ENSP00000204517 (Macaca fascicularis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 ENSP00000204517 T047181_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).[supplied by OMIM, Jul 2009]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Tfap4
M01717_2.00
Mus musculus
VHCABVYGB

VCRBVTGDB
PBM
Weirauch et al.(2014)
pTH5067
0.914 1.000
TFAP4
M02776_2.00
Homo sapiens
AWCAGCTGWY

RWCAGCTGWT
SELEX
Jolma et al.(2013)
TFAP4_1
0.914 1.000
TFAP4
M02777_2.00
Homo sapiens
AWCAGCTGWT

AWCAGCTGWT
SELEX
Jolma et al.(2013)
TFAP4_2
0.914 1.000
TFAP4
M04066_2.00
Homo sapiens
VHCAKVTGDB

VHCABMTGDB
SELEX
Yin et al.(2017)
TFAP4_eDBD_HT-SELEX_1
0.914 1.000
TFAP4
M04067_2.00
Homo sapiens
VWCAGCTGWB

VWCAGCTGWB
SELEX
Yin et al.(2017)
TFAP4_eDBD_HT-SELEX_2
0.914 1.000
TFAP4
M04070_2.00
Homo sapiens
RHCAYVTGDB

VHCABRTGDY
SELEX
Yin et al.(2017)
TFAP4_FL_HT-SELEX_1
0.914 1.000
TFAP4
M04071_2.00
Homo sapiens
VHCAGCTGDB

VHCAGCTGDB
SELEX
Yin et al.(2017)
TFAP4_FL_HT-SELEX_2
0.914 1.000
TFAP4
M08712_2.00
Homo sapiens
VMNCAGCTGR

YCAGCTGNKB
Misc
Kulakovskiy et al.(2013)
TFAP4_HUMAN.H11MO.0.A
0.914 1.000
TFAP4
M09453_2.00
Homo sapiens
NVHCAGCTGD

HCAGCTGDBN
Misc
Heinz et al.(2010)
AML-Tfap4_GSE45738
0.914 1.000
TFAP4
M09802_2.00
Homo sapiens
MNGNCHVCAGCTGDBBBW

WVVVHCAGCTGBDGNCNK
Transfac
Matys et al.(2006)
V$AP4_01
0.914 1.000
TFAP4
M09803_2.00
Homo sapiens
NNSAGCTGHB

VDCAGCTSNN
Transfac
Matys et al.(2006)
V$AP4_Q5
0.914 1.000
TFAP4
M09804_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AP4_Q6_01
0.914 1.000
TFAP4
M09805_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AP4_Q6_02
0.914 1.000
TFAP4
M09806_2.00
Homo sapiens
NVCAGCTGHB

VDCAGCTGBN
Transfac
Matys et al.(2006)
V$AP4_Q6
0.914 1.000
TFAP4
M04068_2.00
Homo sapiens
DHCABMTGDN

NHCAKVTGDH
SELEX
Yin et al.(2017)
TFAP4_eDBD_Methyl-HT-SELEX_1
0.914 1.000
TFAP4
M04069_2.00
Homo sapiens
AWCAGCTGWT

AWCAGCTGWT
SELEX
Yin et al.(2017)
TFAP4_eDBD_Methyl-HT-SELEX_2
0.914 1.000
TFAP4
M04072_2.00
Homo sapiens
VHCABVTGDB

VHCABVTGDB
SELEX
Yin et al.(2017)
TFAP4_FL_Methyl-HT-SELEX_1
0.914 1.000
TFAP4
M04073_2.00
Homo sapiens
VHCAGCTGDB

VHCAGCTGDB
SELEX
Yin et al.(2017)
TFAP4_FL_Methyl-HT-SELEX_2
0.914 1.000
crp
M03595_2.00
Drosophila melanogaster
AACAGCTGWT

AWCAGCTGTT
SELEX
Nitta et al.(2015)
crp_1
0.843 0.808
crp
M05937_2.00
Drosophila melanogaster
VAHCAGCTGAY

RTCAGCTGDWB
B1H
Zhu et al.(2011)
crp_SANGER_10_FBgn0001994
0.843 0.808
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000204517 bHLH 49 100

Links

Other bHLH family TFs
Other Macaca fascicularis TFs

103 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action