ENSP00000219905 (Macaca fascicularis)
bHLH,T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH)
PF00907 (T-box) 		IPR001092
IPR001699 		ENSP00000219905 T055490_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Part of MLL1 complex. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MGA
M02821_2.00 		Homo sapiens
RGGTGTGA
TCACACCY		 SELEX
Jolma et al.(2013)
MGA_1 		1.000 1.000
MGA
M02822_2.00 		Homo sapiens
AGGTGTKAHDTMACACCT
AGGTGTKAHDTMACACCT		 SELEX
Jolma et al.(2013)
MGA_2 		1.000 1.000
MGA
M02823_2.00 		Homo sapiens
VGTGTKAWWWTTCACRCB
VGYGTGAAWWWTMACACB		 SELEX
Jolma et al.(2013)
MGA_3 		1.000 1.000
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000219905 T-box 77 260
ENSP00000219905 bHLH 2479 2530

Links

Other bHLH,T-box family TFs
Other Macaca fascicularis TFs

47 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
MGA Gorilla gorilla ENSGGOG00000001640 I 1.000
ENSCSAG00000007832 Chlorocebus sabaeus ENSCSAG00000007832 I 1.000
MGA Homo sapiens ENSG00000174197 D 1.000
ENSNLEG00000003750 Nomascus leucogenys ENSNLEG00000003750 I 1.000
ENSPPYG00000006380 Pongo abelii ENSPPYG00000006380 I 1.000
MGA Pan troglodytes ENSPTRG00000006953 I 1.000
ENSTSYG00000014605 Tarsius syrichta ENSTSYG00000014605 I 0.996
MGA Tupaia belangeri ENSTBEG00000002010 I 0.996
MGA Callithrix jacchus ENSCJAG00000020688 I 0.996
MGA Otolemur garnettii ENSOGAG00000016028 I 0.991
MGA Microcebus murinus ENSMICG00000001788 I 0.991
ENSOARG00000020404 Ovis aries ENSOARG00000020404 I 0.991
MGA Sorex araneus ENSSARG00000007043 I 0.991
ENSAMEG00000016587 Ailuropoda melanoleuca ENSAMEG00000016587 I 0.991
MGA Canis familiaris ENSCAFG00000009662 I 0.991
MGA Tursiops truncatus ENSTTRG00000002514 I 0.991
MGA Felis catus ENSFCAG00000007347 I 0.991
MGA Equus caballus ENSECAG00000006544 I 0.991
ENSMPUG00000008968 Mustela putorius furo ENSMPUG00000008968 I 0.991
MGA Pteropus vampyrus ENSPVAG00000013732 I 0.991
MGA Bos taurus ENSBTAG00000015138 I 0.987
MGA Vicugna pacos ENSVPAG00000006239 I 0.987
MGA Oryctolagus cuniculus ENSOCUG00000006505 I 0.987
MGA Myotis lucifugus ENSMLUG00000015227 I 0.987
MGA Choloepus hoffmanni ENSCHOG00000012044 I 0.987
ENSP00000219905-D1 Bos grunniens ENSP00000219905-D1 I 0.987
ENSSTOG00000000653 Ictidomys tridecemlineatus ENSSTOG00000000653 I 0.987
MGA Erinaceus europaeus ENSEEUG00000004604 I 0.983
Mga Mus musculus ENSMUSG00000033943 I 0.974
Mga Rattus norvegicus ENSRNOG00000006378 I 0.974
MGA Monodelphis domestica ENSMODG00000000052 I 0.940
MGA Procavia capensis ENSPCAG00000013131 I 0.932
Cmyd_10013542 Chelonia mydas Cmyd_10013542 I 0.927
MGA Meleagris gallopavo ENSMGAG00000011293 I 0.919
Afo_R002341 Aptenodytes forsteri Afo_R002341 I 0.915
Myotis_brandtii_MGA_10023843 Myotis brandtii Myotis_brandtii_MGA_10023843 I 0.910
Gfo_R014126 Geospiza fortis Gfo_R014126 I 0.910
ENSGALG00000008653 Gallus gallus ENSGALG00000008653 I 0.910
Ogr06446 Ophisaurus gracilis Ogr06446 I 0.906
MGA Ornithorhynchus anatinus ENSOANG00000004502 I 0.906
ENSFALG00000006030 Ficedula albicollis ENSFALG00000006030 I 0.906
ENSAPLG00000010304 Anas platyrhynchos ENSAPLG00000010304 I 0.897
Aan_R008874 Calypte anna Aan_R008874 I 0.889
Pvit_03503 Pogona vitticeps Pvit_03503 I 0.880
ENSLACG00000002619 Latimeria chalumnae ENSLACG00000002619 I 0.859
XP_002933783 Xenopus tropicalis XP_002933783 I 0.838
ENSLOCG00000011689 Lepisosteus oculatus ENSLOCG00000011689 I 0.769