Mga (Rattus norvegicus)
bHLH,T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH)
PF00907 (T-box) 		IPR001092
IPR001699 		ENSRNOG00000006378 T055477_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be part of MLL1 complex and transcription regulator complex. Orthologous to human MGA (MAX dimerization protein MGA). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MGA
M02821_2.00 		Homo sapiens
RGGTGTGA
TCACACCY		 SELEX
Jolma et al.(2013)
MGA_1 		0.974 0.974
MGA
M02822_2.00 		Homo sapiens
AGGTGTKAHDTMACACCT
AGGTGTKAHDTMACACCT		 SELEX
Jolma et al.(2013)
MGA_2 		0.974 0.974
MGA
M02823_2.00 		Homo sapiens
VGTGTKAWWWTTCACRCB
VGYGTGAAWWWTMACACB		 SELEX
Jolma et al.(2013)
MGA_3 		0.974 0.974
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000008528 T-box 77 260
ENSRNOP00000008528 bHLH 2365 2416
ENSRNOP00000060349 T-box 77 260
ENSRNOP00000060349 bHLH 2195 2246
ENSRNOP00000060519 T-box 77 260
ENSRNOP00000060519 bHLH 2404 2455
ENSRNOP00000061447 T-box 77 260
ENSRNOP00000061447 bHLH 2286 2337

Links

Other bHLH,T-box family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

47 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action