ENSSSCG00000025261 (Sus scrofa)
Runt

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00853 (Runt) IPR013524 ENSSSCG00000025261 T319491_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
RUNX3
M03464_2.00
Homo sapiens
HRACCGCAAACCRCAN

NTGYGGTTTGCGGTYD
SELEX
Jolma et al.(2013)
RUNX3_1
0.949 0.949
RUNX3
M03465_2.00
Homo sapiens
WAACCRCARN

NYTGYGGTTW
SELEX
Jolma et al.(2013)
RUNX3_2
0.949 0.949
RUNX3
M03466_2.00
Homo sapiens
HDACCRCADWAACCRCRN

NYGYGGTTWHTGYGGTHD
SELEX
Jolma et al.(2013)
RUNX3_3
0.949 0.949
RUNX3
M03467_2.00
Homo sapiens
HRACCRCAAH

DTTGYGGTYD
SELEX
Jolma et al.(2013)
RUNX3_4
0.949 0.949
RUNX3
M02751_2.00
Homo sapiens
WACCRCAM

KTGYGGTW
SELEX
Jolma et al.(2010)
RUNX3_monomer
0.949 0.949
RUNX3
M05731_2.00
Homo sapiens
YWAACCGCAAAAACCGCARV

BYTGCGGTTTTTGCGGTTWR
SELEX
Yin et al.(2017)
RUNX3_FL_HT-SELEX
0.949 0.949
RUNX3
M09369_2.00
Homo sapiens
HAACCACARN

NYTGTGGTTD
Misc
Kulakovskiy et al.(2013)
RUNX3_HUMAN.H11MO.0.A
0.949 0.949
Runx3
M09374_2.00
Mus musculus
NHRACCACARVN

NBYTGTGGTYDN
Misc
Kulakovskiy et al.(2013)
RUNX3_MOUSE.H11MO.0.A
0.949 0.949
RUNX3
M11252_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML2_Q3_01
0.949 0.949
RUNX3
M11253_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML2_Q3
0.949 0.949
RUNX3
M11254_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML2_Q4
0.949 0.949
RUNX3
M05732_2.00
Homo sapiens
HWAACCACRAAAACCACRARN

NYTYGTGGTTTTYGTGGTTWD
SELEX
Yin et al.(2017)
RUNX3_FL_Methyl-HT-SELEX
0.949 0.949
Runx2
M01307_2.00
Mus musculus
NHDACCRCAN

NTGYGGTHDN
PBM
Lambert et al.(2019)
pTH9764
0.888 0.888
RUNX2
M03468_2.00
Homo sapiens
HRACCGCAAACCRCRD

HYGYGGTTTGCGGTYD
SELEX
Jolma et al.(2013)
RUNX2_1
0.888 0.888
RUNX2
M03469_2.00
Homo sapiens
HRACCRCADWWACCRCAD

HTGYGGTWWHTGYGGTYD
SELEX
Jolma et al.(2013)
RUNX2_2
0.888 0.888
RUNX2
M03470_2.00
Homo sapiens
WAACCRCAR

YTGYGGTTW
SELEX
Jolma et al.(2013)
RUNX2_3
0.888 0.888
RUNX2
M05733_2.00
Homo sapiens
NHRACCRCADWAACCRCAVN

NBTGYGGTTWHTGYGGTYDN
SELEX
Yin et al.(2017)
RUNX2_eDBD_HT-SELEX
0.888 0.888
RUNX2
M09370_2.00
Homo sapiens
MMHAACCACAVVMH

DKBBTGTGGTTDKK
Misc
Kulakovskiy et al.(2013)
RUNX2_HUMAN.H11MO.0.A
0.888 0.888
Runx2
M09373_2.00
Mus musculus
VWRACCACARVV

BBYTGTGGTYWB
Misc
Kulakovskiy et al.(2013)
RUNX2_MOUSE.H11MO.0.A
0.888 0.888
RUNX2
M09630_2.00
Homo sapiens
NHVACCACANNN

NNNTGTGGTBDN
Misc
Heinz et al.(2010)
PCa-RUNX2_GSE33889
0.888 0.888
RUNX2
M11255_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML3_Q3
0.888 0.888
RUNX2
M11256_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML3_Q6
0.888 0.888
RUNX2
M11257_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$OSF2_Q6
0.888 0.888
RUNX2
M05734_2.00
Homo sapiens
NWAACCACRAAAACCACRRN

NYYGTGGTTTTYGTGGTTWN
SELEX
Yin et al.(2017)
RUNX2_eDBD_Methyl-HT-SELEX
0.888 0.888
Runx1
M08163_2.00
Mus musculus
HRRCCACARVN

NBYTGTGGYYD
ChIP-seq
Mathelier et al.(2014)
MA0002.2
0.878 0.878
RUNX1
M09371_2.00
Homo sapiens
NWAACCACARV

BYTGTGGTTWN
Misc
Kulakovskiy et al.(2013)
RUNX1_HUMAN.H11MO.0.A
0.878 0.878
Runx1
M09372_2.00
Mus musculus
VWRACCACARVV

BBYTGTGGTYWB
Misc
Kulakovskiy et al.(2013)
RUNX1_MOUSE.H11MO.0.A
0.878 0.878
RUNX1
M09632_2.00
Homo sapiens
HAACCACADV

BHTGTGGTTD
Misc
Heinz et al.(2010)
Jurkat-RUNX1_GSE29180
0.878 0.878
RUNX1
M09631_2.00
Homo sapiens
VCCACWTCCTBY

RVAGGAWGTGGB
Misc
Heinz et al.(2010)
Jurkat-RUNX1_GSE17954
0.878 0.878
Runx1
M09633_2.00
Mus musculus
NWAACCACAR

YTGTGGTTWN
Misc
Heinz et al.(2010)
HPC7-Runx1_GSE22178
0.878 0.878
RUNX1
M11258_2.00
Homo sapiens
ACCRCA

TGYGGT
Transfac
Matys et al.(2006)
V$AML1_01
0.878 0.878
RUNX1
M11259_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML1_Q4_01
0.878 0.878
RUNX1
M11260_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML1_Q4_02
0.878 0.878
RUNX1
M11261_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML1_Q4
0.878 0.878
RUNX1
M11262_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML1_Q5
0.878 0.878
RUNX1
M11263_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML1_Q6
0.878 0.878
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSSSCP00000020286 Runt 62 159

Links

Other Runt family TFs
Other Sus scrofa TFs

206 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSPPYG00000001714 Pongo abelii ENSPPYG00000001714 I 0.949
ENSAPLG00000016439 Anas platyrhynchos ENSAPLG00000016439 I 0.939
RUNX3 Dasypus novemcinctus ENSDNOG00000043493 I 0.939
ENSFALG00000000470 Ficedula albicollis ENSFALG00000000470 I 0.939
ENSGALG00000026821 Gallus gallus ENSGALG00000026821 I 0.939
RUNX3 Loxodonta africana ENSLAFG00000008382 I 0.939
ENSMODG00000013941 Monodelphis domestica ENSMODG00000013941 I 0.939
RUNX3 Taeniopygia guttata ENSTGUG00000001130 I 0.939
runx3 Tetraodon nigroviridis ENSTNIG00000016911 I 0.939
runx3 Takifugu rubripes ENSTRUG00000001517 I 0.939
Cmyd_10020845 Chelonia mydas Cmyd_10020845 I 0.939
runx3 Xenopus tropicalis XB-GENE-487784 I 0.939
ENSAMXG00000004048 Astyanax mexicanus ENSAMXG00000004048 I 0.929
RUNX3 Callithrix jacchus ENSCJAG00000020815 I 0.929
runx3 Danio rerio ENSDARG00000052826 I 0.929
runx3 Gasterosteus aculeatus ENSGACG00000007301 I 0.929
ENSMEUG00000014419 Macropus eugenii ENSMEUG00000014419 I 0.929
ENSOARG00000006421 Ovis aries ENSOARG00000006421 I 0.929
ENSONIG00000008210 Oreochromis niloticus ENSONIG00000008210 I 0.929
runx3 Oryzias latipes ENSORLG00000017515 I 0.929
ENSPFOG00000003997 Poecilia formosa ENSPFOG00000003997 I 0.929
ENSXMAG00000018835 Xiphophorus maculatus ENSXMAG00000018835 I 0.929
Pvit_17193 Pogona vitticeps Pvit_17193 I 0.918
RUNX1 Homo sapiens ENSG00000159216 D 0.908
ENSLOCG00000002744 Lepisosteus oculatus ENSLOCG00000002744 I 0.908
ENSP00000300305 Macaca fascicularis ENSP00000300305 I 0.908
ENSAMXG00000000881 Astyanax mexicanus ENSAMXG00000000881 I 0.898
runx2a Danio rerio ENSDARG00000040261 I 0.898
Gfo_R015914 Geospiza fortis Gfo_R015914 I 0.898
RUNX2 Anolis carolinensis ENSACAG00000013003 I 0.888
RUNX2 Bos taurus ENSBTAG00000004104 I 0.888
RUNX1 Bos taurus ENSBTAG00000004742 I 0.888
RUNX2 Cavia porcellus ENSCPOG00000005277 I 0.888
ENSCSAG00000012528 Chlorocebus sabaeus ENSCSAG00000012528 I 0.888
RUNX2 Dasypus novemcinctus ENSDNOG00000034361 I 0.888
RUNX2 Erinaceus europaeus ENSEEUG00000009243 I 0.888
RUNX2 Homo sapiens ENSG00000124813 D 0.888
RUNX2 Gorilla gorilla ENSGGOG00000012890 I 0.888
ENSLACG00000011545 Latimeria chalumnae ENSLACG00000011545 I 0.888
ENSLACG00000013776 Latimeria chalumnae ENSLACG00000013776 I 0.888
ENSLOCG00000015816 Lepisosteus oculatus ENSLOCG00000015816 I 0.888
RUNX2 Macaca mulatta ENSMMUG00000019819 I 0.888
RUNX2 Monodelphis domestica ENSMODG00000018912 I 0.888
RUNX1 Monodelphis domestica ENSMODG00000021051 I 0.888
Runx2 Mus musculus ENSMUSG00000039153 D 0.888
RUNX2 Otolemur garnettii ENSOGAG00000003900 I 0.888
RUNX2 Ochotona princeps ENSOPRG00000002943 I 0.888
ENSPANG00000006186 Papio anubis ENSPANG00000006186 I 0.888
ENSPPYG00000016664 Pongo abelii ENSPPYG00000016664 I 0.888
RUNX2 Pan troglodytes ENSPTRG00000018228 I 0.888
RUNX1 Pteropus vampyrus ENSPVAG00000001606 I 0.888
Runx2 Rattus norvegicus ENSRNOG00000020193 I 0.888
ENSSHAG00000009950 Sarcophilus harrisii ENSSHAG00000009950 I 0.888
ENSSHAG00000014782 Sarcophilus harrisii ENSSHAG00000014782 I 0.888
ENSSTOG00000010163 Ictidomys tridecemlineatus ENSSTOG00000010163 I 0.888
RUNX2 Taeniopygia guttata ENSTGUG00000013249 I 0.888
RUNX2 Tursiops truncatus ENSTTRG00000006943 I 0.888
Alligator_sinensis_CCG001676.1 Alligator sinensis Alligator_sinensis_CCG001676.1 I 0.888
Cmyd_10020455 Chelonia mydas Cmyd_10020455 I 0.888
ENSP00000409227-D1 Bos grunniens ENSP00000409227-D1 I 0.888
Pvit_01165 Pogona vitticeps Pvit_01165 I 0.888
ENSAMEG00000005325 Ailuropoda melanoleuca ENSAMEG00000005325 I 0.878
RUNX1 Canis familiaris ENSCAFG00000009596 I 0.878
RUNX1 Callithrix jacchus ENSCJAG00000002816 I 0.878
ENSCSAG00000008703 Chlorocebus sabaeus ENSCSAG00000008703 I 0.878
RUNX1 Dasypus novemcinctus ENSDNOG00000015041 I 0.878
Runx1 Dipodomys ordii ENSDORG00000004347 I 0.878
RUNX1 Equus caballus ENSECAG00000003462 I 0.878
ENSFALG00000000025 Ficedula albicollis ENSFALG00000000025 I 0.878
RUNX1 Gallus gallus ENSGALG00000016022 I 0.878
RUNX1 Gorilla gorilla ENSGGOG00000012862 I 0.878
ENSLACG00000015930 Latimeria chalumnae ENSLACG00000015930 I 0.878
RUNX1 Loxodonta africana ENSLAFG00000004290 I 0.878
RUNX1 Microcebus murinus ENSMICG00000011998 I 0.878
RUNX1 Macaca mulatta ENSMMUG00000001649 I 0.878
ENSMPUG00000001340 Mustela putorius furo ENSMPUG00000001340 I 0.878
Runx1 Mus musculus ENSMUSG00000022952 D 0.878
ENSNLEG00000004310 Nomascus leucogenys ENSNLEG00000004310 I 0.878
RUNX1 Oryctolagus cuniculus ENSOCUG00000013731 I 0.878
RUNX1 Otolemur garnettii ENSOGAG00000033362 I 0.878
ENSPANG00000007357 Papio anubis ENSPANG00000007357 I 0.878
ENSPPYG00000011394 Pongo abelii ENSPPYG00000011394 I 0.878
ENSPSIG00000017547 Pelodiscus sinensis ENSPSIG00000017547 I 0.878
RUNX1 Pan troglodytes ENSPTRG00000013883 I 0.878
RUNX2 Pteropus vampyrus ENSPVAG00000001720 I 0.878
Runx1 Rattus norvegicus ENSRNOG00000001704 I 0.878
ENSSSCG00000012051 Sus scrofa ENSSSCG00000012051 I 0.878
ENSTSYG00000005097 Tarsius syrichta ENSTSYG00000005097 I 0.878
RUNX1 Tursiops truncatus ENSTTRG00000014160 I 0.878
Cmyd_10021516 Chelonia mydas Cmyd_10021516 I 0.878
Ogr17914 Ophisaurus gracilis Ogr17914 I 0.878
Pvit_04762 Pogona vitticeps Pvit_04762 I 0.878
ENSAMXG00000017349 Astyanax mexicanus ENSAMXG00000017349 I 0.867
ENSCPOG00000002684 Cavia porcellus ENSCPOG00000002684 I 0.867
runx2b Danio rerio ENSDARG00000059233 I 0.867
ENSGMOG00000010468 Gadus morhua ENSGMOG00000010468 I 0.867
ENSONIG00000001025 Oreochromis niloticus ENSONIG00000001025 I 0.867
ENSOPRG00000000765 Ochotona princeps ENSOPRG00000000765 I 0.867
runx2 Oryzias latipes ENSORLG00000010169 I 0.867
ENSPFOG00000016115 Poecilia formosa ENSPFOG00000016115 I 0.867
runx2b Tetraodon nigroviridis ENSTNIG00000009685 I 0.867
runx2 Takifugu rubripes ENSTRUG00000003501 I 0.867
ENSXMAG00000003400 Xiphophorus maculatus ENSXMAG00000003400 I 0.867
XP_002939386 Xenopus tropicalis XP_002939386 I 0.867
XP_002939387 Xenopus tropicalis XP_002939387 I 0.867
XP_002939388 Xenopus tropicalis XP_002939388 I 0.867
runx1 Danio rerio ENSDARG00000087646 I 0.857
runx2b Gasterosteus aculeatus ENSGACG00000012322 I 0.857
RUNX3 Myotis lucifugus ENSMLUG00000003395 I 0.857
runx2.L Xenopus laevis XB-GENE-864817 I 0.857
ENSAMXG00000012244 Astyanax mexicanus ENSAMXG00000012244 I 0.847
runx2 Xenopus tropicalis XB-GENE-482021 I 0.847
runx1.L Xenopus laevis XB-GENE-864949 I 0.847
RUNX2 Equus caballus ENSECAG00000020875 I 0.837
ENSGMOG00000014088 Gadus morhua ENSGMOG00000014088 I 0.827
ENSONIG00000004914 Oreochromis niloticus ENSONIG00000004914 I 0.827
RUNX3 Pteropus vampyrus ENSPVAG00000005839 N 0.827
ENSMPUG00000015804 Mustela putorius furo ENSMPUG00000015804 I 0.816
runx1 Takifugu rubripes ENSTRUG00000012611 I 0.816
RUNX1 Gasterosteus aculeatus ENSGACG00000015276 I 0.806
ENSTNIG00000018690 Tetraodon nigroviridis ENSTNIG00000018690 I 0.806
ENSTRUG00000017865 Takifugu rubripes ENSTRUG00000017865 I 0.806
RUNX1 Oryzias latipes ENSORLG00000020699 I 0.796
ENSTGUG00000004719 Taeniopygia guttata ENSTGUG00000004719 I 0.796
HMEL009843 Heliconius melpomene HMEL009843 I 0.789
RPRC000026 Rhodnius prolixus RPRC000026 I 0.787
AALB007753 Anopheles albimanus AALB007753 I 0.787
ASIS002518 Anopheles sinensis ASIS002518 I 0.787
AARA011332 Anopheles arabiensis AARA011332 I 0.763
KGM_21075 Danaus plexippus KGM_21075 I 0.755
TC005566 Tribolium castaneum TC005566 I 0.755
TC006536 Tribolium castaneum TC006536 I 0.755
TriadG25179 Trichoplax adhaerens TriadG25179 I 0.755
ACUA002933 Anopheles culicifacies ACUA002933 I 0.755
AFAF002111 Anopheles farauti AFAF002111 I 0.755
AFUN010424 Anopheles funestus AFUN010424 I 0.755
AMEC011614 Anopheles melas AMEC011614 I 0.755
AMIN005760 Anopheles minimus AMIN005760 I 0.755
SINV13345 Solenopsis invicta SINV13345 I 0.750
CpipJ_CPIJ016826 Culex pipiens CpipJ_CPIJ016826 I 0.745
AAEL006160 Aedes aegypti AAEL006160 I 0.745
CPIJ016826 Culex quinquefasciatus CPIJ016826 I 0.745
Sakowv30005496m.g Saccoglossus kowalevskii Sakowv30005496m.g I 0.745
CLEC011123 Cimex lectularius CLEC011123 I 0.745
CLEC011127 Cimex lectularius CLEC011127 I 0.745
AATE002063 Anopheles atroparvus AATE002063 I 0.745
ACHR007816 Anopheles christyi ACHR007816 I 0.745
ASTEI07771 Anopheles stephensi ASTEI07771 I 0.745
LDEC006650 Leptinotarsa decemlineata LDEC006650 I 0.740
AAEL007036 Aedes aegypti AAEL007036 I 0.735
KGM_02818 Danaus plexippus KGM_02818 I 0.735
PHUM333300 Pediculus humanus PHUM333300 I 0.735
SMAR009403 Strigamia maritima SMAR009403 I 0.735
LDEC020505 Leptinotarsa decemlineata LDEC020505 I 0.735
ADIR001029 Anopheles dirus ADIR001029 I 0.735
AEPI011470 Anopheles epiroticus AEPI011470 I 0.735
AQUA008686 Anopheles quadriannulatus AQUA008686 I 0.735
ISCW023333 Ixodes scapularis ISCW023333 I 0.724
MCINX000302 Melitaea cinxia MCINX000302 I 0.724
NV10998 Nasonia vitripennis NV10998 I 0.724
RPRC005391 Rhodnius prolixus RPRC005391 I 0.724
SINV13317 Solenopsis invicta SINV13317 I 0.724
TC005796 Tribolium castaneum TC005796 I 0.724
YQE_12218 Dendroctonus ponderosae YQE_12218 I 0.724
Cflo_03909--XP_394016.2_APIME Camponotus floridanus Cflo_03909--XP_394016.2_APIME I 0.724
Hsal_12319--XP_394016.2_APIME Harpegnathos saltator Hsal_12319--XP_394016.2_APIME I 0.724
LCUP002657 Lucilia cuprina LCUP002657 I 0.724
LDEC003023 Leptinotarsa decemlineata LDEC003023 I 0.724
PPAI010985 Phlebotomus papatasi PPAI010985 I 0.724
LLOJ002049 Lutzomyia longipalpis LLOJ002049 I 0.717
ENSAMEG00000010102 Ailuropoda melanoleuca ENSAMEG00000010102 I 0.715
RUNX3 Canis familiaris ENSCAFG00000012903 I 0.715
ENSCPOG00000000551 Cavia porcellus ENSCPOG00000000551 I 0.715
ENSCSAG00000000947 Chlorocebus sabaeus ENSCSAG00000000947 I 0.715
RUNX3 Felis catus ENSFCAG00000000680 I 0.715
RUNX3 Homo sapiens ENSG00000020633 D 0.715
RUNX3 Gorilla gorilla ENSGGOG00000004848 I 0.715
RUNX3 Macaca mulatta ENSMMUG00000002420 I 0.715
Runx3 Mus musculus ENSMUSG00000070691 D 0.715
RUNX3 Oryctolagus cuniculus ENSOCUG00000017751 I 0.715
RUNX3 Otolemur garnettii ENSOGAG00000025633 I 0.715
RUNX3 Ochotona princeps ENSOPRG00000011273 I 0.715
ENSPANG00000008140 Papio anubis ENSPANG00000008140 I 0.715
RUNX3 Pan troglodytes ENSPTRG00000000351 I 0.715
Runx3 Rattus norvegicus ENSRNOG00000054217 I 0.715
ENSSTOG00000022471 Ictidomys tridecemlineatus ENSSTOG00000022471 I 0.715
RUNX3 Tursiops truncatus ENSTTRG00000009396 I 0.715
ACEP16391 Atta cephalotes ACEP16391 I 0.714
ACEP16397 Atta cephalotes ACEP16397 I 0.714
ACEP16409 Atta cephalotes ACEP16409 I 0.714
NV11000 Nasonia vitripennis NV11000 I 0.714
Cflo_03911--XP_394014.2_APIME Camponotus floridanus Cflo_03911--XP_394014.2_APIME I 0.714
Cflo_03913--XP_394013.3_APIME Camponotus floridanus Cflo_03913--XP_394013.3_APIME I 0.714
Hsal_04635--XP_394013.3_APIME Harpegnathos saltator Hsal_04635--XP_394013.3_APIME I 0.714
Ocbimv22002042m.g Octopus bimaculoides Ocbimv22002042m.g I 0.714
XP_002165633.1 Hydra magnipapillata XP_002165633.1 I 0.714
BGIBMGA008970 Bombyx mori BGIBMGA008970 I 0.713
ENSPSIG00000012728 Pelodiscus sinensis ENSPSIG00000012728 I 0.708
CpipJ_CPIJ006369 Culex pipiens CpipJ_CPIJ006369 I 0.704
ACYPI001442 Acyrthosiphon pisum ACYPI001442 I 0.704
ACYPI007541 Acyrthosiphon pisum ACYPI007541 I 0.704
CapteG142159 Capitella teleta CapteG142159 I 0.704
CPIJ006369 Culex quinquefasciatus CPIJ006369 I 0.704
PHUM333340 Pediculus humanus PHUM333340 I 0.704
SPU_007852 Strongylocentrotus purpuratus SPU_007852 I 0.704
runx3.L Xenopus laevis XB-GENE-6487158 I 0.700