AP-2 (Drosophila melanogaster)
AP-2

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03299 (TF_AP-2) IPR013854 FBgn0261953 T011069_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
AP-2
M03584_2.00
Drosophila melanogaster
HGCCYSRGGCD

HGCCYSRGGCD
SELEX
Nitta et al.(2015)
AP-2_1
(Direct) (Direct)
AP-2
M03585_2.00
Drosophila melanogaster
HGCCYBVRGGCD

HGCCYBVRGGCD
SELEX
Nitta et al.(2015)
AP-2_2
(Direct) (Direct)
AP-2
M03586_2.00
Drosophila melanogaster
NSCCYBNVRGGCN

NGCCYBNVRGGSN
SELEX
Nitta et al.(2015)
AP-2_3
(Direct) (Direct)
AP-2
M03587_2.00
Drosophila melanogaster
HGCCYNRGGCD

HGCCYNRGGCD
SELEX
Nitta et al.(2015)
AP-2_4
(Direct) (Direct)
AP-2
M03588_2.00
Drosophila melanogaster
HSCCYBVRGGSD

HSCCYBVRGGSD
SELEX
Nitta et al.(2015)
AP-2_5
(Direct) (Direct)
AP-2
M03589_2.00
Drosophila melanogaster
HGCCYBNVRGGCD

HGCCYBNVRGGCD
SELEX
Nitta et al.(2015)
AP-2_6
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
TFAP2E
M04050_2.00
Homo sapiens
HSCCYSRGGSD

HSCCYSRGGSD
SELEX
Yin et al.(2017)
TFAP2E_FL_HT-SELEX_1
0.708 0.708
TFAP2E
M04051_2.00
Homo sapiens
NSCCBBVGGSCA

TGSCCBVVGGSN
SELEX
Yin et al.(2017)
TFAP2E_FL_HT-SELEX_2
0.708 0.708
TFAP2E
M04052_2.00
Homo sapiens
HSCCYSRGGSD

HSCCYSRGGSD
SELEX
Yin et al.(2017)
TFAP2E_FL_Methyl-HT-SELEX_1
0.708 0.708
TFAP2E
M04053_2.00
Homo sapiens
NSCCYNRGGGCR

YGCCCYNRGGSN
SELEX
Yin et al.(2017)
TFAP2E_FL_Methyl-HT-SELEX_2
0.708 0.708
Tfap2b
M00112_2.00
Mus musculus
CCBSRGGSNW

WNSCCYSVGG
PBM
Badis et al.(2009)
Tcfap2b_3988
0.703 0.703
Tfap2e
M00114_2.00
Mus musculus
NNGCCYBVGG

CCBVRGGCNN
PBM
Badis et al.(2009)
Tcfap2e_3713
0.703 0.703
TFAP2B
M02753_2.00
Homo sapiens
HSCCYBVRGGCD

HGCCYBVRGGSD
SELEX
Jolma et al.(2013)
TFAP2B_1
0.703 0.703
TFAP2B
M02754_2.00
Homo sapiens
HGCCTSRGGCD

HGCCYSAGGCD
SELEX
Jolma et al.(2013)
TFAP2B_2
0.703 0.703
TFAP2B
M02755_2.00
Homo sapiens
WGCCCYBVRGGCD

HGCCYBVRGGGCW
SELEX
Jolma et al.(2013)
TFAP2B_3
0.703 0.703
TFAP2B
M04046_2.00
Homo sapiens
NSCCBNVGGSN

NSCCBNVGGSN
SELEX
Yin et al.(2017)
TFAP2B_eDBD_HT-SELEX
0.703 0.703
TFAP2B
M08701_2.00
Homo sapiens
GSCYGVGGRV

BYCCBCRGSC
Misc
Kulakovskiy et al.(2013)
AP2B_HUMAN.H11MO.0.B
0.703 0.703
Tfap2b
M08705_2.00
Mus musculus
GSCYGVGGRV

BYCCBCRGSC
Misc
Kulakovskiy et al.(2013)
AP2B_MOUSE.H11MO.0.B
0.703 0.703
TFAP2B
M09750_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AP2BETA_Q3
0.703 0.703
TFAP2B
M04047_2.00
Homo sapiens
NSCCYNRGGSD

HSCCYNRGGSN
SELEX
Yin et al.(2017)
TFAP2B_eDBD_Methyl-HT-SELEX
0.703 0.703
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0078072 AP-2 239 439
FBpp0078073 AP-2 235 435
FBpp0305655 AP-2 233 433
FBpp0305656 AP-2 245 445
FBpp0305657 AP-2 241 441
FBpp0305658 AP-2 239 439

Links

Other AP-2 family TFs
Other Drosophila melanogaster TFs

191 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
GD14977 Drosophila simulans FBgn0186649 I 1.000
GE19777 Drosophila yakuba FBgn0237110 I 1.000
GG16206 Drosophila erecta FBgn0108441 I 1.000
GF23730 Drosophila ananassae FBgn0100724 I 1.000
GM22388 Drosophila sechellia FBgn0177258 I 1.000
GE23038 Drosophila yakuba FBgn0240239 I 1.000
GA28469 Drosophila pseudoobscura FBgn0249829 I 0.995
GL18109 Drosophila persimilis FBgn0155712 I 0.995
GI11327 Drosophila mojavensis FBgn0134088 I 0.990
GH14383 Drosophila grimshawi FBgn0121859 I 0.990
GJ11582 Drosophila virilis FBgn0198839 I 0.990
GK18142 Drosophila willistoni FBgn0220141 I 0.990
MDOA012106 Musca domestica MDOA012106 I 0.969
LCUP016885 Lucilia cuprina LCUP016885 I 0.964
ENSSARG00000001996 Sorex araneus ENSSARG00000001996 I 0.955
ENSMEUG00000007703 Macropus eugenii ENSMEUG00000007703 I 0.940
tfap2b Danio rerio ENSDARG00000012667 I 0.932
ENSGACG00000002672 Gasterosteus aculeatus ENSGACG00000002672 I 0.932
ENSGMOG00000009513 Gadus morhua ENSGMOG00000009513 I 0.932
MCINX002204 Melitaea cinxia MCINX002204 I 0.925
ACEP15405 Atta cephalotes ACEP15405 I 0.921
TFAP2A Homo sapiens ENSG00000137203 D 0.899
ECPE_0000534101 Echinostoma caproni ECPE_0000534101 I 0.898
D917_08051 Trichinella nativa D917_08051 I 0.895
TFAP2D Microcebus murinus ENSMICG00000005507 I 0.889
Sakowv30010957m.g Saccoglossus kowalevskii Sakowv30010957m.g I 0.888
SPER_0000909201 Spirometra erinaceieuropaei SPER_0000909201 I 0.851
CpipJ_CPIJ013984 Culex pipiens CpipJ_CPIJ013984 I 0.821
CPIJ013984 Culex quinquefasciatus CPIJ013984 I 0.821
LLOJ007971 Lutzomyia longipalpis LLOJ007971 I 0.821
AAEL006932 Aedes aegypti AAEL006932 I 0.821
AQUA002126 Anopheles quadriannulatus AQUA002126 I 0.810
ASIS021760 Anopheles sinensis ASIS021760 I 0.810
GB50795 Apis mellifera GB50795 I 0.810
AGAP011625 Anopheles gambiae AGAP011625 I 0.810
AMAM003187 Anopheles maculatus AMAM003187 I 0.810
AFAF007133 Anopheles farauti AFAF007133 I 0.810
AMEM004222 Anopheles merus AMEM004222 I 0.810
AMIN008818 Anopheles minimus AMIN008818 I 0.810
ADIR000123 Anopheles dirus ADIR000123 I 0.810
NV15391 Nasonia vitripennis NV15391 I 0.810
AEPI000456 Anopheles epiroticus AEPI000456 I 0.810
AATE014474 Anopheles atroparvus AATE014474 I 0.810
ACOM041150 Anopheles coluzzii ACOM041150 I 0.810
ACUA015133 Anopheles culicifacies ACUA015133 I 0.810
AARA002676 Anopheles arabiensis AARA002676 I 0.810
ASTEI10011 Anopheles stephensi ASTEI10011 I 0.810
AALB003833 Anopheles albimanus AALB003833 I 0.810
AFUN005769 Anopheles funestus AFUN005769 I 0.810
ACUA011434 Anopheles culicifacies ACUA011434 I 0.807
RPRC006848 Rhodnius prolixus RPRC006848 I 0.801
PEQ_0000626601 Parascaris equorum PEQ_0000626601 I 0.800
PHUM549810 Pediculus humanus PHUM549810 I 0.795
ACYPI000357 Acyrthosiphon pisum ACYPI000357 I 0.786
snap_masked-nMf.1.1.scaf31395-processed-gene-0.2 Meloidogyne floridensis snap_masked-nMf.1.1.scaf31395-processed-gene-0.2 I 0.786
TC009922 Tribolium castaneum TC009922 I 0.786
TFAP2A Tursiops truncatus ENSTTRG00000012832 I 0.786
L798_10151 Zootermopsis nevadensis L798_10151 I 0.785
SINV20015 Solenopsis invicta SINV20015 I 0.782
YQE_10574 Dendroctonus ponderosae YQE_10574 I 0.781
LDEC004787 Leptinotarsa decemlineata LDEC004787 I 0.781
Hba_07416 Heterorhabditis bacteriophora Hba_07416 I 0.780
DAPPUDRAFT_330596 Daphnia pulex DAPPUDRAFT_330596 I 0.779
TFAP2A Erinaceus europaeus ENSEEUG00000002713 I 0.779
ANCCEY_07283 Ancylostoma ceylanicum ANCCEY_07283 I 0.773
nAv.1.0.1.g06665 Acanthocheilonema viteae nAv.1.0.1.g06665 I 0.773
PPA19579 Pristionchus pacificus PPA19579 I 0.769
ENSVPAG00000012139 Vicugna pacos ENSVPAG00000012139 I 0.767
Sjc_0121700 Schistosoma japonicum Sjc_0121700 I 0.766
KGM_21443 Danaus plexippus KGM_21443 I 0.763
tfap2b Tetraodon nigroviridis ENSTNIG00000014240 I 0.758
GPLIN_001548200 Globodera pallida GPLIN_001548200 I 0.754
TELCIR_24906 Teladorsagia circumcincta TELCIR_24906 I 0.750
tetur36g00810 Tetranychus urticae tetur36g00810 I 0.749
AMEC019970 Anopheles melas AMEC019970 I 0.749
OFLC_0000811001 Onchocerca flexuosa OFLC_0000811001 I 0.741
nOo.2.0.1.g09186 Onchocerca ochengi nOo.2.0.1.g09186 I 0.738
HMEL016834 Heliconius melpomene HMEL016834 I 0.733
CGI_10015578 Crassostrea gigas CGI_10015578 I 0.733
ENSLACG00000015883 Latimeria chalumnae ENSLACG00000015883 I 0.723
SPU_016685 Strongylocentrotus purpuratus SPU_016685 I 0.718
Smp_157840 Schistosoma mansoni Smp_157840 I 0.714
Aan_R015525 Calypte anna Aan_R015525 I 0.713
tfap2e.L Xenopus laevis XB-GENE-876809 I 0.713
TFAP2E Otolemur garnettii ENSOGAG00000029197 I 0.713
TFAP2E Bos taurus ENSBTAG00000001959 I 0.713
yakG031910 Bos grunniens yakG031910 I 0.713
tfap2e Xenopus tropicalis XB-GENE-876803 I 0.713
Pvit_04260 Pogona vitticeps Pvit_04260 I 0.713
TFAP2E Tursiops truncatus ENSTTRG00000007258 I 0.710
TFAP2E Homo sapiens ENSG00000116819 D 0.708
ENSFALG00000000745 Ficedula albicollis ENSFALG00000000745 I 0.708
TFAP2E Equus caballus ENSECAG00000003027 I 0.708
ENSETEG00000019509 Echinops telfairi ENSETEG00000019509 I 0.708
ENSGALG00000002393 Gallus gallus ENSGALG00000002393 I 0.708
ENSMGAG00000004014 Meleagris gallopavo ENSMGAG00000004014 I 0.708
ENSLOCG00000013190 Lepisosteus oculatus ENSLOCG00000013190 I 0.708
ENSGMOG00000000705 Gadus morhua ENSGMOG00000000705 I 0.708
TFAP2E Gorilla gorilla ENSGGOG00000009762 I 0.708
TFAP2E Dasypus novemcinctus ENSDNOG00000036871 I 0.708
tfap2a Danio rerio ENSDARG00000059279 I 0.708
ENSAMEG00000000718 Ailuropoda melanoleuca ENSAMEG00000000718 I 0.708
TFAP2B Anolis carolinensis ENSACAG00000005251 I 0.708
Afo_R013926 Aptenodytes forsteri Afo_R013926 I 0.708
ENSAPLG00000010002 Anas platyrhynchos ENSAPLG00000010002 I 0.708
TFAP2E Callithrix jacchus ENSCJAG00000001531 I 0.708
ENSCSAG00000001086 Chlorocebus sabaeus ENSCSAG00000001086 I 0.708
TFAP2E Cavia porcellus ENSCPOG00000024445 I 0.708
GPUH_0002219901 Gongylonema pulchrum GPUH_0002219901 I 0.708
ENSMPUG00000014894 Mustela putorius furo ENSMPUG00000014894 I 0.708
ENSOARG00000019518 Ovis aries ENSOARG00000019518 I 0.708
ENSPPYG00000001556 Pongo abelii ENSPPYG00000001556 I 0.708
ENSPFOG00000016070 Poecilia formosa ENSPFOG00000016070 I 0.708
ENSXMAG00000005803 Xiphophorus maculatus ENSXMAG00000005803 I 0.708
tfap2a Takifugu rubripes ENSTRUG00000005798 I 0.708
ENSPSIG00000011168 Pelodiscus sinensis ENSPSIG00000011168 I 0.708
TFAP2E Taeniopygia guttata ENSTGUG00000001672 I 0.708
Gfo_R008463 Geospiza fortis Gfo_R008463 I 0.708
ENSSTOG00000001781 Ictidomys tridecemlineatus ENSSTOG00000001781 I 0.708
TFAP2E Ochotona princeps ENSOPRG00000012238 I 0.708
tfap2c Xenopus tropicalis XB-GENE-488671 I 0.708
Pvit_00888 Pogona vitticeps Pvit_00888 I 0.708
Alligator_sinensis_CCG014924.1 Alligator sinensis Alligator_sinensis_CCG014924.1 I 0.708
ENSSHAG00000016887 Sarcophilus harrisii ENSSHAG00000016887 I 0.708
Tfap2e Rattus norvegicus ENSRNOG00000027595 I 0.708
ENSONIG00000006816 Oreochromis niloticus ENSONIG00000006816 I 0.708
Cmyd_10020449 Chelonia mydas Cmyd_10020449 I 0.703
Brh_R005153 Buceros rhinoceros Brh_R005153 I 0.703
Brh_R009982 Buceros rhinoceros Brh_R009982 I 0.703
ENSP00000263046-D1 Bos grunniens ENSP00000263046-D1 I 0.703
tfap2b.L Xenopus laevis XB-GENE-1188127 I 0.703
tfap2b Xenopus tropicalis XB-GENE-485026 I 0.703
Myotis_brandtii_Tcfap2e_10028879 Myotis brandtii Myotis_brandtii_Tcfap2e_10028879 I 0.703
ENSP00000263046 Macaca fascicularis ENSP00000263046 I 0.703
Myotis_brandtii_TFAP2B_10011888 Myotis brandtii Myotis_brandtii_TFAP2B_10011888 I 0.703
Gfo_R000728 Geospiza fortis Gfo_R000728 I 0.703
TFAP2B Taeniopygia guttata ENSTGUG00000013267 I 0.703
TFAP2B Gallus gallus ENSGALG00000016680 I 0.703
TFAP2B Gorilla gorilla ENSGGOG00000014613 I 0.703
TFAP2B Homo sapiens ENSG00000008196 D 0.703
TFAP2B Felis catus ENSFCAG00000015482 I 0.703
ENSFALG00000012772 Ficedula albicollis ENSFALG00000012772 I 0.703
ENSLACG00000009501 Latimeria chalumnae ENSLACG00000009501 I 0.703
TFAP2B Loxodonta africana ENSLAFG00000027209 I 0.703
ENSMLUG00000009852 Myotis lucifugus ENSMLUG00000009852 I 0.703
TFAP2B Myotis lucifugus ENSMLUG00000016209 I 0.703
ENSMGAG00000014245 Meleagris gallopavo ENSMGAG00000014245 I 0.703
ENSLOCG00000000725 Lepisosteus oculatus ENSLOCG00000000725 I 0.703
TFAP2E Loxodonta africana ENSLAFG00000029444 I 0.703
TFAP2B Equus caballus ENSECAG00000015046 I 0.703
TFAP2B Dasypus novemcinctus ENSDNOG00000041262 I 0.703
ENSAMXG00000005947 Astyanax mexicanus ENSAMXG00000005947 I 0.703
ENSAPLG00000013905 Anas platyrhynchos ENSAPLG00000013905 I 0.703
ENSAMEG00000008680 Ailuropoda melanoleuca ENSAMEG00000008680 I 0.703
ENSACAG00000017357 Anolis carolinensis ENSACAG00000017357 I 0.703
TFAP2C Anolis carolinensis ENSACAG00000016089 I 0.703
TFAP2B Bos taurus ENSBTAG00000020426 I 0.703
TFAP2B Canis familiaris ENSCAFG00000002156 I 0.703
tfap2c Danio rerio ENSDARG00000040606 I 0.703
ENSCSAG00000012975 Chlorocebus sabaeus ENSCSAG00000012975 I 0.703
TFAP2B Cavia porcellus ENSCPOG00000022967 I 0.703
TFAP2B Callithrix jacchus ENSCJAG00000011561 I 0.703
TFAP2B Macaca mulatta ENSMMUG00000002869 I 0.703
TFAP2E Monodelphis domestica ENSMODG00000017904 I 0.703
TFAP2B Pan troglodytes ENSPTRG00000018269 I 0.703
TFAP2B Pteropus vampyrus ENSPVAG00000007479 I 0.703
TFAP2E Pan troglodytes ENSPTRG00000000523 I 0.703
ENSPSIG00000008002 Pelodiscus sinensis ENSPSIG00000008002 I 0.703
ENSPPYG00000016700 Pongo abelii ENSPPYG00000016700 I 0.703
Tfap2b Rattus norvegicus ENSRNOG00000011823 I 0.703
ENSSHAG00000012585 Sarcophilus harrisii ENSSHAG00000012585 I 0.703
tfap2c Takifugu rubripes ENSTRUG00000013876 I 0.703
tfap2c Tetraodon nigroviridis ENSTNIG00000003840 I 0.703
ENSSTOG00000025602 Ictidomys tridecemlineatus ENSSTOG00000025602 I 0.703
TFAP2B Sus scrofa ENSSSCG00000025535 I 0.703
Alligator_sinensis_CCG010010.1 Alligator sinensis Alligator_sinensis_CCG010010.1 I 0.703
ENSPANG00000026000 Papio anubis ENSPANG00000026000 I 0.703
TFAP2B Ornithorhynchus anatinus ENSOANG00000003130 I 0.703
Tfap2e Mus musculus ENSMUSG00000042477 D 0.703
Tfap2b Mus musculus ENSMUSG00000025927 D 0.703
ENSMPUG00000009084 Mustela putorius furo ENSMPUG00000009084 I 0.703
ENSOARG00000012828 Ovis aries ENSOARG00000012828 I 0.703
TFAP2E Oryctolagus cuniculus ENSOCUG00000013190 I 0.703
TFAP2B Ochotona princeps ENSOPRG00000010247 I 0.703
Aan_R002198 Calypte anna Aan_R002198 I 0.703
TFAP2B Otolemur garnettii ENSOGAG00000000701 I 0.703
TFAP2B Oryctolagus cuniculus ENSOCUG00000025542 I 0.703
Afo_R003239 Aptenodytes forsteri Afo_R003239 I 0.701
ENSPFOG00000001600 Poecilia formosa ENSPFOG00000001600 I 0.701
ENSONIG00000013632 Oreochromis niloticus ENSONIG00000013632 I 0.701