000
OTX1
M05022_2.00 		Homo sapiens
NTAATCCN
NGGATTAN		 SELEX
Yin et al.(2017)
OTX1_eDBD_HT-SELEX 		0.462 1.000
OTX1
M05024_2.00 		Homo sapiens
NTAATCCNNN
NNNGGATTAN		 SELEX
Yin et al.(2017)
OTX1_FL_HT-SELEX 		0.462 1.000
OTX2
M05251_2.00 		Homo sapiens
NTAATCCN
NGGATTAN		 SELEX
Yin et al.(2017)
OTX2_FL_HT-SELEX 		0.462 1.000
oc
M06502_2.00 		Drosophila melanogaster
TAATCC
GGATTA		 B1H
Mathelier et al.(2014)
MA0234.1 		0.462 1.000
oc
M06282_2.00 		Drosophila melanogaster
WTAATCC
GGATTAW		 B1H
Zhu et al.(2011)
Oc_Cell_FBgn0004102 		0.462 1.000
oc
M06283_2.00 		Drosophila melanogaster
NTAATCCB
VGGATTAN		 B1H
Zhu et al.(2011)
Oc_SOLEXA_FBgn0004102 		0.462 1.000
OTX2
M09153_2.00 		Homo sapiens
BYTAATCCYYN
NRRGGATTARV		 Misc
Kulakovskiy et al.(2013)
OTX2_HUMAN.H11MO.0.A 		0.462 1.000
Otx2
M09183_2.00 		Mus musculus
HTAATCCYNYNN
NNRNRGGATTAD		 Misc
Kulakovskiy et al.(2013)
OTX2_MOUSE.H11MO.0.A 		0.462 1.000
Otx2
M09569_2.00 		Mus musculus
NHTAATCCHB
VDGGATTADN		 Misc
Heinz et al.(2010)
EpiLC-Otx2_GSE56098 		0.462 1.000
oc
M09681_2.00 		Drosophila melanogaster
HTAATCCN
NGGATTAD		 Misc
Kulakovskiy et al.(2009)
oc 		0.462 1.000
OTX1
M10673_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OTX1_Q5 		0.462 1.000
OTX2
M10727_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OTX2_Q3_01 		0.462 1.000
OTX2
M10728_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OTX2_Q3 		0.462 1.000
OTX1
M05023_2.00 		Homo sapiens
NTAATCCN
NGGATTAN		 SELEX
Yin et al.(2017)
OTX1_eDBD_Methyl-HT-SELEX 		0.462 1.000
OTX1
M05025_2.00 		Homo sapiens
HTAATCCNHN
NDNGGATTAD		 SELEX
Yin et al.(2017)
OTX1_FL_Methyl-HT-SELEX 		0.462 1.000
OTX2
M05252_2.00 		Homo sapiens
NTAATCCN
NGGATTAN		 SELEX
Yin et al.(2017)
OTX2_FL_Methyl-HT-SELEX 		0.462 1.000
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HMEL015659-PA Homeodomain 1 29

Links

Other Homeodomain family TFs
Other Heliconius melpomene TFs

134 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSCSAG00000014537 Chlorocebus sabaeus ENSCSAG00000014537 I 0.867
Otx2 Mus musculus ENSMUSG00000021848 D 0.867
Alligator_sinensis_CCG004399.1 Alligator sinensis Alligator_sinensis_CCG004399.1 N 0.867
Hsal_07660--XP_394161.1_APIME Harpegnathos saltator Hsal_07660--XP_394161.1_APIME I 0.867
OTX2 Choloepus hoffmanni ENSCHOG00000013827 I 0.854
OESDEN_16215 Oesophagostomum dentatum OESDEN_16215 N 0.844
GPLIN_000181000 Globodera pallida GPLIN_000181000 N 0.806
Ocbimv22035611m.g Octopus bimaculoides Ocbimv22035611m.g I 0.804
ENSCJAG00000011381 Callithrix jacchus ENSCJAG00000011381 N 0.796
TPRX1 Homo sapiens ENSG00000178928 I 0.794
CJA11256 Caenorhabditis japonica CJA11256 N 0.787
CGI_10007832 Crassostrea gigas CGI_10007832 N 0.783
SMTD_0001972301 Schistosoma mattheei SMTD_0001972301 N 0.781
DMBX1 Monodelphis domestica ENSMODG00000001963 N 0.779
CBG15039 Caenorhabditis briggsae CBG15039 N 0.774
OTX2 Myotis lucifugus ENSMLUG00000022591 I 0.774
AALB006874 Anopheles albimanus AALB006874 N 0.773
unc-30 Caenorhabditis elegans WBGene00006766 I 0.767
ANCCEY_04348 Ancylostoma ceylanicum ANCCEY_04348 N 0.767
TELCIR_18721 Teladorsagia circumcincta TELCIR_18721 N 0.767
pitx1 Gasterosteus aculeatus ENSGACG00000016483 I 0.763
Cmyd_10017639 Chelonia mydas Cmyd_10017639 I 0.763
TTRE_0000079401 Trichuris trichiura TTRE_0000079401 N 0.761
EFV55958 Trichinella spiralis EFV55958 N 0.754
AEPI010431 Anopheles epiroticus AEPI010431 N 0.754
WUBG_02624 Wuchereria bancrofti WUBG_02624 N 0.751
ENSLAFG00000000420 Loxodonta africana ENSLAFG00000000420 N 0.750
DPRX Choloepus hoffmanni ENSCHOG00000010851 N 0.747
XP_002164986.1 Hydra magnipapillata XP_002164986.1 N 0.743
ASIS015315 Anopheles sinensis ASIS015315 N 0.741
WUBG_02192 Wuchereria bancrofti WUBG_02192 N 0.720
ACEP26305 Atta cephalotes ACEP26305 N 0.720
ISCW006446 Ixodes scapularis ISCW006446 N 0.720
YQE_12574 Dendroctonus ponderosae YQE_12574 N 0.720
CLEC006124 Cimex lectularius CLEC006124 N 0.720
LDEC016519 Leptinotarsa decemlineata LDEC016519 N 0.720
Sjc_0128760 Schistosoma japonicum Sjc_0128760 N 0.720
snap_masked-nMf.1.1.scaf19847-processed-gene-0.1 Meloidogyne floridensis snap_masked-nMf.1.1.scaf19847-processed-gene-0.1 N 0.720
GK22279 Drosophila willistoni FBgn0224264 N 0.714
ENSSTOG00000026735 Ictidomys tridecemlineatus ENSSTOG00000026735 N 0.713
LEUTX Homo sapiens ENSG00000213921 N 0.705
LEUTX Pan troglodytes ENSPTRG00000033892 N 0.705
GB50469 Apis mellifera GB50469 N 0.703
NEMVEDRAFT_v1g48861 Nematostella vectensis NEMVEDRAFT_v1g48861 N 0.695
ENSCSAG00000003788 Chlorocebus sabaeus ENSCSAG00000003788 N 0.693
ENSPANG00000010570 Papio anubis ENSPANG00000010570 N 0.693
LDEC023625 Leptinotarsa decemlineata LDEC023625 N 0.679
ANCCEY_11895 Ancylostoma ceylanicum ANCCEY_11895 N 0.674
ENSPVAG00000005359 Pteropus vampyrus ENSPVAG00000005359 N 0.642
ENSSSCG00000002985 Sus scrofa ENSSSCG00000002985 N 0.642
ENSTTRG00000007283 Tursiops truncatus ENSTTRG00000007283 N 0.642
ENSOARG00000006291 Ovis aries ENSOARG00000006291 N 0.637
LEUTX Canis familiaris ENSCAFG00000028552 N 0.636
LEUTX Felis catus ENSFCAG00000023272 N 0.636
Hba_17538 Heterorhabditis bacteriophora Hba_17538 N 0.628
LEUTX Bos taurus ENSBTAG00000046425 N 0.623
ANCCAN_27245 Ancylostoma caninum ANCCAN_27245 N 0.622
snap_masked-nMf.1.1.scaf16485-processed-gene-0.2 Meloidogyne floridensis snap_masked-nMf.1.1.scaf16485-processed-gene-0.2 N 0.606
Traes_3AS_348CA06D5 Triticum aestivum Traes_3AS_348CA06D5 N 0.601
snap_masked-nMf.1.1.scaf03281-processed-gene-0.3 Meloidogyne floridensis snap_masked-nMf.1.1.scaf03281-processed-gene-0.3 N 0.599
AGAP000215 Anopheles gambiae AGAP000215 I 0.462
CGI_10015784 Crassostrea gigas CGI_10015784 I 0.462
DAPPUDRAFT_347230 Daphnia pulex DAPPUDRAFT_347230 I 0.462
OTX2 Anolis carolinensis ENSACAG00000011257 I 0.462
ENSAMXG00000001577 Astyanax mexicanus ENSAMXG00000001577 I 0.462
ENSAMXG00000002802 Astyanax mexicanus ENSAMXG00000002802 I 0.462
ENSAMXG00000020500 Astyanax mexicanus ENSAMXG00000020500 I 0.462
ENSAMXG00000020955 Astyanax mexicanus ENSAMXG00000020955 I 0.462
crx Danio rerio ENSDARG00000011989 I 0.462
otx1a Danio rerio ENSDARG00000030703 I 0.462
otx5 Danio rerio ENSDARG00000043483 I 0.462
otx5 Gasterosteus aculeatus ENSGACG00000005793 I 0.462
otx1b Gasterosteus aculeatus ENSGACG00000019733 I 0.462
ENSGMOG00000011885 Gadus morhua ENSGMOG00000011885 I 0.462
ENSGMOG00000014372 Gadus morhua ENSGMOG00000014372 I 0.462
ENSLACG00000012436 Latimeria chalumnae ENSLACG00000012436 I 0.462
ENSONIG00000010894 Oreochromis niloticus ENSONIG00000010894 I 0.462
ENSONIG00000016630 Oreochromis niloticus ENSONIG00000016630 I 0.462
otx1b Oryzias latipes ENSORLG00000002864 I 0.462
otx5 Oryzias latipes ENSORLG00000008681 I 0.462
ENSPFOG00000002731 Poecilia formosa ENSPFOG00000002731 I 0.462
ENSPFOG00000004008 Poecilia formosa ENSPFOG00000004008 I 0.462
ENSPMAG00000009746 Petromyzon marinus ENSPMAG00000009746 I 0.462
otx5 Tetraodon nigroviridis ENSTNIG00000014332 I 0.462
otx5 Takifugu rubripes ENSTRUG00000000498 I 0.462
ENSXMAG00000002599 Xiphophorus maculatus ENSXMAG00000002599 I 0.462
ENSXMAG00000005866 Xiphophorus maculatus ENSXMAG00000005866 I 0.462
oc Drosophila melanogaster FBgn0004102 D 0.462
GF22649 Drosophila ananassae FBgn0099643 I 0.462
GG19031 Drosophila erecta FBgn0111237 I 0.462
GH24206 Drosophila grimshawi FBgn0131662 I 0.462
GI15226 Drosophila mojavensis FBgn0137975 I 0.462
GL13044 Drosophila persimilis FBgn0150650 I 0.462
GM21160 Drosophila sechellia FBgn0176041 I 0.462
GJ19323 Drosophila virilis FBgn0206467 I 0.462
GK18379 Drosophila willistoni FBgn0220377 I 0.462
GE17437 Drosophila yakuba FBgn0234904 I 0.462
GA25945 Drosophila pseudoobscura FBgn0247322 I 0.462
oc Drosophila simulans FBgn0266091 I 0.462
GB45500 Apis mellifera GB45500 I 0.462
HelroG75373 Helobdella robusta HelroG75373 I 0.462
LotgiG194184 Lottia gigantea LotgiG194184 I 0.462
MCINX016277 Melitaea cinxia MCINX016277 I 0.462
NV16624 Nasonia vitripennis NV16624 I 0.462
RPRC000583 Rhodnius prolixus RPRC000583 I 0.462
SMAR003036 Strigamia maritima SMAR003036 I 0.462
TC003355 Tribolium castaneum TC003355 I 0.462
YQE_07373 Dendroctonus ponderosae YQE_07373 I 0.462
Cflo_05730--XP_394161.1_APIME Camponotus floridanus Cflo_05730--XP_394161.1_APIME I 0.462
Ogr08751 Ophisaurus gracilis Ogr08751 I 0.462
Pvit_18486 Pogona vitticeps Pvit_18486 I 0.462
Ocbimv22025800m.g Octopus bimaculoides Ocbimv22025800m.g I 0.462
AAB63527 Xenopus laevis AAB63527 I 0.462
crx Xenopus tropicalis XB-GENE-478452 I 0.462
otx2.L Xenopus laevis XB-GENE-485224 I 0.462
crx.S Xenopus laevis XB-GENE-6252876 I 0.462
otx2.S Xenopus laevis XB-GENE-6254039 I 0.462
crx.L Xenopus laevis XB-GENE-865179 I 0.462
otx1.L Xenopus laevis XB-GENE-939807 I 0.462
AALB009739 Anopheles albimanus AALB009739 I 0.462
AARA010546 Anopheles arabiensis AARA010546 I 0.462
AATE004648 Anopheles atroparvus AATE004648 I 0.462
ACUA003607 Anopheles culicifacies ACUA003607 I 0.462
ADIR011662 Anopheles dirus ADIR011662 I 0.462
AEPI005944 Anopheles epiroticus AEPI005944 I 0.462
AFAF010420 Anopheles farauti AFAF010420 I 0.462
AFUN000966 Anopheles funestus AFUN000966 I 0.462
AFUN010924 Anopheles funestus AFUN010924 I 0.462
AMIN005538 Anopheles minimus AMIN005538 I 0.462
AQUA007250 Anopheles quadriannulatus AQUA007250 I 0.462
ASIS021138 Anopheles sinensis ASIS021138 I 0.462
ASTEI01078 Anopheles stephensi ASTEI01078 I 0.462
MDOA009417 Musca domestica MDOA009417 I 0.462
PPAI008840 Phlebotomus papatasi PPAI008840 I 0.462